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More about how light stimulation affects our body clocks


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http://www.nytimes.com/2012/02/21/health/aging-of-eyes-is-blamed-in-circadian-rhythm-disturbances.html?_r=1

 

While this article is about problems of aging, it contains good clues for those of us who are either hypersensitive to light or have withdrawal insomnia, such as:

 

- Make sure to shut off lights in the evening. A little light can tell your suprachiasmatic nucleus (SCN) to wake up rather than go to sleep.

 

- Our hunches about blue-blocking sunglasses are probably correct. They probably are more soothing to our sensitive nervous systems than regular sunglasses.

 

- Getting good light in the daytime can help reset the circadian rhythm. If you're not getting out much, you may want to get a lightbox.

 

- Sitting at the computer can be like sitting in front of a lightbox. If your sleep is poor, get off the computer by dusk and turn lights down and off to make sure your SCN gets the message to make melatonin.

 

Aging of Eyes Is Blamed for Range of Health Woes

By LAURIE TARKAN NYTimes.com February 20, 2012

 

THE HYPOTHESIS

 

The aging eye filters out blue light, affecting circadian rhythm and health in older adults.

 

THE INVESTIGATORS

 

Dr. Martin Mainster and Dr. Patricia Turner, University of Kansas School of Medicine.

 

For decades, scientists have looked for explanations as to why certain conditions occur with age, among them memory loss, slower reaction time, insomnia and even depression. They have scrupulously investigated such suspects as high cholesterol, obesity, heart disease and an inactive lifestyle.

 

Now a fascinating body of research supports a largely unrecognized culprit: the aging of the eye.

 

The gradual yellowing of the lens and the narrowing of the pupil that occur with age disturb the body’s circadian rhythm, contributing to a range of health problems, these studies suggest. As the eyes age, less and less sunlight gets through the lens to reach key cells in the retina that regulate the body’s circadian rhythm, its internal clock.

 

“We believe the effect is huge and that it’s just beginning to be recognized as a problem,” said Dr. Patricia Turner, an ophthalmologist in Leawood, Kan., who with her husband, Dr. Martin Mainster, a professor of ophthalmology at the University of Kansas Medical School, has written extensively about the effects of the aging eye on health.

 

Circadian rhythms are the cyclical hormonal and physiological processes that rally the body in the morning to tackle the day’s demands and slow it down at night, allowing the body to rest and repair. This internal clock relies on light to function properly, and studies have found that people whose circadian rhythms are out of sync, like shift workers, are at greater risk for a number of ailments, including insomnia, heart disease and cancer.

 

“Evolution has built this beautiful timekeeping mechanism, but the clock is not absolutely perfect and needs to be nudged every day,” said Dr. David Berson, whose lab at Brown University studies how the eye communicates with the brain.

 

So-called photoreceptive cells in the retina absorb sunlight and transmit messages to a part of the brain called the suprachiasmatic nucleus (S.C.N.), which governs the internal clock. The S.C.N. adjusts the body to the environment by initiating the release of the hormone melatonin in the evening and cortisol in the morning.

 

Melatonin is thought to have many health-promoting functions, and studies have shown that people with low melatonin secretion, a marker for a dysfunctional S.C.N., have a higher incidence of many illnesses, including cancer, diabetes and heart disease.

 

It was not until 2002 that the eye’s role in synchronizing the circadian rhythm became clear. It was always believed that the well-known rods and cones, which provide conscious vision, were the eye’s only photoreceptors. But Dr. Berson’s team discovered that cells in the inner retina, called retinal ganglion cells, also had photoreceptors and that these cells communicated more directly with the brain.

 

These vital cells, it turns out, are especially responsive to the blue part of the light spectrum. Among other implications, that discovery has raised questions about our exposure to energy-efficient light bulbs and electronic gadgets, which largely emit blue light.

 

But blue light also is the part of the spectrum filtered by the eye’s aging lens. In a study published in The British Journal of Ophthalmology, Dr. Mainster and Dr. Turner estimated that by age 45, the photoreceptors of the average adult receive just 50 percent of the light needed to fully stimulate the circadian system. By age 55, it dips to 37 percent, and by age 75, to a mere 17 percent.

 

“Anything that affects the intensity of light or the wavelength can have important consequences for the synchronization of the circadian rhythm, and that can have effects on all types of physiological processes,” Dr. Berson said.

 

Several studies, most in European countries, have shown that the effects are not just theoretical. One study, published in the journal Experimental Gerontology, compared how quickly exposure to bright light suppresses melatonin in women in their 20s versus in women in their 50s. The amount of blue light that significantly suppressed melatonin in the younger women had absolutely no effect on melatonin in the older women....

 

Another study, published in The Journal of Biological Rhythms, found that after exposure to blue light, younger subjects had increased alertness, decreased sleepiness and improved mood, whereas older subjects felt none of these effects.

 

Researchers in Sweden studied patients who had cataract surgery to remove their clouded lenses and implant clear intraocular lenses. They found that the incidence of insomnia and daytime sleepiness was significantly reduced. Another study found improved reaction time after cataract surgery.

 

....

That is why Dr. Mainster and Dr. Turner question a practice common in cataract surgery. About one-third of the intraocular lenses implanted worldwide are blue-blocking lenses, intended to reduce the risk of macular degeneration by limiting exposure to potentially damaging light.

 

But there is no good evidence showing that people who have cataract surgery are at greater risk of macular degeneration. And evidence of the body’s need for blue light is increasing, some experts say.

 

You can always wear sunglasses if you’re in a brilliant environment that’s uncomfortable. You can remove those sunglasses for optimal circadian function, but you can’t take out the filters if they’re permanently implanted in your eyes,” Dr. Mainster said.

 

Because of these light-filtering changes, Dr. Mainster and Dr. Turner believe that with age, people should make an effort to expose themselves to bright sunlight or bright indoor lighting when they cannot get outdoors. Older adults are at particular risk, because they spend more time indoors.

 

“In modern society, most of the time we live in a controlled environment under artificial lights, which are 1,000 to 10,000 times dimmer than sunlight and the wrong part of the spectrum,” Dr. Turner said.

 

In their own offices, Dr. Mainster and Dr. Turner have installed skylights and extra fluorescent lights to help offset the aging of their own eyes.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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  • 5 months later...
  • Moderator Emeritus

"A study done with hamsters at Ohio State University Medical Center has found that chronic exposure to dim light at night can cause signs of depression after just a few weeks. The study also showed changes in the hamsters’ hippocampus similar to brain changes seen in depressed people. They pointed out that rates of depression have risen along with exposure to artificial light at night:

 

“Exposure to artificial light at night (LAN) has surged in prevalence during the past 50 years, coinciding with rising rates of depression.”

 

Full article: http://articles.mercola.com/sites/articles/archive/2012/08/09/too-much-night-light-causes-depression.aspx?e_cid=20120809_DNL_artNew_2

Psychotropic drug history: Pristiq 50 mg. (mid-September 2010 through February 2011), Remeron (mid-September 2010 through January 2011), Lexapro 10 mg. (mid-February 2011 through mid-December 2011), Lorazepam (Ativan) 1 mg. as needed mid-September 2010 through early March 2012

"Never attribute to malice that which is adequately explained by stupidity." -Hanlon's Razor


Introduction: http://survivingantidepressants.org/index.php?/topic/1588-introducing-jemima/

 

Success Story: http://survivingantidepressants.org/index.php?/topic/6263-success-jemima-survives-lexapro-and-dr-dickhead-too/

Please note that I am not a medical professional and my advice is based on personal experience, reading, and anecdotal information posted by other sufferers.

 

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Barbarannamated

I wonder how electronic readers (Nook, etc) are impacting this..

Pristiq tapered over 8 months ending Spring 2011 after 18 years of polydrugging that began w/Zoloft for fatigue/general malaise (not mood). CURRENT: 1mg Klonopin qhs (SSRI bruxism), 75mg trazodone qhs, various hormonesLitigation for 11 years for Work-related injury, settled 2004. Involuntary medical retirement in 2001 (age 39). 2012 - brain MRI showing diffuse, chronic cerebrovascular damage/demyelination possibly vasculitis/cerebritis. Dx w/autoimmune polyendocrine failure.<p>2013 - Dx w/CNS Sjogren's Lupus (FANA antibodies first appeared in 1997 but missed by doc).

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I wonder how electronic readers (Nook, etc) are impacting this..

 

Barbara

 

Personally, I have just recently discovered that the light from my tablet at night is what has often kept me awake = insomnia!

I used to use my tablet for the internet and for Kobo reading at night and the bright light is problematic for me. Even using the Kobo with "night time reading lighting" is too bright for my eyes... also not watching TV in the bedroom anymore before sleep. I much better sleep now.

I think! Too much!

Jan. 2009 150 mg. Venlafaxine

2012

5 June 112.5 mg. Venflx

25 June 75 mg. Venflx

8 July Fluox 5ML (0 Venflx)[/b]

10 July aprox. 20 mg Fluoxetine liquid, trouble measuring between 4 - 5 ml, 0 Venflx.

15 July Fluox 5 ML + Vnflx. 10 - 6 grains

24 July Fluox 5ML + 37.5 mg Venflx.

10 Aug Fluox 4.5 ML

13 Aug.Fluox 18 mg liquid; 18 Aug. Fluox 17 mg; 25 Aug. Fluox 16 mg;

2 Sept Fluox 15 mg; 10 Sept Fluox 14 mg; 17 Sept. Fluox 13.6 mg; 29 Sept. Fluox 13 mg.

7 Oct. Fluox 12 mg; 14 Oct. Fluox 11 mg; 21 Oct; Fluox 10 mg; 23 Oct. 9mg; 26 Oct. 8 mg.

21 Nov. 5 mg; 3 Nov. ZERO

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Barbarannamated

I suspect that happening frequently and people aren't making the connection (general population). More drugs to sell..

 

http://www.theipadfan.com/hidden-ipad-feature-insomnia/

Pristiq tapered over 8 months ending Spring 2011 after 18 years of polydrugging that began w/Zoloft for fatigue/general malaise (not mood). CURRENT: 1mg Klonopin qhs (SSRI bruxism), 75mg trazodone qhs, various hormonesLitigation for 11 years for Work-related injury, settled 2004. Involuntary medical retirement in 2001 (age 39). 2012 - brain MRI showing diffuse, chronic cerebrovascular damage/demyelination possibly vasculitis/cerebritis. Dx w/autoimmune polyendocrine failure.<p>2013 - Dx w/CNS Sjogren's Lupus (FANA antibodies first appeared in 1997 but missed by doc).

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  • 1 month later...
  • Administrator

Most of us with withdrawal sleeplessness need all the melatonin we can make!

 

Really? Using a Computer Before Bed Can Disrupt Sleep

By ANAHAD O'CONNOR

September 10, 2012, nytimes.com

 

In today’s gadget-obsessed world, sleep experts often say that for a better night’s rest, Americans should click the “off” buttons on their smartphones and tablets before tucking in for the night. Electronic devices stimulate brain activity, they say, disrupting your ability to drift off to sleep. But according to the National Sleep Foundation, more than 90 percent of Americans regularly use a computer or electronic device of some kind in the hour before bed.

 

Increasingly, researchers are finding that artificial light from some devices at night may tinker with brain chemicals that promote sleep. Researchers at Rensselaer Polytechnic Institute showed that exposure to light from computer tablets significantly lowered levels of the hormone melatonin, which regulates our internal clocks and plays a role in the sleep cycle.

 

In the study, published in the journal Applied Ergonomics, the researchers had volunteers read, play games and watch movies on an iPad, iPad 2 or PC tablet for various amounts of time while measuring the amount of light their eyes received. They found that two hours of exposure to a bright tablet screen at night reduced melatonin levels by about 22 percent.

 

....researchers say melatonin suppression may not only cause sleep disturbances, but also raise the risk of obesity, diabetes and other disorders.

 

To be on the safe side, the authors of the latest study suggest limiting computer use before bed, or at the very least dimming your screen as much as possible.

 

....

 

http://well.blogs.nytimes.com/2012/09/10/really-using-a-computer-before-bed-can-disrupt-sleep/

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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  • 2 years later...
  • Moderator Emeritus

Over the last month, thanks to the insistence of my 12 year old daughter, we have not been turning on lights/tv/computer in the evening.  We leave the curtains open overnight so we wake up gradually with the sun, and get sleepy gradually as the sun does too.  I initially thought I'd hate it and find it restricting, but I LOVE it.  It feels like goodness pouring into my body.  I'm falling asleep easier and quicker than I ever have in my life, and waking with more ease too - even when I wake with anxiety I feel contained in the natural cycle of the world and sun. 

 

Can't fully explain it, but I feel almost addicted to it now.  I get quite upset if someone flicks a light on and interrupts my flow and connection with the sun.  I think it's a regulating effect for me, and my body is lapping it up.  I used to not know when to get up in the morning.  Now I do.  It feels a beautiful thing to do for my body.  How ironic that for years I told my daughter 'no' because I thought it would be too weird. 

2010  Fluoxetine 20mg.  2011  Escitalopram 20mg.  2013 Tapered badly and destabilised CNS.  Effexor 150mg. 

2015 Begin using info at SurvivingAntidepressants.  Cut 10% - bad w/d 2 months, held 1 month. 

Micro-tapering: four weekly 0.4% cuts, hold 4 weeks (struggling with symptoms).

8 month hold.

2017 Micro-tapering: four weekly 1% cuts, hold 4 weeks (symptoms almost non-existent).

2020 Still micro-tapering. Just over 2/3 of the way off effexor. Minimal symptoms, - and sleeping well.
Supplements: Fish oil, vitamin C, iron, oat-straw tea, nettle tea.

My story of healing:ContinuedHealing

***I am not a doctor; please do your own research and be able to take responsibility for decisions you make.*** 

           'The possibility of renewal exists so long as life exists.'  Dr Gabor Mate.

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