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anytriptaline

Taking a cholinergic agonist to fight anti-cholinergic effects of TCAs?

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anytriptaline

I'm about to start a slow tapering from amitriptyline after over a decade of use for sleep issues

 

However, the side effects are making being productive virtually impossible, I'm beyond sedated at the moment and I need to be able to hold a full time job and drive a car

 

A doctor I visited claimed all of my issues (and benefits) probably arise from the anticholinergic side effects

 

I've been researching about Bethanechol, a cholinergic agonist that is sometimes used with geriatric patients taking tricyclics .

 

Does anyone have any experience or knowledge about such a combination? Could it cause more harm than good?

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Altostrata

Read this:

 

 

After decades of experience with SSRI withdrawal, it is now quite clear that "cholinergic rebound" does not explain all antidepressant withdrawal symptoms, not even in TCAs.

 

If withdrawal syndrome from TCAs was not solved with cholinergic agonists 30 years ago, they're not the solution now. 

 

As a peer support group, we are not in a position to advise on new drug prescriptions. If you would like to experiment with Bethanechol or other cholinergic agonist, please let us know what happens.

 

See https://www.drugs.com/pro/bethanechol.html

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anytriptaline

Yeah, but my problems at the moment have nothing to do with withdrawal, it's more like, the meds are working too damn good, they not only make me sleep at night, they keep me asleep all day!

 

I'll talk with my doctor next week, if I hop into them I'll report about it

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Altostrata

Please put questions about your personal situation in your Intro topic, we need the context there to answer them.

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