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CeruleanSea

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Feeling concerned today. I’m having more word finding problems and slight memory problems. I have experienced this before with c/t, and with greater reductions. In fact I reinstated fully from 37.5 in fall 2021 because of similar effects. 

 

This is so concerning plus embarrassing as a working professional. 
 

This time I’m not going to reinstate. I’m planning to take this month’s  reduction slower. I had reduced another 10% of my current dose. I’m planning for the rest of the month to reduce 5% from where I was on March 1 & stay there. From 45 to 42.75 instead of 40.5. 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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I’m having such brain fog!! This is frustrating & concerning. I feel like I never healed from c/t years & years ago.  Ever since then my thinking has not been 100%.  I’ve even had neuropsych testing and it showed a lower than average attention span but really great long-term memory. Now I would say to my attention span and working memory that are affected. 
 

what to do? I’m also working through other possible health concerns to see if anything else could be contributing to this symptom. So far everything has been normal.

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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Hi @CeruleanSea

 

I'm sorry the fog and attention span is bad. It’s hard isn’t it.

 

My attention span and brain fog has been absolutely terrible since I started the meds. I thought it was the trauma that had done that but I know now it’s the meds. 
I have short periods when I can concentrate and have amazing attention to detail and then days when I can only concentrate long enough to answer e-mails and do basic admin.  I think it’s partly attention span but I think It’s also partly that some days I just couldn’t care much about anything.  I wish I could turn the clock back sometimes.

Sertraline (Lustral):  2014. Sept 50mg. Oct 100mg. Dec 150mg. 2015-2019. 150mg. 2019  Apr-May 0mg. Beg May 150mg. End May 100mg. Late June 125mg. Late Aug 100mg. 2020 Jan 75mg. April 50mg.

2022  50mg. 1Jan 45mg. 1Feb 40.5mg. Water T24Feb 39.5mg. 3Mar 38.5mg. 18Mar 38mg. 25Mar 37.5mg. 22Apr 37mg. 5May 36.5mg. 18May 36mg. 1Jun 35.3mg. 15Jun 34.5mg.  30Jun 34mg. 15Jul 33.5mg. 22Jul 33mg. 5Aug 32.5mg. 19Aug 32mg. 1Sept 31.5mg. 1Oct 31mg.  27 Oct 30.5. 16 Nov 30mg. 30 Nov 29.5mg. 14 Dec 29mg

2023. 2 Jan 28.5mg. 6 Feb 28mg. 10 Mar 27.5mg. 1 Apr 26.5mg. 1 May 26mg. 1 Jun 25.5mg. 1 Jul 25mg. 1 Aug 24.5mg. 17 Aug 24mg. 5 Sept 23.5mg. 9 Oct 23mg.

 

Desogestrel:  2014 -  present:  

Supplements Magnesium. 400mcg  Vitamin D. 10mcg.  Multivit/min. 1 tab. B Complex

 

Certirizine:   2022 May 10mg. Dec 20mg. 2023. 15mg.

 Omeprazole.:  2016 20mg. 2022  20mg.  15Jan 15mg. 9Feb 10mg. 25Feb 6.5mg. 15Mar 3mg. 3Apr 1.5mg.  15Apr 0mg   2023. 20mg. 15 Sept 15mg.

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Over the last week, I’ve been starting to feel great! My brain fog fell away.  I’ve been feeling more motivated & optimistic.  
 

At the same time, I’ve been having insomnia with unrefreshing sleep for a couple of days. It may be that my bad coffee habit contributes to this.

 

I’ve mentioned this before, but I’ve often drank 2-3 cups of coffee daily to manage my ssri fatigue.. ️ It’s the only real addiction I’ve had in life, but it’s there. And I’m guessing I’ve got to cut out that third cup now.  
 

 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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Oh that's brilliant @CeruleanSea

The insomnia not so great.  Could you switch to decaf?    Maybe start with decaf for the 3rd cup?

 

I love coffee but I developed an allergy to caffeine so I'd get hives all over my face.   I switched to decaf as I can tolerate that, so I still get to have my lovely coffee on a morning.

Sertraline (Lustral):  2014. Sept 50mg. Oct 100mg. Dec 150mg. 2015-2019. 150mg. 2019  Apr-May 0mg. Beg May 150mg. End May 100mg. Late June 125mg. Late Aug 100mg. 2020 Jan 75mg. April 50mg.

2022  50mg. 1Jan 45mg. 1Feb 40.5mg. Water T24Feb 39.5mg. 3Mar 38.5mg. 18Mar 38mg. 25Mar 37.5mg. 22Apr 37mg. 5May 36.5mg. 18May 36mg. 1Jun 35.3mg. 15Jun 34.5mg.  30Jun 34mg. 15Jul 33.5mg. 22Jul 33mg. 5Aug 32.5mg. 19Aug 32mg. 1Sept 31.5mg. 1Oct 31mg.  27 Oct 30.5. 16 Nov 30mg. 30 Nov 29.5mg. 14 Dec 29mg

2023. 2 Jan 28.5mg. 6 Feb 28mg. 10 Mar 27.5mg. 1 Apr 26.5mg. 1 May 26mg. 1 Jun 25.5mg. 1 Jul 25mg. 1 Aug 24.5mg. 17 Aug 24mg. 5 Sept 23.5mg. 9 Oct 23mg.

 

Desogestrel:  2014 -  present:  

Supplements Magnesium. 400mcg  Vitamin D. 10mcg.  Multivit/min. 1 tab. B Complex

 

Certirizine:   2022 May 10mg. Dec 20mg. 2023. 15mg.

 Omeprazole.:  2016 20mg. 2022  20mg.  15Jan 15mg. 9Feb 10mg. 25Feb 6.5mg. 15Mar 3mg. 3Apr 1.5mg.  15Apr 0mg   2023. 20mg. 15 Sept 15mg.

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I noticed yesterday that I felt unusually nervous when speaking with a group.  I was meeting a group of people for the first time at my child's school.  This nervousness is to be expected somewhat, but it was also after I had a big cup of delicious Starbucks coffee.    

 

I can see now that the coffee really contributes to my anxiety AND possibly insomnia.  The habit really did take hold on sertraline, as it gives me a bit of fatigue.  

 

On 3/16/2022 at 3:22 AM, Blossom71 said:

The insomnia not so great.  Could you switch to decaf?    Maybe start with decaf for the 3rd cup?

 

@Blossom71, I like the suggestion to make my third cup decaf.  I'm looking into that or into switching to green tea for the third cup.  

 

 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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I should be thinking one day at a time, but I'm already thinking about my taper for April 2022.  Cutting down another 10% would bring me to 36.45.  But I'm planning to reduce to 37.5 so I can just use the tablets I am already prescribed.  Cutting one 25 mg pill in half creates 12.5 mg, and my pills are scored.  Just one month of not worrying over dissolving, measuring reductions.

 

In the past, 37.5 is when I start to feel more brain fog, memory and word-finding issues, and more panicky.   Thinking over how to manage those symptoms.   Obviously less caffeine is part of it.

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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I am feeling so motivated today!  Better focus than in a long time, especially on full dose meds.    

 

When I began, I complained to my doctor about lower motivation.  I'm already starting to see more after 1-1/2 months of reductions.

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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Whoops, I feel I’ve backslid. I was ill with bad headaches on Monday night & took my whole 50 mg dose thoughtlessly.
 

Tuesday I was amazingly motivated & focused! I was clever with jokes when conversing…Wednesday on a regular dose I just felt so blah & unmotivated & foggy.

 

Staying the course but wishing I could have it all.

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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I'm noticing that I am absurdly hungry on the higher dose of sertaline.   Maybe I was always this hungry on it and did not know?

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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I had a horrible day-long headache both Wednesday and Thursday.  Migraine-like symptoms, light sensitivity, poor thinking.  I'm planning to arrange a check-up with my family doctor, as I'm starting to suspect there may be more going on than just ssri withdrawal with these frequent headaches.  

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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Sorry you're not feeling too great @CeruleanSea

 

I\'ve been a bit up and down this week but instead of taking a higher dose by accident I forgot mine 🙄

Hope you get you headaches sorted.   I do rarely get headaches but they've definitely been more frequent since i started dropping.  I hope it's just that and nothing else x

Sertraline (Lustral):  2014. Sept 50mg. Oct 100mg. Dec 150mg. 2015-2019. 150mg. 2019  Apr-May 0mg. Beg May 150mg. End May 100mg. Late June 125mg. Late Aug 100mg. 2020 Jan 75mg. April 50mg.

2022  50mg. 1Jan 45mg. 1Feb 40.5mg. Water T24Feb 39.5mg. 3Mar 38.5mg. 18Mar 38mg. 25Mar 37.5mg. 22Apr 37mg. 5May 36.5mg. 18May 36mg. 1Jun 35.3mg. 15Jun 34.5mg.  30Jun 34mg. 15Jul 33.5mg. 22Jul 33mg. 5Aug 32.5mg. 19Aug 32mg. 1Sept 31.5mg. 1Oct 31mg.  27 Oct 30.5. 16 Nov 30mg. 30 Nov 29.5mg. 14 Dec 29mg

2023. 2 Jan 28.5mg. 6 Feb 28mg. 10 Mar 27.5mg. 1 Apr 26.5mg. 1 May 26mg. 1 Jun 25.5mg. 1 Jul 25mg. 1 Aug 24.5mg. 17 Aug 24mg. 5 Sept 23.5mg. 9 Oct 23mg.

 

Desogestrel:  2014 -  present:  

Supplements Magnesium. 400mcg  Vitamin D. 10mcg.  Multivit/min. 1 tab. B Complex

 

Certirizine:   2022 May 10mg. Dec 20mg. 2023. 15mg.

 Omeprazole.:  2016 20mg. 2022  20mg.  15Jan 15mg. 9Feb 10mg. 25Feb 6.5mg. 15Mar 3mg. 3Apr 1.5mg.  15Apr 0mg   2023. 20mg. 15 Sept 15mg.

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After a couple of nights of taking a full dose due to a hectic schedule & missing dropper, I dropped to 37.5 in order to have an easier dose for now. This is approximately an 8% drop, and I think good as I’ll adhere to a plan. 
 

I’m feeling the same as with other drops. I laugh easily, feel more motivated & more romantic as well.  I also feel a bit scattered, unfocused, “adhd”-ish.
 

And a minor dizziness + low energy at times,  always 18-19 hours after the last dose.

 

I’m most worried re brain fog + adhd symptoms. My sister has asked if I need to be on adhd meds, so it’s apparent to outsiders.
 

 

 

 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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Augh I had a panic attack while driving today! I live in a city that is fairly new to me and I am deathly afraid of freeways and highways. I had to take a detour and it looked like I was being routed towards the freeway. I felt such a panic, pressure & pounding heart.  I had to slow down in traffic nearly stopping in order to get into the proper lane to avoid the freeway.  I was really afraid to cause an accident, and I’m lucky that the cars behind me were alert and slowed down when I slowed down.

 

This has happened in the past when I have hit this dose, 37.5 is where serotonin receptor occupancy drops a bit from 90% to 80%.  It’s quite ridiculous as 80% is still a lot of medication. 
 

I really don’t know what to do. I must drive. I live in an area that does not have other forms of transportation easily available. I can definitely avoid coffee which probably contributes to the fear. But this is a lifelong fear around freeways and highways. I have at times recently challenged it by driving to other cities. Even on 50 mg of serturline, there was still some panic but I was able to drive normally and talk myself through it. But this feels overwhelming now. 

 

 

 

 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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Hi @CeruleanSea

I’m sorry that happened to you.
Will it help once the roads become more familiar to you?

Would it help you to do practice runs of places you need to go at a time when traffic is quieter?

 

37.5mg has hit me quite hard too. I didn’t realise why though so thanks for that info. I only did a really small drop to this dose so couldn’t understand why but that explains it.

Sertraline (Lustral):  2014. Sept 50mg. Oct 100mg. Dec 150mg. 2015-2019. 150mg. 2019  Apr-May 0mg. Beg May 150mg. End May 100mg. Late June 125mg. Late Aug 100mg. 2020 Jan 75mg. April 50mg.

2022  50mg. 1Jan 45mg. 1Feb 40.5mg. Water T24Feb 39.5mg. 3Mar 38.5mg. 18Mar 38mg. 25Mar 37.5mg. 22Apr 37mg. 5May 36.5mg. 18May 36mg. 1Jun 35.3mg. 15Jun 34.5mg.  30Jun 34mg. 15Jul 33.5mg. 22Jul 33mg. 5Aug 32.5mg. 19Aug 32mg. 1Sept 31.5mg. 1Oct 31mg.  27 Oct 30.5. 16 Nov 30mg. 30 Nov 29.5mg. 14 Dec 29mg

2023. 2 Jan 28.5mg. 6 Feb 28mg. 10 Mar 27.5mg. 1 Apr 26.5mg. 1 May 26mg. 1 Jun 25.5mg. 1 Jul 25mg. 1 Aug 24.5mg. 17 Aug 24mg. 5 Sept 23.5mg. 9 Oct 23mg.

 

Desogestrel:  2014 -  present:  

Supplements Magnesium. 400mcg  Vitamin D. 10mcg.  Multivit/min. 1 tab. B Complex

 

Certirizine:   2022 May 10mg. Dec 20mg. 2023. 15mg.

 Omeprazole.:  2016 20mg. 2022  20mg.  15Jan 15mg. 9Feb 10mg. 25Feb 6.5mg. 15Mar 3mg. 3Apr 1.5mg.  15Apr 0mg   2023. 20mg. 15 Sept 15mg.

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After a thyroid checkup, it turns out that I’m very hypothyroid right now with a slow thyroid. It will take 6 weeks to be back to normal, if all goes well.

 

I feel such a relief about this diagnosis. I haven’t been feeling right and it’s good to know that there is a treatable cause.

 

With this change, I’m considering either going back to my original dose or just holding at 40.5 until I’m stabilized. 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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  • Moderator

@CeruleanSea

 

@Gridleyis on leave for a little while, so I thought I would help you out.

 

I think it would be a good idea for you to just hold at 40.5 until your thyroid is stable.

 

I too have hypothyroidism and it took about 6-8 weeks before I felt "human" again. But I had to change medications a couple of times before we found one that worked well for me.

 

Good luck and keep us posted.

PREVIOUS medications and discontinuations: Have been on medications since 1996. 

 Valium, Gabapentin, Lamictal, Prilosec and Zantac from 2000 to 2015 with a fast taper by a psychiatrist.

 Liquid Lexapro Nov, 2016 to 31-March, 2019 Lexapro free!!! (total Lexapro taper was 4 years-started with pill form)

---CURRENT MEDICATIONS:Supplements:Milk Thistle, Metamucil, Magnesium Citrate, Vitamin D3, Levothyroxine 25mcg, Vitamin C, Krill oil.

Xanax 1mg 3x day June, 2000 to 19-September, 2020 Went from .150 grams (average weight of 1 Xanax) 3x day to .003 grams 3x day. April 1, 2021 went back on 1mg a day. Started tapering May 19, 2023. July 28, 2023-approximately .87mg. Dr. fast tapered me at the end and realized he messed up. Prescribe it again and I am doing "slower than a turtle" taper.

19-September, 2020 Xanax free!!! (total Xanax taper was 15-1/2 months-1-June, 2019-19-September, 2020)

I am not a medical professional.

The suggestions I make are based on personal experience.

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@CeruleanSea

While I'm not happy for you for the thyroid diagnosis, I'm happy that it's been found and can be treated.   I hope that you'll be feeling ship-shape soon.  Take care in the meantime x

Sertraline (Lustral):  2014. Sept 50mg. Oct 100mg. Dec 150mg. 2015-2019. 150mg. 2019  Apr-May 0mg. Beg May 150mg. End May 100mg. Late June 125mg. Late Aug 100mg. 2020 Jan 75mg. April 50mg.

2022  50mg. 1Jan 45mg. 1Feb 40.5mg. Water T24Feb 39.5mg. 3Mar 38.5mg. 18Mar 38mg. 25Mar 37.5mg. 22Apr 37mg. 5May 36.5mg. 18May 36mg. 1Jun 35.3mg. 15Jun 34.5mg.  30Jun 34mg. 15Jul 33.5mg. 22Jul 33mg. 5Aug 32.5mg. 19Aug 32mg. 1Sept 31.5mg. 1Oct 31mg.  27 Oct 30.5. 16 Nov 30mg. 30 Nov 29.5mg. 14 Dec 29mg

2023. 2 Jan 28.5mg. 6 Feb 28mg. 10 Mar 27.5mg. 1 Apr 26.5mg. 1 May 26mg. 1 Jun 25.5mg. 1 Jul 25mg. 1 Aug 24.5mg. 17 Aug 24mg. 5 Sept 23.5mg. 9 Oct 23mg.

 

Desogestrel:  2014 -  present:  

Supplements Magnesium. 400mcg  Vitamin D. 10mcg.  Multivit/min. 1 tab. B Complex

 

Certirizine:   2022 May 10mg. Dec 20mg. 2023. 15mg.

 Omeprazole.:  2016 20mg. 2022  20mg.  15Jan 15mg. 9Feb 10mg. 25Feb 6.5mg. 15Mar 3mg. 3Apr 1.5mg.  15Apr 0mg   2023. 20mg. 15 Sept 15mg.

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Thanks for the support, everyone!   

 

I've figured out how to manage dosing for now.  I'm going down to 40 from 40.5.  i do feel tired and unable to bother at times.  But dissolving in 50 ml of water and removing 10ml (2 teaspoons) of water is easy.    I started this last night and feel fine.

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

Link to comment

Feeling pretty good on 40 mg of sertraline!  I do feel the drop from 40.5 mg to 40 a bit, which I did not expect. Mostly I feel more motivated, without a lot of increased anxiety.

 

Still planning to stick here until my thyroid test comes back normal.  The improved treatment is providing me with more energy already.

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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  • 2 weeks later...

Still here, just waiting for my thyroid to normalize until I continue with my drop.   

 

I do have to say, my focus is not as good as it was on a higher dose.  This is paradoxical to me, as I remember having trouble focusing on the sertraline at first.  What has changed?

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

Link to comment
  • 2 weeks later...

I'm just checking in. Things are going well. Much less brain fog due to my health improving all around.   Looking forward to summer!

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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  • 1 month later...

Hello everyone, I am back. I've been primarily on 40 mgs during this time.

 

I feel it would make most sense to drop to 37.5.   I am nervous about this.  I honestly feel the drop of receptor occupancy at this level in great measure.

 

One thing I should probably do, is taper off caffeine. Or limit to one cup a day. I drink coffee several times a day.  I rely on it a lot to break through ssri-induced apathy. 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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  • Moderator Emeritus
9 hours ago, CeruleanSea said:

I feel it would make most sense to drop to 37.5.   I am nervous about this.  I honestly feel the drop of receptor occupancy at this level in great measure.

 

If you feel nervous about making a reduction of that size then you can always make a smaller reduction.  For example reduce to 39mg.  If you are anxious about it, then that can add fear and consequently symptoms which are not related to the withdrawal but are caused by the anxiety.  See the following labelled diagram which lists symptoms of anxiety.  It would be very easy to think that you are experiencing withdrawal symptoms when they might be the worry about the reduction.

 

https://www.getselfhelp.co.uk/anxiety-self-help/

 

Image

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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Thanks for this suggestion C C! 
 

I dropped to 37.5 last night. Currently it’s 4 o clock in the morning & I barely got any sleep.  I drank a strong coffee yesterday afternoon + took a stimulant antihistamine for allergies.   The combination has been a predictably bad one. 

 

My mind raced with worry all night.  On the one hand, this is good as I’ve been dragging + unmotivated. I now feel sheer motivation. In the night, I recalled and listed out for myself tasks that had been overlooked at work.  
 

On the other hand, I really need sleep + not to panic.  
 

In the night, I ordered some caffeine pills that allow for a taper of caffeine without migraines. I’m ready to change this habit.

 

 I’m also planning to switch to a non-stimulating antihistamine.

 

Tomorrow night, planning on 39 mg.

 

 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

Link to comment

I bumped back up to 40 mgs last night & am back to myself. Planning to drop to 39 mgs after the weekend & stay there for the month. 
 

I’m spending the weekend in nature at a lake cottage in Wisconsin, it’s very fun & an amazing natural antidepressant!

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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  • Moderator Emeritus

Jumping your doses up and down is not recommended.  It takes about 4 days for a dose to get to full level in the blood and a bit longer for it to register in the brain.

 

Also the effect of changing your doses has a cumulative effect on the nervous system.  Something they you might have done a few times in the past and it worked, you might try to do it again and you get destabilised.

 

It sounds like you changed the dose of your Zoloft when that may not have been the cause of the issues that arose.

 

What we see here at SA is that some members cause their own issues by not being patient and careful.  When this happens they will have to deal with the consequences.

 

My suggestion would be to hold off on making a reduction until you get the caffeine/antihistamine sorted out.  It is recommended to only make one change at a time.

 

Keep it Simple, Slow and Stable

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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  • 3 weeks later...

I’ve been able to switch to 37.5 mgs from 40. I have been successful here for the last couple of weeks.

 

I’ve noted occasional uncharacteristic outbursts of anger. Yet I’ve also experienced a few hot flashes.   It’s possible that I’m experiencing menopausal changes (peri menopause) & symptoms, or that the sertraline was treating these symptoms at a higher dose.

 

The last week was also unusually stressful. I have a plan for better self care in the coming week.

 

 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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  • Moderator Emeritus
4 minutes ago, CeruleanSea said:

The last week was also unusually stressful.

 

Increased stress can worsen withdrawal symptoms.  Be sure to hold for the 4 weeks or longer if needed and make your next reduction 10% of less of the current dose, so 10% would be 33.75mg.

 

Please update your drug signature with the (full date and the dose)Account Settings – Create or Edit a signature

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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At this dose, I'm experiencing some intrusive thoughts. I am able to shake them off.  They are often in the realm of magical thinking and superstition,  almost too embarrassing to describe.   OCD-like, in the sense that something bad will happen or something good will happen based on minor actions. I am not 'delusional' in the sense that I am aware that these thoughts are not real.  and I am fighting them off.    I did have symptoms like these before I went on medication 20 years ago.

 

I wanted to note -- I am having some unusual physical symptoms including sudden hair thinning. My doctor is running thyroid and B12 labs to see if I may be having a health problem that is contributing to this.  If so, this could also contribute to OCD-like symptoms.

 

 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

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Hi @CeruleanSea

 

I notice in your drug signature that you're taking Vitamin D

Vitamin D can be activating to our hypersensitive systems in withdrawal. Reactions can exacerbate symptoms and contribute to higher levels of uneasiness.

Have you considered foregoing the supplement in favor of natural sunlight?

 

Are you still drinking coffee or have you successfully eliminated caffeine as planned?

Caffeine can increase withdrawal symptoms. 

 

1 hour ago, CeruleanSea said:

I am having some unusual physical symptoms including sudden hair thinning.

 

It's good that you're getting medical tests to be on the safe side. 

I can share that I did have a phase in withdrawal where I had significant hair loss. This has since resolved. 

I have seen other members report similar experiences. 

 

Best of luck to you on your continuous healing journey,

A.

 

1996-2018 - misc. polypharmacy, incl. SSRIs, SNRIs, neuroleptics, lithium, benzos, stimulants, antihistamines, etc. (approx. 30+ drugs)

2012-2018 - 10mg lexapro/escitalopram (20mg?)    Jan. 2018 - 10mg -> 5mg, then from 5mg -> 2.5mg, then 0mg  -->  July 2018 - 0mg

2017(?)-2020 - vyvanse/lisdexamfetamine 60-70mg    2020-2021 - 70mg down to 0mg  -->  July 2021 - 0mg

March-April 2021 - vortioxetine 5-10mg (approx. 7 weeks total; CT)  -->  April 28th, 2021 - 0mg

supplements: magnesium powder (dissolved in water) as needed throughout the day; 1 tsp fish oil w/ morning meal; 2mg melatonin 

August 1, 2022 - 1 mg melatonin

 

Courage is fear that has said its prayers.  - Karle Wilson Baker

love and justice are not two. without inner change, there can be no outer change; without collective change, no change matters.  - Rev. angel Kyodo williams

Holding multiple truths. Knowing that everyone has their own accurate view of the way things are.  - text on homemade banner at Afiya house

 

I am not a medical professional; this is not medical advice. 

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@Ariel thanks for mentioning this.  This reminds me —I’ve been back on pseudoephedrine this week for severe allergies. It’s time to discontinue that medication & find another solution.

 

As for Vitamin D, unfortunately I have a health condition that reduces my ability to absorb & utilize Vitamin D.  I’ll be continuing with it.

 

And caffeine — I still need to taper! I’ve got the tapering pills but haven’t wanted to start.

 

 

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

Link to comment

Wow, I'm starting to notice something positive about this current dose.   I

 

My social skills have improved!   I am more aware of other people's moods and nonverbal communication.  

 

I am experiencing a broader range of moods myself.  I am laughing more, and I think this is something people are responding positively to.   

 

Also, fingers crossed, NO PANIC ATTACKS at this dose yet -- and it has been a dose that has been tough for me to adjust to in the past.  

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

Link to comment
  • Moderator Emeritus

That's good news.  There was a lower dose when I started noticing my emotions returning.

 

Just be aware that sometimes it might be a bit overwhelming.

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

Link to comment

Thanks so much, Chessie. yes when I was unmedicated I had a feeling of often fencing with my difficult feelings.  We will see what I can do!

Zoloft 50 mg since 2019.   
2024. January. 33.75 February. 33.75 March 32.5 April 30.0

2023. January 33.75 mg  February 32.5 mg March 30.0 mg April 27.5 mg June 50 mg August 40 mg September-December 37.5 mg December 33.75 mg 

2022. January 50mg February 45 mg March 40.5 April-November 37.5  December 33.75 mg

 

Prior to discontinuation:  20 years of a variety of antidepressants & anti-anxiety meds from months to  years at a time (fluoxetine, nefazodone, venlafaxine, clonazepam, hydroxyzine).  I was unknowingly experiencing discontinuation and was frequently diagnosed with anxiety/exacerbations of previous illness as opposed to discontinuation. 

 

Supplements: Fish oil, Vitamin D3, magnesium,  B complex, l-theanine

 

Link to comment
  • Moderator Emeritus
3 hours ago, CeruleanSea said:

I had a feeling of often fencing with my difficult feelings.

 

I learned CBT not long before I found SA and it was helpful during taper and now that I'm off completely.  There are other non drug coping skills that I learned and use, including trying to work out the cause of the issue (eg hungry, tired, overwhelmed, lonely) and often use self talk and calming techniques.

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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