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Blood pressure spikes? The tyramine connection


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Antidepressant withdrawal syndrome can bring with it hypersensitivity to certain foods, sometimes causing a rise in blood pressure after eating.

 

If you didn't have blood pressure problems before taking an antidepressant, this is part of your adverse reaction to it or withdrawal syndrome and your blood pressure will probably go back to normal over time.

 

If you notice this happening after you eat certain foods, it may be a reaction to tyramine, see http://www.mayoclinic.com/health/maois/HQ01575

 

Some foods high in tyramine include:

  • Aged cheeses
  • Cured meats, such as sausage, pepperoni and salami
  • Sauerkraut
  • Soy sauce
  • Yeast-extract spreads, such as Marmite
  • Improperly stored or spoiled foods
  • Broad bean (fava bean) pods
  • Banana peels
  • Tap (draft) beer or unpasteurized beer
  • Some wines

MAOIs are a type of antidepressant that affect monoamines. People taking MAOIs become sensitive to tyramine and follow a special diet excluding it.

 

Antidepressants such as escilatopram, paroxetine, and venlafaxine also affect monoamines (serotonin). Many people suffering from withdrawal syndrome become hypersensitive to tyramine as well.

 

If these foods are causing your blood pressure spikes, you may wish to avoid them for a while -- follow an MAOI diet -- and let your nervous system normalize.

 

(Also see Bad reaction to Chinese food?)

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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  • 2 years later...

I had high bp in with treated wd attempts to treat it too low bp. 

I am still dealing with this today.. including reactions to bp drugs I can't seem to find one I can tolerate. I have not noticed a connection to food and bp spikes but I was not looking either. So I will keep an eye out for this connection. 

My last apt with the kidney specialist my bp swung from high to low while I was there.. causing her to move me from room to room accessing different equipment to test me on. I told her about my reactions to bp meds and she is recommending my doc not treat me.. so she said to me at least. No cause was given at that apt but I will bet some sort of psych cause will be identified.. as usual... anxiety is one of the usual ones for bp spikes. I know this already. 

 

Today I was reminded of this again by reading a pm I wrote here.. I tend to forget things. I went looking for what could cause these spikes what I learned was that swings from high to low in bp is more predictive of stroke then high bp. 

Before you say magnesium to me I react badly to mag too.. last attempt to take a normal dose had me on the couch and barely moving for the wkend.. which was the wkend I watched breaking bad... marathon I had not heard of the show till then... it will always be connected to magnesium for me. 

 

This article about swings in bp talks of different drugs better able to treat it but does not name names. 

http://www.telegraph.co.uk/news/health/news/7423151/Swings-in-blood-pressure-could-better-predict-stroke-than-high-average-readings.html

Variations in blood pressure were also important indicators of the risk of a heart attack, heart failure and chest pain, the findings show.

Experts from Oxford University, who carried out the research, called for treatment guidelines to be reviewed as such changes in blood pressure levels are currently ignored as irrelevant.

Prof Peter Rothwell, who led the study, said: “Previously, such fluctuations were considered to be benign and uninformative.

"We have shown that it is variations in people's blood pressure rather than the average level that predicts stroke most powerfully.

“Occasional high values, and what might be called episodic hypertension, carry a high risk of stroke.”

The research looked at how blood pressure variability affected stroke risk in four trials, each including more than 2,000 patients, all of whom had previously experienced a so-called "mini-stroke", or transient ischemic attack (TIA).that is me one from birth control another supposedly from lidocaine or just happened to happen the same time I had lidocaine. 

I had this in a more severe form in hard wd.. it seemed to level off some but did not go away. Not yet.

 

 

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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Suggested drugs to treat:

Two other studies, published in The Lancet and The Lancet Neurology, found that three groups of blood pressure drug, ACE inhibitors, angiotensin-2-receptor blockers and beta blockers, increased variation, while another two calcium channel blockers and non-loop diuretic drugs, reduced it.

http://www.telegraph.co.uk/news/health/news/7423151/Swings-in-blood-pressure-could-better-predict-stroke-than-high-average-readings.html

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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  • 6 years later...

This website continues to be amazing. I’m almost 5 years out from my attempt to get off Lexapro. I’m still on a very low dose (1.5 mg). I’m mostly fine. But one annoying thing is I get these heart palpitations after eating. I couldn’t figure it out. I kept a log of the foods and didn’t see a commonality - cheddar cheese, Parmesan cheese, tofu, deli meats, dried fruit -  duh! It’s tyramine! My whole diet is tyramine. I’m going to try low tyramine for a bit and see how that goes. 

16 years on SSRI's (Celexa, then Lexapro)

Tapered down over several years. Last dose November 2016 (2.5 mg)

Withdrawal symptoms began March 2017

Attempt to reinstate at 5mg in June 2017 led to worsening symptoms

Reinstated at .4 mg in July 2017 with beneficial results. 

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