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Zakalwe: single dose Lexapro


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Hello everyone,

I took a single dose of lexapro early June 2018.  I've had some form of PSSD since then.  Strangely enough, I also got middle of the night insomnia starting about 6 weeks after the dose.  I never had these symptoms before I took that single dose.  I never thought that PSSD would become a distant secondary concern but the insomnia is kicking my a**.  I sleep for 3 hours and then I wake up.  Then I wake up almost every hour after that.  Before I took lexapro, if I had a bad night's sleep I would make it up the next day.  I've had this consistent insomnia for about 3 weeks now. 



single dose lexapro early June 2018

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  • ChessieCat changed the title to Zakalwe: single dose Lexapro
  • Moderator Emeritus

Hi Zakalwe, welcome to SA. I am sorry that you had such a bad reaction to just one dose of lexapro, sadly that happens quite a lot. 

You will recover but it takes time.  I will get some links for you that might help. I am sorry I can't say very much, it is 2.30am and way past my bedtime! 

Insomnia is one of the worst symptoms of an unstable nervous system, and you need to have really good sleep hygeine. No screens for an hour or 2 before bed. (Definitely well before 2.30am, don't follow my example! ). 

There are many topics here about symptoms and sleep problems with some great suggestions. I am a chronic insomniac and found them really helpful.

Symptoms and sleep


We have a PSSD forum where people discuss this problem, but please be aware that this is a family site so be careful with descriptions of symptoms. We have some very old and very young members so do not post anything you wouldn't want your gran or your young sister/brother to see! 




We ask all our members to fill in their signature with their drug and tapering history, include any that you have taken in the past. 



**I am not a medical professional, if in doubt please consult a doctor with withdrawal knowledge.



Different drugs occasionally (mostly benzos) 1976 - 1981 (no problem)

1993 - 2002 in and out of hospital. every type of drug + ECT. Staring with seroxat

2002  effexor. 

Tapered  March 2012 to March 2013, ending with 5 beads.

Withdrawal April 2013 . Reinstated 5 beads reduced to 4 beads May 2013

Restarted taper  Nov 2013  

OFF EFFEXOR Feb 2015    :D 

Tapered atenolol and omeprazole Dec 2013 - May 2014


Tapering tramadol, Feb 2015 100mg , March 2015 50mg  

 July 2017 30mg.  May 15 2018 25mg

Taking fish oil, magnesium, B12, folic acid, bilberry eyebright for eye pressure. 


My story http://survivingantidepressants.org/index.php?/topic/4199-hello-mammap-checking-in/page-33


Lesson learned, slow down taper at lower doses. Taper no more than 10% of CURRENT dose if possible



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