LTurner Posted May 14, 2022 Share Posted May 14, 2022 In November 2021 I had a galvanic facial the lady didn’t ask if I had metal in my mouth, suffered suspected thermal injuries to alveolar nerves. Burning in mouth, pain in teeth. 7 months of barely any sleep to date neurologist suggests nortriptilyne try for 1 day terrible reaction to it March try amitriptyline for nerve pain up and down through fear as hate drugs makes burning mouth worse with dryness so stop Another doctor says try mirtazipine take for 2 days neurologis says try her with pregablin take for 4 days terrible reactions Doctor says ok to stop but there were 3 in my system I now realise plungef into dreadful state, doom intense sweating, not knowing where I am, huge changes in skin hair, bowels whole endocrine system like this for 1 week with zero sleep (was only 2 hours per night since November£ ) then doctor says try some zoplicone gives me 2 hours that’s it Another doctor says just anxiety take some beta blockers I take for 1 week up and down dose through fear stop them Doctor reinstates mirtazipine for sleep but barely sleeping currently have dreadful feeling of glovus Sensation permanently in throat, can’t tolerate heat, baths makes me feel incredibly poorly, depersonalisation amongst millions of other things extreme dryness suspecting auto immune, joints making awful sound, do not know who the bell I am mouth 100 times worse am presuming histamine intolerance below surface Want off mirtazipine as feeling heavily suicidal, do not think I will ever stabilise on it feeling like no hope for future my whole brain and body completely damaged Please help? 3 young kids very high achiever before facial Link to comment
LTurner Posted May 14, 2022 Author Share Posted May 14, 2022 Massage, touch anything makes the feeling in my throat so much worse. Body stuck in sympathetic mode and unable to get out of it. Hated all drugs before this. Can see no hope just want off mirtazipine but wheezing a lot on it. Do not think I will ever stabilise on mirtazipine, too late to reinstate any others Link to comment
LTurner Posted May 14, 2022 Author Share Posted May 14, 2022 Suspecting all neurotransmitters completely crashed. Family turned against me as every doctor says drugs out of system. Feeling so alone with no hope Link to comment
Administrator Altostrata Posted May 20, 2022 Administrator Share Posted May 20, 2022 Welcome. What drugs are you taking now, at what times o'clock and dosages? To help us out, follow these instructions Please put your drug and withdrawal history in your signature You may need to use a computer to do this. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
LTurner Posted May 24, 2022 Author Share Posted May 24, 2022 Hi Altostrata, thanks for your reply, I’m taking 15mg mirtazipine on an evening but it hasn’t alleviated anything. I suspect there may be mastosytosis at play under the surface which has been exacerbated hugely by the drugs j just want off mirtazipine but prior to thdd we drugs I had 5 months of barely any sleep due to trauma. Now I sleep maybe an hour-2 a night on mirtazipine, that’s it no idea where to go from here. I feel like mirtazipine simply kept me alive but my body and mind are in such a state now I don’t think I’d survive getting off it but it’s just making all other issues worse staying on it. if I only sleep like that on mirtazipine I dread to think of the state of my brain Link to comment
Administrator Altostrata Posted May 24, 2022 Administrator Share Posted May 24, 2022 Not sure what's going on. You could have a medical condition that coincidentally became apparent at the time you had a disastrous facial. We don't provide general medical care here. Strongly recommend you talk to a specialist about your throat symptoms, as well as suspected mastocytosis or histamine intolerance. This site is for tapering off psychiatric drugs and recovery from withdrawal syndrome. While you may have had adverse reactions to psychiatric drugs, it doesn't sound like you have withdrawal syndrome per se. Some people who have immediate adverse reactions to psychiatric drugs have symptoms very much like protracted withdrawal for months. We advise those people to be patient and cope with symptoms. You may or may not have some benefit from the mirtazapine you're taking. I'd ask questions about that but you have not supplied the drug and withdrawal history in your signature as requested. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Roserdl Posted May 25, 2022 Share Posted May 25, 2022 Mirtazapine for sleep works only at lower doses. Anything above 7.5 doesn't really work. I take 3.5 with melatonin and it greatly helped the sleep issue. Maybe talk to a mid on how to taper the mirtazapine down to a level to help your insomnia. Recent 2018 Zoloft 150mg (20 years taking at various times, no real issues before stopping) 2019 Risperdal one month low dose (forget amount) stopped bad reaction 2019 Remeron 7.5 mg sleep (discontinued in mid 2019) on for six months (tapered for a few weeks) Zoloft 100 mg Summer 2020/Zoloft 75 mg Summer 2021 Zoloft 50 mg November 2021/ Zoloft 25 mg First two weeks January 2022: Reinstated 50 mgJanuary Last week) Crash in February - on and off doses as doctors conflicted over serotonin syndrome/withdrawal - stopped all for two week & resumed:\ Other drugs tried in hospitals (Abilify, 1mg, 1 dose, Zyprexa 1 dose 1mg, Klonopin .25 4 doses in 2 hospitalizations) March 1 titrated Zoloft up from 0 to 65 from February to Early May Severe vision problems at 65 mg (improved depression) Taper to 55 6/15, 45mg 7/15/ 35mg 8/1, 25mg 8/15, 10 mg, 8/31 OFF 9/2022 Omg Improved with drops from August to September - November crash ONE dose Zoloft 3mg 11/17 - worsened symptoms - Remain off Zoloft Mirtazapine -3.5 mg six weeks mid march to end april, occasionally for sleep Supplements: Fish oil, magnesium, lions mane, cytokine suppress, MCT Oil Link to comment
Administrator Altostrata Posted May 25, 2022 Administrator Share Posted May 25, 2022 1 hour ago, Roserdl said: Mirtazapine for sleep works only at lower doses. Anything above 7.5 doesn't really work. I take 3.5 with melatonin and it greatly helped the sleep issue. Maybe talk to a mid on how to taper the mirtazapine down to a level to help your insomnia. Is that so? @Roserdl We have many people here who have taken doses far higher than 15mg mirtazapine for sleep. You might use site search in the Introductions forum to see for yourself. 1 This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Mirtazapine20mg Posted May 25, 2022 Share Posted May 25, 2022 In support of @Altostrata's view: It is plenty sedating at 18 mg which is my current dosis. Also worked like a charm at 30 mg. My personal experience (N=1) is that Mirtazapine does have an activating effect at higher doses, but it is rather short lived (in my case 3 months-ish, but that is more than enough time for mania to develop) and after that you are left with same sedating effect once again. So in my case (again N=1) I am highly adaptable to the activating effect of Mirtazapine (albeit with a time lag), but not the sedating effect of Mirtazapine. That by the way would explain why I at the same time feel sedated and agitated during withdrawal. In the scientific litterature you do often find the Mirtlow: sedating>activating, MirtHigh: sedating<activating description, and if you 20 years ago made a short term study of me, say 8 weeks, that would be the result you would get. 1 2004: (apr): Citalopram 20 mg, June 60 mg., dec 20 mg 2004 (dec): Mirtazapine 15 mg. 2014 (Jun): Citalopram stop cold turkey. Began 10 mg Vortioxetine 2017: (dec): Mirtazapine 15 mg ->30 mg (after three day stint on psych ward) 2020: (aug): Vortioxetine 10 mg stopped cold turkey. 2020 (dec): Mirtazapine 30 mg -> 15 mg (GPs instructions) 2021 (feb): Mirtazapine reinstatement 26,25 mg 2022 (Jan): Mirtazapine (5% taper): 14. Jan 24,9 mg, 6. feb 23,7 mg, 1. marts 22,5 mg, 15. marts 21,3 mg, 2. april 20 mg, 26. april 19. mg, 25. may 18.1 mg, 26 jun 17 mg. Have always taken fish oil capsules. Do not drink alcohol when tapering. 1 multivitamin pill a day. Try to eat healthy, but impossible on mirtazapine. Link to comment
Roserdl Posted May 26, 2022 Share Posted May 26, 2022 7.5 to 15 mg typical for sleep. Its more sedating at lower doses. Tons of literature on it. Some people find better sleep benefits do to this. And multiple prescribed have told me the same thing. I'm on phone or would provide links. I get effects at 3.5. Just offering up some information. I wasn't trying to get into a big debate. I hope you find some relief in any case. Recent 2018 Zoloft 150mg (20 years taking at various times, no real issues before stopping) 2019 Risperdal one month low dose (forget amount) stopped bad reaction 2019 Remeron 7.5 mg sleep (discontinued in mid 2019) on for six months (tapered for a few weeks) Zoloft 100 mg Summer 2020/Zoloft 75 mg Summer 2021 Zoloft 50 mg November 2021/ Zoloft 25 mg First two weeks January 2022: Reinstated 50 mgJanuary Last week) Crash in February - on and off doses as doctors conflicted over serotonin syndrome/withdrawal - stopped all for two week & resumed:\ Other drugs tried in hospitals (Abilify, 1mg, 1 dose, Zyprexa 1 dose 1mg, Klonopin .25 4 doses in 2 hospitalizations) March 1 titrated Zoloft up from 0 to 65 from February to Early May Severe vision problems at 65 mg (improved depression) Taper to 55 6/15, 45mg 7/15/ 35mg 8/1, 25mg 8/15, 10 mg, 8/31 OFF 9/2022 Omg Improved with drops from August to September - November crash ONE dose Zoloft 3mg 11/17 - worsened symptoms - Remain off Zoloft Mirtazapine -3.5 mg six weeks mid march to end april, occasionally for sleep Supplements: Fish oil, magnesium, lions mane, cytokine suppress, MCT Oil Link to comment
Administrator Altostrata Posted June 22, 2022 Administrator Share Posted June 22, 2022 @LTurner how are you doing? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
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