PortugueseSea Posted October 15, 2022 Posted October 15, 2022 It seems that my inflammatory markers are a bit on the high end and that would potentially warrant an anti inflammatory supplement. I have been suggested Vitamin B6, Vitamin E, CoQ10 and sulforaphane by a friend knowledgeable about akathisia and withdrawal. Anybody has any experience with these and how did you take them? Thanks! December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN. March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg). April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol. May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound. May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. June 2023 - Added fish oil.Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2 Intro thread: https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/
EttaLouWho Posted October 20, 2022 Posted October 20, 2022 @PortugueseSeamine are high too. I was thinking about curcumin. Let me know what you decide to do. 1995 Prozac 1996 Prozac and Paxil 1997 Celexa 1998-2018 Cymbalta 60-120mg-- failed taper and restarted at 20mg after development of intense rage--finally able to taper off in late 2018 2017-2021 Clonazepam 0.5mg BID--discontinued over 4 weeks in April 2021 resulting in severe benzo withdrawal for 5 months maybe still ongoing at time of AD rapid taper in Dec 2021 2018-2019 Bupropion *Have been polydrugged since 1995 with a variety of benzos, sleeping pills, anxioltyics, and ADs. Too many to list or remember. Never properly tapered by doctor before switching medicines* 2020 Started on Buspirone 15mg three times a day 2020-2021 Antidepressant was changed three times: Trintellix, Pristiq, Fluvoxamine. Underwent 6 months of ketamine infusions. Advised to discontinue all meds due to inefficacy in November 2021. Weaned off Fluvoxamine by psychiatrist over 6 weeks-- last dose ~December 10, 2021. Severe ongoing withdrawal. February 2021 Started on 300mg Gabapentin for anxiety, restless legs, insomnia, and wide spread body pain from withdrawal. Began Gabapentin taper to 200mg on 8/5/2022. Worsened withdrawal symptoms. Also began 2000mg of L-Tryptophan for depression/AD withdrawal, 2400mg of N Acetyl Cysteine for OCD and 300mg of Magnesium for depression. Began L-Tryptophan taper from 2000mg to 1500mg on 8/14/2022. Completed l-tryptophan and NAC taper on 8/29/2022. Current Meds: 15mg of Buspirone twice a day (morning and night since 2020), 5 mg Buspirone at midday (Started taper of midday dose from 15mg to 5 mg in September 2023) , 200mg of gabapentin at night (Since August 2022), 1mg of alprazolam at night (Started at 0.25mg in Jan 2023 and gradually upped to 1-2mg three times a week until end of 11/2023--reinstated 1mg daily on 12/1/2023), 80mg propranolol in the morning, 10mg Zyrtec in the morning, birth control pills Current Supplements: 300 mg of magnesium citrate midday, 1000mg of Fish Oil in the morning, 1mg melatonin at night
PortugueseSea Posted October 25, 2022 Author Posted October 25, 2022 I am thinking Vitamin E but given that I just recently changed my magnesium, I am dosing twice a day now, will probably wait a bit before starting! 1 December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN. March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg). April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol. May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound. May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. June 2023 - Added fish oil.Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2 Intro thread: https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/
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