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StephenC: Seroquel withdrawal suggestions/advice please


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Hello all,


My name is Stephen and I am posting from Australia.


I have just been through a rocky 2 years of SSRI CT withdrawal.  I completely shocked my nervous system and could not tolerate small milligrams of antidepressants as a result.


During this time I have been on 25mgs of Seroquel IR in the evening.  Prescribed off-label for anxiety.  I would now like to withdraw properly off this medication.  


I have attempted to reduce the Seroquel previously by a quarter of a tablet (25%).  But have experienced severe nausea and some anxiety.  I figured this was an indication the dose reduction was too much for my nervous system and reverted back to the full dose before all hell broke lose again. 


Does anyone have any suggestions/experience on withdrawal off Seroquel?  The tablets are very small and fiddly.


Thanks for taking the time to read my post.




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Hi Stephen,

Welcome to SA and thank you for posting an introduction.  Congratulations on getting getting through 2 years of withdrawals from SSRI CT,  I know what that's like, I've been in protracted withdrawal for about that long.


Nausea is a common withdrawal symptom from stopping Seroquel too fast, so that was a good indication that you need to taper slower.  We generally recommend reducing by 10% a month, here is a link to a thread with some tips about how to reduce Seroquel by small amounts:




You will find a lot of friendly help and support here, please let us know how things go.



I'm not a doctor.  My comments are not medical advise. These are my opinions based on my own experience and what I've learned. Please discuss your situation with a medical practitioner who has knowledge of tapering and withdrawal...if you are lucky enough to find one.

My Introduction Thread

Full Drug and Withdrawal History

Brief Summary

Several SSRIs for 13 years starting 1997 (for mild to moderate partly situational anxiety) Xanax PRN ~ Various other drugs over the years for side effects

2 month 'taper' off Lexapro 2010

Short acute withdrawal, followed by 2 -3 months of improvement then delayed protracted withdrawal

DX ADHD followed by several years of stimulants and other drugs trying to manage increasing symptoms

Failed reinstatement of Lexapro and trial of Prozac (became suicidal)

May 2013 Found SA, learned about withdrawal, stopped taking drugs...healing begins.

Protracted withdrawal, with a very sensitized nervous system, slowly recovering as time passes

Supplements which have helped: Vitamin C, Magnesium, Taurine

Bad reactions: Many supplements but mostly fish oil and Vitamin D

June 2016 - Started daily juicing, mostly vegetables and lots of greens.

Aug 2016 - Oct 2016 Best window ever, felt almost completely recovered

Oct 2016 -Symptoms returned - bad days and less bad days.

April 2018 - No windows, but significant improvement, it feels like permanent full recovery is close.

VIDEO: Where did the chemical imbalance theory come from?

VIDEO: How are psychiatric diagnoses made?

VIDEO: Why do psychiatric drugs have withdrawal syndromes?

VIDEO: Can psychiatric drugs cause long-lasting negative effects?

VIDEO: Dr. Claire Weekes




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