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Egle: Polydrugged by doctors with Duloxetine, Cypralex,Valdoxan, Mirtazapin, Flupentixol( antipsychotic), Prozac and diagnosed bipolar on the top


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My story is as follows: since 2012 I was living in constant stress and had huge business and responsibilities. I started to treat my stress by drinking wine. Then I decided to quit meat, and developed anemia. Since my body was weak, I had UTI and various inflammations in kidneys and gut. I was prescribed with antibiotics for 8 months; they totally destroyed my microbiome. Occasionally I was feeling sad from time to time, and at such moments was drinking wine. I know why I started feeling sad, as I was using wine as my coping mechanism to deal with stress, and wine is a big depressant and destroys your microbiome. On 2021 I started having anxiety. I was prescribed with antipsychotic Fluanxol and diagnosed with anxiety disorder and depression. After 3 days anxiety was gone. But after 3month I developed depersonalization and feeling strange like depressed and my doctor said that depression is getting worse and I need SNRI- Cymbalta( duloxetine). I became suicidal and total zombie. After 1,5month she told me to CT, and prescribed Cipralex I developed: anxiety extreme one, vomiting, diarrhea, zombie feeling. After 1,5 month she told me to CT, then I was prescribed valdoxan it did nothing to me. Then I was prescribed mirtazapine, since all the polydruging I developed real depression and anhedonia. On the top they prescribed be Prozac. On Prozac I was getting slightly better, they upped the dose after one year to 60mg and felt even better but anhedonia and dysphoria were never gone.
Now I am tapering mirtazapine since 2023 April, so since April from 45mg to 15mg reached now already. All was good for 2 months( November, December) even anhedonia was gone, but I was not tapering it as I was In Bali. Now when I started tapering again in December, withdrawals started to affect me on 27 January, 3 days bad 4 days good, again 4 days bad 10 days good, now when I reached 15mg I started having panic attacks. Does it sound for you like I have bipolar?
I went to new psychiatrist today as I was feeling very scared of panic attacks and he said all these med did not help you initially as you are BIPOLAR. So now he wants me to prescribe 0lanzapine for 2 months meanwhile to CT mirtazapine and Fluanxol. And then after 2 months to stop olanzapine and Prozac and start lamotrigine. I am going insane, crying nonstop. Can I be Bipolar? Or is it that withdrawals mimic some other illnesses. I don’t feel that I was bipolar before meds I was just sad- and reason was too much wine.
Anxiety was as a side effect of antibiotics in 2021. Please help going insane.

Also what to do I reduced mirtazapine 10% every 3 weeks, now 2 weeks past the last reduction and I am having panic attacks every day and anxiety, depersonalization. Should I wait or should I up dose? Should I slow down with my taper and do 10% every 4-6 weeks?

Please help

Edited by FireflyFyte

2021-January started fluanxol 1mg

Polydrugged with cymbalta, cipralex, valdoxan gabapentin

2021 September started mirtazapine 
2022 January started Fluoxetine 20mg

2022 December upped Fluoxetine to 60mg 

Started tapering 2023April from 45mg Mirtazapine

Currently 2023 April on Mirtazapine 12.5mg

also on Fluoxetine 60mg

Fluanxol 0.5mg 

 

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  • FireflyFyte changed the title to Egle: Polydrugged by doctors with Duloxetine, Cypralex,Valdoxan, Mirtazapin, Flupentixol( antipsychotic), Prozac and diagnosed bipolar on the top
  • Moderator

Hi Egle,

 

Welcome to SA. Please summarize your drug history in your signature by following the instructions at How to Summarize Your Drug History in Your Signature. You may need to be on a computer to complete this.

 

23 hours ago, Egle said:

Now when I started tapering again in December, withdrawals started to affect me on 27 January, 3 days bad 4 days good, again 4 days bad 10 days good,

 

This sounds like The Windows and Waves Pattern of Stabilization.

 

23 hours ago, Egle said:

Does it sound for you like I have bipolar?

 

We have resources dedicated to understanding what is withdrawal at Withdrawal or relapse? Or something else?

 

23 hours ago, Egle said:

Also what to do I reduced mirtazapine 10% every 3 weeks, now 2 weeks past the last reduction and I am having panic attacks every day and anxiety, depersonalization. Should I wait or should I up dose? Should I slow down with my taper and do 10% every 4-6 weeks?

 

While our general guidance is to taper by 10% of the previous dose per month, this proves too fast for some people so it is important to listen to your body. I would consider holding at your current dose to see if you stabilize and then try smaller cuts such as 5%.

 

Thanks,

 

Firefly

 

Pre- October 2022: Wellbutrin, Escitalopram, CitalopramSertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda

Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg

Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022.

Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg

 

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Thank you, I will try to write my shortened story into my signature 

2021-January started fluanxol 1mg

Polydrugged with cymbalta, cipralex, valdoxan gabapentin

2021 September started mirtazapine 
2022 January started Fluoxetine 20mg

2022 December upped Fluoxetine to 60mg 

Started tapering 2023April from 45mg Mirtazapine

Currently 2023 April on Mirtazapine 12.5mg

also on Fluoxetine 60mg

Fluanxol 0.5mg 

 

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  • 1 month later...
On 3/4/2024 at 4:01 PM, FireflyFyte said:

Hi Egle,

 

Welcome to SA. Please summarize your drug history in your signature by following the instructions at How to Summarize Your Drug History in Your Signature. You may need to be on a computer to complete this.

 

 

This sounds like The Windows and Waves Pattern of Stabilization.

 

 

We have resources dedicated to understanding what is withdrawal at Withdrawal or relapse? Or something else?

 

 

While our general guidance is to taper by 10% of the previous dose per month, this proves too fast for some people so it is important to listen to your body. I would consider holding at your current dose to see if you stabilize and then try smaller cuts such as 5%.

 

Thanks,

 

Firefly

I decided to hold on mirtazapine fora while..would like to start tapering fluanxol( flupentixol) i cannot find in SA guides how to taper it.
 

please help  

2021-January started fluanxol 1mg

Polydrugged with cymbalta, cipralex, valdoxan gabapentin

2021 September started mirtazapine 
2022 January started Fluoxetine 20mg

2022 December upped Fluoxetine to 60mg 

Started tapering 2023April from 45mg Mirtazapine

Currently 2023 April on Mirtazapine 12.5mg

also on Fluoxetine 60mg

Fluanxol 0.5mg 

 

Link to comment
  • Moderator
10 minutes ago, Egle said:

would like to start tapering fluanxol( flupentixol) i cannot find in SA guides how to taper it.

 

It does not seem that we have a specific guide for this medication.

 

How are you currently taking the 0.5mg dose? Tablet? Liquid?

 

Pre- October 2022: Wellbutrin, Escitalopram, CitalopramSertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda

Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg

Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022.

Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg

 

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12 hours ago, FireflyFyte said:

 

It does not seem that we have a specific guide for this medication.

 

How are you currently taking the 0.5mg dose? Tablet? Liquid?

its was 1mg coated tablet, I cut in i half. There is no less dose available nor liquid in our pharmacies. I tried to taper it off already 1-0,75-0,5-0,25-0,125 and suffered anxiety, panic attacks, derealization, low mood, insomnia once I got to the point of 0,25mg.

 

2021-January started fluanxol 1mg

Polydrugged with cymbalta, cipralex, valdoxan gabapentin

2021 September started mirtazapine 
2022 January started Fluoxetine 20mg

2022 December upped Fluoxetine to 60mg 

Started tapering 2023April from 45mg Mirtazapine

Currently 2023 April on Mirtazapine 12.5mg

also on Fluoxetine 60mg

Fluanxol 0.5mg 

 

Link to comment
  • Moderator

If you don't already, I would look into getting a scale so you can use it to weigh and measure your doses. You can read more at Using a scale to weigh and measure doses.

 

I am going to do some research to see if you can make a homemade liquid using Fluanxol.

 

Pre- October 2022: Wellbutrin, Escitalopram, CitalopramSertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda

Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg

Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022.

Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg

 

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18 hours ago, FireflyFyte said:

 

It does not seem that we have a specific guide for this medication.

 

How are you currently taking the 0.5mg dose? Tablet? Liquid?

 

2 hours ago, FireflyFyte said:

If you don't already, I would look into getting a scale so you can use it to weigh and measure your doses. You can read more at Using a scale to weigh and measure doses.

 

I am going to do some research to see if you can make a homemade liquid using Fluanxol.

Thank you I will be very thank full to you. As i tried to come off this drug already 3 times, for me its nastier than mirtazapine. 

2021-January started fluanxol 1mg

Polydrugged with cymbalta, cipralex, valdoxan gabapentin

2021 September started mirtazapine 
2022 January started Fluoxetine 20mg

2022 December upped Fluoxetine to 60mg 

Started tapering 2023April from 45mg Mirtazapine

Currently 2023 April on Mirtazapine 12.5mg

also on Fluoxetine 60mg

Fluanxol 0.5mg 

 

Link to comment
On 4/17/2024 at 2:50 PM, FireflyFyte said:

If you don't already, I would look into getting a scale so you can use it to weigh and measure your doses. You can read more at Using a scale to weigh and measure doses.

 

I am going to do some research to see if you can make a homemade liquid using Fluanxol.

Did you find anything on fluanxol? 

2021-January started fluanxol 1mg

Polydrugged with cymbalta, cipralex, valdoxan gabapentin

2021 September started mirtazapine 
2022 January started Fluoxetine 20mg

2022 December upped Fluoxetine to 60mg 

Started tapering 2023April from 45mg Mirtazapine

Currently 2023 April on Mirtazapine 12.5mg

also on Fluoxetine 60mg

Fluanxol 0.5mg 

 

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  • Moderator
4 hours ago, Egle said:

Did you find anything on fluanxol? 

 

I have not been able to isolate any specific information. Can you speak to your doctor to see if a liquid can be compounded?

 

Pre- October 2022: Wellbutrin, Escitalopram, CitalopramSertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda

Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg

Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022.

Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg

 

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