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Lion's mane mushroom on the nervous system and brain function


Darwin
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Summer 2013: started on Prozac for OCD

Fall 2013: started Lexapro due to Prozac zombie effects

 

Stopped Lexapro because of lack of empathy/emotion,anxiety,lack of concentration etc.

Fall 2014: switched to zoloft 

 

February 2015: started effexor quit C/D after 2 weeks.

April 2015: was on zoloft for a month again to try and wean a bit more slowly. DID not work.

May 2015: dumped all of my medications

July 2015: Struggling day to day with withdrawal symptoms but hopeful that I'll be better at the end of august for the next school year.

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Interesting. Thanks for posting. I found this article on pubmed. It can be viewed at no cost. There were almost 200. I didn't see human trials but I didn't look at all of them. I can't help wondering if it'd help with antidepressant withdrawal.

 

http://www.ncbi.nlm.nih.gov/pubmed/25574220

Exp Ther Med. 2015 Feb;9(2):483-487. Epub 2014 Dec 16.

Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus.

Liu J1, DU C1, Wang Y1, Yu Z2.

 

Abstract Hericium erinaceus (HEP) is a notable medicinal fungus grown in China and other oriental countries. Polysaccharides from HEP have recently attracted considerable attention due to their numerous physiological activities. The objective of this study was to evaluate the anti-fatigue activity of HEP in a mouse model.

 

After one week of acclimation, mice were randomly divided into four groups: a control group, a low-dose HEP-treated group, a moderate-dose HEP-treated group, and a high-dose HEP-treated group. The treated groups received HEP (50, 100 and 200 mg/kg, ig), while the control group received saline solution.

 

Following treatment for 28 days, the mice performed a forced swimming test until they were exhausted, then the exhaustive swimming time was recorded along with certain biochemical parameters related to fatigue, including blood lactic acid (BLA), serum urea nitrogen (SUN), tissue glycogen, superoxide dismutase (SOD), glutathione peroxidase (GPx) and malondialdehyde (MDA).

 

These results suggested that HEP has significant anti-fatigue activity by decreasing BLA, SUN and MDA content, as well as increasing tissue glycogen content and antioxidant enzyme activity.

 

Based on these results, this study provided theoretical support for the application of HEP in the field of sports nutrition.

 

2009: Cancer hospital said I had adjustment disorder because I thought they were doing it wrong. Their headshrinker prescribed Effexor, and my life set on a new course. I didn't know what was ahead, like a passenger on Disneyland's Matterhorn, smiling and waving as it climbs...clink, clink, clink.

2010: Post surgical accidental Effexor discontinuation by nurses, masked by intravenous Dilaudid. (The car is balanced at the top of the track.) I get home, pop a Vicodin, and ...

Whooosh...down, down, down, down, down...goes the trajectory of my life, up goes my mood and tendency to think everything is a good idea.
2012: After the bipolar jig was up, now a walking bag of unrelated symptoms, I went crazy on Daytrana (the Ritalin skin patch by Noven), because ADHD was a perfect fit for a bag of unrelated symptoms. I was prescribed Effexor for the nervousness of it, and things got neurological. An EEG showed enough activity to warrant an epilepsy diagnosis rather than non-epileptic ("psychogenic") seizures.

:o 2013-2014: Quit everything and got worse. I probably went through DAWS: dopamine agonist withdrawal syndrome. I drank to not feel, but I felt a lot: dread, fear, regret, grief: an utter sense of total loss of everything worth breathing about, for almost two years.

I was not suicidal but I wanted to be dead, at least dead to the experience of my own brain and body.

2015: I  began to recover after adding virgin coconut oil and organic grass-fed fed butter to a cup of instant coffee in the morning.

I did it hoping for mental acuity and better memory. After ten days of that, I was much better, mood-wise. Approximately neutral.

And, I experienced drowsiness. I could sleep. Not exactly happy, I did 30 days on Wellbutrin, because it had done me no harm in the past. 

I don't have the DAWS mood or state of mind. It never feel like doing anything if it means standing up.

In fact, I don't especially like moving. I'm a brain with a beanbag body.   :unsure:

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Interesting. Thanks for posting. I found this article on pubmed. It can be viewed at no cost. There were almost 200. I didn't see human trials but I didn't look at all of them. I can't help wondering if it'd help with antidepressant withdrawal.

 

http://www.ncbi.nlm.nih.gov/pubmed/25574220

Exp Ther Med. 2015 Feb;9(2):483-487. Epub 2014 Dec 16.

Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus.

Liu J1, DU C1, Wang Y1, Yu Z2.

 

Abstract Hericium erinaceus (HEP) is a notable medicinal fungus grown in China and other oriental countries. Polysaccharides from HEP have recently attracted considerable attention due to their numerous physiological activities. The objective of this study was to evaluate the anti-fatigue activity of HEP in a mouse model.

 

After one week of acclimation, mice were randomly divided into four groups: a control group, a low-dose HEP-treated group, a moderate-dose HEP-treated group, and a high-dose HEP-treated group. The treated groups received HEP (50, 100 and 200 mg/kg, ig), while the control group received saline solution.

 

Following treatment for 28 days, the mice performed a forced swimming test until they were exhausted, then the exhaustive swimming time was recorded along with certain biochemical parameters related to fatigue, including blood lactic acid (BLA), serum urea nitrogen (SUN), tissue glycogen, superoxide dismutase (SOD), glutathione peroxidase (GPx) and malondialdehyde (MDA).

 

These results suggested that HEP has significant anti-fatigue activity by decreasing BLA, SUN and MDA content, as well as increasing tissue glycogen content and antioxidant enzyme activity.

 

Based on these results, this study provided theoretical support for the application of HEP in the field of sports nutrition.

 

just ordered myself a pound of this stuff going to see if it helps

Summer 2013: started on Prozac for OCD

Fall 2013: started Lexapro due to Prozac zombie effects

 

Stopped Lexapro because of lack of empathy/emotion,anxiety,lack of concentration etc.

Fall 2014: switched to zoloft 

 

February 2015: started effexor quit C/D after 2 weeks.

April 2015: was on zoloft for a month again to try and wean a bit more slowly. DID not work.

May 2015: dumped all of my medications

July 2015: Struggling day to day with withdrawal symptoms but hopeful that I'll be better at the end of august for the next school year.

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