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Patients Taking Psychiatric Meds Often Gain Weight. Scientists May Now Know Why


Tridentata

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The research was done using a couple of antipsychotic drugs, and I don't know whether this would be generalizable to other antidepressants. But for what it's worth:

 

https://www.drugs.com/news/patients-psychiatric-meds-often-gain-weight-scientists-may-now-know-why-116994.html

Amitriptyline: prescribed 10 mg/day in mid-August 2022

  • Began fairly quick taper 18 October 2022 to 3 mg by 9 November (no withdrawal symptoms)
  • Reinstated at 10 mg on 9 November leading to some serious sleep disturbance
    • 10–17 November, tried 8 or 9 mg
    • 18 November, 10 mg
    • 19–22 November, 3.5 mg after advice to drop back to taper level
    • 23 November – 14 Dec., 3 mg
    • 15–22 Dec., 2.7 mg
    • 23 Dec. 2022 to 3/15/2023, ranged from 2.5 mg up to 3 mg w/partial reinstatement after bad crash provoked by CBD/THC gummy, then slowly back down to 2.5 with long hold in March
    • from 15 March 2023, continued slow taper (Brassmonkey slide, 2.5% week + 2 week hold every 4 weeks) to 1.2 mg as of 1/1/24. Increased tapering speed to 20% in 6 weeks, probably bad idea.

Other medications: albuterol inhaler as needed, acetaminophen as needed

Supplements: daily multivitamin, magnesium glycinate 400 mg/day PRN, probiotics
Caffeine: Max 1 cup coffee/day or 2 cups of tea

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