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Annra: Looking for advice


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Hi all,


I am looking for advice about reinstating after screwing up and not following what all of you have so carefully laid out here.


I tried the tapering method a few months ago and it made me really anxious so I stopped. A couple of weeks ago, I was feeling really good, forgot to take my meds for a few days, then just decided to keep going with that.


Needless to say, it didn't go well -- palpitations, sweats, brain zaps, nausea.


This past Saturday, I started back on 50 mg. of sertraline and I added half the buspirone on Sunday. I am feeling much better but still shaky. My main symptom is nausea and my spine feels kind of shaky. I slept well on Sunday night but last night was rough -- woke up about 2 hours after falling asleep. Was up a few times but mananged to get some good sleep in between.


My questions:

- Should I continue with the 50 mg. sertraline or go down to 25?

- Should I continue with the buspirone or forget about it for now? 


Anything gentle advice is welcome. 


2000: started with fluoxetine for anxiety/depression

2002-ish?: switched to sertraline

2010-ish?: added buspirone to help with sexual side effects

usual dose between 50-75 mg of sertraline (sometimes higher dose in the winter)

usual dose 15 mg buspirone (it's supposed to be b.i.d but I usually just take it in the morning

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  • ChessieCat changed the title to Annra: Looking for advice
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Hi, Annra. Welcome to Surviving Antidepressants. 


Here are some links about your drugs and about tapering: 


Tips for tapering off sertraline (Zoloft)


Tips for tapering off buspirone (Buspar)


Taking multiple psych drugs? Which drug to taper first?


Why taper by 10% of my dosage?


The Windows and Waves Pattern of Stabilization


On 10/26/2021 at 11:23 AM, Annra said:

My questions:

- Should I continue with the 50 mg. sertraline or go down to 25?

- Should I continue with the buspirone or forget about it for now? 


It depends on the length of time between when you stopped the drugs and when you re-started, as well as the dose you stopped at. If you've been off the drug for a few weeks or months, your nervous system may hyper-reactive to too high a dose, so you'll want to reinstate at a much lower dose than you stopped at. Please read the first post of this thread:


About reinstating and stabilizing to reduce withdrawal symptoms


Here is what we need:


  1. Please tell us more about how you came off these drugs, especially the rate you tapered and the date and dose you stopped. 
  2. Please tell us the time(s) of day you take your drugs. The reason I ask is there's a MAJOR drug interaction between buspirone and sertraline.

              Drug Interaction Checker Report


Please add a signature.  Include drugs, doses, dates, and discontinuations & reinstatements in the last 12-24 months. Also include supplements. This will help us give you the most accurate advice we can. 

  • Any drugs and supplements prior to 24 months ago can just be listed with start and stop years. 
  • Please use actual dates or approximate dates (mid-June, Late October) rather than relative time frames (last week, 3 months ago) 
  • Spell out months, e.g. "October" or "Oct."; 9/1/2016 can be interpreted as Jan. 9, 2016 or Sept. 1, 2016. 
  • Please leave out symptoms and diagnoses. 
  • A list is easier to understand than one or multiple paragraphs. 
  • This is a direct link to your signature:  Account Settings – Create or Edit a signature.

As you provide more information, we can better guide you in reinstating and provide other information, as well. 



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