MysteryBrains Posted January 29, 2015 Posted January 29, 2015 Hello, everyone. I have been taking venlafaxine xr 225 mg for almost ten years now. The crises that induced my depression are long over, and I am eager to wean myself of this drug. I hate the zaps and clicks, vertigo, trembling etc. but the sudden nuclear rage is what really frightens me. This site is an absolute goldmine of useful information and experience and I think before I begin to taper I will glean as much as I can of your collective wisdom. Thanks for going to the trouble and effort to share. Currently take venlafaxine XR 225 Mg daily for past 9 years occasional hydroxyzine 25mg sleep. Took Paxil in past, stopped without symptoms.
Moderator Emeritus Fresh Posted January 29, 2015 Moderator Emeritus Posted January 29, 2015 Welcome Mysterybrains , you have indeed found a goldmine here. There's a whole section on tapering . . . and you're in good company with your experiences here. Best wishes , Fresh 1987-1997 pertofran , prothiaden , Prozac 1997-2002 Zoloft 2002-2004 effexor 2004-2010 Lexapro 40mg 2010-2012Cymbalta 120mg Sept. 2012 -decreased 90mg in 6months. Care taken over by Dr Lucire in March 2013 , decreased last 30mg at 2mg per week over 3 months. July 21 , 2013- last dose of Cymbalta Protracted withdrawal syndrome kicked in badly Jan.2014 Unrelenting akathisia until May 2014. Voluntary hosp. admission. Cocktail of Seroquel, Ativan and mirtazapine and I was well enough to go home after 14 days. Stopped all hosp. meds in next few months. July 2014 felt v.depressed - couldn't stop crying. Started pristiq 50mg. Felt improvement within days and continued to improve, so stayed on 50mg for 8 months. Began taper 28 Feb. 2015. Pristiq 50mg down to 45mg. Had one month of w/d symptoms. Started CES therapy in March. No w/d symptoms down to 30mg. October 2015 , taking 25mg Pristiq. Capsules compounded with slow-release additive. March 2016 , 21mg
Moderator Emeritus Petunia Posted January 29, 2015 Moderator Emeritus Posted January 29, 2015 Welcome MysteryBrains, thank you for posting an introduction and for filling out your signature. Are the zaps, clicks, vertigo, rage etc side effects you get from taking venlafaxine, or it this what you experience when you try to stop taking it? How did you stop taking Paxil in the past? Did you switch straight over to Venlafaxine? We suggest reducing by no more than 10% of the current dose every 4 weeks, this reduces the risk of withdrawal symptoms arising. Please read through this which will explain why: Why taper by 10% of my dosage? (The general philosophy of gradual tapering) Here is out topic with tips specifically for tapering venlafaxine: http://survivingantidepressants.org/index.php?/topic/272-tips-for-tapering-off-effexor-and-effexor-xr-venlafaxine/ You can use this thread as your ongoing journal to track progress and communicate with the community, add to it whenever you want. I'm glad you found us. Petunia. I'm not a doctor. My comments are not medical advise. These are my opinions based on my own experience and what I've learned. Please discuss your situation with a medical practitioner who has knowledge of tapering and withdrawal...if you are lucky enough to find one. My Introduction Thread Full Drug and Withdrawal History Brief Summary Several SSRIs for 13 years starting 1997 (for mild to moderate partly situational anxiety) Xanax PRN ~ Various other drugs over the years for side effects 2 month 'taper' off Lexapro 2010 Short acute withdrawal, followed by 2 -3 months of improvement then delayed protracted withdrawal DX ADHD followed by several years of stimulants and other drugs trying to manage increasing symptoms Failed reinstatement of Lexapro and trial of Prozac (became suicidal) May 2013 Found SA, learned about withdrawal, stopped taking drugs...healing begins. Protracted withdrawal, with a very sensitized nervous system, slowly recovering as time passes Supplements which have helped: Vitamin C, Magnesium, Taurine Bad reactions: Many supplements but mostly fish oil and Vitamin D June 2016 - Started daily juicing, mostly vegetables and lots of greens. Aug 2016 - Oct 2016 Best window ever, felt almost completely recovered Oct 2016 -Symptoms returned - bad days and less bad days. April 2018 - No windows, but significant improvement, it feels like permanent full recovery is close. VIDEO: Where did the chemical imbalance theory come from? VIDEO: How are psychiatric diagnoses made? VIDEO: Why do psychiatric drugs have withdrawal syndromes? VIDEO: Can psychiatric drugs cause long-lasting negative effects? VIDEO: Dr. Claire Weekes
Moderator Emeritus Rhiannon Posted January 29, 2015 Moderator Emeritus Posted January 29, 2015 Welcome MB! Started on Prozac and Xanax in 1992 for PTSD after an assault. One drug led to more, the usual story. Got sicker and sicker, but believed I needed the drugs for my "underlying disease". Long story...lost everything. Life savings, home, physical and mental health, relationships, friendships, ability to work, everything. Amitryptiline, Prozac, bupropion, buspirone, flurazepam, diazepam, alprazolam, Paxil, citalopram, lamotrigine, gabapentin...probably more I've forgotten. Started multidrug taper in Feb 2010. Doing a very slow microtaper, down to low doses now and feeling SO much better, getting my old personality and my brain back! Able to work full time, have a full social life, and cope with stress better than ever. Not perfect, but much better. After 23 lost years. Big Pharma has a lot to answer for. And "medicine for profit" is just not a great idea. Feb 15 2010: 300 mg Neurontin 200 Lamictal 10 Celexa 0.65 Xanax and 5 mg Ambien Feb 10 2014: 62 Lamictal 1.1 Celexa 0.135 Xanax 1.8 Valium Feb 10 2015: 50 Lamictal 0.875 Celexa 0.11 Xanax 1.5 Valium Feb 15 2016: 47.5 Lamictal 0.75 Celexa 0.0875 Xanax 1.42 Valium 2/12/20 12 0.045 0.007 1 May 2021 7 0.01 0.0037 1 Feb 2022 6 0!!! 0.00167 0.98 2.5 mg Ambien Oct 2022 4.5 mg Lamictal (off Celexa, off Xanax) 0.95 Valium Ambien, 1/4 to 1/2 of a 5 mg tablet I'm not a doctor. Any advice I give is just my civilian opinion.
OffEFFexor Posted January 29, 2015 Posted January 29, 2015 Hey MB, your history has some similarity to mine (ten years Effexor 225mg, prozac prior to that.) Check my story if you like; http://survivingantidepressants.org/index.php?/topic/7538-offeffexor-hello-everybody/ I quit cold turkey, it really sucked, and I would not recommend that method. 1983-1995: On and off several tricyclic ADs1995: Quit alcohol, started Prozac2003: Stopped Prozac; 2004: Started Effexor XR 2252014: Tried and failed three rapid tapers; stopped cold turkey March 11, 2014, eight days of Prozac as a bridge.March 19, 2014: SSRI/SSNI free; four weeks acute withdrawal, then five month window of minimal symptoms.Sept 2014-June 2015: Delayed, prolonged severe withdrawal from Effexor. Roller coaster, way up and way down. Symptoms swing widely. Clear improvement in Mar-Apr, but still much hell. In May symptoms shifted to insomnia and depression, less HA, tinnitus and brain fog. July-Sept 2015: After two weeks of using CES device, tremendous relief of insomnia, depression and other symptoms. Feeling much better, finally! Symptoms still come and go, good and bad days.Sneaking up on return to good health. Alto gave me a 'Here Comes the Sun'!!! ☼ Oct 2015-Feb 2016: Difficult several months, some good days but the bad days felt like I'm moving backwards. Struggling after steady improvement, but hanging tough. Current supplements: Mg-Threonate; glutathione; krill oil; borage oil; phosphatidyl choline; multivite, vit B12, vit C, vit D vit E; OTC meds pseudoephedrine in the AM and benadryl at bedtime. Clonidine 0.2 bid for high blood pressure. Filled with hope, courage and self-appreciation.
MysteryBrains Posted February 2, 2015 Author Posted February 2, 2015 Hi Petunia; I had very little difficulty coming off the paxil. I just kept forgetting to take it, because I disliked its side effects, and eventually, just stopped. It was about ten years later when I started taking the effexor xr. The experience of missing a dose is how I know about the brain zaps, trembling, clicks, rage, tearfulness etc. Once, I ran out and had to go to the emergency room. The unpleasantness is serious and starts almost immediately, within I would say, 6 hours, not a couple days. There is no confusion about what is going on. I know paxil has a short half-life, and can be very difficult for some. I never had any of the sensations I have with venlafaxine xr. Currently take venlafaxine XR 225 Mg daily for past 9 years occasional hydroxyzine 25mg sleep. Took Paxil in past, stopped without symptoms.
Moderator Emeritus Petunia Posted February 2, 2015 Moderator Emeritus Posted February 2, 2015 If you use the 10% method of tapering recommended here and take your dose regularly, you should be able to taper off with minimal discomfort. Its great that you are here and learning all you can before starting your taper, I'm sure you will do well. This link probably contains most of what you might need to know about tapering: Important topics in the Tapering forum and FAQ I'm not a doctor. My comments are not medical advise. These are my opinions based on my own experience and what I've learned. Please discuss your situation with a medical practitioner who has knowledge of tapering and withdrawal...if you are lucky enough to find one. My Introduction Thread Full Drug and Withdrawal History Brief Summary Several SSRIs for 13 years starting 1997 (for mild to moderate partly situational anxiety) Xanax PRN ~ Various other drugs over the years for side effects 2 month 'taper' off Lexapro 2010 Short acute withdrawal, followed by 2 -3 months of improvement then delayed protracted withdrawal DX ADHD followed by several years of stimulants and other drugs trying to manage increasing symptoms Failed reinstatement of Lexapro and trial of Prozac (became suicidal) May 2013 Found SA, learned about withdrawal, stopped taking drugs...healing begins. Protracted withdrawal, with a very sensitized nervous system, slowly recovering as time passes Supplements which have helped: Vitamin C, Magnesium, Taurine Bad reactions: Many supplements but mostly fish oil and Vitamin D June 2016 - Started daily juicing, mostly vegetables and lots of greens. Aug 2016 - Oct 2016 Best window ever, felt almost completely recovered Oct 2016 -Symptoms returned - bad days and less bad days. April 2018 - No windows, but significant improvement, it feels like permanent full recovery is close. VIDEO: Where did the chemical imbalance theory come from? VIDEO: How are psychiatric diagnoses made? VIDEO: Why do psychiatric drugs have withdrawal syndromes? VIDEO: Can psychiatric drugs cause long-lasting negative effects? VIDEO: Dr. Claire Weekes
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