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shady1, going off Pristiq


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Alto - thanks for contributing !

You are a lifesaver.




I have been on 100 mg of Pristiq for a few years and am simply trying to get to 50 mg.

I have read & re-read multiple citations (on this site) and remain confused.


Can you -or- Can't you cut the Pristiq tablets, in order to taper?

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Welcome, shady1. I made your post your Introduction -- you deserve a topic of your own.


Yes, you can cut up Pristiq tablets, or crush them into a powder to weigh. See Tips for tapering off Pristiq (desvenlafaxine)


I hope this helps answer some of your questions.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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Hi Shady. Welcome to the forum. I haven't had experience with Pristiq. Mine was Paxil. I'm glad you found your way here. Very helpful people are here :)

Taper from Cymbalta, Paxil, Prozac & Antipsychotics finished June 2012.

Xanax 5% Taper - (8/12 - .5 mg) - (9/12 - .45) - (10/12 - .43) - (11/12 - .41) - (12/12 - .38)

My Paxil Website

My Intro

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Hi Shady,


I am cutting Pristiq into quarters and have taken 37.5 mg for like a week without any issues.


Also my pdoc told me its totally fine to cut the tablets.


Please see the tips section,suggested by alto.

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Hi Shady


Nice to meet you. Not a Pristiq person...but have been thru WD a few times with SSRI's.


This site will really be of help for you:)

Intro: http://survivingantidepressants.org/index.php?/topic/1902-nikki-hi-my-rundown-with-ads/


Paxil 1997-2004

Crossed over to Lexapro Paxil not available

at Pharmacies GSK halted deliveries

Lexapro 40mgs

Lexapro taper (2years)


Imipramine and Celexa

Now Nefazadone/Imipramine 50mgs. each

45mgs. Serzone  50mgs. Imipramine

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