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PSSD Webinar on 29 July 2021. Healy and Reisman (Video)


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This Webinar is comprehensive on the topic of Post-SSRI Sexual Dysfunction (PSSD), hosted by the International Society for Sexual Medicine (ISSM), with the participation of Professor David Healy, psychiatrist, psychopharmacologist now working in Cananda, and Professor Yacov (Cobi) Reisman, urologist and sexologist in the Netherlands.


If you have the opportunity to share this video with patients, potential patients, specialists and doctors, it would be very helpful.


Perhaps the only important detail not considered here, due to the fact that it is so recent, is the first experimental study on this subject that was published, an Italian study which examined neurosteroid levels in rats during and after the administration of an SSRI, paroxetine, and found persistent changes following its discontinuation. This is very interesting, but it remains to be seen whether these changes are the same as those that can cause persistent sexual (sometimes also sensory, emotional and cognitive) dysfunction in some people who have previously taken serotonergic drugs.
Effects of paroxetine treatment and its withdrawal on neurosteroidogenesis (2021) https://authors.elsevier.com/c/1dTfu15hUdTGgL
Link to the full text valid until 14 September 2021.


I think you are already familiar with David Healy's intensive work on the PSSD.

Also Reisman has already written about PSSD in the literature:

I really appreciated his intervention in the Webinar, and his request to doctors to be honest with their patients, informing them of the side effects and risks of persistent dysfunction after discontinuation.  A couple of images: 



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