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Tips for tapering off Zyprexa (olanzapine)


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On 5/27/2018 at 12:46 PM, Evoldnahturt said:

 

I started having heart issues while still on Olanzapine.  I still do, to some extent, but I suspect that this, like most issues caused by poor lifestyle choices, is one of those things that the body can repair on it's own once you start being good to it, so I'm not too worried about it.  Time will tell!

Hi @Evoldnahturtjust wondering what your tapering method is? Do you cut and weigh your tablets? 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, final dose on 18th March 2022 (off valium!)

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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On 5/27/2018 at 12:46 PM, Evoldnahturt said:

 

I started having heart issues while still on Olanzapine.  I still do, to some extent, but I suspect that this, like most issues caused by poor lifestyle choices, is one of those things that the body can repair on it's own once you start being good to it, so I'm not too worried about it.  Time will tell!

Hi @Evoldnahturtjust wondering what your tapering method is? Do you cut and weigh your tablets? 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, final dose on 18th March 2022 (off valium!)

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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Nicjk,

 

I tapered from 30mg Olanzapine to zero by cutting tablets.  My withdrawals were the worst at 2.5mg and less. It sucks and took about 16 weeks from my last dose until the withdrawals decreased.

 

For me there was nothing that helped the withdrawals or lack of sleep. Don’t let the doctors replace one nasty Psych drug with another. Exercise (even just a walk outside) everyday. No caffeine. Willpower. It’s tough, takes a long time, but things do get better.  

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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8 hours ago, Spideygsm said:

Nicjk,

 

I tapered from 30mg Olanzapine to zero by cutting tablets.  My withdrawals were the worst at 2.5mg and less. It sucks and took about 16 weeks from my last dose until the withdrawals decreased.

 

For me there was nothing that helped the withdrawals or lack of sleep. Don’t let the doctors replace one nasty Psych drug with another. Exercise (even just a walk outside) everyday. No caffeine. Willpower. It’s tough, takes a long time, but things do get better.  

Thanks for sharing your experience Spideygsm. Congratulations for coming off this horrible drug! It looks like you made quite large cuts which is very brave. I am keen to do a really slow microtaper but I just need to find out how it would be possible to do so using regular tablets. I’m hoping that by cutting extremely slowly some of the horrible withdrawals will be mitigated. 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, final dose on 18th March 2022 (off valium!)

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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The withdrawals suck. I had to get off the drug quickly because of very negative side effects. I withdrew under my physicians directions.

 

I exercised and drank lots of water. I did try CBD but I could tell you for sure if it helped or not.

 

Good luck. You can do it. A strong mind and not giving up is the key. I never bounced back up on a dose because I knew that would be a setback. 

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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1 hour ago, Spideygsm said:

The withdrawals suck. I had to get off the drug quickly because of very negative side effects. I withdrew under my physicians directions.

 

I exercised and drank lots of water. I did try CBD but I could tell you for sure if it helped or not.

 

Good luck. You can do it. A strong mind and not giving up is the key. I never bounced back up on a dose because I knew that would be a setback. 

Thanks very much! I’m glad you’re out of the woods

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, final dose on 18th March 2022 (off valium!)

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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On 10/9/2021 at 4:40 AM, Nicjk said:

Does anyone know if it is possible to do a daily micro taper off Olanzapine with the regular tablets? I unfortunately can't tolerate either the liquid version or the orodispersible/wafers in water. I have found an expensive scale that weighs 0.0001g and it theoretically could be possible to reduce by minuscule amounts per day but I just wonder how difficult that would be. Any ideas and input is most welcome. Thanks everyone 

 

Hi, i'm doing a standart liquid suspension tapper with a generic brand of olanzapine and its working well.

 

I just measure 20ml of filtered water with a syringe and pour in a small glass container with a plastic lid, i place my pill there and wait to dissolve for about half n hour, then i stirr very well with the syringer and take the right dose in mls following the sheet calculator for my current dose, now im removing 7.4mls out of 20, and it works, i was doing very good till now, not much side effects and improvements on my mood/mind, but lately the last reduction gave me insomnia so i cut back the dose a bit and tonight i will check if i can sleep.

Being under several meds, most antipsychotics, benzos in small periods as mood regulators. (reason: the usage of cannabis induced me severe psychosis 7 times in my life)

12 year under meds, Haldol, Risperidone (2 years), Seroquel (2 years), Aripiprazole (6-7 years) as main meds.

Clonazepam, depakene ,lithium, alprazolam in short periods, at hospitalizations (6) was under several meds at time.

2019 went cold turkey on aripiprazole after years taking it, 4 months of intense suffering, recovered after month 4-5, was doing pretty well till going back on the use of cannabis and got psychotic again

november 2019 - april 2020 spent on drug clinic, got out of it under the use of Lithium (1200mg) Depakene (700mg) Clonazapam (2mg) Olanzapine (5mg)

Between May-July 2020 i tapered of completely Clonazepam and Depakene not much problem from where i was already standing

19/10 2020 started tapering lithium - 300mg morning 600mg night

26/10 2020 lithium 300mg morning 300 mg night

30/11 2020 lithium 150mg morning 300 mg night

*Planning to start liquid 10% taper with Olanzapine in 2021 few months after ending lithium tapper.

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  • 1 month later...

Hi everyone,

 

Is anyone using the orodispersible tablet to taper ? I'd like to know if making a water solution with it is possible.

I'm tapering from 5mg, and I powered through 5-2,5mg with short-lived WD symptoms (lifting in 3-4 days), but now I am stuck at 2,33 mg with severe and longer-lasting symptoms. I'm going to be way more conservative with the last reductions, but the small orodispersible tablets make it hard to make precise cuts. Is everybody using the regular tablet or is there a way to get through with the orodispersible ones ?

- Paroxetine (2016-2018) 20mg : quit CT, no immediate WD. Protracted anhedonia, depressive and anxiety episodes.

- Paroxetine (January 2020-July 2020) 20 mg, reduced to 10mg because of induced hypomania : fast taper. No immediate WD / worsening protracted anhedonia, depression and mood instability.

- Paroxetine (March-April 2021) 10mg : AD-induced hypomania again, quit CT : some immediate WD, then worsening protracted WQ : tinnitus, visual snow, depression, mood instability, DR, muscle twitchs, and a lot of other physical symptoms.

- Paroxetine WD + antibiotic (kindling effect) lead me to being hospitalised, and put on Olanzapine (15mg, fast taper to 5mg), Sertraline (50mg). Started Lamictal in September

 

- Current taper

October 16 : 3,34mg Olanzapine 25 mg Sertraline (no immediate WD expect brain zaps for 2 days) / 100 mg Lamictal

November 11 : 1,66mg Olanzapine / 25 mg Sertraline / 100mg Lamictal

November 23 : 1,25mg Olanzapine / 25mg Sertraline / 100mg Lamictal

 

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  • Moderator

Hi LHRG,

If you read through the first post in this topic you'll see more about using the orodispersible wafer/tablets in water, down towards the bottom.

I do know one member who did so, and I'll do an @stelahere in case they sign in and come on, they'll find your post.

I'll also divert back, to your Introduction topic now too.

Edited by manymoretodays

2022 May- continuing with limited activity on site, just something I need to do right now

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider. manymoretodays

 

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  • 2 months later...

So I have a question. I want to try making a liquid dose of olanzapine especially once I start getting to really small doses. Do I use crushed up 5mg olanzapine tablet, put it in 2.5ML of DMSO, let it sit for an hour and keep stirring it. Then after that, I put it in 2.5ML of Ora-Plus, then take the dose? Or alternatively, do I mix 2.5ML of DMSO and 2.5ML of PBS first and then add the crushed up powder, shake it up, let it sit for several hours, then take the dose? I don't know how reliable this method will be once I start getting to really small doses, like 0.23mg dose. Just to clarify, I do want to start off the tapering by using crushed up powder, weighing the contents on a digital milligram scale, put it in capsules, and swallow them. As I get closer to lower doses, I wanna switch to the liquid form. When I get close to the 0.56mg dose, the weight will be in 0.0001g format and my digital milligram scale does not go that far.

Edited by Intense

3/15 Started 10mg Lexapro and 10mg Olanzapine.

11/15 Switched to 20mg Prozac and 5mg Olanzapine

4/26/21 Quit Prozac and Olanzapine cold turkey.

5/4/21 Resumed 20mg Prozac and 5mg Olanzapine just to stop the withdrawals and insomnia.

8/21 Quit 20mg Prozac cold turkey

2/13/22 Begin taper of 4.5mg olanzapine taking 45ml of a 5mg tablet dissolved in 50ml water using 10% taper, failed to fall asleep. 2/14/22 Begin taper of olanzapine taking 50ml water, or 5mg, using 2.5% taper > February 21, 2022 Start 4.88mg taper no withdrawal symptoms so far

2/27/22 Switched to 10% taper. Dropped to 4.5mg. 3/27/22 > Back to 2.5% taper. 4.38mg. 4/9/22 > 4.27mg 4/16/22 >4.16mg. 4/23 > 4.05mg 4/30 Quit taper and restarted 5mg

5/21 Restart 5mg taper on 2.5% taper 5/27 Restart 5mg taper on 2.5% taper 5/31 > 4.88mg 6/7 > 4.75mg 6/14 >  4.63mg 6/21 > 4.5mg 7/13 > 4.38mg 7/20 > 4.27mg 7/27 > 4.16mg 8/3 > 4.05mg 8/24 > 3.95mg 8/31 > 3.85mg 9/8 > 3.75mg 9/15 > 3.65mg

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  • Moderator

Hi @Intense

 

In practice most people don't worry about compounding a solution.

 

Making a suspension in clean water is better than good enough.  I used to leave the tablet for 15-60 mins to dissolve in a small brown glass bottle in the fridge, maybe breaking it in half first.  After it's sat, you just need to make sure it's well shaken or agitated just before you measure out and drink it.  That way you have a good even distribution of the active ingredient.

 

You can use the same batch for up to 7 days if your fridge is good.

 

 

I am not a health professional - your actions are your own.  

Please do not seek tapering support via private message

My taper visualised as a graph   |   My intro thread

Backdrop:  2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole

2015: olanzapine  10 -> 7½ -> 6⅔ -> 5mg  by crude pill cutter

2018:  Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold

Jan 2019 2.50mg water titration -> Jan 2020 1.214  -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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I think I will use herewego's advice regarding using the Ora-Plus, water, and crushed up olanzapine powder. In my experience, I tried putting the olanzapine tablet by itself in water and it disintegrated, but it quickly sunk to the bottom. So, I tried to pipette with the syringe and I wasn't able to get a good amount of the olanzapine, and thus I wasn't able to go to sleep. And I think even if I had left the olanzapine in the fridge for 1 or 2 hours and shook it around for some moments, it probably wouldn't have done anything and the powder would still be in the bottom. I think herewego's advice sounds better. I was able to get Ora-Plus on Amazon easily, so that's not a problem.

3/15 Started 10mg Lexapro and 10mg Olanzapine.

11/15 Switched to 20mg Prozac and 5mg Olanzapine

4/26/21 Quit Prozac and Olanzapine cold turkey.

5/4/21 Resumed 20mg Prozac and 5mg Olanzapine just to stop the withdrawals and insomnia.

8/21 Quit 20mg Prozac cold turkey

2/13/22 Begin taper of 4.5mg olanzapine taking 45ml of a 5mg tablet dissolved in 50ml water using 10% taper, failed to fall asleep. 2/14/22 Begin taper of olanzapine taking 50ml water, or 5mg, using 2.5% taper > February 21, 2022 Start 4.88mg taper no withdrawal symptoms so far

2/27/22 Switched to 10% taper. Dropped to 4.5mg. 3/27/22 > Back to 2.5% taper. 4.38mg. 4/9/22 > 4.27mg 4/16/22 >4.16mg. 4/23 > 4.05mg 4/30 Quit taper and restarted 5mg

5/21 Restart 5mg taper on 2.5% taper 5/27 Restart 5mg taper on 2.5% taper 5/31 > 4.88mg 6/7 > 4.75mg 6/14 >  4.63mg 6/21 > 4.5mg 7/13 > 4.38mg 7/20 > 4.27mg 7/27 > 4.16mg 8/3 > 4.05mg 8/24 > 3.95mg 8/31 > 3.85mg 9/8 > 3.75mg 9/15 > 3.65mg

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  • Moderator
2 hours ago, Intense said:

In my experience, I tried putting the olanzapine tablet by itself in water and it disintegrated, but it quickly sunk to the bottom. So, I tried to pipette with the syringe and I wasn't able to get a good amount of the olanzapine, and thus I wasn't able to go to sleep. And I think even if I had left the olanzapine in the fridge for 1 or 2 hours and shook it around for some moments, it probably wouldn't have done anything and the powder would still be in the bottom.

 

You do need to give it a good shake.  I was in the habit of squishing it in and out of the pipette or syringe quickly before drawing out the dose, too.  (Agitating the liquid).  It's definitely a proven and reliably accurate method done that way.

 

Of course, you're in charge of your taper, and there are many ways to skin that cat.  If the other chemicals are easily available to you, why not see how you go.  (Personally I would vigorously shake those too 🙂)

 

Also noting that any residue you see is the filler and packaging from the tablet, not the actual drug - that is too fine to see.

Edited by hayduke

I am not a health professional - your actions are your own.  

Please do not seek tapering support via private message

My taper visualised as a graph   |   My intro thread

Backdrop:  2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole

2015: olanzapine  10 -> 7½ -> 6⅔ -> 5mg  by crude pill cutter

2018:  Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold

Jan 2019 2.50mg water titration -> Jan 2020 1.214  -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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Try using warm water towards the hot side and shake vigorously. 
 

You’ll feel so much better after your long journey getting off this poison. 

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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Well, I have a 5mg olanzapine tablet. I'm thinking of just putting it in water, putting it in the fridge, shake it, and dose from that. But I don't know how much water I should use. I tried 20ML but it doesn't look like a lot of water and I don't think I can get enough medication with just 20ML water.

3/15 Started 10mg Lexapro and 10mg Olanzapine.

11/15 Switched to 20mg Prozac and 5mg Olanzapine

4/26/21 Quit Prozac and Olanzapine cold turkey.

5/4/21 Resumed 20mg Prozac and 5mg Olanzapine just to stop the withdrawals and insomnia.

8/21 Quit 20mg Prozac cold turkey

2/13/22 Begin taper of 4.5mg olanzapine taking 45ml of a 5mg tablet dissolved in 50ml water using 10% taper, failed to fall asleep. 2/14/22 Begin taper of olanzapine taking 50ml water, or 5mg, using 2.5% taper > February 21, 2022 Start 4.88mg taper no withdrawal symptoms so far

2/27/22 Switched to 10% taper. Dropped to 4.5mg. 3/27/22 > Back to 2.5% taper. 4.38mg. 4/9/22 > 4.27mg 4/16/22 >4.16mg. 4/23 > 4.05mg 4/30 Quit taper and restarted 5mg

5/21 Restart 5mg taper on 2.5% taper 5/27 Restart 5mg taper on 2.5% taper 5/31 > 4.88mg 6/7 > 4.75mg 6/14 >  4.63mg 6/21 > 4.5mg 7/13 > 4.38mg 7/20 > 4.27mg 7/27 > 4.16mg 8/3 > 4.05mg 8/24 > 3.95mg 8/31 > 3.85mg 9/8 > 3.75mg 9/15 > 3.65mg

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12 minutes ago, Intense said:

Well, I have a 5mg olanzapine tablet. I'm thinking of just putting it in water, putting it in the fridge, shake it, and dose from that. But I don't know how much water I should use. I tried 20ML but it doesn't look like a lot of water and I don't think I can get enough medication with just 20ML water.

 

I did a fair bit of trial and error with that.  50ml water worked pretty well for me in that range with a 50 or 60 ml syringe. 

 

Makes the maths simple too, just move the decimal point

 

Cheers

I am not a health professional - your actions are your own.  

Please do not seek tapering support via private message

My taper visualised as a graph   |   My intro thread

Backdrop:  2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole

2015: olanzapine  10 -> 7½ -> 6⅔ -> 5mg  by crude pill cutter

2018:  Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold

Jan 2019 2.50mg water titration -> Jan 2020 1.214  -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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So, I bought some 60ml syringes and some 50ml measuring cups on Amazon. They just came in today. I measured out 50ml water with the syringe and put it in the measuring cup. The measurements seem to be accurate. I put the olanzapine pill in the water and it started breaking up. Then I swished it with a plastic coffee stirrer and it seemed to be mixing well. I put aluminum foil over it and closed it off with a hair elastic band and put it in the fridge. I guess I leave it in there for 15-60 minutes? After that, I shake it vigorously and take the dose? So, when I put it in the water, it's not so much about seeing if the particles are evenly distributed because the stuff you see in the bottom could just be the filler and packaging from the tablet, but it's more about just making sure the actual olanzapine drug itself, which you can't see very well, is evenly distributed in the water?

3/15 Started 10mg Lexapro and 10mg Olanzapine.

11/15 Switched to 20mg Prozac and 5mg Olanzapine

4/26/21 Quit Prozac and Olanzapine cold turkey.

5/4/21 Resumed 20mg Prozac and 5mg Olanzapine just to stop the withdrawals and insomnia.

8/21 Quit 20mg Prozac cold turkey

2/13/22 Begin taper of 4.5mg olanzapine taking 45ml of a 5mg tablet dissolved in 50ml water using 10% taper, failed to fall asleep. 2/14/22 Begin taper of olanzapine taking 50ml water, or 5mg, using 2.5% taper > February 21, 2022 Start 4.88mg taper no withdrawal symptoms so far

2/27/22 Switched to 10% taper. Dropped to 4.5mg. 3/27/22 > Back to 2.5% taper. 4.38mg. 4/9/22 > 4.27mg 4/16/22 >4.16mg. 4/23 > 4.05mg 4/30 Quit taper and restarted 5mg

5/21 Restart 5mg taper on 2.5% taper 5/27 Restart 5mg taper on 2.5% taper 5/31 > 4.88mg 6/7 > 4.75mg 6/14 >  4.63mg 6/21 > 4.5mg 7/13 > 4.38mg 7/20 > 4.27mg 7/27 > 4.16mg 8/3 > 4.05mg 8/24 > 3.95mg 8/31 > 3.85mg 9/8 > 3.75mg 9/15 > 3.65mg

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12 minutes ago, Intense said:

So, I bought some 60ml syringes and some 50ml measuring cups on Amazon. They just came in today. I measured out 50ml water with the syringe and put it in the measuring cup. The measurements seem to be accurate. I put the olanzapine pill in the water and it started breaking up. Then I swished it with a plastic coffee stirrer and it seemed to be mixing well. I put aluminum foil over it and closed it off with a hair elastic band and put it in the fridge. I guess I leave it in there for 15-60 minutes? After that, I shake it vigorously and take the dose? So, when I put it in the water, it's not so much about seeing if the particles are evenly distributed because the stuff you see in the bottom could just be the filler and packaging from the tablet, but it's more about just making sure the actual olanzapine drug itself, which you can't see very well, is evenly distributed in the water?

 

Sounds about right.  I used a small brown glass bottle with a lid, left over from the chemists.  This is helpful once you get more than one dose out of the suspension, which is something to look forward to.

 

I didn't worry about stirring it after I put the tablet in to disintegrate.  Some brands take longer, but yep I found 15-60 mins was a good time frame.  Then a big shake once you're ready.  I also liked agitating the liquid with the syringe before drawing it, just to keep it all nicely mixed.  Small flakes of filler and some cloudiness are usual.  

 

Discard the mix after 7 days tops.  I used to have a pretty beat up fridge which lowered that to 3-4 but the newer one did a week easily.  Beyond that though, something chemical and gross happens - a bad metallic taste develops, and you don't know what happened to your dosage.

I am not a health professional - your actions are your own.  

Please do not seek tapering support via private message

My taper visualised as a graph   |   My intro thread

Backdrop:  2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole

2015: olanzapine  10 -> 7½ -> 6⅔ -> 5mg  by crude pill cutter

2018:  Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold

Jan 2019 2.50mg water titration -> Jan 2020 1.214  -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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After I put it in the fridge for 45 minutes, I took it, tried to shake it as best I could which I couldn't because the water was close to the top and the water could've easily came out if I shook it too hard and then agitated it with the syringe. It looked like all the olanzapine was evenly dispersed. Tried taking 4.5ml water, or 4.5mg. Tried going to sleep, but I was unable to fall asleep and I didn't get any sleep. I think I will wait till I get those small brown glass jars from Amazon and try it again.

3/15 Started 10mg Lexapro and 10mg Olanzapine.

11/15 Switched to 20mg Prozac and 5mg Olanzapine

4/26/21 Quit Prozac and Olanzapine cold turkey.

5/4/21 Resumed 20mg Prozac and 5mg Olanzapine just to stop the withdrawals and insomnia.

8/21 Quit 20mg Prozac cold turkey

2/13/22 Begin taper of 4.5mg olanzapine taking 45ml of a 5mg tablet dissolved in 50ml water using 10% taper, failed to fall asleep. 2/14/22 Begin taper of olanzapine taking 50ml water, or 5mg, using 2.5% taper > February 21, 2022 Start 4.88mg taper no withdrawal symptoms so far

2/27/22 Switched to 10% taper. Dropped to 4.5mg. 3/27/22 > Back to 2.5% taper. 4.38mg. 4/9/22 > 4.27mg 4/16/22 >4.16mg. 4/23 > 4.05mg 4/30 Quit taper and restarted 5mg

5/21 Restart 5mg taper on 2.5% taper 5/27 Restart 5mg taper on 2.5% taper 5/31 > 4.88mg 6/7 > 4.75mg 6/14 >  4.63mg 6/21 > 4.5mg 7/13 > 4.38mg 7/20 > 4.27mg 7/27 > 4.16mg 8/3 > 4.05mg 8/24 > 3.95mg 8/31 > 3.85mg 9/8 > 3.75mg 9/15 > 3.65mg

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35 minutes ago, Intense said:

After I put it in the fridge for 45 minutes, I took it, tried to shake it as best I could which I couldn't because the water was close to the top and the water could've easily came out if I shook it too hard and then agitated it with the syringe. It looked like all the olanzapine was evenly dispersed. Tried taking 4.5ml water, or 4.5mg. Tried going to sleep, but I was unable to fall asleep and I didn't get any sleep. I think I will wait till I get those small brown glass jars from Amazon and try it again.

 

If that's your first cut, not surprising.

 

Best to start with the full 5mg of liquid and see how you adapt to that over a while.  Some people have trouble just crossing over to a liquid even with the same amount of the drug in it, so best to start there and see how you go.

 

Insomnia wouldn't be unusual after a cut anyway.  There are avenues for gentler tapers than 10%/mo - I based mine around the Brass Monkey Slide Taper, which uses a 2.5% cut per week for four weeks, then a two week hold as a template.  Obviously you always adjust the times and amounts as your body dictates  

I am not a health professional - your actions are your own.  

Please do not seek tapering support via private message

My taper visualised as a graph   |   My intro thread

Backdrop:  2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole

2015: olanzapine  10 -> 7½ -> 6⅔ -> 5mg  by crude pill cutter

2018:  Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold

Jan 2019 2.50mg water titration -> Jan 2020 1.214  -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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2011 protracted withdrawal symptoms from Effexor, managed to come off
2013-2015  risperidone consta 50 mg, started tapering from March 2015 to 1,66mg/day and from 02/2015 started seroxat 10mg/day

01/17 Seroxat 2,0mg,olanzapine 5mg,risperidone consta 25mg/every 15days

05/17 Seroxat 1mg,olanzapine 5mg,risp.consta 25mg/every 15days

06/17 Seroxat 2drops,olanzapine 5mg,liquid risperidone2mg

07/17 Seroxat 1 drop,olanzapine 5mg,Risperidone 0mg, 10/17 Seroxat 0mg,olanzapine,5mg,Risperidone 0mg, 12/17 Seroxat 1/2 drop, olanzapine 5mg,  04/18 Olanzapine 1,25mg, 04/18 xanax 0,5mg

24/06/2019 doc said to take 10mg olanzapine for 13days and down to 5mg
 been taking 10mg for 14 days, 5mg for 8 days  and  tapered to  3/4quart. 5mg  for 14 days, 1/2 for 14 days,

01/08/19 2,5mg

08/2021 5mg olanzapine

Supplements Omega 3, Turmeric, Bacopa monneri, Mucuna Pruriens

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So, I put the olanzapine in a brown glass jar and put it in the fridge. After shaking and agitating it with a syringe, I took 50ml of water, or 5mg, and I was able to go to sleep. I guess I might need to taper more slowly like you said.

3/15 Started 10mg Lexapro and 10mg Olanzapine.

11/15 Switched to 20mg Prozac and 5mg Olanzapine

4/26/21 Quit Prozac and Olanzapine cold turkey.

5/4/21 Resumed 20mg Prozac and 5mg Olanzapine just to stop the withdrawals and insomnia.

8/21 Quit 20mg Prozac cold turkey

2/13/22 Begin taper of 4.5mg olanzapine taking 45ml of a 5mg tablet dissolved in 50ml water using 10% taper, failed to fall asleep. 2/14/22 Begin taper of olanzapine taking 50ml water, or 5mg, using 2.5% taper > February 21, 2022 Start 4.88mg taper no withdrawal symptoms so far

2/27/22 Switched to 10% taper. Dropped to 4.5mg. 3/27/22 > Back to 2.5% taper. 4.38mg. 4/9/22 > 4.27mg 4/16/22 >4.16mg. 4/23 > 4.05mg 4/30 Quit taper and restarted 5mg

5/21 Restart 5mg taper on 2.5% taper 5/27 Restart 5mg taper on 2.5% taper 5/31 > 4.88mg 6/7 > 4.75mg 6/14 >  4.63mg 6/21 > 4.5mg 7/13 > 4.38mg 7/20 > 4.27mg 7/27 > 4.16mg 8/3 > 4.05mg 8/24 > 3.95mg 8/31 > 3.85mg 9/8 > 3.75mg 9/15 > 3.65mg

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Hi, just sharing the method I am using right now. I make a fresh water suspension everyday. I draw 10ml water with a 10ml syringe and drop it in a glass, dissolve half a 5mg orodispersible tablet (cut it in half with my finger nails because I'm tapering from 2,5mg), stir it with the syringe and draw immediately the ammount I'm taking. I make 2,5% cuts each time, I measure by the scale in the syringe, each time I cut half a ml. I make a cut every 15 days to a month or even more depending on symptoms, life, etc. It may seem innacurate but I can get an even enough dose with this method, I don't have any symptoms of withdrawal at the moment. The advantage is it's quick, easy, no calculating involved. I made a kit (syringe, old vitamina package with a lid) that I have in my purse so I can do it when going out. Just sharing my thoughts on the subject, hope this helps someone understand this method better. I am not saying it is the best method, each one of us has a preference.

2007 - 15mg olanzapine, mood stabilizer, benzo, quetiapine 2009 - aripiprazol, benzo, lamotrigine 100mg 2015 - olzp 15mg, zolpidem 2017 - trazodone 2 weeks, cold turkey, lamotrigine and zolpidem, olzp 15mg, mood stabilizer, benzo 2018 - olzp 5mg, Nov olzp 2,5mg down directly from 5mg no symptoms 2019 - olzp 2,5mg cold turkey Jan after 12 days reinstated, cutting pills Nov 14 days reinstated 2,5mg 2020 - failed liquid taper, reinstated 2,5mg, 2022 - started tapering líquid 2,5% reductions in January, now at 2,25mg holding untill October due to psychotic symptoms.

 

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The 2.5% microtapering method might be too slow I think. I think I'll stick to 10% taper. It may be possible that the reason I wasn't able to sleep was because I either didn't get it all distributed due to not being shaken vigorously or I switched to liquid 4.5mg too fast. Or maybe the cut was too much. I think I'll stick to liquid 5mg for now and then next month do 4.5mg and see how that goes.

3/15 Started 10mg Lexapro and 10mg Olanzapine.

11/15 Switched to 20mg Prozac and 5mg Olanzapine

4/26/21 Quit Prozac and Olanzapine cold turkey.

5/4/21 Resumed 20mg Prozac and 5mg Olanzapine just to stop the withdrawals and insomnia.

8/21 Quit 20mg Prozac cold turkey

2/13/22 Begin taper of 4.5mg olanzapine taking 45ml of a 5mg tablet dissolved in 50ml water using 10% taper, failed to fall asleep. 2/14/22 Begin taper of olanzapine taking 50ml water, or 5mg, using 2.5% taper > February 21, 2022 Start 4.88mg taper no withdrawal symptoms so far

2/27/22 Switched to 10% taper. Dropped to 4.5mg. 3/27/22 > Back to 2.5% taper. 4.38mg. 4/9/22 > 4.27mg 4/16/22 >4.16mg. 4/23 > 4.05mg 4/30 Quit taper and restarted 5mg

5/21 Restart 5mg taper on 2.5% taper 5/27 Restart 5mg taper on 2.5% taper 5/31 > 4.88mg 6/7 > 4.75mg 6/14 >  4.63mg 6/21 > 4.5mg 7/13 > 4.38mg 7/20 > 4.27mg 7/27 > 4.16mg 8/3 > 4.05mg 8/24 > 3.95mg 8/31 > 3.85mg 9/8 > 3.75mg 9/15 > 3.65mg

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5 hours ago, Intense said:

The 2.5% microtapering method might be too slow I think. I think I'll stick to 10% taper. It may be possible that the reason I wasn't able to sleep was because I either didn't get it all distributed due to not being shaken vigorously or I switched to liquid 4.5mg too fast. Or maybe the cut was too much. I think I'll stick to liquid 5mg for now and then next month do 4.5mg and see how that goes.

You must cut what you can handle safely, you must find your own tapering dosage. It may change over time though, and with different dosages it will be easier/harder and you have to adjust. For me at this point it's 2,5%. I tried 10% and 5% and it didn't work well for me. 

2007 - 15mg olanzapine, mood stabilizer, benzo, quetiapine 2009 - aripiprazol, benzo, lamotrigine 100mg 2015 - olzp 15mg, zolpidem 2017 - trazodone 2 weeks, cold turkey, lamotrigine and zolpidem, olzp 15mg, mood stabilizer, benzo 2018 - olzp 5mg, Nov olzp 2,5mg down directly from 5mg no symptoms 2019 - olzp 2,5mg cold turkey Jan after 12 days reinstated, cutting pills Nov 14 days reinstated 2,5mg 2020 - failed liquid taper, reinstated 2,5mg, 2022 - started tapering líquid 2,5% reductions in January, now at 2,25mg holding untill October due to psychotic symptoms.

 

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On 2/16/2022 at 2:59 AM, Rrsfc said:

Hi, just sharing the method I am using right now. I make a fresh water suspension everyday. I draw 10ml water with a 10ml syringe and drop it in a glass, dissolve half a 5mg orodispersible tablet (cut it in half with my finger nails because I'm tapering from 2,5mg), stir it with the syringe and draw immediately the ammount I'm taking. I make 2,5% cuts each time, I measure by the scale in the syringe, each time I cut half a ml. I make a cut every 15 days to a month or even more depending on symptoms, life, etc. It may seem innacurate but I can get an even enough dose with this method, I don't have any symptoms of withdrawal at the moment. The advantage is it's quick, easy, no calculating involved. I made a kit (syringe, old vitamina package with a lid) that I have in my purse so I can do it when going out. Just sharing my thoughts on the subject, hope this helps someone understand this method better. I am not saying it is the best method, each one of us has a preference.

Could I do the same thing but with regular olanzapine tablets? If so, how could I do it? Do I cut the tablet in half with a pill cutter and a half would be equal to 2.5mg? I don't have orodispersible tablets and that would require asking my doctor to change my prescription to orodispersible tablets and he's going to ask why do I want to change it? I think I'm going to do the 2.5% brassmonkey slide taper because it's gentler and would the take the least amount of time to fully taper off.

3/15 Started 10mg Lexapro and 10mg Olanzapine.

11/15 Switched to 20mg Prozac and 5mg Olanzapine

4/26/21 Quit Prozac and Olanzapine cold turkey.

5/4/21 Resumed 20mg Prozac and 5mg Olanzapine just to stop the withdrawals and insomnia.

8/21 Quit 20mg Prozac cold turkey

2/13/22 Begin taper of 4.5mg olanzapine taking 45ml of a 5mg tablet dissolved in 50ml water using 10% taper, failed to fall asleep. 2/14/22 Begin taper of olanzapine taking 50ml water, or 5mg, using 2.5% taper > February 21, 2022 Start 4.88mg taper no withdrawal symptoms so far

2/27/22 Switched to 10% taper. Dropped to 4.5mg. 3/27/22 > Back to 2.5% taper. 4.38mg. 4/9/22 > 4.27mg 4/16/22 >4.16mg. 4/23 > 4.05mg 4/30 Quit taper and restarted 5mg

5/21 Restart 5mg taper on 2.5% taper 5/27 Restart 5mg taper on 2.5% taper 5/31 > 4.88mg 6/7 > 4.75mg 6/14 >  4.63mg 6/21 > 4.5mg 7/13 > 4.38mg 7/20 > 4.27mg 7/27 > 4.16mg 8/3 > 4.05mg 8/24 > 3.95mg 8/31 > 3.85mg 9/8 > 3.75mg 9/15 > 3.65mg

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On 2/22/2022 at 5:27 PM, Intense said:

Could I do the same thing but with regular olanzapine tablets? If so, how could I do it? Do I cut the tablet in half with a pill cutter and a half would be equal to 2.5mg?

 

Much easier and more accurate to keep the whole tablet suspension in the fridge.

 

Cutting pills is crude and inaccurate, you can easily see big wobbles in your dosages doing this and no one needs that.

 

I wouldn't be shy of finding a different doctor who supports your taper either, if your present one is hostile to the notion.

I am not a health professional - your actions are your own.  

Please do not seek tapering support via private message

My taper visualised as a graph   |   My intro thread

Backdrop:  2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole

2015: olanzapine  10 -> 7½ -> 6⅔ -> 5mg  by crude pill cutter

2018:  Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold

Jan 2019 2.50mg water titration -> Jan 2020 1.214  -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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  • 2 months later...

Hi everyone, I spent a year and 3 months tapering off Valium and I want to begin my Olanzapine in a couple of months (I am on 5mg). Has anyone come across any articles and information regarding the distribution of the medication in the pills? Is the medication evenly distributed throughout the pill? I already know that I can’t tolerate the liquid version of Olanzapine unfortunately- I tried switching to liquid and had a terrible time for almost 3 weeks so had to go back to the tablet. I will either cut and weigh or have my medication compounded into capsules. Thank you 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, final dose on 18th March 2022 (off valium!)

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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1 hour ago, Nicjk said:

I will either cut and weigh

 

It might be better to crush and weigh.  Brassmonkey did his whole Paxil taper crushing and weighing tablets.  He would crush 10 tablets and have a stockpile.

 

Here are the search results for the terms "stock pile" and "stockpile" in posts by Brassmonkey:

 

stock pile&author=brassmonkey

 

stockpile&author=brassmonkey

 

1 hour ago, Nicjk said:

Has anyone come across any articles and information regarding the distribution of the medication in the pills? Is the medication evenly distributed throughout the pill?

 

See:

 

even-distribution-of-active-ingredient-in-tablet

 

Please DO NOT TAG me - thank you

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

  MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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1 hour ago, ChessieCat said:

 

It might be better to crush and weigh

I just worry that it will be very messy doing it that way - there might be excess powder left in the mortar and pestle that will be hard to scrape up. I guess I just need to look more into this method

 

In terms of the medication distribution- a while ago someone shared a really good article with me on here about this topic. I can’t seem to track it down sadly. They reassured me that the medication is evenly distributed 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, final dose on 18th March 2022 (off valium!)

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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2 hours ago, ChessieCat said:

 

It might be better to crush and weigh.  Brassmonkey did his whole Paxil taper crushing and weighing tablets.  He would crush 10 tablets and have a stockpile.

 

Here are the search results for the terms "stock pile" and "stockpile" in posts by Brassmonkey:

 

stock pile&author=brassmonkey

 

stockpile&author=brassmonkey

 

 

See:

 

even-distribution-of-active-ingredient-in-tablet

 

Thank goodness I found the post about medication distribution! It was from @brassmonkey

 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, final dose on 18th March 2022 (off valium!)

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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  • 2 months later...
On 5/26/2018 at 1:32 AM, arwilliams said:

Another reason Seroquel might be a good jump medication for last resort is that Seroquel has a 6 hour half life while Zyprexa's is more like 30.

 

This would give your brain time to reset during the day potentially.  Of course it takes longer then 6 hours for medication to clear your system.

Hi Ar, did you switch to seroquel?

Seroxat 1992 6 months

Venlafaxine 2016 - 2021 

olanzapine 2016 - 2019 

olanzapine 2020 - 2021 

olanzapine 2022 April and May on 5 mg, stopped in June at 2.5 mg

clonazepam 2022 March - present at 0.5 mg

olanzapine 2.5mg started again in July (27th) 

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1 hour ago, geezee74 said:

Hi Ar, did you switch to seroquel?

Not a great idea to switch from 1 mind altering drug to another. Quit 1 at a time. 
 

FYI, I had as much difficulty stopping Klonipine as I did Zyprexa. The Benzodiazepine withdrawal was much more intense, the Zyprexa took longer.  

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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  • 3 weeks later...

[Here] is an oral suspension guide made by Medisca, a large company specializing in compound pharmacy supplies. It states that under this preparation, the shelf-life is 14 days. I do not believe the flavored syrup is necessary, just the suspending vehicle and possibly the glycerin. Any deviation from their instructions may change the amount of olanzapine per unit volume, so please be careful with your calculations. 

 

In this particular compound, they use a vehicle called "Oral Suspend," which only pharmacies may order. This is very similar to "Ora-Plus," which has been suggested earlier on this topic. My comparison between these two vehicles was made from this [review].  

 

Also, I've found this line of [pipette syringes] for more precise administration. The increments are smaller than those regularly found on other over-the-counter syringes. They are expensive but should last with regular cleaning between uses. 

 

I have not begun tapering, so I cannot comment personally on the oral olanzapine suspension or the pipette syringes. I hope this helps!

 

[active] Zyprexa: May 14, 2022 [5 mg PRN] --> CT June 6 --> Reinstated June 18, 2022 [1.25 mg] (success) 

[active] Wellbutrin: March 2022 [300 mg XL] --> August 13 [100 mg SR] --> September 10 [50 mg SR] —> September 24, 2022 [25 mg SR] 

[active] Guanfacine: March 2022 [6 mg ER] --> August 30 [4.5 mg ER] --> September 16, 2022 [3 mg ER] 

[active] Propranolol: August 16, 2022 [5-10 mg TID PRN] (reserved for anxiety attacks, some mornings) 

[inactive] Lithium: March 2021 [1200 mg ER] --> CT August 9, 2022 (~60 mg/mL eGFR, 15 month exposure) 

[inactive] Seroquel: March 2021 [300 mg ER] --> CT January 2022 --> Reinstated February --> CT April 25, 2022 

[inactive] Lamictal: February 2022 [50 mg ER] --> CT June 13, 2022 

[inactive] Baclofen: April 2022 [30 mg] --> July 22 [20 mg] --> July 29 [10 mg] --> August 5, 2022 [10-20 mg PRN] 

[inactive] Linzess: August 30, 2022 [72 mcg PRN] // Rifaximin (SIBO): August 11, 2022 --> August 25, 2022 

[inactive] [Short Trial] Abilify: Fall 2021 [10 mg] // Jornay (methylphenidate): May 2022 [60 mg] 

[inactive] [PRN] Clonidine [0.1-0.2 mg], Doxepin [3-6 mg], Gabapentin [300-900 mg], Propranolol [10-40 mg], Trazodone [50-150 mg] 

"I indeed baptize you with water unto repentance: but he that cometh after me is mightier than I, whose shoes I am not worthy to bear: he shall baptize you with the Holy Ghost, and with fire." -- Matthew 3:11 (KJV) 

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