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BaldPhoenix - 1 pill of 50mg Sertraline


BaldPhoenix

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Hi all,

 

6 months ago, August 2022 I took a single 50mg pill of Sertraline. I decided to quit immediately since I felt very bad and developed sexual side effects within less than an hour.

The first 2 months, I felt lightheaded sometimes, had GI issues, and on and off sexual side effects. I figured these would improve with time - my life was bearable however.

 

At the 2 month mark, I started developing tingling in my hands and feet, and feeling like something in my brain "turned on" (left side)

These symptoms also came and left. My sexual side effects got worse. Total ED for like 2 months.

At this point, I started waking up with nausea at the mornings which usually went away after a couple hours, and developed brainfog.

 

This went on and off - until the 6 months mark (now)

I'm not sure what triggered this, I actually started feeling bad before this started so I'm not sure this is the cause, but I had to use antibiotics (Amoxicillin) because of a tooth extraction.

I remember feeling my sexual side effects subsiding during the week on the antibiotics. However, 2 weeks after stopping everything went to hell.

 

My hands and legs went numb, total ED again, brainfog. I rushed to the ER to try and understand what's going on - I was going back and forth between numbness and extreme muscle shakiness, anxiety and elevated heart rate.

No answers from the doctors yet. The next day my leg muscles couldn't stopped contracting up to the point where I developed hip pain and had problems sleeping at night.

My GI issues also got worse (started developing abdominal pain)

The neurological muscular issues went away luckily (I started taking B12 supplements as I thought the GI issues caused this due to malnutrition - also not sure)

My blood test are all fine.

 

This past week I'm in constant waves & windows, my penile sensitivity actually came back full force for 2 days after 6 months (I was shocked)

Then it left again (about 50%)

Then extreme nausea again. I am now suffering from brainfog & nausea again which comes and goes.

 

I'm now seeing a GI specialist to rule out other medical issues.

 

I really hope I recover from this.

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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  • Administrator

Welcome, @BaldPhoenix

 

We have a small population of people here who had severe adverse reactions to antidepressants almost immediately. See 

 

Adverse reactions to an antidepressant within a few doses -- how long for recovery?

 

These Intro topics are tagged with "immediate ADR". What we see is people have symptoms that look like protracted withdrawal syndrome and, like protracted withdrawal, they very, very gradually recover.

 

We have also seen antibiotics complicate adverse effects of psychiatric drugs or withdrawal syndromes. They clearly have some neurological effect.

 

How has your symptom pattern changed in the last 2 months?

 

To help us out, follow these instructions Please summarize your drug and withdrawal history in your signature You may need to use a computer to do this.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Thank you, @Altostrata
I edited my signature.

I'm not sure I'm an immediate ADR case. My initial symptoms were sexual dysfunction, GI issues and occasional light headedness in the beginning. (I felt bad the day I took that but that was it) Only after around 2 months the symptoms started getting worse.

 

Unfortunately my symptoms seem to be getting stronger, I'm not sure if it's because of the antibiotics or not.

In the last month I started developing muscle numbness which I didn't have before (this also comes and goes, previously I only had tingling)

Also my gut issues are as bad as they were in the beginning.

 

 

Is it common for symptoms to worsen 4-6 months after quitting Zoloft?

 

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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Gut issues seem to be resolved now.

However muscle numbness is getting stronger and I'm having a lot of pain in my legs...

 

And there's also a lot of anxiety, I'm always on edge. I never had this before, hope it passes soon.

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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  • Administrator

LIke withdrawal syndrome, post-discontinuation effects from an ADR may come and go and change into other symptoms as your nervous system repairs itself in patches.

 

Anything that might be causing the anxiety? Are you taking other drugs, supplements, alcohol?

 

Good to hear the gut issues have resolved.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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I'm not taking anything at the moment, no. (The physical anxiety is gone however)

I'm thinking of starting probiotics however (GI issues on and off again)

 

Currently with severe brain fog... It's crazy how much damage one pill can do and I'm not normal after 6 months.

 

I'll try to update here once in a week or two, the constant reading and researching makes me really paranoid that I'll stay like this for years.

Hope it gets better soon

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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Hey same thing happened to me 9 months ago from a single pill.. you’re not alone 

April 2022- Only 1 celxa pill 10mg

had an adverse reaction & never took anymore again 

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@peaceandlove What are your symptoms?
Do you have any gut issues?

 

I'm starting to look into gut because my symptoms are always worse when my gut issues are worse.

I also read a lot about PSSD cases on Reddit where they fixed their symptoms by fixing their gut (Dysbiosis / SIBO)

 

Gut issues might just be a symptoms of withdrawal, but I wonder if the root cause of SSRI withdrawal is just your gut microbiome out of whack because of the drugs and takes a long time to normalize

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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End of a week update:

 

Had a lot of symptoms this week, still coming and going:

- GI issues (diarrhea, sharp burning pain, acid reflux)

- Brain fog

- PSSD

- Burning skin in calves and palms

- Muscle weakness - mostly right leg

- Muscle twitching - Right leg, left eye, right triceps

- Right shoulder joint pain

- Major fatigue

- Shaking

- Tinnitus

- Mucus when breathing

 

At the end of the week I'm left with:

- GI issues (improvement in diarrhea, pain is gone)

- Still some minor skin burning

- PSSD

- Still a bit of tingling in palms and feet, mostly gone

- Still get mucus when breathing sometimes

 

I'm still very stressed out by this, really scared of the possibility of staying like this.

Trying to distract myself.

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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On 2/13/2023 at 11:30 AM, BaldPhoenix said:

@peaceandlove What are your symptoms?
Do you have any gut issues?

 

I'm starting to look into gut because my symptoms are always worse when my gut issues are worse.

I also read a lot about PSSD cases on Reddit where they fixed their symptoms by fixing their gut (Dysbiosis / SIBO)

 

Gut issues might just be a symptoms of withdrawal, but I wonder if the root cause of SSRI withdrawal is just your gut microbiome out of whack because of the drugs and takes a long time to normalize


yes I have GI issues which include: constipation, acid reflex , stomach burning pain / cramps. It’s just like my whole digestive system isn’t working pretty much. This is the worse symptom for me. 
 

other symptoms that I’ve had:

 

physical:

fatigue

burning skin feeling

random rashes

heart palpitations 

Frequent urinating / weird sensations down there

 

mental:

intrusive thoughts that aren’t mines

ocd

crying for no reason

scared of stuff I was never afraid of 

depressed feeling

anxiety for no reason

 

I’m pretty much going through the same exact thing as you.

April 2022- Only 1 celxa pill 10mg

had an adverse reaction & never took anymore again 

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  • 2 weeks later...

@BaldPhoenix Hi , I’m also going through something similar as you , after taking one dose of Lexapro 10 mg I have a lot of your symptoms, also the pssd and skin numbness & many more . I also couldn’t believe this could happen to me after one pill . 

December 27, 22’ Lexapro 10mg (only took one dose and immediately stopped) 

(Taking magnesium before bed 11 PM)

 

 

Look to the LORD, and his strength; seek his face always 🙏❤️

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  • 4 weeks later...

Not getting any better unfortunately...

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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  • 5 months later...

Hi all,

I'm not doing any better unfortunately. Many of my symptoms "improved" but were replaced by other symptoms.

 

I am starting to develop severe neuropathy and a neurologist just sent me to get a biopsy for small fiber neuropathy after the rest of my test were clear.

I got the results and they are inconclusive. Not negative but not extremely positive. Not sure what my neurologist will decide to do.

 

I have periods of hearing loss in my right ear (tinnitus and ear pressure), muscle coordination and weakness, blurry vision, nausea, dizziness, PSSD and more.. These symptoms come and go. I actually thought I was doing better until my last 2 flares.

 

It's been 1 year now since I took a single pill of Zoloft, and I'm afraid I've developed autoimmune neuropathy.

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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  • 3 months later...

A little update from me,

 

I was doing a lot better the past 2 months as my joint, muscle, tinnitus, and food sensitivities have improved by a lot.

My eyesight is not blurry anymore. I still have PSSD and shortness of breath.

 

Well unfortunately I ate gluten a few times, and now I have a severe flare up of all my symptoms again. Feel really devastated. I hope it's temporary.

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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  • 2 weeks later...

Doing a lot better, my vision is almost completely recovered, seems like I am getting less waves. A lot less brain fog.

 

No change in sexual symptoms.

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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  • 1 month later...
On 1/12/2024 at 3:57 PM, BaldPhoenix said:

Doing a lot better, my vision is almost completely recovered, seems like I am getting less waves. A lot less brain fog.

 

No change in sexual symptoms.

I also had several issues with my first dose. I don't have pssd but I have reduced sensations in my arms and legs and face.  I haven't had a wave where I have total feeling back. Does your pssd have waves?  You were smart to stop after one dose

Sertaline- tried 50 mg beginning of June 2023. Caused hyperreflexia.  So stopped after one dose. Tried several smaller doses that month.  Had burning and twitching so just stopped. 

Lexapro

June of 2023' 2.5 mg for two weeks 

July of 2023 5 mg for two weeks

July of 2023 7.5 mg for 2 weeks

August to mid September 10 mg

Mid September reduced to 7.5

October to October 15 reduced to 5

October 15 to October 30 reduced to 2.5 

October 30-off

 

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  • 4 weeks later...
On 3/4/2024 at 12:56 AM, Farm24 said:

I also had several issues with my first dose. I don't have pssd but I have reduced sensations in my arms and legs and face.  I haven't had a wave where I have total feeling back. Does your pssd have waves?  You were smart to stop after one dose

Unfortunately I barely have any windows / waves... I had one for a very short period (maybe 30 mins) and then numbness again.

I've accepted this is my new normal... 20 months now. I am getting better but I lost faith that I'm going back to my previous self.

 

And yes I'm glad I didn't listen to the gaslighting.

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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  • 2 weeks later...

20 months now.

 

I am happy to say my vision problems are completely resolved.
My GI issues are a lot better, even though they still exist from time to time.

My erections are starting to return even though I still have genital numbness.

No more numbness of arms and legs.

 

I still have issues, am no where near where I was before being drugged.

 

But I feel some progress. I hope I am starting to turn a corner.

April 2022 - 1/3 of a pill 20mg of paroxetine. Stopped immediately due to sexual dysfunction (recovered 5 days later)

 

August 2022 - 1 pill of 50mg sertraline. Stopped immediately due to sexual dysfunction

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  • 2 weeks later...

How are you doing now? Still

seeing progress? What’s healed and what do you still have? 

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