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Questions and answers about liquid medications, use by date, expiry

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ryan1982

Perfect- thanks, Chessie. I’ll stay on the pills for now unless anyone thinks liquid could work better. 

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ChessieCat
13 hours ago, jozeff said:

🤗🤗

Well, a syringe has what is called a dead volume. This is the volume that doesn't come out the syringe when you empty it! This only applies for the first check mark, in this case the first ml. If you empty a 5 ml syringe let's say from 5 ml mark to 4 ml you gave exactly 1 ml liquid. Same for 4 to 3 ml same for 3 to 2 ml. Same for 2 to 1 ml. Same for 1 to 0 ml, but in the latter case you will have some dead volume left in the syringe. You should left this in the syringe because it is designed this way!

 

So, if you suck up liquid in a syringe let's say from nothing to 1 ml mark. Thet total volume of liquid in your syringe is maybe 1.2 ml. This is 1 ml + 0.2 ml dead volume. If you empty the syringe it will release 1 ml. The 0.2 ml dead volume stays in the syringe.

 

If you taper using syringes use the 5 ml syringe from 5 to 1 ml if possible. Below 1ml use the 1 ml syringe. 

Never fill a syringe with another one because the dead volume messes up your calculation.

 

If you need let's say 4.6 ml you take the 5ml syringe and fill it to 4 ml. 

Empty this in a small cup, leave the dead volume in the syringe (the liquid that stays in the tip).

Fill your 1 ml syringe to 0.6 ml mark and empty it in the same cup., Leave the dead volume in the syringe.

Drink your liquid and flush you cup with water and drink that too. 

Flush your syringe with water and throw that away. Dry the tip of syringe with some toilet paper.

Don't drink de dead volume because you will be getting more than 4.6 ml...

 

Hope this is clear. It's important to do the same every day. That way you get the most accurate dosage.

 

I use a volumetric pipette for this (an old one from the lab) but this is not necessary. A syringe will do, I mean we are not talking about 1/1000 of a mg right? One day 5.45 mg and next day 5.46 will be ok. Such a small difference is negligible.

 

 

Good luck!!!

 

Jozeff

Analytical chemist

 

 

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SkyBlue

If anyone can weigh in on liquid Paxil (expiry/use by date), that would be great. I'm using the manufacturer's oral suspension. 

 

Post moved, explanation added by CC

 

Edited by ChessieCat
added info

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ChessieCat
14 minutes ago, SkyBlue said:

If anyone can weigh in on liquid Paxil, that would be great. I'm using the manufacturer's oral suspension. 

 

The oral solutions of a drug are different from the tablet form and I think it would be best to use before the expiry date and start a new bottle before the recommended time after first opening.

 

You might need to see a knowledgeable pharmacist to get the information about Paxil oral.  If you do get it, please add it to the Tips for Tapering Paxil topic because I've done some fairly indepth searching and can't find anything.  Only about storage temperature.  Thank you.

 

I found this for Lexapro the other day.  From:  https://www.lundbeck.com/au/products/our-products/lexapro/lexapro-oral:

 

Quote

Storage 

Keep LEXAPRO oral solution in a cool dry place where the temperature stays below 25°C. 

Discard LEXAPRO oral solution 10 mg/mL 3 months after first opening. 

Discard LEXAPRO oral solution 20 mg/mL 2 months after first opening

 

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nick1990

From what I’ve seem through some

research Skyblue, liquid suspensions are different and for the most part should be used before expiry . 

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SkyBlue
2 hours ago, ChessieCat said:

 

You might need to see a knowledgeable pharmacist to get the information about Paxil oral.  If you do get it, please add it to the Tips for Tapering Paxil topic because I've done some fairly indepth searching and can't find anything.  Only about storage temperature.  Thank you.

 

 

Will do. 

 

Yes, @nick1990, that sounds right. Better be safe than sorry of course!

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Frogie

I just checked the expiration date on my liquid Lexapro. It’s manufactured by Camber. 

 

This was filled last month, and expires January, 2020. 

 

So, it’s good for 1 year as long as it’s kept in a cool dark place. Don’t refrigerate it or keep it in the medicine cabinet. That’s what my pharmacist told me.

 

 

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ChessieCat
2 hours ago, Frogie said:

So, it’s good for 1 year as long as it’s kept in a cool dark place.

 

That's unopened.  Once it is open it will only be viable for a certain number of months

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Frogie
3 hours ago, ChessieCat said:

 

That's unopened.  Once it is open it will only be viable for a certain number of months

Ok, my pharmacist is wrong then. She said as long as it was kept in a cool dry place it was good for expiry date on the label. I’ll have to let her know.

 

Thanks for the information. I really appreciate your knowledge 😊

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ChessieCat
6 hours ago, Frogie said:

I just checked the expiration date on my liquid Lexapro. It’s manufactured by Camber. 

 

This was filled last month, and expires January, 2020. 

 

So, it’s good for 1 year as long as it’s kept in a cool dark place. Don’t refrigerate it or keep it in the medicine cabinet. That’s what my pharmacist told me.

 

 

 

Expiry date (unopened) is different from the after opening time/discard time.

 

I found this information recently:

 

From:  https://www.lundbeck.com/au/products/our-products/lexapro/lexapro-oral:

 

Quote

Storage 

Keep LEXAPRO oral solution in a cool dry place where the temperature stays below 25°C. 

Discard LEXAPRO oral solution 10 mg/mL 3 months after first opening. 

Discard LEXAPRO oral solution 20 mg/mL 2 months after first opening

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Frogie
2 hours ago, ChessieCat said:

 

Expiry date (unopened) is different from the after opening time/discard time.

 

I found this information recently:

 

From:  https://www.lundbeck.com/au/products/our-products/lexapro/lexapro-oral:

 

Thank you for the valuable information.

 

I’m going to talk to my pharmacist about this matter. Obviously she is mistaken.

 

Once again I appreciate your knowledge on this matter. It makes a huge difference in the amount of time to keep the medication.

 

Hope you are doing well.

 

Take care,

Frogie xx

 

 

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