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Framer, 2021, What I have learnt from helping thousands of people taper off antidepressants and other psychotropic medications


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What I have learnt from helping thousands of people taper off antidepressants and other psychotropic medications

****** FramerSurvivingAntidepressants.org, San Francisco, California, USA

First Published March 16, 2021 Review Article


Although psychiatric drug withdrawal syndromes have been recognized since the 1950s – recent studies confirm antidepressant withdrawal syndrome incidence upwards of 40% – medical information about how to safely go off the drugs has been lacking. To fill this gap, over the last 25 years, patients have developed a robust Internet-based subculture of peer support for tapering off psychiatric drugs and recovering from withdrawal syndrome. This account from the founder of such an online community covers lessons learned from thousands of patients regarding common experiences with medical providers, identification of adverse drug reactions, risk factors for withdrawal, tapering techniques, withdrawal symptoms, protracted withdrawal syndrome, and strategies to cope with symptoms, in the context of the existing scientific literature.


Full text: https://journals.sagepub.com/doi/full/10.1177/2045125321991274

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Thank you. The paper, which I wrote, may be read, downloaded, or shared from the above link.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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Thanks so much for your article, which I’ve just read. Immediately thereafter, I sent it to my primary care doctor. Just three days ago I saw her and lectured her gently about AD withdrawal, though she was not the one who prescribed me. 

Fluoxetine 1997-2014, 2015, 10-40 mg. GAD and DR symptoms returned  April 2013.

Bupropion 2013-14, 4 mos; Lexapro 2014; Cymbalta 2014. Gabapentin 2014; Mirtazapene 2014. Buspirone 2015.

Venlafaxine Dec. 2015 – May 2019, 150 mg, tapered to 0 in 3 weeks, May-June 2019

Bupropion Mar 2017 – July 2019 300 mg, tapered to 0 in 3 weeks, July 2019

Fluoxetine/Prozac May 2019 – present, tapered from 20 mg started Jan 2020, linear 10% every 4 wks.; tapered 6 to 4 mg June, 2, 2020; 4 to 1.8 mg Aug. 26, 2020; updose from 1.8 mg to 2.0 Nov. 16, 2020. Holding at 2.0 mg as of Mar 14,2021. April 14, 2021 updosed to 2.5 mg.

D3 2,000 mg; Omega 3 360 EPA/240 DHA; Magnesium Chelate 250 mg; Inositol powder started Nov 12, 2020; Theanine 400 mg; cranial electrotherapy stimulation device, self-treatments started Mar 14, 2021.


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For those of us that live in the UK this paper has probably arrived at the perfect time.


ChessieCat linked to a Mad In America interview with Sherry Julo, Ed White and John Read:



In the interview, at approximately 31:58, Prof. Read mentions that the NHS is in the process of setting up support services, and that they will be looking to survey the various internet forums and Facebook groups to obtain information on the processes that have been proven to help. Altostrata has just handed them that information on a plate; they need to take advantage of it, and acknowledge that it represents the current best practice.

1999 - 2001: Paroxetine 20mg, 2003: Venlafaxine 75mg, 2003 - 2014: Escitalopram 20mg

1999 - December 2017: Lansoprazole 15mg

2014 - December 2017: Citalopram 20mg

December 2017: Mirtazapine 30mg, stopped after 4 days due to immediate bad reaction, Zopiclone 3.75mg, stopped after 2 days due to immediate bad reaction

January 2018 - April 2018: Citalopram liquid, tapering, final dose 0.1mg

December 2018 onwards: Vitamin C 1000mg

October 2021: Loratadine 10mg for 6 days (23/10 to 28/10)

Long term (for asthma): Salbutamol and Salmeterol inhalers, Salmeterol stopped March 2021 due to migraine headaches

Occasional use for headaches: Paracetamol 40mg or Ibuprofen 40mg

4th December 2021: Eustachian tube infection: Amoxicillin 500mg 3 per day for 5 days, Dexamethasone & Neomycin ear spray 3 per day for 1 week, Beclometasone nasal spray 2 per day for 2 weeks.

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