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zack: Olanzapine taper


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Hello everyone! I'm glad to be part of this community. I would like to share some information about my medication
history and ask a few questions. English is not my first language, so please excuse any mistakes. In June 2020, my
psychiatrist prescribed Zoloft (50mg), Abilify (10mg), and Zyprexa (5mg) for depression and anxiety. Unfortunately, I tapered
off Zoloft too quickly and developed PSSD. Now, I take Zyprexa and Abilify. I started tapering off Zyprexa using
the liquid method on my own in March 2024, but I don't think the drug distributes evenly in the water. I can't find
Ora-plus where I live. Can you recommend an alternative? Should I use a regular tablet or an orodispersible tablet
when preparing the liquid? Finally, is it possible to taper two antipsychotics at the same time? Thank you!

2015 - 2017 olanzapine

2018 - 2020 escitalopram, aripiprazole , metoprolol

2020 - 2022 sertraline

2020 - 2024 olanzapine, aripiprazole

2024  olanzapine 16 Mar 4.5mg 13 Apr 4.1mg

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  • KenA changed the title to zack: Olanzapine taper
  • Moderator

Hi zack,

 

Welcome to SA. Thank you for summarizing your drug history in your signature.

 

On 4/25/2024 at 9:11 AM, zack said:

I started tapering off Zyprexa using
the liquid method on my own in March 2024, but I don't think the drug distributes evenly in the water.

 

Why do you think it doesn't distribute evenly in water? Many members, myself included, have been tapering from Zyprexa using the water titration method.

 

On 4/25/2024 at 9:11 AM, zack said:

Should I use a regular tablet or an orodispersible tablet
when preparing the liquid?

 

A regular tablet should be fine to use when preparing a liquid but how are you preparing it today?

 

On 4/25/2024 at 9:11 AM, zack said:

Finally, is it possible to taper two antipsychotics at the same time?

 

We recommend only tapering one medication at a time so if symptoms arise, it is easy to identify the cause.

 

Thanks,

 

Firefly

 

Pre- October 2022: Wellbutrin, Escitalopram, CitalopramSertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda

Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg -> May 12, 2024 = 0.63mg

Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022.

Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg

 

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Hi, thank you for your reply, FireflyFyte. I am currently using regular tablets. After stirring the mixture, I see that the particles quickly sink to the bottom. I wasn't sure if I was taking the correct dose.

2015 - 2017 olanzapine

2018 - 2020 escitalopram, aripiprazole , metoprolol

2020 - 2022 sertraline

2020 - 2024 olanzapine, aripiprazole

2024  olanzapine 16 Mar 4.5mg 13 Apr 4.1mg

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  • Moderator
2 hours ago, zack said:

After stirring the mixture, I see that the particles quickly sink to the bottom.

 

This is just filler and can be ignored. As long as you are stirring the mixture well, the dose should be even.

 

Pre- October 2022: Wellbutrin, Escitalopram, CitalopramSertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda

Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg -> May 12, 2024 = 0.63mg

Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022.

Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg

 

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Thank you for your help.

 

2015 - 2017 olanzapine

2018 - 2020 escitalopram, aripiprazole , metoprolol

2020 - 2022 sertraline

2020 - 2024 olanzapine, aripiprazole

2024  olanzapine 16 Mar 4.5mg 13 Apr 4.1mg

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