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okiedoke4: Imipramine Withdrawal Symptoms


okiedoke4

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I quit taking Imipramine in Nov. 2022 but I am still experiencing bad withdrawal effects and its now March 2023. Mainly dizziness, brain fog, unsteadiness and fatique. Anyone else?

Edited by Gridley
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  • Moderator Emeritus

Welcome to SurvivingAntidepressants, okiedoke4.  I was on Imipramine for many years and have been tapering it for the past few years.  The withdrawal symptoms you describe are very typical.

 

To give members the best information, we ask them to summarize their medication history in a signature -- drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly.  A list format, as opposed to a paragraph format, is best. Please include 

--date you started the Imipramine and dose

--any dose changes and dates

--whether you tapered off the drug or stopped cold turkey. If you tapered, date and how fast you tapered

--last dose of the drug you were on before you stopped

--any other psychiatric drugs you were/are taking

 

Account Settings – Create or Edit a signature.

 

We recommend tapering off psychiatric drugs like Imipramine no faster than 10% of your current dose every four weeks.    

 

Why taper by 10% of my dosage?

 

Going off too fast puts you at risk of withdrawal symptoms such as the ones you're experiencing. Withdrawal symptoms 5 months after stopping is very common.

 

What is withdrawal syndrome.

 

Brain Remodelling 

 

Video:  Healing From Antidepressants - Patterns of Recovery

 

Daily Checklist of Antidepressant Withdrawal Symptoms (PDF) 

 

Reinstatement of a very small dose of the original drug is the only known way to help alleviate withdrawal syndrome.  It isn’t a guarantee of diminished symptoms but it’s the best tactic available. The only alternative is to try and wait out the symptoms and manage as best you can until your central nervous system returns to homeostasis.  Unfortunately no one can give you an exact timeline as to when you will start feeling better and while some do recover relatively easily, for others it can take quite a while longer.  

 

Reinstatement predictably works up to 3 months after last dose, so at around 5 months out you're a bit beyond that time frame.  It might work. We usually suggest a much smaller reinstatement dose than your last dose.   Please read:

 

About reinstating and stabilizing to reduce withdrawal symptoms. -- at least the first page of the topic

 

If you're interested in reinstatement, let us know and we can suggest a small reinstatement dose.  For this, we will need the information requested above in your signature. Do not reinstate without letting us suggest a dose--taking too much can destabilize you further.

 

 

We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium (glycinate is a good form) and omega 3 (fish oil). Many people find these to be calming to the nervous system. 

 

 

 

Add in one at a time and at a low dose in case you do experience problems.
 
This is your introduction topic -- the place for you to ask questions, record symptoms, share your progress, and connect with other members of the SA community.  I hope you’ll find the information in the SA forums helpful for your situation.  I'm sorry that you are in the position that you need the information, but I am glad that you found us.

 

 

 
 

 

 
 

 

 

 

 

 

 

 

 

 

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg Valium 

End 2021  year 1 of Valium taper at 6mg

End 2022 year 2 of Valium taper at 2.75mg 

End 2023 year 3 of Valium taper at 1mg

Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper.

Taper is 95% complete.

 

Imipramine 75 mg daily since 1986.  Jan.-Sept. 2016 tapered to 14.4mg  

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5mg and shift to Valium taper

Jan. 24, 2024: Resume Imipramine taper.  Current dose as of Sept 25: 3.6mg

Taper is 95% complete.  

  

Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg, iron, serrapeptase, nattokinase, L-Glutamine, milk thistle, choline


I am not a medical professional and this is not medical advice. It is information based on my own experience as well as that of other members who have survived these drugs.

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  • Gridley changed the title to okiedoke4: Imipramine Withdrawal Symptoms

Hey @okiedoke4 I'm not a mod or anything but I want you to know that we're all here for you, I'm currently 3 and a half months from my last sertraline tablet and am still in withdrawals. Thinking about a small reinstatement. Hope the mods here can give you some good advice and point you in the right direction!

Keep strong

 

SI XX

Previous to pharma I was doing a fair bit of drinking and taking party drugs, mainly from the ages of 18 and 21

2014: started 20mg citalopram

January 2015: switched to sertraline 50mg

March 2017: dropped to 25mg sertraline

Between these last 2 dates I was on and off the sert (now I know this was stupid) 

December 8th 2022: 50mg sertraline (adverse reaction: Suicidal images and homicidal images) 

December 19th 2022: ct from sertaline

Sometime here had a paradoxical reaction to lorazepam (extreme anxiety, closed eye hallucinations) this caused the dpdr to start

February 17th/19th 2023: WD from sertraline started

Also had an amoxicillin treatment in February, not sure if this did anything but I did get akathisia from then

 

"BUT I LOVE THE PAIN, LET IT RAIN AND WASH AWAY, LET IT CARRY YOU TO A BETTER PLACE AND FORGET MY NAME"  Ambleside - Wash away

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  • Moderator Emeritus

 

58 minutes ago, okiedoke4 said:

Imipramine started 25 mgs 1998- was on it for 10 years

Was on 50 mg for 15 years

Stopped cold turkey in Nov. 2022

 

Please use the following link to put this information in your signature.  Then press "save."

 

Account Settings – Create or Edit a signature.

 

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg Valium 

End 2021  year 1 of Valium taper at 6mg

End 2022 year 2 of Valium taper at 2.75mg 

End 2023 year 3 of Valium taper at 1mg

Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper.

Taper is 95% complete.

 

Imipramine 75 mg daily since 1986.  Jan.-Sept. 2016 tapered to 14.4mg  

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5mg and shift to Valium taper

Jan. 24, 2024: Resume Imipramine taper.  Current dose as of Sept 25: 3.6mg

Taper is 95% complete.  

  

Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg, iron, serrapeptase, nattokinase, L-Glutamine, milk thistle, choline


I am not a medical professional and this is not medical advice. It is information based on my own experience as well as that of other members who have survived these drugs.

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  • 3 months later...
On 3/22/2023 at 1:12 PM, okiedoke4 said:

I quit taking Imipramine in Nov. 2022 but I am still experiencing bad withdrawal effects and its now March 2023. Mainly dizziness, brain fog, unsteadiness and fatique. Anyone else?

Are you still around?  I’ve also been on this med for a long time and I’m slowly tapering… wondering how you’re doing.

1994-2002 several different SSRI’s,  klonopin.   
2002 ct klonopin,  2 wks later put back on klonopin, added  Seroquel & lexapro, 

2002 weaned klonopin 2003 weaned off seroquel.  2006 Ct lexapro, six week later added  imipramine 250mg, 2016-2017  imipramine taper 150mg,  2017-2019 100 mg, Jan 2020 50mg, 2 weeks later 60 mg November 2022 56 mg December 2022 50mg 4/5/23 47mg April 2023 40mg june 23,2023 35mg, April 15, 2024 33mg, May 15, 2024 32mg, 5/27/24 30mg, 6/09/24 29mg, 6/14 28mg, 8/2 27mg

Ropinirole 1/2020  3/21 ropinirol 2 mg 

Ozempic 4/2023 .25, 6/26/23 .37mg 12/1/23 .39mg, 4/24 40mg, 5/16/24 .25mg 6/14 0mg

clonidine .1mg 1/2024

Supplements: boron, diatomaceous earth, cream of tartar  and Celtic sea salt, transdermal magnesium oil

 

 

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