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Wellbutrin100SR: How can I withdraw from Wellbutrin SR 100 after taking it for two weeks once a day in morning?


Wellbutrin100SR

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I have PTSD and depression. I take Luvox 300mg in AM, Risperidal 3.5 mg at night with Ambien 10 mg.

I started Wellbutrin SR 100mg once daily in the morning with my Luvox 300mg in the morning to help with a depression I was having. I have been taking the Wellbutrin for two weeks. The wellbutrin I believe is negatively affecting my sleep giving me insomnia and making me anxious in the morning making my PTSD worse.Thus I would like to know how to taper safely off the wellbutrin SR 100.

Thank you.

W.

I have withdrawn myself off of many medications with and/or without doctor including seroquel,invega,zyprexa,paxil,

depakote,effexor,zoloft,mirtazapine etc.

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  • Moderator Emeritus

Welcome Wellbutrin100SR

Thanks for posting.

 

You haven't been on Wellbutrin very long and its one of the easier antidepressants to taper from, so I don't think you need to do the 10% per month taper we usually recommend here.

 

Although I don't suggest you just stop it cold turkey either, or you might experience some symptoms. If I were you, I would reduce by 25% every 3 - 4 days, so you would go from 100mg down to 0mg in about 2 weeks, about the time you have been taking it.

 

This can be done by cutting your tablet into quarters.

 

 

"Data from the manufacturer states that dividing Wellbutrin SR® tablets resulted in an increased rate of release at 15 minutes: “However, the divided tablet retained its sustained-release characteristics with similar increases of released bupropion at each sampling point beyond 15 minutes when compared to the intact Wellbutrin SR® tablet...” Bupropion is hydroscopic and therefore should be stored in a dry place. Splitting of large quantities in advance of administration is not advised since loss of potency may result. If necessary, splitting should be done cleanly without crushing."

 
In the name-brand Wellbutrin SR, the sustained-release quality is in the binder, the glue that holds the tablet together. Generic versions (which would be called bupropion SR, not Wellbutrin SR) may be made differently. Contact the manufacturer to find out exactly how the tablet is formulated, or talk to a pharmacist specializing in psychopharmacology.
 
I personally found you CAN cut Wellbutrin SR (sustained release) tablets up -- the timed-release mechanism is mixed in with the drug. Put the pieces in a water-tight container and use them up within 24 hours because the time-release binder can absorb humidity and degrade.

For a short time, I cut up generic 100mg bupropion SR and took 50mg in the morning, Wellbutrin XL 150mg a couple of hours later, and another SR 50mg in the early evening for a total of 250mg/day. (I never tolerated Wellbutrin very well.)

To taper, convert your dosage to 100mg SR tablets, cut up the 100mg tablets, make reductions by 25mg or less, take 2 times a day.
 
(Note: If you cut an SR tablet in very small fragments or crush it, it won't to continue to be sustained-release -- the binder is extensively damaged. Take as though it was immediate-release.)

 

See: Tips for tapering off Wellbutrin, SR, XR, XL (buproprion)

 

Petunia.

I'm not a doctor.  My comments are not medical advise. These are my opinions based on my own experience and what I've learned. Please discuss your situation with a medical practitioner who has knowledge of tapering and withdrawal...if you are lucky enough to find one.

My Introduction Thread

Full Drug and Withdrawal History

Brief Summary

Several SSRIs for 13 years starting 1997 (for mild to moderate partly situational anxiety) Xanax PRN ~ Various other drugs over the years for side effects

2 month 'taper' off Lexapro 2010

Short acute withdrawal, followed by 2 -3 months of improvement then delayed protracted withdrawal

DX ADHD followed by several years of stimulants and other drugs trying to manage increasing symptoms

Failed reinstatement of Lexapro and trial of Prozac (became suicidal)

May 2013 Found SA, learned about withdrawal, stopped taking drugs...healing begins.

Protracted withdrawal, with a very sensitized nervous system, slowly recovering as time passes

Supplements which have helped: Vitamin C, Magnesium, Taurine

Bad reactions: Many supplements but mostly fish oil and Vitamin D

June 2016 - Started daily juicing, mostly vegetables and lots of greens.

Aug 2016 - Oct 2016 Best window ever, felt almost completely recovered

Oct 2016 -Symptoms returned - bad days and less bad days.

April 2018 - No windows, but significant improvement, it feels like permanent full recovery is close.

VIDEO: Where did the chemical imbalance theory come from?



VIDEO: How are psychiatric diagnoses made?



VIDEO: Why do psychiatric drugs have withdrawal syndromes?



VIDEO: Can psychiatric drugs cause long-lasting negative effects?

VIDEO: Dr. Claire Weekes

 

 

 

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For reducing the wellbutrin 100 SR by 25% every 3-4 days till I am down to zero in 2 weeks which is how long I have been taking it. I didn't grasp the concept number-wise. I imagine I reduce first by a quarter of the pill-25mg, then 4 days later 50mg, then 4 days later 75 mg then 100mg for 4 days is that correct? Isn't that slowly increasing the dose not reducing it Petunia?

W.

I have withdrawn myself off of many medications with and/or without doctor including seroquel,invega,zyprexa,paxil,

depakote,effexor,zoloft,mirtazapine etc.

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So yes I started your suggested taper of the Wellbutrin SR 100mg by 25% today by reducing the 100mg SR into 4 quarters and taking 75 mg for 4 days, then taking 50mg for three days then 25mg for three days. So ignore my last post. Just on the 25 mg after 3 days should I just come off it completely or cut the 25mg in half and take 12.5 mg for three days?

W.

I have withdrawn myself off of many medications with and/or without doctor including seroquel,invega,zyprexa,paxil,

depakote,effexor,zoloft,mirtazapine etc.

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  • Moderator Emeritus

Hello Wellbutrin,

 

I have merged a thread you started with the above question for Petunia with your original thread. We have one thread per member policy here. So you put all your questions here and everybody will see them.

 

The way I understood the suggestion Petunia made is like this: take 25 mg off the pill for 4 days (that will leave you with taking 75 mg), then take 50 mg off (which will leave you with 50 mg), after 4 days take 75 mg off (you will be taking 25 mg then) and after another 4 days you take nothing.

 

Hope this clarifies things for you ;)

 

Bubble 

Current: 9/2022 Xanax 0.08, Lexapro 2

2020 Xanax 0.26 (down from 2 mg in 2013), Lexapro 2.85 mg (down from 5 mg 2013)

Amitriptyline (tricyclic AD) and clonazepam for 3 months to treat headache in 1996 
1999. - present Xanax prn up to 3 mg.
2000-2005 Prozac CT twice, 2005-2010 Zoloft CT 3 times, 2010-2013 Escitalopram 10 mg
went from 2.5 to zero on 7 Aug 2013, bad crash 40 days after
reinstated to 5 mg Escitalopram 4Oct 2013 and holding liquid Xanax every 5 hours
28 Jan 2014 Xanax 1.9, 18 Apr  2015 1 mg,  25 June 2015 Lex 4.8, 6 Aug Lexapro 4.6, 1 Jan 2016 0.64  Xanax     9 month hold

24 Sept 2016 4.5 Lex, 17 Oct 4.4 Lex (Nov 0.63 Xanax, Dec 0.625 Xanax), 1 Jan 2017 4.3 Lex, 24 Jan 4.2, 5 Feb 4.1, 24 Mar 4 mg, 10 Apr 3.9 mg, May 3.85, June 3.8, July 3.75, 22 July 3.7, 15 Aug 3.65, 17 Sept 3.6, 1 Jan 2018 3.55, 19 Jan 3.5, 16 Mar 3.4, 14 Apr 3.3, 23 May 3.2, 16 June 3.15, 15 Jul 3.1, 31 Jul 3, 21 Aug 2.9 26 Sept 2.85, 14 Nov Xan 0.61, 1 Dec 0.59, 19 Dec 0.58, 4 Jan 0.565, 6 Feb 0.55, 20 Feb 0.535, 1 Mar 0.505, 10 Mar 0.475, 14 Mar 0.45, 4 Apr 0.415, 13 Apr 0.37, 21 Apr 0.33, 29 Apr 0.29, 10 May 0.27, 17 May 0.25, 28 May 0.22, 19 June 0.22, 21 Jun updose to 0.24, 24 Jun updose to 0.26

Supplements: Omega 3 + Vit E, Vit C, D, magnesium, Taurine, probiotic 

I'm not a medical professional. Any advice I give is based on my own experience and reading. 

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  • Moderator Emeritus

You started another thread just as I was typing...

 

So once again, please put all your questions in this thread.

 

You understood it correctly. If you don't feel any particular symptoms, i woudl stop taking 25 mg after 2 weeks. But let's wait till then and reassess if necessary.

 

Also,

 

 Please put your withdrawal history in your signature

Bubble

Current: 9/2022 Xanax 0.08, Lexapro 2

2020 Xanax 0.26 (down from 2 mg in 2013), Lexapro 2.85 mg (down from 5 mg 2013)

Amitriptyline (tricyclic AD) and clonazepam for 3 months to treat headache in 1996 
1999. - present Xanax prn up to 3 mg.
2000-2005 Prozac CT twice, 2005-2010 Zoloft CT 3 times, 2010-2013 Escitalopram 10 mg
went from 2.5 to zero on 7 Aug 2013, bad crash 40 days after
reinstated to 5 mg Escitalopram 4Oct 2013 and holding liquid Xanax every 5 hours
28 Jan 2014 Xanax 1.9, 18 Apr  2015 1 mg,  25 June 2015 Lex 4.8, 6 Aug Lexapro 4.6, 1 Jan 2016 0.64  Xanax     9 month hold

24 Sept 2016 4.5 Lex, 17 Oct 4.4 Lex (Nov 0.63 Xanax, Dec 0.625 Xanax), 1 Jan 2017 4.3 Lex, 24 Jan 4.2, 5 Feb 4.1, 24 Mar 4 mg, 10 Apr 3.9 mg, May 3.85, June 3.8, July 3.75, 22 July 3.7, 15 Aug 3.65, 17 Sept 3.6, 1 Jan 2018 3.55, 19 Jan 3.5, 16 Mar 3.4, 14 Apr 3.3, 23 May 3.2, 16 June 3.15, 15 Jul 3.1, 31 Jul 3, 21 Aug 2.9 26 Sept 2.85, 14 Nov Xan 0.61, 1 Dec 0.59, 19 Dec 0.58, 4 Jan 0.565, 6 Feb 0.55, 20 Feb 0.535, 1 Mar 0.505, 10 Mar 0.475, 14 Mar 0.45, 4 Apr 0.415, 13 Apr 0.37, 21 Apr 0.33, 29 Apr 0.29, 10 May 0.27, 17 May 0.25, 28 May 0.22, 19 June 0.22, 21 Jun updose to 0.24, 24 Jun updose to 0.26

Supplements: Omega 3 + Vit E, Vit C, D, magnesium, Taurine, probiotic 

I'm not a medical professional. Any advice I give is based on my own experience and reading. 

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Thank you Bubbles for your help and Petunia too. I will add my recent withdrawal history with my signature. I am just trying to figure that out as I am new here.Sorry for any inconvenience.

W.

I have withdrawn myself off of many medications with and/or without doctor including seroquel,invega,zyprexa,paxil,

depakote,effexor,zoloft,mirtazapine etc.

Link to comment
  • Moderator Emeritus

No problem. You are getting there ;)

Current: 9/2022 Xanax 0.08, Lexapro 2

2020 Xanax 0.26 (down from 2 mg in 2013), Lexapro 2.85 mg (down from 5 mg 2013)

Amitriptyline (tricyclic AD) and clonazepam for 3 months to treat headache in 1996 
1999. - present Xanax prn up to 3 mg.
2000-2005 Prozac CT twice, 2005-2010 Zoloft CT 3 times, 2010-2013 Escitalopram 10 mg
went from 2.5 to zero on 7 Aug 2013, bad crash 40 days after
reinstated to 5 mg Escitalopram 4Oct 2013 and holding liquid Xanax every 5 hours
28 Jan 2014 Xanax 1.9, 18 Apr  2015 1 mg,  25 June 2015 Lex 4.8, 6 Aug Lexapro 4.6, 1 Jan 2016 0.64  Xanax     9 month hold

24 Sept 2016 4.5 Lex, 17 Oct 4.4 Lex (Nov 0.63 Xanax, Dec 0.625 Xanax), 1 Jan 2017 4.3 Lex, 24 Jan 4.2, 5 Feb 4.1, 24 Mar 4 mg, 10 Apr 3.9 mg, May 3.85, June 3.8, July 3.75, 22 July 3.7, 15 Aug 3.65, 17 Sept 3.6, 1 Jan 2018 3.55, 19 Jan 3.5, 16 Mar 3.4, 14 Apr 3.3, 23 May 3.2, 16 June 3.15, 15 Jul 3.1, 31 Jul 3, 21 Aug 2.9 26 Sept 2.85, 14 Nov Xan 0.61, 1 Dec 0.59, 19 Dec 0.58, 4 Jan 0.565, 6 Feb 0.55, 20 Feb 0.535, 1 Mar 0.505, 10 Mar 0.475, 14 Mar 0.45, 4 Apr 0.415, 13 Apr 0.37, 21 Apr 0.33, 29 Apr 0.29, 10 May 0.27, 17 May 0.25, 28 May 0.22, 19 June 0.22, 21 Jun updose to 0.24, 24 Jun updose to 0.26

Supplements: Omega 3 + Vit E, Vit C, D, magnesium, Taurine, probiotic 

I'm not a medical professional. Any advice I give is based on my own experience and reading. 

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Hi everyone. Thank you Bubbles and Petunia for all your help. I am trying to understand and find the method for adding my signature and withdrawal history. I can't find any arrows beside my name on my posts that will lead me to settings so I can add signature and withdrawal history. I am hoping someone can help. I am glad to be here. The answers to my posts have been very helpful. Thanks :-)

W.

I have withdrawn myself off of many medications with and/or without doctor including seroquel,invega,zyprexa,paxil,

depakote,effexor,zoloft,mirtazapine etc.

Link to comment
  • Moderator Emeritus

Oh no! Here we go again: this must be the third time that I've had to merge your posts today.... So please: don't start new therads any more. Put ALL your questions here.

 

You have to click on your name which will take you to your profile. In the top right corner you will see a box with Edit my profile. Click on it and a new window will open with a drop down menu on the left. Click on Signature and fill it in. Click Save once you've finished.

Current: 9/2022 Xanax 0.08, Lexapro 2

2020 Xanax 0.26 (down from 2 mg in 2013), Lexapro 2.85 mg (down from 5 mg 2013)

Amitriptyline (tricyclic AD) and clonazepam for 3 months to treat headache in 1996 
1999. - present Xanax prn up to 3 mg.
2000-2005 Prozac CT twice, 2005-2010 Zoloft CT 3 times, 2010-2013 Escitalopram 10 mg
went from 2.5 to zero on 7 Aug 2013, bad crash 40 days after
reinstated to 5 mg Escitalopram 4Oct 2013 and holding liquid Xanax every 5 hours
28 Jan 2014 Xanax 1.9, 18 Apr  2015 1 mg,  25 June 2015 Lex 4.8, 6 Aug Lexapro 4.6, 1 Jan 2016 0.64  Xanax     9 month hold

24 Sept 2016 4.5 Lex, 17 Oct 4.4 Lex (Nov 0.63 Xanax, Dec 0.625 Xanax), 1 Jan 2017 4.3 Lex, 24 Jan 4.2, 5 Feb 4.1, 24 Mar 4 mg, 10 Apr 3.9 mg, May 3.85, June 3.8, July 3.75, 22 July 3.7, 15 Aug 3.65, 17 Sept 3.6, 1 Jan 2018 3.55, 19 Jan 3.5, 16 Mar 3.4, 14 Apr 3.3, 23 May 3.2, 16 June 3.15, 15 Jul 3.1, 31 Jul 3, 21 Aug 2.9 26 Sept 2.85, 14 Nov Xan 0.61, 1 Dec 0.59, 19 Dec 0.58, 4 Jan 0.565, 6 Feb 0.55, 20 Feb 0.535, 1 Mar 0.505, 10 Mar 0.475, 14 Mar 0.45, 4 Apr 0.415, 13 Apr 0.37, 21 Apr 0.33, 29 Apr 0.29, 10 May 0.27, 17 May 0.25, 28 May 0.22, 19 June 0.22, 21 Jun updose to 0.24, 24 Jun updose to 0.26

Supplements: Omega 3 + Vit E, Vit C, D, magnesium, Taurine, probiotic 

I'm not a medical professional. Any advice I give is based on my own experience and reading. 

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Is it possible to edit history which is confidential on community stats. I made some typos, etc.

W.

I have withdrawn myself off of many medications with and/or without doctor including seroquel,invega,zyprexa,paxil,

depakote,effexor,zoloft,mirtazapine etc.

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  • Administrator

No one but the staff can see your confidential history. Do not worry about typos.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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I have been withdrawing from the Wellbutrim SR 100 as per Petunia's wonderful instruction which were 75 mg for three days,50mg for three days and then 25mg for three days and then off completely. I am on my second day of 50mg. However I am having a lot of trouble sleeping which I had when taking the full dose anyway.But it

But it seems to be worsening. Should I accelerate the withdrawal and go to

25mg tomorrow which was supposed to be

my third day on 50mg and then resume

tapering off the 25mg normally?

W.

I have withdrawn myself off of many medications with and/or without doctor including seroquel,invega,zyprexa,paxil,

depakote,effexor,zoloft,mirtazapine etc.

Link to comment
  • Moderator Emeritus

When we experience increase in symptoms, it usually means we are going too fast and our CNS is not happy with the removal of the drug... This usually means we should slow down, stop and wait for the symptoms to go away before continuing the taper. Maybe your brain is too sensitised from all your previous withdrawals and although you have been on Well. for a short time it still finds it hard to cope with its absence...

 

Do you have any other symptoms except for insomnia?

Current: 9/2022 Xanax 0.08, Lexapro 2

2020 Xanax 0.26 (down from 2 mg in 2013), Lexapro 2.85 mg (down from 5 mg 2013)

Amitriptyline (tricyclic AD) and clonazepam for 3 months to treat headache in 1996 
1999. - present Xanax prn up to 3 mg.
2000-2005 Prozac CT twice, 2005-2010 Zoloft CT 3 times, 2010-2013 Escitalopram 10 mg
went from 2.5 to zero on 7 Aug 2013, bad crash 40 days after
reinstated to 5 mg Escitalopram 4Oct 2013 and holding liquid Xanax every 5 hours
28 Jan 2014 Xanax 1.9, 18 Apr  2015 1 mg,  25 June 2015 Lex 4.8, 6 Aug Lexapro 4.6, 1 Jan 2016 0.64  Xanax     9 month hold

24 Sept 2016 4.5 Lex, 17 Oct 4.4 Lex (Nov 0.63 Xanax, Dec 0.625 Xanax), 1 Jan 2017 4.3 Lex, 24 Jan 4.2, 5 Feb 4.1, 24 Mar 4 mg, 10 Apr 3.9 mg, May 3.85, June 3.8, July 3.75, 22 July 3.7, 15 Aug 3.65, 17 Sept 3.6, 1 Jan 2018 3.55, 19 Jan 3.5, 16 Mar 3.4, 14 Apr 3.3, 23 May 3.2, 16 June 3.15, 15 Jul 3.1, 31 Jul 3, 21 Aug 2.9 26 Sept 2.85, 14 Nov Xan 0.61, 1 Dec 0.59, 19 Dec 0.58, 4 Jan 0.565, 6 Feb 0.55, 20 Feb 0.535, 1 Mar 0.505, 10 Mar 0.475, 14 Mar 0.45, 4 Apr 0.415, 13 Apr 0.37, 21 Apr 0.33, 29 Apr 0.29, 10 May 0.27, 17 May 0.25, 28 May 0.22, 19 June 0.22, 21 Jun updose to 0.24, 24 Jun updose to 0.26

Supplements: Omega 3 + Vit E, Vit C, D, magnesium, Taurine, probiotic 

I'm not a medical professional. Any advice I give is based on my own experience and reading. 

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No just the insomnia.I was restless as

well last night before bed. I had insomnia practically the whole time on Wellbutrin so I am eager to get it out of my system. Thinking of going on 25mg tomorrow instead of 50mg. That would have been my last day or third day on 50 mg.

By the way Bubbles and everyone thank you for your help. I really appreciate it. I am sorry when I was just learning how to use the site that I started 3 new threads. I know now to only post here as I have been doing. Cheers.:-)

W.

I have withdrawn myself off of many medications with and/or without doctor including seroquel,invega,zyprexa,paxil,

depakote,effexor,zoloft,mirtazapine etc.

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  • Administrator

I would hold for a day or so -- and reduce every 4 days at the fastest.

 

Don't go from 100mg to 50mg, it's too big of a decrease.

 

When you are down to 25mg, plan to reduce by 25% of 25mg for each decrease.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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