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marco123: 12 years paroxetine


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Hello all together,

paroxetine for 12 years. Wanted to stop 6 years ago, according to neurologist I should reduce 10mg every week, then only take 10mg every 2nd day.
What happened, massive depression. Then I took paroxetine again. tapering of now since almost 3 years.


Wish everyone that you succeed and get rid of it. 




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  • ChessieCat changed the title to marco123: 12 years paroxetine

Hello everyone,

I have a pericarditis since two weeks. I was not allowed to do any sports anymore (I usually go for a run 3 - 4 times a week). In addition, I have apparently, from the high-dose ibuprofen, sleep problems.
I have not stopped in the last 8 weeks, I am still on 1mg.
However, I now have strong symptoms, inner restlessness, especially in the legs, wake up at night at 3 o'clock and the thoughts race. Of course I had made another mistake and took a melatonin spray, because of the sleep disturbances.
My feeling is that something in the neurotransmitter balance is no longer right. The running was probably a good therapeutic agent.
Now I don't know what to do and I'm afraid. Sport is still not recommended or at least 2 months. The doctor (doesn't know anything about discontinuing, swears by medication) only gave me Opipramol so that I can at least sleep, but I suspect that even if I don't take it regularly, it won't be good, will it?
I am afraid that I will slip back into depression. Have considered again to go up a bit. But also no longer know what could make sense.

About an advice I would be happy!


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Welcome @marco123

I'm sorry you are struggling. How have you been tapering paroxetine this time? What dose are you at?

Tips for tapering off paroxetine (Paxil, Seroxat)

How do you talk to a doctor about tapering and withdrawal?


It is always a good idea to check for drug interactions: https://www.drugs.com/drug_interactions.html


And follow these guidelines:

Keep it simple, slow and stable


As there are common misconceptions about how these drugs work I found this post helpful to understand what is going on:

How Psychiatric Drugs Remodel Your Brain 


Coming off these drugs can cause many different withdrawal symptoms, often leading to doctors thinking the original condition is returning or that another mental illness has emerged.

What is withdrawal syndrome?

Dr. Joseph Glenmullen's withdrawal symptom checklist


When we recover, there are times of feeling OK mixed in with times of feeling bad.  This is called windows and waves.

The Windows and Waves Pattern of Stabilization  


Aside from a high quality fish oil and magnesium, be careful with supplements. Your central nervous system (CNS) has become sensitized from psychiatric drug use and can react unpredictably. Alcohol, caffeine, nicotine and other mind altering substances can make the condition worse.

Important topics about tests, supplements, treatments, diet


Here is our symptoms and self care section, you may find some useful ideas to help manage symptoms as you recover. 

Symptoms and self care topics 


To help us better advise you, can you please create a signature with all of the drugs that you are taking and have been taking in the last couple of years following these instructions:

How to List Drug History in Signature


I've given you quite a bit of information here.  Please read through it, and think about it, and we will take it from there. This is your Introductory topic, where you can ask questions and connect with other members.  We're glad you found your way here. Please stay in touch and let us know how you are doing.

Edited by Kiasofia

These are my opinions based on my own experience and what I have learned, not medical advice.


Drug history

2002-2019 Citalopram/Escitalopram, Lamictal
2019 April Escitalopram, quit at 10mg (withdrawal), Oct Escitalopram 10mg reinstated, quit after a few days (adverse reaction)

2019 Oct Lamictal cut from 200mg to 100mg
2019 Dec Lithium 83x2 mg

2020 Aug-Nov Lamictal tapered to 50 mg

2020 Nov 24 Lithium taper started, 30 Jan off Lithium

2021 15. March-31. May Lamictal tapered to 32.5 mg (holding)

2022 10. Jan started taking 25mg+5mg+2mg+0.5 liquid, 22. Jan went back to taking 25mg+5mg+half 5mg

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