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Robyn22: Ready to give Prozac the boot


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Hello, I am 63 and past ready to give my 25-year  use of Prozac the boot. I did stop way back for a couple of years, I don't recall any major WD. I've tried several times since but the irritability is overwhelming, for me and my husband. I started on 20mg and have taken as much as 80mg, presently taking 40mg.  I have had never tapered, wasn't aware I needed to. I did wean a 25-year addiction to Xanax a couple of years ago and am finally starting to learn how to sleep again. I would appreciate a plan I can work with. I also have hypothyroidism and adrenal issues which can exasperate my the symptoms of irritability.

Thanks for your time and help,

1091 first started Prozac, 20mg, I took it about a year and stopped. 1095 started Prozac 20mg  and increased to 80mg between 1097 and 2014. I stopped all and restarted with 20mg 2014-2015. 1096 started Xanax 1mg for insomnia and gradually increased to 2mg. Weaned 2017-2018 I used a nail file to taper my doses.
2017 I became very ill with untreated hypothyroidism, adrenal insufficiency, and reactivated EBV. That is when I became proactive regarding my health or lack thereof. Presently I take on a daily basis;

NDT, liothyronine, hydrocortisone, fludrocortisone, fluoxetine, magnesium, C, B-complex, B-12, NAC, cod liver oil, iodine, DIM, probiotic, neem, bioidentical estrogen, Holy Basil, Jujube, Renova, zinc, potassium

I sure hope this will suffice, thank you.

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  • Moderator Emeritus

Welcome to SA, Robyn22.  I'm so glad you found us before beginning your taper.  We have some very specific plans and suggestions for your taper of Prozac.  


Please add a signature.  Include drugs, doses, dates, and discontinuations & reinstatements in the last 12-24 months. Also include supplements. This will help us give you the most accurate advice we can.  Just add dates to the information in your post and include your xanax taper.  This information will appear below all your posts and is a big help to the moderators.
  • Any drugs and supplements prior to 24 months ago can just be listed with start and stop years. 
  • Please use actual dates or approximate dates (mid-June, Late October) rather than relative time frames (last week, 3 months ago) 
  • Spell out months, e.g. "October" or "Oct."; 9/1/2016 can be interpreted as Jan. 9, 2016 or Sept. 1, 2016. 
  • Please leave out symptoms and diagnoses. 
  • A list is easier to understand than one or multiple paragraphs. 
  • This is a direct link to your signature:  Account Settings – Create or Edit a signature.

We recommend tapering no faster than 10% of your current dose every four weeks.  Some have to go slower.


Why taper by 10% of my dosage?


The following link is specifically about tapering Prozac and includes information about how to get the smaller doses you'll need for a 10% taper.  You have a choice between tapering with liquid Prozac, making your own liquid, or cutting the pills and using the AWS Gemini-20 scale (available on Amazon) to weigh.

Tips for tapering off Prozac (fluoxetine)


The 10% method works for a broad number of people, but as I said some people have to go slower.  A micro-taper is the gentlest way to come off these drugs.



The Brassmonkey Slide is a way of making micro-taper reductions weekly, as opposed to a larger reduction once a month. I'm using this method to taper off 20mg Lexapro.
We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium (magnesium glycinate is a good form) and omega 3 (fish oil). Many people find these to be calming to the nervous system. 




Please research all supplements first and only add in one at a time and at a low dose in case you do experience problems.
This is your Introduction topic, where you can post updates, ask questions and connect with other members.  Please feel free to write back with any questions.






Gridley Introduction


Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.


Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg Valium 

End 2021  year 1 of Valium taper at 6mg

End 2022 year 2 of Valium taper at 2.75mg 

End 2023 year 3 of Valium taper at 1mg

Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper.

Taper is 95% complete.


Imipramine 75 mg daily since 1986.  Jan.-Sept. 2016 tapered to 14.4mg  

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5mg and shift to Valium taper

Jan. 24, 2024: Resume Imipramine taper.  Current dose as of June 28: 5mg

Taper is 93% complete.  


Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg, iron, serrapeptase, nattokinase, L-Glutamine

I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs.

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  • ChessieCat changed the title to Robyn22: Ready to give Prozac the boot

Hi @Robyn22 and welcome to the group! Congratulations on deciding to taper yourself off of these awful drugs. Although you have successfully quit Antidepressants in the past, every time you go through the withdrawal experience there is a chance the withdrawal symptoms will be worse, so I'm very glad that you found this form to help you do your taper properly. Hopefully with the guidance of the caring and informed moderators here you'll have minimal symptoms. I'm currently 9 months  Prozac free after 11 years and benzodiazepine free (Valium) after 7 years, and although I'm still taking medication for severe chronic pain, I haven't felt this good in years! I actually feel like myself, it's wonderful! It's also a really good idea to educate yourself as much as possible there are so many things that can interfere with your healing process.So please hang in there it's a difficult Journey but well worth it! Stay strong and feel free to contact me anytime sincerely laydefish


Edited by ChessieCat
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2 years Drug History Prior to Tapering:

Between 2011 & 2018 I had approximately 58 dose changes between the 4 main medications I took as well as 14 new medications add & taken away.

Prozac (Fluoxetine):(Aug 2016-Dec 2016: 60MG),(June 2017-Nov 2017: 60MG),(Dec 2017: 80MG),(June 2017-Sept 2 2018: 60MG),(Sept 3 2018-Sept 5 2018: 40MG),(Sept 6 2018-Sept 8 2018: 20MG),(Sept 9 2018: 0MG).

Cymbalta:(Jan 2017-May 2017: 60MG).

Cyclobenzaprine: (Aug 2016: 30MG,(Feb 2017: 30MG).

Diazepam (Valium):(Aug 2016-Sept 15 2016: 30MG),(Sept 16 2016-Oct 2017: 15MG),(Nov 2017-Aug 19 2018: 6MG),(Aug 20 2018: 0MG).

Gabapentin:(Aug 2016-Aug 3 2018: 2400MG),(Aug 4 2018-March 26 2019: 2000MG),(March 27 2019-March 30 2019: 1600MG),(May 1 2019: 2000MG)

Hydrocodone:(Aug 2016-Oct 2016: 10-325/4daily),(Nov 2016-Feb 2017: 10-325/3daily),(March 2017-April 2017: 5-325/4daily),(May 2017-April 2018: 10-325/3daily),(June 2018-Aug 25 2018: 10-325/5daily),(Aug 26 2018-Sept 2 2018: 4.5daily),(Sept 3 2018-Sept 10 2018: 10-325/4daily),(Sept 11 2018-Sept 18 2018: 10-325/3daily),(Sept 19 2018-May 1 2019: 10-325/3.5 daily).

Oxycodone: May 2018: 10-325MG/4daily). 

Please see my Intro for full drug history.

         **Forgive Yourself For Not Knowing What You Didn't Know Before You Knew It!  -Maya Angelou/

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