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@PortugueseSea how long did your wave from alcohol last? I ate some rice crackers a few days ago and only realised afterwards that it contained MSG. It must have been a lot of MSG because the crackers triggered a wave of symptoms. I know MSG and alcohol are two different substances, but they both affect the histamine and glutamate baalance in our neurotransmitters. Just wondering how long do waves from food/drinks last. 

Jan 29, 2023 - Took my one and only dose of Mirtazapine (15 mg). Developed an immediate adverse reaction with list of withdrawal-like symptoms.

 

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On rxisk, I read that red wine may help with akathisia. Does anyone here have experience with that? To me alcohol in general seems like a bad idea in withdrawal.

Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg;

Later augmented with quetiapine 75 mg for insomnia;

Cold turkeyed all antidepressants in November 2022;

Currently on:

Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg  (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024)

Diazepam once every week/two weeks, or less frequently

Supplements: magnesium, vit. D3

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Our experience is that alcohol is bad. You can look at the thread here. 

Omw

"Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig 

 

I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. 

 

In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. 

 

Aug  2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg,  xanax prn, wellbutrin for a few months, trazodone prn 

Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used)

Aug 2018 - citalopram 40 mg (self titrated up)

September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0

Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd

March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week

Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering)

citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg,  7/27/19 -1.5 mg,  8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg

 

Supplements: magnesium citrate and bi-glycinate

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3 hours ago, RobertZ said:

On rxisk, I read that red wine may help with akathisia. Does anyone here have experience with that? To me alcohol in general seems like a bad idea in withdrawal.

 

That's coming from this thread - Risk.org - Akathisia

 

Quote

Akathisia sometimes responds to:

 

a benzodiazepine – this is mostly for SSRIs, SNRIs and tricylics

propranolol (beta blocker)

red wine for antipsychotics

 

Alcohol hits GABA in the same way as benzos, so sure, some people may find relief in alcohol. However, that relief is likely short lived and comes with a lot of problems, just like adding in a benzo. Alcohol affects the nervous system and can bring on paradoxical and kindling problems, not to mention creating adverse drug reactions with many psychiatric drugs. 

 

As Onmyway noted, our experience here is that alcohol is bad. It's one thing that can derail a taper for a long time, so please don't look to it as a fix for akathisia (or any other withdrawal symptom). As you noted @RobertZ "alcohol in general seems like a bad idea in withdrawal."

 

A slow taper is the best idea. 

 

 

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On 6/16/2023 at 7:27 AM, Chompoo said:

how long did your wave from alcohol last?


I have never noticed a wave that I definitely traced to alcohol. As I mentioned, I definitely did react to dessert wine. In those cases I promptly went back to baseline the next day.

When I was over in Portugal (now I am back to Japan) I indulged in red wine frequently, just one or two glasses at the time. To be honest, and despite what David Healey stated in the link @Shep shared, I never experienced any benzo-like relief from it. Neither did I notice a worsening.

That article in particular terrifies me, for a different reason, this:

"In a proportion of those who have been on antidepressants or antipsychotics for a long time, it may take several months or more after discontinuation of the drug for the akathisia to wear off. For some, a residual amount may persist indefinitely, leaving the person unable to feel completely relaxed or emotionally content."

I keep asking myself how long "for a long time" means. 

Urgh.




I am now trying to avoid alcohol altogether, which is hard due to my job. Maybe I will notice more windows and or shallower waves?

Bless

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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@PortugueseSea thanks for letting me know. Great your bad reaction to alcohol went away the next day. My reaction to MSG took several days to subside, but I might have worsened it by (i) taking some GABA supplements for sleep and (ii) overexerting myself packing for a home move.

I hope your akathisia will go away soon. All the best!

Jan 29, 2023 - Took my one and only dose of Mirtazapine (15 mg). Developed an immediate adverse reaction with list of withdrawal-like symptoms.

 

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@Chompoo thanks man. I am working on more systematic symptom and well being charting. I will start posting them on my introduction thread. I hope that will help me figure out patterns. If you guys can see a connection between my sparse alcohol consumption and symptoms that would be even a bigger incentive to stop altogether. I am working on it and have cut consumption substantially. Tough for a born and bred south European.

I have noticed waves following difficult conversations with my parents, I have also noticed waves after lack of sleep. That is pretty much it.

While tapering the Mirtazapine I did feel quite agitated at times after each cut. That is gone, thank God. 

My most distressing symptoms are 1) somatic discomfort, 2) Neck and Head pressure, heaviness, or piercing sensations, 3)neuro-emotions, mostly in the form of terror. 
I equate the akathisia with all the three symptoms, though I guess I could be wrong.

Bless.

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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@PortugueseSea I'm a woman. It might be a good idea to cut out alcohol totally for at least a few months. Indeed, very little can trigger waves when we're in withdrawals, including difficult conversations and lack of sleep. How much sleep are you having these days? My bad reaction to the rice crackers is still causing me sleep problems and symptoms 6 days later. I had 8 pieces of the crackers but there was enough MSG in them to cause such a bad wave.

Jan 29, 2023 - Took my one and only dose of Mirtazapine (15 mg). Developed an immediate adverse reaction with list of withdrawal-like symptoms.

 

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On 6/18/2023 at 10:13 AM, Chompoo said:

 I'm a woman.

Very sorry xD

 

On 6/18/2023 at 10:13 AM, Chompoo said:

Indeed, very little can trigger waves when we're in withdrawals, including difficult conversations and lack of sleep.


It's funny you have just posted this because I think I have been able to confirm a definite reaction to alcohol for the first time!

 

 

On 6/18/2023 at 10:13 AM, Chompoo said:

My bad reaction to the rice crackers is still causing me sleep problems and symptoms 6 days later.

The rice cracker stuff is crazy, how sensitive can we be? I hope you feel better soon! I myself indulged in some cold meats and brie cheese tonight and it seems to have caused a slight worsening? Probably histamine I guess?

It is such a slow learning curve!

 

 

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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@PortugueseSea no worries on mistaking me for a man.

How did you confirm a definite reaction to alcohol for the first time?

Cold meats and brie cheese are high histamine food. Best to avoid them.

I prolonged my wave from the rice crackers by taking supplements to lessen the symptoms. In the end, they made me worse and I'm still suffering 8 days later. I'm the Queen of Self-Sabotage, haha.

Jan 29, 2023 - Took my one and only dose of Mirtazapine (15 mg). Developed an immediate adverse reaction with list of withdrawal-like symptoms.

 

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Thanks!

 

On 6/20/2023 at 7:01 PM, Chompoo said:

How did you confirm a definite reaction to alcohol for the first time?


I basically had a temporary worsening that cleared after a couple days right after an evening when I ingested alcohol.

 

As of now, the only things I have confirmed trigger a wave are lack of sleep, magnesium glycinate and alcohol (generally more than a drink or two).

I am back into wave territory now after two or three days of poor sleep. Was doing pretty well for three or four days. I will post my notes on my introduction, you can check it out there =)

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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  • 1 month later...

@brassmonkey I saw your comment on here from 2015 regarding setbacks. I was stabilized on a Prozac dose for 4 years after re-instating. I have been drinking socially for the past couple of months as I thought I was healed. I’m currently experiencing acute withdrawal symptoms now for 3 weeks and having some really good windows but following them are very bad waves. Will I ever stabilize again? I’m so incredibly upset I did this to myself. 

2010- Celexa 20 mg

2012-lexapro 20mg 

2015- lexapro 30mg

October 2016- tried a too fast taper of lexapro and completely crashed. I reinstated 10mg after 3 months and it worked.

December 2016- started to wean off lexapro with liquid and got off in April of 2018 

got pregnant in June of 2018 and remained off lexapro no withdrawal symptoms.

february 2019- right after I gave birth I started having withdrawal symptoms 

March 2019- reinstated 10mg lexapro, it made me very sick

May 2019- did a successful Prozac bridge and immediately felt better.

currently stabilized on 20mg Prozac 

 

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@This2shallpass you're going to have to wait until your nervous system settles down, sorry to say.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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  • 5 months later...

Hi,

 

im just wondering if anyone has been in a similar. Situation that I can speak with. I was stable for 3 years on Prozac after a reinstatement. In Jan 2023 I started drinking pretty heavily every weekend. In July 2023 I crashed and started experiencing acute symptoms again. It’s now been 7 months.  Does anyone know why it took so long for my nervous system to react? I was fine drinking for months. Also it seems people recover rather quickly from alcohol setbacks but I’m still struggling. Any thoughts? 
 

fyi- I stopped drinking and will never touch alcohol again. 

2010- Celexa 20 mg

2012-lexapro 20mg 

2015- lexapro 30mg

October 2016- tried a too fast taper of lexapro and completely crashed. I reinstated 10mg after 3 months and it worked.

December 2016- started to wean off lexapro with liquid and got off in April of 2018 

got pregnant in June of 2018 and remained off lexapro no withdrawal symptoms.

february 2019- right after I gave birth I started having withdrawal symptoms 

March 2019- reinstated 10mg lexapro, it made me very sick

May 2019- did a successful Prozac bridge and immediately felt better.

currently stabilized on 20mg Prozac 

 

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On 1/19/2024 at 9:50 PM, This2shallpass said:

Does anyone know why it took so long for my nervous system to react? I was fine drinking for months.


As our nervous system recovers, it can deal with more destabilizing factors, alcohol being one of them. By drinking heavily every weekend for months you slowly overwhelmed it.
It should settle, have you noticed any improvements during these 7 months?

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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On 1/19/2024 at 1:50 PM, This2shallpass said:

Also it seems people recover rather quickly from alcohol setbacks

Hi! 

I don't know what lead u to this comment but that's not true. I crashed 2 times from alc and it's still ongoing for nearly 2 years now. I felt some reliefs but at least it destroyed me more and I am in a Worse situation then I was before. Sadly to say. But this It doesn't have to be ur story. Wish u the best. 

09/2018 Quetiapin 100 mg 8 weeks 

10/2018 Prozac 20 mg 2 weeks 

05/2019 - 10/2019 abilify 2.5 mg

12/2019-03/2020 Moclobemid 600

01/2020 - 04/2020 Lithium 1125

03/2020 8 ketamin injections

05/2020 drug free 

11/2020 lots of improvements 

12/2020 cigs crash, huge setback 

07/2021 a bit better but far from my state in autumn 2020

01/2024 I crashed again 2022. I live an disabled life and start to think it's forever 

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Thank you @PortugueseSea, yes I’ve seen lots of improvements. The waves are not as intense, and the severe burning skin and restlessness is not as often.  What you stated makes sense I appreciate your response. 

2010- Celexa 20 mg

2012-lexapro 20mg 

2015- lexapro 30mg

October 2016- tried a too fast taper of lexapro and completely crashed. I reinstated 10mg after 3 months and it worked.

December 2016- started to wean off lexapro with liquid and got off in April of 2018 

got pregnant in June of 2018 and remained off lexapro no withdrawal symptoms.

february 2019- right after I gave birth I started having withdrawal symptoms 

March 2019- reinstated 10mg lexapro, it made me very sick

May 2019- did a successful Prozac bridge and immediately felt better.

currently stabilized on 20mg Prozac 

 

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On 1/25/2024 at 4:04 PM, Driksdog said:

I crashed 2 times from alc and it's still ongoing for nearly 2 years now. I felt some reliefs but at least it destroyed me more and I am in a Worse situation then I was before. Sadly to say. But this It doesn't have to be ur story. Wish u the best. 


If you look around the thread, most crashes from alcohol fade within six months, in many cases in a couple weeks. Do not lose hope man, if you find alcohol affects you really badly stay off. You can still improve, our bodies know what to do to heal. I am sure you will recover in due time!

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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6 hours ago, This2shallpass said:

Thank you @PortugueseSea, yes I’ve seen lots of improvements. The waves are not as intense, and the severe burning skin and restlessness is not as often.  What you stated makes sense I appreciate your response. 


No problem, I know it is hard to stay optimism with this much suffering. I am living through the same, my waves are less intense, I am much more functional but... this still sucks bad...

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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It really is @PortugueseSea but we have to hang on. I just cant find anyone in my situation who was stable for so long so it’s discouraging and makes me think I may have something else going on or I’m the one who don’t heal and I damaged myself beyond repair. I wish you continued healing! 

2010- Celexa 20 mg

2012-lexapro 20mg 

2015- lexapro 30mg

October 2016- tried a too fast taper of lexapro and completely crashed. I reinstated 10mg after 3 months and it worked.

December 2016- started to wean off lexapro with liquid and got off in April of 2018 

got pregnant in June of 2018 and remained off lexapro no withdrawal symptoms.

february 2019- right after I gave birth I started having withdrawal symptoms 

March 2019- reinstated 10mg lexapro, it made me very sick

May 2019- did a successful Prozac bridge and immediately felt better.

currently stabilized on 20mg Prozac 

 

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On 1/25/2024 at 2:04 AM, Driksdog said:

Hi! 

I don't know what lead u to this comment but that's not true. I crashed 2 times from alc and it's still ongoing for nearly 2 years now. I felt some reliefs but at least it destroyed me more and I am in a Worse situation then I was before. Sadly to say. But this It doesn't have to be ur story. Wish u the best. 

 
were you stable for years prior to your setback? I was stable for 3 years. 

2010- Celexa 20 mg

2012-lexapro 20mg 

2015- lexapro 30mg

October 2016- tried a too fast taper of lexapro and completely crashed. I reinstated 10mg after 3 months and it worked.

December 2016- started to wean off lexapro with liquid and got off in April of 2018 

got pregnant in June of 2018 and remained off lexapro no withdrawal symptoms.

february 2019- right after I gave birth I started having withdrawal symptoms 

March 2019- reinstated 10mg lexapro, it made me very sick

May 2019- did a successful Prozac bridge and immediately felt better.

currently stabilized on 20mg Prozac 

 

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I was never really stable on that shxx pill stuff. I had direct adverse reactions. I was stable in healing after cold turkey it. Then I drunk and crashed with old and new symptoms. Now I really fell like it's a damage beyond repair. I wake up every morning with an hangover like after a extremely drunken night, I got headpressure and headaches, feel weak like an 80 year old man, aphatic... Etc.  

I am out of pills since 2020 and the last crash was 2022 in February. So yes I think I am destroyed and no there is no stability in my life. Wish u it would better for u. BTW I took Prozac 20mg for 16 days. This was the biggest mistake in my life. 

09/2018 Quetiapin 100 mg 8 weeks 

10/2018 Prozac 20 mg 2 weeks 

05/2019 - 10/2019 abilify 2.5 mg

12/2019-03/2020 Moclobemid 600

01/2020 - 04/2020 Lithium 1125

03/2020 8 ketamin injections

05/2020 drug free 

11/2020 lots of improvements 

12/2020 cigs crash, huge setback 

07/2021 a bit better but far from my state in autumn 2020

01/2024 I crashed again 2022. I live an disabled life and start to think it's forever 

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  • 2 weeks later...

@Driksdog, I am sorry to hear that. 
I also suffer from the same symptoms you mentioned.

Hope it gets better for both of us.

Had an immediate adverse reaction from the first two doses.

 

9/22 Agotine 25mg, Abilify 1mg, Topiramate 25mg

9/26 Agotine 50mg, Abilify 2mg, Topiramate 50mg

10/12 Agotine 50mg, Abilify 2mg, Risperidone 0.5mg, Topiramate 50mg

10/20 Agotine 50mg, Abilify 3mg, Topiramate 50mg, Risperidone 0.5mg 1/2

10/23 Agotine 50mg, Abilify 3mg, Topiramate 50mg

10/30 Agotine 25mg, Abilify 1mg, Topiramate 25mg - Cold turkey after this

11/13 Abilify 1mg, Escitalopram 5mg - Only single dose

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3 minutes ago, KaiLee said:

@Driksdog, I am sorry to hear that. 
I also suffer from the symptoms you mentioned.

Hope it gets better for both of us.

Thanx! Wish u the best. 

09/2018 Quetiapin 100 mg 8 weeks 

10/2018 Prozac 20 mg 2 weeks 

05/2019 - 10/2019 abilify 2.5 mg

12/2019-03/2020 Moclobemid 600

01/2020 - 04/2020 Lithium 1125

03/2020 8 ketamin injections

05/2020 drug free 

11/2020 lots of improvements 

12/2020 cigs crash, huge setback 

07/2021 a bit better but far from my state in autumn 2020

01/2024 I crashed again 2022. I live an disabled life and start to think it's forever 

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The brutal truth is that - even for healthy people not going through withdrawal - there is absolutely no safe amount of alcohol. It's a drug that does not have any health benefits whatsoever, only negative consequences.

 

My therapist summed it up when she said alcohol is 'a liquid benzodiazepine', and would I 'think it was okay to pop a few valium several times a week to relax'.

 

Like antidepressants, alcohol rewires the brain, in this case causing it to reduce the natural production of neurotransmitters like dopamine and GABA, which are vital for well-being and controlling anxiety. On top of that it damages the gut, further reducing the availability of serotonin, as well as preventing the absorption of vital nutrients. (Alcohol can also kill probiotics, so people taking them while drinking are often wasting their money).

 

And like antidepressants, these changes to the brain are long-term. It often takes several months, or years, of no alcohol for the brain to recover and restore natural levels of neurotransmitters.

 

This damage doesn't just apply to the stereotypical 'alcoholic' either, drinking at or around the maximum recommended number of units per week regularly will cause damage.

 

That's around 12-14 units (1.5 bottles of wine), in a 7-day period. Most people probably aren't aware that anything over that is classed as heavy drinking.

 

So for those of us in withdrawal, any alcohol really is pouring fuel onto the fire, putting extra stress on a brain and body that's already dealing with a huge amount.

 

My therapist also said she thinks it's ludicrous that people are put on antidepressants without even being asked about their alcohol and caffeine consumption - as she's had patients who've cut out both completely and found their issues with depression and anxiety have improved considerably. Even those who think they consume relatively small amounts have benefitted.

Oct 2018 - Jun 2020: 10 mg per day generic Escitalopram in pill form.

Jul 2020 - Aug 2020: Switched to 9 mg per day of Cipralex drops to aid tapering.

Sep 2020 - Oct 2020: Taper to 8 mg.

Nov 2020 - Dec 2020: Taper to 7 mg.

Jan 2021 - Feb 2021: Taper to 6 mg.

Mar 2021 - Apr 2021: Taper to 5 mg.

May 2021 - Jun 2021: Taper to 4 mg.

Jul 2021 - Sep 2021: Taper to 3 mg.

Sep 2021 - Jan 2022: Taper to 2 mg.

Jan 2022: Stopped taking altogether.

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Well, this was a good Summary about that stuff. I don't drink any alcohol for 2 years now. Also no other drugs or meds. 

U are right with all u saying about it. It's an neurotoxin and lots of ppl use it without any doubts. 

At least I have to say... I also used it in the past alot and I had my problems with it. But it never destroyed me like psycho pills. Ending with DP, aphaty, sexual issues....! I never felt like I lost my soul. That's for me for over 3 years now. 

09/2018 Quetiapin 100 mg 8 weeks 

10/2018 Prozac 20 mg 2 weeks 

05/2019 - 10/2019 abilify 2.5 mg

12/2019-03/2020 Moclobemid 600

01/2020 - 04/2020 Lithium 1125

03/2020 8 ketamin injections

05/2020 drug free 

11/2020 lots of improvements 

12/2020 cigs crash, huge setback 

07/2021 a bit better but far from my state in autumn 2020

01/2024 I crashed again 2022. I live an disabled life and start to think it's forever 

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13 hours ago, jon1 said:

My therapist also said she thinks it's ludicrous that people are put on antidepressants without even being asked about their alcohol and caffeine consumption - as she's had patients who've cut out both completely and found their issues with depression and anxiety have improved considerably. Even those who think they consume relatively small amounts have benefitted.


Very well put, I have completely come off coffee and I think it has helped. I am going to, sadly, give up chocolate. It might just be that even that is worsening my activation.

 

As for alcohol, now I rarely drink. But that rarely should be 0. I think it has caused me setbacks once or twice. As you mentioned, it does not help the brain whatsoever, it is negative escapism plain and simple.

That said, @Driksdog, @KaiLee, @This2shallpass, despair is not allowed. A setback is a setback, no matter how bad it is. The body has the ability to heal. Use it as a chance to improve your life habits and move forward!

We are all in this together!

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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Thank you @PortugueseSea I appreciate that! I’m trying to stay positive, but I’m getting brain zaps now. I don’t know if I’m in poop out or in a setback. I’m really panicking. 

2010- Celexa 20 mg

2012-lexapro 20mg 

2015- lexapro 30mg

October 2016- tried a too fast taper of lexapro and completely crashed. I reinstated 10mg after 3 months and it worked.

December 2016- started to wean off lexapro with liquid and got off in April of 2018 

got pregnant in June of 2018 and remained off lexapro no withdrawal symptoms.

february 2019- right after I gave birth I started having withdrawal symptoms 

March 2019- reinstated 10mg lexapro, it made me very sick

May 2019- did a successful Prozac bridge and immediately felt better.

currently stabilized on 20mg Prozac 

 

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So, do u guys think I should also quit coffee? I still drink it. I know it is an stimulant. It gives me more Stomach acid. Maybe it also holds me back and gives me symptoms!? 

09/2018 Quetiapin 100 mg 8 weeks 

10/2018 Prozac 20 mg 2 weeks 

05/2019 - 10/2019 abilify 2.5 mg

12/2019-03/2020 Moclobemid 600

01/2020 - 04/2020 Lithium 1125

03/2020 8 ketamin injections

05/2020 drug free 

11/2020 lots of improvements 

12/2020 cigs crash, huge setback 

07/2021 a bit better but far from my state in autumn 2020

01/2024 I crashed again 2022. I live an disabled life and start to think it's forever 

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39 minutes ago, Driksdog said:

So, do u guys think I should also quit coffee? I still drink it. I know it is an stimulant. It gives me more Stomach acid. Maybe it also holds me back and gives me symptoms!? 

 

If you're suffering from issues, it's probably a good idea. I quit all caffeine (coffee, tea, diet drinks, and chocolate) just over six months ago, and while it was very difficult in the beginning, it's made a definite difference to my levels of anxiety and my sleep is much, much better.

 

As an added bonus, my acid reflux is pretty much gone, and my blood pressure dropped considerably.

 

Caffeine doubles the amount of stress hormones, like cortisol and adrenaline, in the blood. Those levels stay raised for up to 24 hours, even after only one cup. Meanwhile, the 'good feeling' - the initial dopamine hit - only lasts around 30 minutes.

 

It seems like SSRI withdrawal compromises our body's ability to 'mop up' stress hormones, so they hang around for a lot longer and at higher levels than they normally would.

 

Unfortunately, an awful lot of people around the world are on the 'caffeine in the morning as an upper, alcohol in the evening to relax' cycle, without even realising the issues it causes.

Oct 2018 - Jun 2020: 10 mg per day generic Escitalopram in pill form.

Jul 2020 - Aug 2020: Switched to 9 mg per day of Cipralex drops to aid tapering.

Sep 2020 - Oct 2020: Taper to 8 mg.

Nov 2020 - Dec 2020: Taper to 7 mg.

Jan 2021 - Feb 2021: Taper to 6 mg.

Mar 2021 - Apr 2021: Taper to 5 mg.

May 2021 - Jun 2021: Taper to 4 mg.

Jul 2021 - Sep 2021: Taper to 3 mg.

Sep 2021 - Jan 2022: Taper to 2 mg.

Jan 2022: Stopped taking altogether.

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35 minutes ago, Driksdog said:

So, do u guys think I should also quit coffee? I still drink it. I know it is an stimulant. It gives me more Stomach acid. Maybe it also holds me back and gives me symptoms!? 

In my experience, coffee is worst than alcohol if you suffer from activation, akathisia, or nervousness.

I am going to give up chocolate too, unfortunately.

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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6 hours ago, This2shallpass said:

Thank you @PortugueseSea I appreciate that! I’m trying to stay positive, but I’m getting brain zaps now. I don’t know if I’m in poop out or in a setback. I’m really panicking. 

You are welcome! Either way, your way is down. Stabilize and drop. You know the drill!

Hang in there!

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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5 hours ago, PortugueseSea said:

In my experience, coffee is worst than alcohol if you suffer from activation, akathisia, or nervousness.

I am going to give up chocolate too, unfortunately.

Hey! No I am mostly flat like a pancake. No anxiety, no panic, nearly no emotions. Even the good once are gone. Only some grief is left. So coffee feels like nothing. My system feels like dead. Weakness, no power.... Headaches, burning neck an back. 

09/2018 Quetiapin 100 mg 8 weeks 

10/2018 Prozac 20 mg 2 weeks 

05/2019 - 10/2019 abilify 2.5 mg

12/2019-03/2020 Moclobemid 600

01/2020 - 04/2020 Lithium 1125

03/2020 8 ketamin injections

05/2020 drug free 

11/2020 lots of improvements 

12/2020 cigs crash, huge setback 

07/2021 a bit better but far from my state in autumn 2020

01/2024 I crashed again 2022. I live an disabled life and start to think it's forever 

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  • 2 weeks later...
On 2/10/2024 at 9:29 PM, Driksdog said:

Hey! No I am mostly flat like a pancake. No anxiety, no panic, nearly no emotions. Even the good once are gone. Only some grief is left. So coffee feels like nothing. My system feels like dead. Weakness, no power.... Headaches, burning neck an back. 

If you do not feel any negative reaction from coffee it means it is okay for you.

Yeah, burning neck, I have that one on and off, it has been improving lately but it still is such a pain...

December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN.

March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg).

April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol.

May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).
June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). 
September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.
March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound.

May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. 
June 2023 - Added fish oil.
Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2
Intro thread: 
https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/

 

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Hi! 

Yes it's unbearable. Skin sensitivity is pretty high. Often clothes feel like they are made out of sandpaper. I try to where things which are mostly Smooth and aren't Rough Woven. Something like jackets with teddy Fabric inside it's pure pain in my back. Same time sound sensitivity is the highest. Smallest Noises are hurt like shxx. Feels like it comes from front loop, goes to the neck down to my back. I guess it's gluta imbalance. I remember having something similar but far lighter and short while before pills when I got Chinese food. It contains Flavor acting on gluta. Now it's every day stuff for me. 

09/2018 Quetiapin 100 mg 8 weeks 

10/2018 Prozac 20 mg 2 weeks 

05/2019 - 10/2019 abilify 2.5 mg

12/2019-03/2020 Moclobemid 600

01/2020 - 04/2020 Lithium 1125

03/2020 8 ketamin injections

05/2020 drug free 

11/2020 lots of improvements 

12/2020 cigs crash, huge setback 

07/2021 a bit better but far from my state in autumn 2020

01/2024 I crashed again 2022. I live an disabled life and start to think it's forever 

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Hi @Driksdog

 

I have just read your signature and it says that your last crash was in 2022. Do you know what caused it?

 

Started 10mg escitalopram March 2016 and stopped CT Feb 2017.

Started 10mg citalopram May 2019

Swapped with mirtazapine mid June 2019 used for a week and then switched to Escitalopram 5mg at the end of July 2019, increased gradually to 10mg in September, 15mg in October and 20mg in January 2020. Tapered down to 15mg in April. 10mg in June then a week tapering to 5mg and then stopped CT. 
Resumed escitalopram in November 2020 at 5mg, increased to 10mg in February 2021, tapered down to 5mg in May 2021 and tapered down to 2.5 in the space of a week in September 2021. Resumed escitalopram at the end of December 2022 at 5mg, increased it to 10mg in March 2023 then tapered down to 5mg in June and down to 2.5mg in July. Started escitalopram 5mg beginning of December 2023 then stopped after 4 days. Took amytryptamine for 2 days then restarted escitalopram at 5mg, after two weeks increased it to 7.5mg, kept it for 1 week then 10mg for 1 week but two many side effects so went back to 5mg. Beginning of January 2023 stopped escitalopram for 1 day then 2.5mg for the next day. Developed  discontinuation symptoms reinstated it at 2.5 for 1 week and 1.5 for the following week then stopped. I’m currently experiencing withdrawal symptoms.

 

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