Caspur Posted September 10, 2019 Posted September 10, 2019 All, Public Health England has today published its report on prescribed drug dependence in the UK. The prescribed harm communities in the UK have been waiting a long time for this report. The Recommendations are encouraging. Lets hope they are implemented! The report and associated information and data can be found here: https://www.gov.uk/government/publications/prescribed-medicines-review-report Cheers Caspur 2011 - started Venlafaxine (again) at 75mg Raised to 150 mg at some point - unsure of dates. Reduced back down to 75 mg. Doctor advised this would be a lifetime, maintenance dose 2017 - Side effects now intolerable. Started taper from June 15th - 5% dose reduction steps (two 12 hourly doses). 2017 - October 20th - took last dose of Venlafaxine - 4 mg. Debilitating symptoms followed. 2017/18 - diazepam - 8mg/day for 1 month - 7 week taper Feb 2018 2017/18 - duloxetine - max 90mg - now stopped 2018 - Feb 25mg quetiapine, increased to 50mg. 2018 - March/April - increased venlafaxine slowly (10mg steps) to 75 mg/day. Recovery from withdrawal followed. 2018 - July 13 - stopped quetiapine after 2 month taper. Late July - had to reinstate quetiapine due to intolerable withdrawal. Now tapering from 25mg 2019 - June - stopped quetiapine after 10 month taper. Mild insomnia only symptom. 2021 - June - venlafaxine approx 6.0 mg see Taper history details
Caspur Posted September 10, 2019 Author Posted September 10, 2019 Not surprisingly, its already in the mainstream news: https://www.bbc.co.uk/news/health-49639914 Also with associated case studies: https://www.bbc.co.uk/news/uk-scotland-40442178 2011 - started Venlafaxine (again) at 75mg Raised to 150 mg at some point - unsure of dates. Reduced back down to 75 mg. Doctor advised this would be a lifetime, maintenance dose 2017 - Side effects now intolerable. Started taper from June 15th - 5% dose reduction steps (two 12 hourly doses). 2017 - October 20th - took last dose of Venlafaxine - 4 mg. Debilitating symptoms followed. 2017/18 - diazepam - 8mg/day for 1 month - 7 week taper Feb 2018 2017/18 - duloxetine - max 90mg - now stopped 2018 - Feb 25mg quetiapine, increased to 50mg. 2018 - March/April - increased venlafaxine slowly (10mg steps) to 75 mg/day. Recovery from withdrawal followed. 2018 - July 13 - stopped quetiapine after 2 month taper. Late July - had to reinstate quetiapine due to intolerable withdrawal. Now tapering from 25mg 2019 - June - stopped quetiapine after 10 month taper. Mild insomnia only symptom. 2021 - June - venlafaxine approx 6.0 mg see Taper history details
Caspur Posted September 10, 2019 Author Posted September 10, 2019 https://www.theguardian.com/uk-news/2019/sep/10/addictive-medication-nhs-opioid-crisis-government-study-england?CMP=Share_iOSApp_Other Theres some poor stuff in this article and antidepressants seem to be suggested as being 'separate' from other medications that cause dependence and withdrawal. 2011 - started Venlafaxine (again) at 75mg Raised to 150 mg at some point - unsure of dates. Reduced back down to 75 mg. Doctor advised this would be a lifetime, maintenance dose 2017 - Side effects now intolerable. Started taper from June 15th - 5% dose reduction steps (two 12 hourly doses). 2017 - October 20th - took last dose of Venlafaxine - 4 mg. Debilitating symptoms followed. 2017/18 - diazepam - 8mg/day for 1 month - 7 week taper Feb 2018 2017/18 - duloxetine - max 90mg - now stopped 2018 - Feb 25mg quetiapine, increased to 50mg. 2018 - March/April - increased venlafaxine slowly (10mg steps) to 75 mg/day. Recovery from withdrawal followed. 2018 - July 13 - stopped quetiapine after 2 month taper. Late July - had to reinstate quetiapine due to intolerable withdrawal. Now tapering from 25mg 2019 - June - stopped quetiapine after 10 month taper. Mild insomnia only symptom. 2021 - June - venlafaxine approx 6.0 mg see Taper history details
Nelly Posted September 10, 2019 Posted September 10, 2019 At last. Brought tears to my eyes reading this. X Prescribed Venlafaxine 150mg .......... 19 Feb 2019 stopped Venlafaxine 150mg cold turkey. 06 March 2019 restarted Ven 125mg. 04 April 2019 9 mini pills. 02 May 2019 8 mini pills. 01July 2019 7 mini pills. 18 Aug 2019 6 mini pills. 24 Sept 2019 5.50 mini pills. 11 October 2019 5 mini pills. 5th May 2020 Reinstated Ven 125 mg XR 9 pills. 9th Nov 2020 Update Started splitting dose to twice per day 02/02/2021 can’t stabilise without symptoms. 03/02/21 9 mini pills @ 10am Updated.... July 2021 108mg, Sept 2021 107mg, tapering steps to be updated current dose 14 July 2023 80mg 23.07.23 75mg half way !
Caspur Posted September 10, 2019 Author Posted September 10, 2019 More news coverage: https://www.independent.co.uk/news/health/drugs-nhs-prescribe-patients-addictive-opioids-anti-depressants-painkillers-a9098491.html 2011 - started Venlafaxine (again) at 75mg Raised to 150 mg at some point - unsure of dates. Reduced back down to 75 mg. Doctor advised this would be a lifetime, maintenance dose 2017 - Side effects now intolerable. Started taper from June 15th - 5% dose reduction steps (two 12 hourly doses). 2017 - October 20th - took last dose of Venlafaxine - 4 mg. Debilitating symptoms followed. 2017/18 - diazepam - 8mg/day for 1 month - 7 week taper Feb 2018 2017/18 - duloxetine - max 90mg - now stopped 2018 - Feb 25mg quetiapine, increased to 50mg. 2018 - March/April - increased venlafaxine slowly (10mg steps) to 75 mg/day. Recovery from withdrawal followed. 2018 - July 13 - stopped quetiapine after 2 month taper. Late July - had to reinstate quetiapine due to intolerable withdrawal. Now tapering from 25mg 2019 - June - stopped quetiapine after 10 month taper. Mild insomnia only symptom. 2021 - June - venlafaxine approx 6.0 mg see Taper history details
bubbles Posted September 10, 2019 Posted September 10, 2019 Just popping this here. I posted a bit before this thread started, otherwise I'd have added them here: 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid
bubbles Posted September 10, 2019 Posted September 10, 2019 This is from the "What this report means for patients https://www.gov.uk/government/publications/prescribed-medicines-review-report/prescribed-medicines-review-what-this-report-means-for-patients "Some prescription medicines can be addictive and could cause problems for people taking them or coming off them, especially if someone has been taking them for a long time. These medicines include benzodiazepines and z-drugs, gabapentin and pregabalin, and opioid pain medicines. Antidepressants are not addictive but some people have problems coming off them." (emphasis mine) 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid
Caspur Posted September 10, 2019 Author Posted September 10, 2019 4 minutes ago, bubbles said: This is from the "What this report means for patients https://www.gov.uk/government/publications/prescribed-medicines-review-report/prescribed-medicines-review-what-this-report-means-for-patients "Some prescription medicines can be addictive and could cause problems for people taking them or coming off them, especially if someone has been taking them for a long time. These medicines include benzodiazepines and z-drugs, gabapentin and pregabalin, and opioid pain medicines. Antidepressants are not addictive but some people have problems coming off them." Hi Bubbles, Yes, this is a disappointing statement in the context of the report. The 'addictive' word is a difficult one regarding antidepressants and comes down to semantics in the end. However they are dependence forming. I have to take one to function normally because if I don't the withdrawal quickly becomes debilitating. I am dependent on this medication. Cheers Ed 2011 - started Venlafaxine (again) at 75mg Raised to 150 mg at some point - unsure of dates. Reduced back down to 75 mg. Doctor advised this would be a lifetime, maintenance dose 2017 - Side effects now intolerable. Started taper from June 15th - 5% dose reduction steps (two 12 hourly doses). 2017 - October 20th - took last dose of Venlafaxine - 4 mg. Debilitating symptoms followed. 2017/18 - diazepam - 8mg/day for 1 month - 7 week taper Feb 2018 2017/18 - duloxetine - max 90mg - now stopped 2018 - Feb 25mg quetiapine, increased to 50mg. 2018 - March/April - increased venlafaxine slowly (10mg steps) to 75 mg/day. Recovery from withdrawal followed. 2018 - July 13 - stopped quetiapine after 2 month taper. Late July - had to reinstate quetiapine due to intolerable withdrawal. Now tapering from 25mg 2019 - June - stopped quetiapine after 10 month taper. Mild insomnia only symptom. 2021 - June - venlafaxine approx 6.0 mg see Taper history details
bubbles Posted September 10, 2019 Posted September 10, 2019 1 minute ago, Caspur said: Hi Bubbles, Yes, this is a disappointing statement in the context of the report. The 'addictive' word is a difficult one regarding antidepressants and comes down to semantics in the end. However they are dependence forming. I have to take one to function normally because if I don't the withdrawal quickly becomes debilitating. I am dependent on this medication. Cheers Ed I agree it's mostly semantics. Can I stop? No? Addiction or dependence or somewhere in the crack in between - it doesn't make any practical difference. I couldn't stop, even when it was obvious that they were doing me damage and that's concerning. With SSRIs, taking it strictly as directed by my doctor, I became dependent (or addicted, or whatever). I can see no way to use them without becoming dependent given the long run in period needed. 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid
India Posted October 1, 2019 Posted October 1, 2019 On 9/10/2019 at 10:00 AM, bubbles said: Antidepressants are not addictive So disappointing to read this . 1999: Paroxetine (20mg). Age 16. 2007-2008: Fluoxetine (Prozac) for 1.5 years (age 25) Citalopram 20mg 2002-2005, 2009: Escitalopram (20mg), 2 weeks, (age 26) (adverse reaction)/*Valium 5mg/Temazepam 10mg 2010: Mirtazipine (Remeron)( do not remember dosage) 2010, 5 months. 2010-2017: Citalopram (20mg) (age 27 to 34) 2016: i.1st Sept- 31st Oct Citalopram 10mg , ii.1st November 2017-30th November 2017, Citalopram 5mg iii.1st December 2017- 4th February 2018, Citalopram 0mg, iv.5th February 2018- March 2018 Citalopram 5mg (10mg every other day) 28th February- tried titration of 5mg ( some adverse effects) 2018: 1st March 2018- 1st June Citalopram 10 mg (tablet form) /started titration 8mg , then 7 mg.2018: June 15th- 10th July Citalopram 10 mg pill every other day 2018: 10th July - 13th Sept Citalopram- 0mg (CBD oil first month of 0mg, passiflora on and off) 2018 13th Sept Citalopram 2mg , approx 16th Sept 4mg , approx 25th Sept 6mg held. 2019: 11 Feb 19: 7mg (instant bad rxn) 12 Feb 19 6mg held 1 May 19 5.4mg held 5 Oct 19 5.36mg 22 Oct 19 5.29mg 30 Oct 19 5.23mg 4/NOV/19 5.18mg 12 Nov 19 5.08mg 20 Nov 19 4.77mg 7 May 22 2.31mg 17/09/2023 0.8mg (Herbal/Supplements since 1st September: Omega Fish Oil 1200mg, 663mg of EPA- 2 tablets a day, magnesium and magnesium bath salts) I did not die, and yet I lost life’s breath - Dante
Caspur Posted October 3, 2019 Author Posted October 3, 2019 On 10/1/2019 at 10:34 PM, India said: So disappointing to read this . This was published in the Los Angeles Times and gives a reasonable view in my opinion. My opinion is that ADs are not addictive but they do cause dependence. https://www.latimes.com/opinion/story/2019-09-11/antidepressants-cause-dependence-not-addiction The Wikipedia entries are also quite useful: https://en.wikipedia.org/wiki/Substance_dependence https://en.wikipedia.org/wiki/Drug_addiciton 2011 - started Venlafaxine (again) at 75mg Raised to 150 mg at some point - unsure of dates. Reduced back down to 75 mg. Doctor advised this would be a lifetime, maintenance dose 2017 - Side effects now intolerable. Started taper from June 15th - 5% dose reduction steps (two 12 hourly doses). 2017 - October 20th - took last dose of Venlafaxine - 4 mg. Debilitating symptoms followed. 2017/18 - diazepam - 8mg/day for 1 month - 7 week taper Feb 2018 2017/18 - duloxetine - max 90mg - now stopped 2018 - Feb 25mg quetiapine, increased to 50mg. 2018 - March/April - increased venlafaxine slowly (10mg steps) to 75 mg/day. Recovery from withdrawal followed. 2018 - July 13 - stopped quetiapine after 2 month taper. Late July - had to reinstate quetiapine due to intolerable withdrawal. Now tapering from 25mg 2019 - June - stopped quetiapine after 10 month taper. Mild insomnia only symptom. 2021 - June - venlafaxine approx 6.0 mg see Taper history details
India Posted October 7, 2019 Posted October 7, 2019 On 9/10/2019 at 10:45 AM, bubbles said: agree it's mostly semantics. Can I stop? No? Addiction or dependence or somewhere in the crack in between - it doesn't make any practical difference. I concur . @CaspurThe problem, for me, is the subtext inferred out of the expression used. “Some” infers a minimal few. The tone downplays/minimises. No need to set up support groups for a minimal few. I’m with Baylissa on this: https://vimeo.com/84210031/comments 1999: Paroxetine (20mg). Age 16. 2007-2008: Fluoxetine (Prozac) for 1.5 years (age 25) Citalopram 20mg 2002-2005, 2009: Escitalopram (20mg), 2 weeks, (age 26) (adverse reaction)/*Valium 5mg/Temazepam 10mg 2010: Mirtazipine (Remeron)( do not remember dosage) 2010, 5 months. 2010-2017: Citalopram (20mg) (age 27 to 34) 2016: i.1st Sept- 31st Oct Citalopram 10mg , ii.1st November 2017-30th November 2017, Citalopram 5mg iii.1st December 2017- 4th February 2018, Citalopram 0mg, iv.5th February 2018- March 2018 Citalopram 5mg (10mg every other day) 28th February- tried titration of 5mg ( some adverse effects) 2018: 1st March 2018- 1st June Citalopram 10 mg (tablet form) /started titration 8mg , then 7 mg.2018: June 15th- 10th July Citalopram 10 mg pill every other day 2018: 10th July - 13th Sept Citalopram- 0mg (CBD oil first month of 0mg, passiflora on and off) 2018 13th Sept Citalopram 2mg , approx 16th Sept 4mg , approx 25th Sept 6mg held. 2019: 11 Feb 19: 7mg (instant bad rxn) 12 Feb 19 6mg held 1 May 19 5.4mg held 5 Oct 19 5.36mg 22 Oct 19 5.29mg 30 Oct 19 5.23mg 4/NOV/19 5.18mg 12 Nov 19 5.08mg 20 Nov 19 4.77mg 7 May 22 2.31mg 17/09/2023 0.8mg (Herbal/Supplements since 1st September: Omega Fish Oil 1200mg, 663mg of EPA- 2 tablets a day, magnesium and magnesium bath salts) I did not die, and yet I lost life’s breath - Dante
bubbles Posted October 8, 2019 Posted October 8, 2019 9 hours ago, India said: I’m with Baylissa on this: https://vimeo.com/84210031/comments Very interesting. 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid
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