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omeprazole and lexparo tapering


Sicksagittarius
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Hi there! Has anyone had experience trying to taper of the PPI omeprazole (40 mg) since March (5 months) while weaning off of SSRI lexapro? I've been on 2.5 mg of lexapro since April after weaning off way too fast and having extreme withdrawal symptoms. I found research stating these two specific drugs together can double the amount of lexapro in system. I'm scared I really have 5 mg worth in my system and if I try to wean off of omeprazole I'll go into withdrawal symptoms. Can I prepare my body in any way before trying to lower it? I have a histamine intolerance, SIBO, leaky gut, PCOS, C diff, and lots of other bacterial overgrowth and its extremely important I get off so I can absorb more nutrients. I am getting back to being strict with my diet of no gluten, dairy, soy, antiinflammatory, low fodmap, GAPS, low histamine, etc. 

-2014: Lexapro/escitalopram 10 mg, 2015-2021: Lexapro/escitalopram 20 mg

-10/2020-3/2021: decreased 20 mg to 15 mg, 1 mg a month

-4/2021: decreased to 10 mg, held for 11 days, 4/2021: decreased to 5 mg, held for 8 days

-4/2021: 3-6 days cold turkey lexapro, withdrawal symptoms so reinstated 2.5 mg 

-omeprazole taper: 9/2021 cut 25%, 10/20/21 25% cut, 12/1/21 25%, 12/28/21 25% cut, (9/36 beads of 40 mg)

-11/2020 omeprazole 20 mg, 3/2021: omeprazole 40 mg,

-Nordic Naturals Ultimate omega 3 fish pill: 1280 mg

-montelukast: 10 mg dailyzyrtec: 10 mg daily 

-3/20/2021-7/25: mesalamine 1.2 GM, 3 times a day - dropped

-birth control: Trilinyah 2014- 2/1/2021 quit cold turkey middle of pack 

7/16/2021-8/1/2021 Quicksilver Liposomal multivitamin liquid: biotin, zinc, Vitamins A, C, D E, K, Niacin,, Thiomine, Riboflavin,Vitamin B6, B12, 7/16/2021- 8/25/2021 - boswelia complex (tumeric. ginger, celery) - 2 a day - dropped

7/16/2021 - probiophage probiotic - dropped 

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