MisterS Posted June 2, 2020 Posted June 2, 2020 Hi all, Breifly, I stopped taking fluoxetine in February after 3 years on it, with 7 previous years on different SSRIS. I didn’t taper. its been 3/4 months now, and I want to ask if what I’m experiencing could be withdrawal, and if anyone has experienced any of the more unusual symptoms below**. 1. intense emotions and sadness. 2. EXTREME irritability 3. loss of pleasure in pretty much everything 4. (** I don’t know how to describe this, but a strong, impulsive feeing of hopelessness, feeling trapped in my existence), almost like a suicidal feeling, and subsequent terror that I’m actually suicidal. 5. Impulse to self harm (never acted on, possibly OCD resurfacing). Im struggling immensely. If alarm bells are ringing, rest assured Im not going to act on the impulses. They feel unnatural and dystonic. Could the above be withdrawal? Is it possible to experience withdrawal after 3 months, especially on fluoxetine with its long half life?
Moderator Emeritus Gridley Posted June 2, 2020 Moderator Emeritus Posted June 2, 2020 Welcome to SA, MisterS. All the symptoms you describe are very typical withdrawal symptoms resulting from your cold turkey of fluoxetine. Yes, it is very possible to experience withdrawal after 3 months; there is often a honeymoon period of 3 months with withdrawal symptoms hitting hard at that point. Fluoxetine, like all psychiatric drugs, requires tapering, and its long half life doesn't change that necessity; all the long half-life does is to delay withdrawal. It is not self-tapering. What is withdrawal syndrome. Daily Checklist of Antidepressant Withdrawal Symptoms (PDF) When we take psychiatric medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur. These drugs alter the architecture of the brain, and the time necessary to heal the brain and return to homeostasis is, unfortunately, impossible to predict. Withdrawal symptoms arise because your body got used to the drug being present and now has to work very hard to accommodate its absence. Brain Remodelling Reinstatement of a very small dose of the original drug is the only known way to help alleviate withdrawal syndrome. The only other alternative is to try and wait out the symptoms and manage as best you can until your central nervous system returns to homeostasis. Unfortunately no one can give you an exact timeline as to when you will start feeling better and while some do recover relatively easily, for others it can take many months or longer. Reinstatement isn't a guarantee of diminished symptoms for everyone but it's the best tactic available. You're just outside the time period where reinstatement predictably works, up to 3 months after last dose. So it might work or it might not. We usually suggest a much smaller reinstatement dose than your last dose. These drugs are strong, your system has become sensitized and If you take too much it may be too much for your brain and can cause you become more unstable. Then, once you've stabilized on the reinstated dosage, which can take several months, you can begin a 10% per month taper down to zero. Please read: About reinstating and stabilizing to reduce withdrawal symptoms. -- at least the first page of the topic Let us know if you're interested in reinstating and we can suggest a reinstatement dosage. Please don't reinstate without letting us suggest a dosage. A question: What dosage were you on when you quit? We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. Magnesium, nature's calcium channel blocker Omega-3 fatty acids (fish oil) Add in one at a time and at a low dose in case you do experience problems. This is your Introduction topic, where you can ask questions and connect with other members. We're glad you found your way here. Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of Oct 15: 3.2mg Taper is 96% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg, iron, serrapeptase, nattokinase, L-Glutamine, milk thistle, choline I am not a medical professional and this is not medical advice. It is information based on my own experience as well as that of other members who have survived these drugs.
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