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Vitamin deficiency


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Can antidepressant withdrawal actually be the cause of vitamin deficieny or is that not likely? 

If your blood tests show you low in a vitamin is it more likely there is another cause or is it known here that withdrawal causes blood test ranges to be out of whack? 

 

2015- Jan 2021 20mg Citalapram

Jan 2021- April 2021 Sertraline (CT)

June 2021 - Fluoxetine & Trazadone

Oct 2021- Trazadone to Quitiapin 

Oct 2021 to June 2022 switches Duloxetine then paroxatine then Venlafaxine.

June 2022- venlafaxine for 5 or 6 weeks at 37.5 twice daily. Upped for one week to 75mg twice daily but caused panic attacks. Dropped back down to 37.5 twice daily. Panic attacks stopped. 

1 week- 62.5mg 1 week- 50mg 1 week- 37.5mg 1 week - 25mg 

ANTIDEPRESSANT FREE SINCE JULY 22ND 2022!! 

18/05/23 - 01-06/23 doxycycline for a rat bite 

Taken propranalol since 2015. 80mg.

21/11/22 76mg. 28/11/22 72mg. 05/12/22 68mg. 19/12/22 64mg. 27/12/22 60mg. 02/01/23 56mg. 09/01/23 50mg. 16/01/23 47mg. 23/01/23 44mg. 29/01/23 40mg. 05/02/23 38mg. 12/02/23 35mg. 19/02/23 32mg. 25/02/23 27mg. 04/03/23 25mg. 11/03/23 22mg. 17/03/23 19mg. 24/03/23 20mg. 05/04/23 18mg. 11/04/23 16mg. 17/04/23 14mg. 27/04/23 20mg. 19/06/23 19mg. 25/06/23 20mg. 04/08/23 18mg. 11/08/23 17mg. 16/08/23 16mg. 25/08/23 15mg. 01/09/23 14mg. 08/09/23 13mg. 15/08/23 12mg. 22/09/23 11mg. 29/09/23 10mg. 19/11/23 9mg. 26/11/23 8mg. 03/12/23 7mg. 10/12/23 6mg. 17/12/23 5mg. 24/12/23 4mg. 31/01/23 3mg. 07/01/24 2mg. 13/01/24 1mg. 19/01/24 0mg. DONE! 

 

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  • Moderator

Not seen anywhere that vitamin deficiency can result from withdrawal. Likely you are not getting the right vitamins from your  diet. 

"Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig 

 

I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. 

 

In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. 

 

Aug  2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg,  xanax prn, wellbutrin for a few months, trazodone prn 

Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used)

Aug 2018 - citalopram 40 mg (self titrated up)

September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0

Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd

March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week

Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering)

citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg,  7/27/19 -1.5 mg,  8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg

 

Supplements: magnesium citrate and bi-glycinate

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I wasn't sure if the drugs themselves can cause it 

2015- Jan 2021 20mg Citalapram

Jan 2021- April 2021 Sertraline (CT)

June 2021 - Fluoxetine & Trazadone

Oct 2021- Trazadone to Quitiapin 

Oct 2021 to June 2022 switches Duloxetine then paroxatine then Venlafaxine.

June 2022- venlafaxine for 5 or 6 weeks at 37.5 twice daily. Upped for one week to 75mg twice daily but caused panic attacks. Dropped back down to 37.5 twice daily. Panic attacks stopped. 

1 week- 62.5mg 1 week- 50mg 1 week- 37.5mg 1 week - 25mg 

ANTIDEPRESSANT FREE SINCE JULY 22ND 2022!! 

18/05/23 - 01-06/23 doxycycline for a rat bite 

Taken propranalol since 2015. 80mg.

21/11/22 76mg. 28/11/22 72mg. 05/12/22 68mg. 19/12/22 64mg. 27/12/22 60mg. 02/01/23 56mg. 09/01/23 50mg. 16/01/23 47mg. 23/01/23 44mg. 29/01/23 40mg. 05/02/23 38mg. 12/02/23 35mg. 19/02/23 32mg. 25/02/23 27mg. 04/03/23 25mg. 11/03/23 22mg. 17/03/23 19mg. 24/03/23 20mg. 05/04/23 18mg. 11/04/23 16mg. 17/04/23 14mg. 27/04/23 20mg. 19/06/23 19mg. 25/06/23 20mg. 04/08/23 18mg. 11/08/23 17mg. 16/08/23 16mg. 25/08/23 15mg. 01/09/23 14mg. 08/09/23 13mg. 15/08/23 12mg. 22/09/23 11mg. 29/09/23 10mg. 19/11/23 9mg. 26/11/23 8mg. 03/12/23 7mg. 10/12/23 6mg. 17/12/23 5mg. 24/12/23 4mg. 31/01/23 3mg. 07/01/24 2mg. 13/01/24 1mg. 19/01/24 0mg. DONE! 

 

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  • Moderator

Withdrawal I haven't heard to cause it. Drug treatment I am not sure - it has to depend on the drug and whether they compete for absorption with the specific vitamin. When you open your drug box, there is a leaflet there. Do you see the leaflet mention that about your drug? 

OMW

"Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig 

 

I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. 

 

In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. 

 

Aug  2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg,  xanax prn, wellbutrin for a few months, trazodone prn 

Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used)

Aug 2018 - citalopram 40 mg (self titrated up)

September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0

Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd

March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week

Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering)

citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg,  7/27/19 -1.5 mg,  8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg

 

Supplements: magnesium citrate and bi-glycinate

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I'm not on any any more but I took a lot of different rubbish 

2015- Jan 2021 20mg Citalapram

Jan 2021- April 2021 Sertraline (CT)

June 2021 - Fluoxetine & Trazadone

Oct 2021- Trazadone to Quitiapin 

Oct 2021 to June 2022 switches Duloxetine then paroxatine then Venlafaxine.

June 2022- venlafaxine for 5 or 6 weeks at 37.5 twice daily. Upped for one week to 75mg twice daily but caused panic attacks. Dropped back down to 37.5 twice daily. Panic attacks stopped. 

1 week- 62.5mg 1 week- 50mg 1 week- 37.5mg 1 week - 25mg 

ANTIDEPRESSANT FREE SINCE JULY 22ND 2022!! 

18/05/23 - 01-06/23 doxycycline for a rat bite 

Taken propranalol since 2015. 80mg.

21/11/22 76mg. 28/11/22 72mg. 05/12/22 68mg. 19/12/22 64mg. 27/12/22 60mg. 02/01/23 56mg. 09/01/23 50mg. 16/01/23 47mg. 23/01/23 44mg. 29/01/23 40mg. 05/02/23 38mg. 12/02/23 35mg. 19/02/23 32mg. 25/02/23 27mg. 04/03/23 25mg. 11/03/23 22mg. 17/03/23 19mg. 24/03/23 20mg. 05/04/23 18mg. 11/04/23 16mg. 17/04/23 14mg. 27/04/23 20mg. 19/06/23 19mg. 25/06/23 20mg. 04/08/23 18mg. 11/08/23 17mg. 16/08/23 16mg. 25/08/23 15mg. 01/09/23 14mg. 08/09/23 13mg. 15/08/23 12mg. 22/09/23 11mg. 29/09/23 10mg. 19/11/23 9mg. 26/11/23 8mg. 03/12/23 7mg. 10/12/23 6mg. 17/12/23 5mg. 24/12/23 4mg. 31/01/23 3mg. 07/01/24 2mg. 13/01/24 1mg. 19/01/24 0mg. DONE! 

 

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  • Mentor

"Two principal mechanisms may explain higher tHcy and lower folate and B12 levels in response to treatment with antipsychotics—either decreased food vitamin intake or increased demands. Given that patients’ diet was similar in the course of the study as they were treated in the same hospital and changes in tHcy were similar in all tertiles of baseline folate and vitamin B12 levels, it is most likely that increased demands underlie presented findings."

 

Looks like APs do and I wouldn't be surprised if ADs affect things too. I gotta get to work, but worth looking into what you took and what has been found to affect things. If you find any good studies and/or resources, can you share with us? 

Pronouns: they/them/theirs 

Started on Prozac in early 2000s to treat cPTSD, been on various cocktails ever since.

2002-2004, 2017-2022: Buspar, tapered down to 0

2016-present: 100mg Seroquel for sleep -> May 2023: 90mg -> June 2023: 81mg -> September 2023: 72mg -> switched to brand name, much too strong, down to 60mg -> October 2023: 54mg -> November 2023: 50mg -> January 2024: 45mg -> April 2024: 40.5mg

2016-Present: 100mg Wellbutrin SR -> January 2023: 75mg IR (37.5mg 2x a day) -> February 2023 (33.75mg 2x a day) -> July 2023 (30.37mg 2x a day) -> August 2023: 27.33mg 2x a day 

2018-present: 25mg Pristiq

2015-present: 600mg Gabapentin (200mg 3x a day) -> December 2022: 300mg Gabapentin (100mg 3x a day) per GP's recommendation after side effects -> March 2023: 90mg 3x a day (switched to liquid suspension) -> April 2023: 81mg 3x a day -> September 2023: bad generic, switched back to homemade liquid; too strong after bad generic, down to 70mg 3x a day, still bad. Adjusted slowly till at 60mg 3x a day, much better. Long hold till -> December 2023: 54mg, still feels too high after November Seroquel switch from brand name to generic, doc recommended 50mg which feels better -> January 2024: When Wellbutrin went down, Gabapentin started putting me to sleep, went down to 45mg, then 41mg to stay awake, so far so good -> February 2024: 36mg, still too high, 34mg -> March 2024: 31mg, STILL too high, 30mg

Supplements: Multivitamin w/magnesium, probiotics, digestive enzymes, anti-viral nitric oxide nose spray as needed

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According to the study linked below, there is some evidence that SSRIs may affect folate, calcium and vitamin D levels.

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874849/

 

Other than that article, there isn't very much information about it, apart from a lot of websites repeating the same information, or using scare tactics about vitamins, in general, to try and sell their supplements. Or opinion pieces without any data to back them up.

 

Once off the medication, a healthy diet and getting out in the sunshine should sort any deficiencies out pretty quickly. The majority of people don't need vitamin supplements.

 

On a side note, I've read an increasing number of articles lately from scientists saying they think they've got the whole vitamin D thing wrong. And we may all naturally have wildly varying amounts of the stuff, meaning the blood tests are pointless. So I wouldn't be at all surprised if all the advice about it is reversed over the next few years.

Oct 2018 - Jun 2020: 10 mg per day generic Escitalopram in pill form.

Jul 2020 - Aug 2020: Switched to 9 mg per day of Cipralex drops to aid tapering.

Sep 2020 - Oct 2020: Taper to 8 mg.

Nov 2020 - Dec 2020: Taper to 7 mg.

Jan 2021 - Feb 2021: Taper to 6 mg.

Mar 2021 - Apr 2021: Taper to 5 mg.

May 2021 - Jun 2021: Taper to 4 mg.

Jul 2021 - Sep 2021: Taper to 3 mg.

Sep 2021 - Jan 2022: Taper to 2 mg.

Jan 2022: Stopped taking altogether.

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