Ccnt80 Posted December 11, 2017 Share Posted December 11, 2017 Dx: Bipolar, depression, anxiety, PTSD, treatment resistant insomnia, CFS, Fibro, chronic pain Current meds as of Dec. 2017: Lamictal 200mg bid Omeprazole 200 mg bid Motrin 800mg qam Iron 65mg qam Despiramine 125mg qhs Seroquel 300mg qhs Remeron 30 mg qhs Clonopin 0.5 mg up to 5 tabs a day as needed (can take up to 3 pills at one time) *** I very faithfully take my med as prescribed. Supplements when I remember to take them: magnesium, iodine, zinc, probiotic I attempted to drop Seroquel down to 250mg for a couple weeks and was VERY irritability and awful feeling, so I ended up moving it back to 300mg. I had also recently dropped the Clonopin down from 5 tablets to 4 tablets a day. I worry about being on Seroquel cause diabetes runs in my family. As of now, my HGa1C shows a decreased risk for diabetes. I am about 70 pounds over weight. I have lost 50 pounds since May 1. My main issue is massive insomnia. That is the main reason for the poly pharmacy. I've been dx bipolar since 2005 (I am 37), but on anti-depressants since 2002. Due to my lack of knowledge and horrid docs, was on up to 10 psych meds at a time prior to 2009. Two 3 year periods in my 20s only slept 10 hours a week, even tho I was medicated so heavily I could barely move. I was so exhausted and wrung out I wanted to die. I'm on the seroquel, remeron, and desipramine mainly for sleep but they also help mood. I average 4-6 hours sleep, but it takes me 12 hours to get it. I wake up every 45-60 minutes. So don't typically feel rested. If I nap during the day, my sleep at night is no worse. If I don't take clone pin during the day to nap, I get very irritable and overwhelmed filling. Sensory overload. I've been off work for 2.5 years this time around, for mood issues and pain issues. Link to comment
Moderator Emeritus Gridley Posted December 12, 2017 Moderator Emeritus Share Posted December 12, 2017 Welcome to Surviving Antidepressants. It's not clear from your post what it is you would like help with, except you do mention attempting to lower your dosage of Seroquel We are a site for tapering safely off psychiatric drugs. I have provided a bit of information below. We ask all of our members to fill out a signature so that all of your information can be read at a glance. This helps moderators determine you current situation and we would ask that you follow the instructions at the link below. You did include your current medications in your post. Please put this information in your signature so that it will be visible to moderators with all your posts. Please also include start dates for each medication as well as any attempted reductions in dosage. Please follow these instructions: Account Settings – Create or Edit a signature • Please leave out symptoms and diagnoses. • A list is easier to understand than one or multiple paragraphs. • Any drugs prior to 24 months ago can just be listed with start and stop years. • Please use actual dates or approximate dates (mid-June, Late October) rather than relative time frames (last week, 3 months ago) • Spell out months, e.g. "October" or "Oct."; 9/1/2016 can be interpreted as Jan. 9, 2016 or Sept. 1, 2016. At Surviving Antidepressants, it is recommended that a person taper by no more than 10% of their current dose with at least a four week hold in-between decreases. The 10% taper recommendation is a harm reduction approach to going off psychiatric drugs. Some people may have to taper at a more conservative rate as they are sensitive to even the smallest drops. To get you started, and familiarized with the protocols followed by SA, I am linking a few topics so that you have a better understanding of what is recommended here. Before you begin tapering what you need to know What is Withdrawal Syndrome?Why taper by 10% of my dosage? Tips for tapering off Seroquel (quetiapine) As you know you, are taking a number of psychiatric medications. I found no listing for one of them, Despiramine. Did you mean Desipramine? I ran all your drugs through a drug interaction checker, including Desipramine, and found a number of interactions of which you should be aware. Please let us know how we can help you. Interactions between your selected drugs Major desipramine mirtazapine Applies to: desipramine, Remeron (mirtazapine) Using desipramine together with mirtazapine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should seek immediate medical attention if you experience these symptoms while taking the medications. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Switch to professional interaction data Moderate desipramine clonazepam Applies to: desipramine, Klonopin (clonazepam) Using desipramine together with clonazePAM may add to dizziness, drowsiness, breathing problems, and other side effects. This may be more likely to occur in older adults or those with a debilitating condition. Talk with your doctor before using clonazePAM together with desipramine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Switch to professional interaction data Moderate clonazepam omeprazole Applies to: Klonopin (clonazepam), omeprazole Omeprazole may increase the blood levels and effects of clonazePAM. This can increase the risk of side effects including excessive drowsiness and breathing difficulties. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Switch to professional interaction data Moderate desipramine lamotrigine Applies to: desipramine, Lamictal (lamotrigine) Using desipramine together with lamoTRIgine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Switch to professional interaction data Moderate clonazepam lamotrigine Applies to: Klonopin (clonazepam), Lamictal (lamotrigine) Using clonazePAM together with lamoTRIgine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Switch to professional interaction data Moderate clonazepam mirtazapine Applies to: Klonopin (clonazepam), Remeron (mirtazapine) Using clonazePAM together with mirtazapine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Switch to professional interaction data Moderate desipramine quetiapine Applies to: desipramine, Seroquel (quetiapine) Using QUEtiapine together with desipramine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances (for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting). Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications, whether together or alone. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Switch to professional interaction data Moderate clonazepam quetiapine Applies to: Klonopin (clonazepam), Seroquel (quetiapine) Using clonazePAM together with QUEtiapine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Switch to professional interaction data Moderate mirtazapine quetiapine Applies to: Remeron (mirtazapine), Seroquel (quetiapine) Using QUEtiapine together with mirtazapine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances (for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting). Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with these medications, whether together or alone. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of Aug 26: 4.0mg Taper is 95% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg, iron, serrapeptase, nattokinase, L-Glutamine, milk thistle, choline I am not a medical professional and this is not medical advice. It is information based on my own experience as well as that of other members who have survived these drugs. Link to comment
Kristine Posted December 13, 2017 Share Posted December 13, 2017 Hi Ccnt80, Just thought I'd say hello and welcome you to SA. I only joined last week, so I'm a newbie! I have also had experience with both seroquel and clonazepam. Unfortunately, I dropped the seroquel and clonazepam before I found this sight and it was waaaaayyyy to quick. Your insomnia sounds horrendous 😞 just make sure you follow Gridley's advice, the moderators are here to help. Cheers. K Citalopram 20mg - 40mg ~ approx 2010 - October 2015 (stopped over one week) Parnate 20mg - 50mg and olazapine 5mg ~ Jan 2016 - May 2016 (ceased over 2 days) Lithium 450mg-900 mg and Thyroxin ~May 2016 - May 2017 Diazepam various doses (including PRN) ~ 2015 - 2017 Oxazepam various doses (including PRN) ~ May 2016 - June 2016 Lurasidone 20mg ~Mid May 2016 - Mid June 2016 Vortioxetine 10mg - 20mg ~ 6th June 2016 - 20th July 2016 (abruptly ceased) Amitriptyline 200mg ~July 2016 - September 2016 (ceased over 1 week) Nortriptyline (dose ?) ~October 2016 ~ November 2016 (abruptly ceased) Seroquel XR 100mg - 300mg ~ May 2016 - August 2017 (ceased over 3 weeks) Escitalopram 10mg - 30mg ~ August 2016 - March 2017 (ceased over 2 weeks) Bupropion 300mg ~ December 2016 - May 2017 (ceased over 1 week) Clonazepam 1.5mg daily ~ July 2016 (started tapering May 2017 - September 2017 currently on 0.375mg..ie 0.125mg TDS) 27th May 2018 5% 0.357mg (possible paradoxical reaction - see benzo thread) 28th June 5% 0.337mg, 28th July 10% 0.303mg, 12th September10% 0.272mg, 18th September reinstated 10% due to intolerable WD 0.303mg, 1st October-11th Oct 10% (1% reduction over 10 days) 0.272mg, 22nd October clonazepam ceased crossed over 10mg diazepam Dexamphatamine 20mg ~ December 2016 (started tapering October 2017 - tapered 1.25mg 4th Dec 2017, 1.25mg 19th Dec 2017 6.25mg, Speed up decrease due to major interaction between Dex and fluoxetine- ref to thread 10% 17th Feb 2018 5.63mg, 10% 21st Feb 2018 5.1mg, 10% 26th Feb 2018 4.5mg 10% 28th Feb 4.1mg, 10% 1st March 3.7mg, 10% 5th March 3.3mg, 10% 8th March 3mg, 10% 10th March 2.7mg, 10% 12th March 2.4mg, 10% 14th March 2.16mg, 10% 16th March 1.94mg, 10% 18th March 1.74mg, 10% 20th March 1.57mg, 10% 21st March 1.41mg, 10% 22nd March 1.26mg, 10% 23rd March 1.13mg, 10% 24th March 1.01mg, 10% 25th March 0.9mg, 10% 27th March 0.81mg, 10% 29th March 0.73mg, 10% 31st March 0.66mg, 10% 2nd April 0.59mg , 10% 4th April 0.53mg, 10% 6th April 0.47mg, 10% 8th April 0.42mg, 10%10th April 0.37mg, 11th April 0.2mg, 12th April 0.1mg (last dose) OFF! Fluoxetine 40mg ~December 2016 - 31 Jan 2018 reduced to 20mg (probable serotonin toxicity) 10th March 2020 10mg (1:1 ratio), 7th April 9mg, 1st May 8.5mg, 15th May 8.0mg, 27th May 7.5mg, 8th Sept 7.2mg, 2nd Oct 7mg, 19th Oct 6.8mg, 28th Oct 6.6mg, 5th Nov 6.4mg, 26th Nov 6mg, 2nd April 2021 5.9mg, 9th April 5.8mg, 19th April 5.75mg, 22nd April 5.7mg, 26th April 5.65mg,28th April 5.6mg, 1st May 5.5mg, 4th May 5.45mg, 7th May 5.4mg, 10th May 5.35mg, 12th May 5.3mg, 15th May 5.25mg, 18th May 5.2mg, 20th May 5.15mg, 22nd May 5mg, 10th July 4.5mg, 9th Aug 4.48mg (switched from syringe to pipette method), 12th Aug 4.46mg, 14th Aug 4.4mg, 18th Aug 4.38mg, 19th Aug 4.36mg, 20th Aug 4.34, 21st 4.32mg, 22nd 4.3mg, 23rd Aug 4mg (hold), (micro-taper) 12th Oct 2021 3.98mg, 14th Oct 3.96mg, 15th Oct 3.94mg, 16th Oct 3.92mg, 17th Oct 3.9mg, 18th Oct 3.88mg, 19th Oct 3.86mg, 21st Oct 3.84mg, 22nd Oct 3.82mg, 23rd Oct 3.8mg, 24th Oct 3.78mg, 25th Oct 3.76mg, 26th Oct 3.74mg, 27th Oct 3.72mg, (WD reached intolerable level, reinstated 0.06mg) 28th Oct 3.8mg, 7th March 2022 3.7mg, 21st March 3.6mg, 4th April 3.5mg, 18th April 3.4mg, 2nd May 3.3mg, 16th May 3.2mg, 20th June 3.1mg, 4th July 3mg, 18th July 2.9mg, 12th September 2.7mg, 18th October 2.5mg, 14th Nov 2.3mg, 12th December 2.1mg, 18th January 2023 1.9mg, 9th July 2023 1.88mg, 16th July 1.86mg, 23rd July 1.84mg, 30th July 1.82mg, 6th Aug 1.80mg, 10th Sept 1.7mg, 12th Oct 1.68mg, 23rd Oct 1.66mg, 30th Oct 1.64mg, 6th Nov 1.62mg, 13th Nov 1.60mg, (2:1 ratio) 30th Dec 1.597mg, 7th Jan 2024 1.595mg, 8th 1.592mg, 10th 1.589, 11th 1.587, 12th 1.585, 13th 1.583, 14th 1.58 cont… 5th Feb 1.56mg, 11th Feb 1.55mg, 19th Feb 1.54mg, 26th Feb 1.53mg, 4th March 1.52mg, 11th March 1.51mg, 25th March 1.50mg, 1st April 1.49mg, 8th April 1.48mg, 15th April 1.47mg, 22nd April 1.46mg, 29th April 1.45mg, 6th May 1.44mg, 14th June 1.43mg, 21st June 1.42mg, 12th Aug 1.41mg, 19th Aug 1.40mg, 26th Aug 1.39mg, Diazepam 10mg ~ 22nd Oct 2018, 10th November 8mg, 14th Nov 7mg, 8th December 6mg, 30th December 5mg (Nocte), 7th March 2019 4.5mg,14th March 4mg, 5th April 3.5mg, 9th April 3mg, 18th April 2.5mg,1st May 2mg, 17th May 1.75mg, 25th May 1.6mg, 4th June 1.59mg, 5th June 1.58mg, 6th June 1.57mg, 7th June 1.56mg, 8th June 1.55mg, 22nd June 1.4mg, 4th July 1.2mg, 16th July 1mg, 30th July 0.8mg, 13th Aug 0.6mg, 28th Aug 0.4mg, 10th Sept 0.2mg, 23rd Sept Off! SR Circadin 2mg (melatonin) 25th May - 20th June Zolpidem 10mg 25th May (7 tablets) Supplements: Magnesium glycinate (soluble - sip throughout the day) "Whenever you feel yourself doubting how far you can go, just remember how far you have come. Remember everything you have faced, all the battles you have won, and all the fears you have overcome" Unknown Link to comment
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