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keepingdixie: Venlaflaxine liquid form success stories and tips?


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Hey hi,


Just looking to hear from those who have successfully made a liquid solution of venlaflaxine and successfully tapered this way? Am half-way down having converted some of my XR to IM and cut pills but now need to make a liquid form as can't get smaller than 4.5mg odd with the cutter...



Prescribed the below after suffering from severe PTSD following an extreme reaction to just two days of Citalopram 10mg in the summer of 2015. This was prescribed for postnatal anxiety following the birth of my second child. I needed the below to get me out of hospital and back home to my kids. Ironic I know...needing drugs to help me get over drugs but hey, I've learned a lot on this journey. 


15mg mirtazapine (remeron) DONE!

50mg quetiapine (seroquel) DONE! 

225mg pregablin (lyrica) DONE!

150mg venlaflaxine (effexor) down to 75mg 

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Be interested in responses about liquid.


Your cutter - what type is it, please?


My cutter is poor.  I try to cut the tiny 12.5mg Effexor tablets in half, but may have to resort to the pain-in-the bum bead-counting.


Best wishes

Born 1945. 

1999 - First Effexor/Venlafaxine

2016 Withdrawal research. Effexor.  13Jul - 212.5mg;  6Aug - 200.0mg;  24Aug - 187.5mg;  13Sep - 175.0mg;  3Oct - 162.5mg;  26Oct - 150mg 

2017  9Jan - 150.00mg;  23Mar - 137.50mg;  24Apr - 125.00mg;  31May - 112.50mg holding;  3Sep - 100.00mg;  20Sep - 93.75mg;  20Oct - 87.5mg;  12Nov - 81.25mg;  13 Dec - 75.00mg

2018  18Jan - 69.1mg; 16Feb - 62.5mg; 16March - 57.5mg (-8%); 22Apr - 56.3mg(-2%); CRASHED - Updose 29May - 62.5mg; Updose - 1Jul - 75.0mg. Updose - 2Aug - 87.5mg. Updose - 27Aug - 100.0mg. Updose - 11Oct 112.5mg. Updose - 6Nov 125.00mg

2019 Updoses 19 Jan - 150.0mg. 1April - 162.5mg. 24 April - Feeling better - doing tasks, getting outside.  7 May - usual depression questionnaire gives "probably no depression" result.

Supps/Vits  Omega 3;  Chelated Magnesium;  Prebiotics/Probiotics, Vit D3. 

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  • Moderator Emeritus

Hi KD, welcome to SA.  I am sorry to hear that you had such a bad reaction, and even more sorry that you were given more drugs in order to leave the hospital!  You seem to have tapered very fast, not criticising but venlafaxine is notorious for having hellish withdrawal symptoms. It can seem ok, I tapered it for a whole year and felt fine. Then a month after stopping was hit by horrendous withdrawal. I reinstated 1mg and it took several months to stabilise enough to restart the taper. It took another 2 years to get off that 1mg without going into withdrawal. I am afraid that your fast taper will catch up with you. You might be best to hold the dose you are at for a while, maybe even a few months to let your brain work on adjusting. 


When you are ready there is a link here to making a liquid with tablets. 



**I am not a medical professional, if in doubt please consult a doctor with withdrawal knowledge.



Different drugs occasionally (mostly benzos) 1976 - 1981 (no problem)

1993 - 2002 in and out of hospital. every type of drug + ECT. Staring with seroxat

2002  effexor. 

Tapered  March 2012 to March 2013, ending with 5 beads.

Withdrawal April 2013 . Reinstated 5 beads reduced to 4 beads May 2013

Restarted taper  Nov 2013  

OFF EFFEXOR Feb 2015    :D 

Tapered atenolol and omeprazole Dec 2013 - May 2014


Tapering tramadol, Feb 2015 100mg , March 2015 50mg  

 July 2017 30mg.  May 15 2018 25mg

Taking fish oil, magnesium, B12, folic acid, bilberry eyebright for eye pressure. 


My story http://survivingantidepressants.org/index.php?/topic/4199-hello-mammap-checking-in/page-33


Lesson learned, slow down taper at lower doses. Taper no more than 10% of CURRENT dose if possible



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