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Pattycat: is vortioxetine / Trintellix / Brintellix soluble?


Pattycat

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Please use dates for the following info, thank you:

 

Last 2 years 2.5mg brintellix. Hoping to taper off.

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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On 10/7/2015 at 12:30 AM, erer said:

Make your own vortioxetine liquid

The active ingredient in the tablets, vortioxetine, is slightly soluble in water. This means you or a compounding pharmacy can make a liquid suspension from vortioxetine, see How to make a liquid from tablets or capsules

  • A liquid will be a suspension, not a consistent or "homeogenous" solution. 
  • Vortioxetine is highly soluble in ethanol and a substance called DMSO, as are many psycho-neuro-active prescription medications. Ethanol is readily available in vodka. You can get oral or medical grade DMSO from many sources. If you have questions about this, feel free to post them in this topic.

 

I've chatted with the other mods and they said that you can use a small amount of Vodka.  The following is how Rhiannon was originally dissolving her Celexa tablets.

 

On 5/2/2011 at 1:00 PM, Rhiannon said:

I use a shot glass and dissolve the tablet in a small amount of water (enough to cover it) and a couple of mLs of ethanol (very pure drinking alcohol, I use "Everclear" type, available at the liquor store.) The tablet doesn't dissolve quickly, so I usually leave it there and come back in about twenty minutes.

 

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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  • 2 years later...
  • Moderator Emeritus

@Pattycat

 

Hi, a member has you asked this question in the tips for tapering vortioxetine topic:

 

22 minutes ago, YachtRock said:

 

Your last post was 3 years ago, how are things now? Being at 2.5mg sounds like you were already on the right track!

 

 

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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