I'm just interested in whether anyone has done research in to why most of us can be rapidly titrated up to a large dose of an AD or AP without the brain having the complete melt down that it does if these drugs are rapidly removed? Surely the initial introduction of them throws just a bigger wrench in the gears of our brains' delicate neurochemistry, yet if this caused the dilemma that rapid removal does, none of use would have ever tolerated any psychoactive drug for more than a week.