Moderator Emeritus manymoretodays Posted November 14, 2022 Moderator Emeritus Posted November 14, 2022 (edited) https://www.madinamerica.com/2022/11/anders-sorensen-tackling-psychiatric-drug-withdrawal-research-practice/ Another James Moore great interview done as part of "World Tapering Day" (4th, 5th, and 6th Nov). Held to raise global awareness of the need to safely taper psychotropic drugs. I listened and found it one of the more clearly articulated explanations of what happens when psych drugs occupy receptors, and then what happens when they are taken away. I thought it was great too, that Anders Sorensen also included the Antipsychotics (AP's) and the receptor occupations effect on dopamine, as well as the reverse......what happens when the drug is taken away to this neurotransmitter. We are often just hearing about the effect on serotonin, with the AD's(in particular SSRI's), and the receptor occupancy, and then changes when the drug is reduced in dose strength. So that was cool, that AP's were included in his answers to the interviewers questions. The interviewee, was also co-author of an article in Molecular Psychiatry, in 2021 titled: The relationship between dose and serotonin transporter occupancy of antidepressants- a systemic review I couldn't find that one, in our Journals and Scientific Evidence Topic, and could not gain access to it. Well worth a listen though, as the concept(s) we deal with here, ARE so clearly elucidated/articulated in this interview. If you are like me, and sometimes have to try multiple times to "get it" with some concepts, then this is for you. Have a nice listen. Or just read the transcript, which is often what I do. Edited November 14, 2022 by manymoretodays 2 Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks. Started with psycho meds/psychiatric care circa 1988. In retrospect, and on contemplation, situational overwhelm. Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time). 5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014) 12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs. My last psycho med ever! Tapered @ 10% every 4 weeks, sometimes 2 weeks to 2016 Dec 16, medication free!! Longer signature post here, with current supplements. Herb and alcohol free since 5/15/2016. And.....I quit smoking 11/2021. Lapsed. Redo of quit smoking 9/28/2022, and again finally 5/25/24. Can you say Hallelujah?(took me long enough)💜 None of my posts are intended as medical advice. Please discuss any decisions about your medical care with a knowledgeable medical provider. My success story: Blue skies ahead, clear sailing
Moderator Emeritus Gridley Posted November 19, 2022 Moderator Emeritus Posted November 19, 2022 On 11/14/2022 at 11:34 AM, manymoretodays said: I listened and found it one of the more clearly articulated explanations of what happens when psych drugs occupy receptors, and then what happens when they are taken away. I think this is a great interview for several reasons -- its clear explanation of withdrawal and receptor occupancy, its validation of what we've been saying here for so long about the importance of the hyperbolic (as opposed to linear) taper, and its laying out how much help can be provided by what we call non-drug coping skills. Absolutely excellent. Thanks for posting, mmt. 1 Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of Dec 28: 2.2mg Taper is 97% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg, iron, serrapeptase, nattokinase, L-Glutamine, milk thistle, choline I am not a medical professional and this is not medical advice. It is information based on my own experience as well as that of other members who have survived these drugs.
Recommended Posts