Rocco Posted February 12, 2020 Posted February 12, 2020 I’m new to this forum. I have been on various antidepressants for 7 years. The first time on citalipram, after a difficult start, my anxiety improved. Subsequently I have tried various antidepressants, usually made me worse but scared to come off. My last episode I was prescribed Venlafaxine, but I developed buzzing in my muscles. It’s hard to describe this sensation, and tinnitus. This generally made me feel anxious. I have been off the Venlafaxine for five weeks now but the buzzing/shakiness is hard to manage. I wondered if anyone was able to advise me on this issue?
Moderator Emeritus Gridley Posted February 12, 2020 Moderator Emeritus Posted February 12, 2020 Welcome to SA, Rocco. Once you answered a few questions we'll be in a better position to help you. 1. What dose of Venlafaxine were you on? 2. How long were you on it? 3. Are the symptoms you're now experiencing (buzzing, shakiness) the same as when you were on the drug, a symptom you described as "buzzing in my muscles." 4. Did the buzzing in your muscles hit you very soon after you started taking the drug or did it develop gradually? 5. Did you have any other negative symptoms while on the drug and did they hit very soon or gradually? 6. Do you have any other symptoms now other than buzzing/shakiness? If so, please describe. 7. How is your sleep now as compared to when you were on the drug? 8. Did you have anxiety while you were on the drug, or did it develop after you quit? This is your Introduction topic, where you can answer my questions, ask your own and connect with other members. We're glad you found your way here. Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of Oct 15: 3.2mg Taper is 96% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg, iron, serrapeptase, nattokinase, L-Glutamine, milk thistle, choline I am not a medical professional and this is not medical advice. It is information based on my own experience as well as that of other members who have survived these drugs.
Rocco Posted February 13, 2020 Author Posted February 13, 2020 Thank you for replying. I will answer the points you raised: 1. I was on 112.5mgs. I started on 37.5mgs then increased the dose each month. after three months I was on 112.5mgs. 2. I was on 112.5mgs for nine months. 3. I’m now nearly into my six week since stopping. Over the last few weeks I think the muscular sensations are less obvious. If I pay attention to it or worry about it it intensifies. 4. I first noticed some strong twitching sensations about two months into starting Venlafaxine. These changed over time with less intensity but more frequent I mainly felt them across my back. This sensation reduced to buzzing/shaking sensations. As I write this I can see my GP looking sceptically at me! 5. My anxiety increased and sort of stayed at this raised level. I have done a course in Acceptance Commitment Therapy and Mindful based Stress Reduction. It’s with these tools I have sort of managed my anxiety. 6. increased anxiety as described above 7. I practice mindfulness to help with sleeping. I have had insomnia in the past but not recently. 8. I had anxiety increase on the drug. I think the muscular thing has become mire challenging as I came off it. Whilst I was stepping down it was manageable but two weeks in after stopping it has become challenging. I think I’m seeking reassurance that over time my nervous system will rebalance. Hopefully I’m nearly through the worst!! Thank you for any help you can give.
Moderator Emeritus Gridley Posted February 13, 2020 Moderator Emeritus Posted February 13, 2020 40 minutes ago, Rocco said: I will answer the points you raised: Rocco, Thanks for answering my questions. Two more: 1. Did you taper coming off the drug. If so, how fast? 2.Or did you stop it cold turkey? 3.What dose were you on when you stopped the drug? It sounds as if you are experiencing withdrawal from coming off the drug too fast. We recommend a slow taper of no more than 10% of current dose every four weeks. Why taper by 10% of my dosage? What is withdrawal syndrome. Daily Checklist of Antidepressant Withdrawal Symptoms (PDF) When we take medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur. It's also possible that you had an adverse (bad) reaction to the drug. Video: Healing From Antidepressants - Patterns of Recovery 40 minutes ago, Rocco said: I think I’m seeking reassurance that over time my nervous system will rebalance. Hopefully I’m nearly through the worst!! Yes, over time this will happen, whether your reaction was due to withdrawal or an adverse reaction. Unfortunately, no one can predict how long recovery will take. I too hope you're nearly through the worst. Normally, when a member is suffering withdrawal from a psychiatric drug, we mention the possibility of reinstatement of a very small dose of the drug. Reinstatement is the only known way to alleviate or reduce withdrawal symptoms. About reinstating and stabilizing to reduce withdrawal symptoms. -- at least the first page of the topic However, from your answers to my questions it appears you didn't have a good reaction to the drug (twitching, buzzing, shaking, anxiety). Is my conclusion correct? If so, reinstatement would not likely be a good option for you. It's very encouraging that your twitching has lessened. We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium (glycinate is a good form) and omega 3 (fish oil). Many people find these to be calming to the nervous system. Magnesium, nature's calcium channel blocker Omega-3 fatty acids (fish oil) Add in one at a time and at a low dose in case you do experience problems. Here are some links to help you deal with anxiety. Audio: First Aid for Panic (4 minutes) Audio: How to Recover from Anxiety - Dr Claire Weekes VIDEO: Peace from Nervous Suffering - Claire Weekes (1 hour) (http://sendvid.com/vgquc1dg) Anxiety Stuff - all kinds of stuff about anxiety attacks and things that help … 10 minute Restorative Yoga for Relaxation | Up the wall Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of Oct 15: 3.2mg Taper is 96% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg, iron, serrapeptase, nattokinase, L-Glutamine, milk thistle, choline I am not a medical professional and this is not medical advice. It is information based on my own experience as well as that of other members who have survived these drugs.
Rocco Posted February 14, 2020 Author Posted February 14, 2020 Thank you for that guidance. I suspect I have tapered too quickly, I took about 8 to 10 weeks. I think because the drug was more problematic for me I couldn’t see benefits to delaying. I will look into the advice given.
Moderator Emeritus ChessieCat Posted September 29, 2020 Moderator Emeritus Posted September 29, 2020 @Kromi Please start an Introduction topic for yourself here: Introductions and updates * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management
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