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kestrel28: On various SSRIs and antipsychotics for over three decades


kestrel28

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Hello, everyone, 

 

My name is kestrel28,  and I have been on a huge variety of psych meds since 1991 when I was first diagnosed with panic and OCD and anxiety.  

For many years I was taking 60 mg prozac and klonopin (to dull the edge of the prozac).  

 

After a while, the prozac did not do its job--it was the poop out effect.  So,  I had drs. prescribe other antidepressants (lexapro, paxil, zoloft).  all which did not work with me.  

 

So, I went back on prozac when those did not work, and, I noticed that the prozac did not do the same thing that it did the first time.  So, I was given some antipsychotics to take (zyprexa, seroquel, abilify, and rexulti).  Not all at once.  

 

The only one that seemed to work for me was rexulti.  The only problem I have had after being on this for about five years is the super weight gain (over 40 pounds), carb cravings.  Whenever I did taper and get off of it, I lost a lot of weight, even on the prozac.  

 

So, I am wondering if what I am experiencing here is kindling (the sensitivity) to being on and off two drugs:  prozac and rexulti.  

 

For a long time (from 2020-early 2022),  I was taking 20 mg prozac and .5 mg rexulti and 1.5 mg klonopin.   I  thought I was doing A-OK.   Only, I had so sexual feeling, was emotionally blunted, and I was feeling extremely fatigued.  

 

I told my psychiatrist that I wanted to go off the rexulti for good, because the weight gain was unbearable, and I was afraid of becoming diabetic.  

 

This was AFTER I had discontinued prozac for about a month and a half (february 2022 to late march 2022), because I wanted to have my sexual feelings back.  

 

Long story short, I am off the rexulti for good, BUT,  I am back on the prozac (been on 20 mg for 12 days),  and I am feeling nauseous, and it feels like I can feel my nerves tingling like I had just had 6 cups of coffee.  

 

I need to know if this sensitivity of my nervous system trying to re-establish a medication many times?  

 

Thanks in advance. 

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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  • ChessieCat changed the title to kestrel28: On various SSRIs and antipsychotics for over three decades
  • Administrator

 Hi, Kestrel.

 

Welcome to Surviving Antidepressants. 

 

On 4/8/2022 at 8:34 PM, kestrel28 said:

Long story short, I am off the rexulti for good, BUT,  I am back on the prozac (been on 20 mg for 12 days),  and I am feeling nauseous, and it feels like I can feel my nerves tingling like I had just had 6 cups of coffee.  

 

I need to know if this sensitivity of my nervous system trying to re-establish a medication many times?  

 

Yes, it's likely some of your symptoms are nervous system dysregulation from going on and off various drugs. But it's possible that the antipsychotic was covering up some of the agitation caused by the antidepressant, so some of your symptoms may also be a side effect of the Prozac. You may benefit from reducing the Prozac dose. Reinstatements work best at very small doses. According to your signature, you went off fluoxetine cold turkey in February and then reinstated at the full 20 mg in March. You may want to reduce the Prozac to 10 mg and see how you do. Prozac has a very long half life, so even when you go cold turkey, it stays in your system for several weeks. 

 

On 7/2/2011 at 2:11 PM, Altostrata said:

Prozac has the longest half-life of any SSRI. After you take it for a few days, half-life is about 16 days. Fluoxetine itself has a half-life of 2-4 days, but as it is processed, your body creates an active antidepressant metabolite, norfluoxetine, which has a half-life of 7-15 days. So Prozac keeps on extending its half-life as it is metabolized.

 

 

Here are some links for more information on reinstatement and tapering. 

 

About reinstating and stabilizing to reduce withdrawal symptoms

 

Tips for tapering off fluoxetine (Prozac)

 

Why taper by 10% of my dosage?

 

The Windows and Waves Pattern of Stabilization

 

Please update your signature to include your full drug history. The first post in this thread will show you what we need included:

 

How to Summarize Your Drug History in Your Signature

 

As you provide more information, we can help you set up a taper strategy. I'm concerned that you stopped an antipsychotic after being on that class of drugs for several years. So please let us know more about how you came off Rexulti. 

 

As you provide a complete drug history, we'll be able to help you set up a game plan for coming off these drugs. For now, you may want to go ahead and reduce the Prozac to 10 mg and see if that helps. 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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Well, I did decide to go off rexulti somewhat gradually.  Not from .5 mg, but then .25 mg for two weeks and then stopping it.  

 

Rexulti is the only one antipsychotic I have used in the past 5 years, and at relatively smaller doses.  

 

 

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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15 days in, on 20 mg prozac, and my nerves feel on edge, like I drank a pot of coffee.  I made sure that I didn't have any caffeine today.   

 

I called up my dr., and he wanted to take me off prozac again!  Without tapering.  I told him I would stay on until our next meeting.  He then snapped at me and said "Well why did you call me in the first place?" I said "because I am feeling very shaky".   He said "Well, please don't call me from now until the appointment".   

 

He then suggested that since I was running out of options regarding other medications,  he decided that next time we talk I would maybe try tricyclic antidepressants or MAOIs.  

 

I don't want to take any of those!  

 

One of the only reasons I am staying on the prozac is this: I heard that it is extremely beneficial if you are on a benzo, (I am on Klonopin) 1.5 mg per day, and they say to have an SSRI in your system helps if you are going to taper off of klonopin. 

 

I am so sick and tired of the shell games that drs. play with meds!  

 

 

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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  • Moderator Emeritus
18 hours ago, Shep said:

You may want to reduce the Prozac to 10 mg and see how you do.

 

 * * * * * *   PLEASE WATCH THIS VIDEO   * * * * * *

Antidepressant Withdrawal Syndrome and its Management

 

MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

Woohoo!!!  Finally off Pristiq    Post 0 updates start here

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

Please DO NOT TAG me - thank you.

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Thanks ChessieCat. 

 

I was just thinking about that today.   I think it would be to my advantage to try 20 mg every other day, since I cannot get a hold of 10 mg capsules right now.  

 

 

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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  • Moderator Emeritus

Even with a long half life drug like Prozac see:

 

NEVER SKIP DOSES TO TAPER

 

And you do not have to skip days.  Please see Post #1 of this topic about how to get non standard doses:

 

Tips for tapering off fluoxetine (Prozac)

 

If you decide to make a liquid from your capsules/tablets it is suggested to:

 

cross-over-changing-form-eg-tablet-to-liquid-of-drug-or-changing-brand-of-same-drug

 

 * * * * * *   PLEASE WATCH THIS VIDEO   * * * * * *

Antidepressant Withdrawal Syndrome and its Management

 

MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

Woohoo!!!  Finally off Pristiq    Post 0 updates start here

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

Please DO NOT TAG me - thank you.

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  • Administrator
7 hours ago, kestrel28 said:

One of the only reasons I am staying on the prozac is this: I heard that it is extremely beneficial if you are on a benzo, (I am on Klonopin) 1.5 mg per day, and they say to have an SSRI in your system helps if you are going to taper off of klonopin. 

 

I have never heard of this, nor do I put much credence in it. 

 

8 hours ago, kestrel28 said:

15 days in, on 20 mg prozac, and my nerves feel on edge, like I drank a pot of coffee.  I made sure that I didn't have any caffeine today.   

 

Too much Prozac. Any doctor can prescribe these drugs. Suggest you get a new doctor. 

 

Even 5mg or less might stop the withdrawal symptoms.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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  • Administrator
15 hours ago, kestrel28 said:

One of the only reasons I am staying on the prozac is this: I heard that it is extremely beneficial if you are on a benzo, (I am on Klonopin) 1.5 mg per day, and they say to have an SSRI in your system helps if you are going to taper off of klonopin. 

 

That's been messaged by some of the benzo forums that began before a lot was known about SSRI withdrawal. It's out of date information. As Alto wrote, we don't put much credence into that here. 

 

This thread explains more:

 


Taking multiple psych drugs? Which drug to taper first?

 

Note the concepts of "brakes and accelerators."  Benzos are brakes and Prozac is an accelerator. In order to preserve your sleep, it's best to come off the accelerator first and leave the brake for last. 

 

On 4/11/2022 at 6:09 AM, Shep said:

Please update your signature to include your full drug history. The first post in this thread will show you what we need included:

 

How to Summarize Your Drug History in Your Signature

 

Please update your signature so the mods don't have to re-read your thread to catch up. Having an up-to-date signature prevents mistakes being given as we help you set up a game plan for coming off your drugs. 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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4 hours ago, Shep said:

 

That's been messaged by some of the benzo forums that began before a lot was known about SSRI withdrawal. It's out of date information. As Alto wrote, we don't put much credence into that here. 

 

This thread explains more:

 


Taking multiple psych drugs? Which drug to taper first?

 

Note the concepts of "brakes and accelerators."  Benzos are brakes and Prozac is an accelerator. In order to preserve your sleep, it's best to come off the accelerator first and leave the brake for last. 

 

 

Please update your signature so the mods don't have to re-read your thread to catch up. Having an up-to-date signature prevents mistakes being given as we help you set up a game plan for coming off your drugs. 

Good points.  Thanks.  

 

I got to my PCP today and he prescribed me the 10 mg capsules.  

I am very interested in learning how to liquefy the prozac at home.  

I will follow those links.  

 

Again, thank you.  

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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19 hours ago, ChessieCat said:

 

Thanks, Chessie Cat.  

 

I just started on 10 mg today, and I feel much better!  

Thank you all for the guidelines, help, suggestions, etc.

Since I've only reinstated the drug two 16 days ago,  I am confused as what to do next.  

I read the 10 percent taper rule.   Should I stay on 10 mg for a while to see how I feel?  

I am a little confused on the putting prozac in liquid form.   If I want to do it myself, where would I get the syringe? 

 

I am very new to this, so I am really eager to learn, and hope I move slowly enough to have minimal withdrawal (if any).  

 

Again, thanks, and if I do decide to dilute the prozac in water, when would be a good time to start? 

 

 

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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  • Administrator
10 hours ago, kestrel28 said:

I read the 10 percent taper rule.   Should I stay on 10 mg for a while to see how I feel?  

I am a little confused on the putting prozac in liquid form.   If I want to do it myself, where would I get the syringe? 

 

Yes, I would hold for a few weeks and give yourself time to stabilize. 

 

You can order syringes online, including Amazon. Members have reported being able to obtain syringes for free from pharmacies. 

 

10 hours ago, kestrel28 said:

Again, thanks, and if I do decide to dilute the prozac in water, when would be a good time to start? 

 

I wouldn't make any changes until you're at what moderator Brassmonkey calls "withdrawal normal." Here is his description:

 

WD Normal

 

 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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  • Administrator

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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On 4/13/2022 at 3:32 PM, Altostrata said:

thanks AltoStrata.  

 

Day 3: feeling better,  but flat, and very tired.  Having to take many naps.  Day 4 without caffeine.  

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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  • Administrator

It's only been 4 days since you reinstated fluoxetine. How have the drug effects changed over these 4 days?

 

Did you quit caffeine at the same time? How many cups a day were you drinking?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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1 hour ago, Altostrata said:

It's only been 4 days since you reinstated fluoxetine. How have the drug effects changed over these 4 days?

 

Did you quit caffeine at the same time? How many cups a day were you drinking?

It's been since last Tuesday since I cut from 20 mg to 10 mg.  I feel less shaky, but I feel really tired,  devoid of energy.  

I was so amped up from the 20 mg a few days ago that I decided to temporarily stop coffee (since this past Monday).  

I was drinking two to three mugs per day (when I was also on Rexulti), and before I got back on the 20 mg (on 3/27).  

I realize now that that was really a nervous system overload with all that caffeine on board.  

 

Still dealing with the very tired feeling in the mornings to afternoons (since cutting to 10 mg).  

 

 

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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  • Administrator

If you quit caffeine, you might also get caffeine withdrawal symptoms.

 

When were you taking Result? Please update your signature.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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On 4/17/2022 at 3:54 PM, Altostrata said:

If you quit caffeine, you might also get caffeine withdrawal symptoms.

 

When were you taking Result? Please update your signature.

I did stop caffeine for six days, but started back easily this past week with 1/2 a cup, which I can tolerate. 

I was taking Rexulti for two years, but stopped due to weight gain and cravings.  

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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  • Administrator

@kestrel28How is your sleep? Has it gotten better or worse? 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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6 hours ago, Shep said:

@kestrel28How is your sleep? Has it gotten better or worse? 

I find it very hard to get to sleep.   I often wake up unrefreshed, and end up feeling very fatigued the next morning.  Unlike before (like a few months ago), where my sleep was not interrupted and I woke up feeling refreshed.  

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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  • Administrator

@kestrel28Are you still taking clonazepam at .5 mg 3 times a day? 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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17 hours ago, Shep said:

@kestrel28Are you still taking clonazepam at .5 mg 3 times a day? 

Yes.

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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Since reinstating the prozac, I have had irritable bowels and frequent diarrhea.  It usually occurs in the AM.  I take acidophilus and am on meds (mesalamine) to keep my colitis in check.  Could it be that my body is rejecting the prozac?  

 

I am having my annual colonoscopy on Tuesday.  

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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5 hours ago, kestrel28 said:

Since reinstating the prozac, I have had irritable bowels and frequent diarrhea.  It usually occurs in the AM.  I take acidophilus and am on meds (mesalamine) to keep my colitis in check.  Could it be that my body is rejecting the prozac?  

 

You were on 20 mg in March and then reduced to 10 mg about 10 days ago. Did this symptom change for better or worse when you decreased the dose? Or is it the same? 

 

GI issues are really common with these drugs. Here is more information:

 

Digestive problems: nausea, diarrhoea, bloating, GERD

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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4 hours ago, Shep said:

 

You were on 20 mg in March and then reduced to 10 mg about 10 days ago. Did this symptom change for better or worse when you decreased the dose? Or is it the same? 

 

GI issues are really common with these drugs. Here is more information:

 

Digestive problems: nausea, diarrhoea, bloating, GERD

I think it's been increasingly more problematic.  When I was off of prozac for 6 weeks, my bowels were normal.   

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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8 hours ago, kestrel28 said:

I think it's been increasingly more problematic.  When I was off of prozac for 6 weeks, my bowels were normal.   

 

How did your bowels feel when you reduced from 20 mg to 10 mg? Just trying to see if you're dealing with a side effect or a withdrawal symptom and if you may benefit from reducing more.

 

What are your other symptoms? How intense are they on a scale of 1 - 10, with 1 being mild and 10 being severe? 

 

It may come down to figuring out which is worse - the side effects or the withdrawal symptoms and going from there. It looks like symptom such as crying and panic improved with the reinstatement, so it may be a matter of managing the upticks in GI symptoms through diet and see if they settle down as your body adjusts to the changed dose.

 

Please post your thoughts. 

 

 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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12 hours ago, Shep said:

 

How did your bowels feel when you reduced from 20 mg to 10 mg? Just trying to see if you're dealing with a side effect or a withdrawal symptom and if you may benefit from reducing more.

 

What are your other symptoms? How intense are they on a scale of 1 - 10, with 1 being mild and 10 being severe? 

 

It may come down to figuring out which is worse - the side effects or the withdrawal symptoms and going from there. It looks like symptom such as crying and panic improved with the reinstatement, so it may be a matter of managing the upticks in GI symptoms through diet and see if they settle down as your body adjusts to the changed dose.

 

Please post your thoughts. 

 

 

My bowels felt only slightly better, going from 20 to 10 mg.  I'd say my biggest symptom right now is morning lethargy--feeling unrested--having absolutely no energy whatsoever.  This is the worst part of the day for me from 8 am til about noon.   If I take a 1/2 cup of coffee, then that usually gives me a little push, without it being too harsh.   

 

My fatigue/lethargy  is pretty bad  i'd say it's a 7 out of 10.  I can get up and have breakfast, but I am extremely tired.   

 

I am wondering if the reintroduction of the prozac has affected my sleep cycle (not getting to sleep at a good hour), and having to nap.  

 

Another thing is that I cannot focus as well as I was doing before--I used to be able to sit down and read a few chapters of a book just to calm my mind--now, I cannot do that.  

I'd say it's a 5 out of 10.  

 

On a positive note, my weight has gone down since stopping rexulti (I was above 220 and now I am 213). 

 

I do note that when I exercise I have to have plenty of electrolytes on hand--water alone will not work, as I sweat profusely on prozac and klonopin.  

 

 

Ulcerative Colitis since 2006 (was on fluoxetine 60 mg for 15 years when diagnosed). 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

Late March 2022: went back on Fluoxetine 20 mg because the withdrawal symptoms were too much too handle

Current drugs: .5 mg clonazepam 3x daily, and 20 mg fluoxetine since 3/27/2022

4/12/22: started on 10 mg fluoxetine.    

4/11/22; Drastically cut coffee consumption due to severe nervousness caused by reinstatement of fluoxetine.  

4/20/22 currently only drinking 1/2 cup of coffee per day; down from 2-3 mugs when I was on Rexulti.  

 

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10 hours ago, kestrel28 said:

I'd say my biggest symptom right now is morning lethargy--feeling unrested--having absolutely no energy whatsoever.  This is the worst part of the day for me from 8 am til about noon. 

 

You're also taking clonazepam 3 times a day.  Please note that drug is a central nervous system depressant and can be vey sedating, so you may be getting side effects from the benzo. Since you're dosing three times a day, you're being sedated all day. And now being on a lower dose of a stimulating drug like Prozac, you may be over-medicated with the benzo. 

 

How many hours are you sleeping at night? I'm wondering if you might benefit from moving more of the benzo from daytime use to nighttime or even tapering off a bit of the morning dose. You'll want to stay on some of the benzo throughout your Prozac taper to preserve sleep, but you may want to reduce it a bit before you start tapering Prozac.

 

Please post your thoughts. 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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Quote

 

Jan 2020-March 2022: Rexulti .5 mg, then .25 mg for last two weeks of march, then stopped.  

Feb 2022: went off fluoxetine 20 mg without tapering

Late March 2022: bawling, crying, irritability, panic, irritability 6 weeks after withdrawing

 

 

How have you determined that your symptoms are not withdrawal from Rexulti?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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