drugged Posted September 14, 2019 Author Share Posted September 14, 2019 14 hours ago, Rhiannon said: One possible consolation: I found that as I tapered down to lower doses, I got a lot of relief from the problems caused by the drugs themselves, even though I was not off them entirely. Lower doses really do make a difference. When I first started I told my doctor that my goal was to get down to the lowest possible doses of the fewest possible meds I could be stable on. I think that's still true. I've gotten back so much of myself just by getting down to lower doses. And I lost about 23 years of my life before getting there, so I can relate. If you want to come down on multiple drugs, I think one way to do it safely and simply is to pick one and taper it for a while, then put it on the back burner and hold it while you taper another one for a while. Mods, please let me know if you have found this not to be the case. It seems to me that with a large drug cocktail for a long period of time, a history like yours and at your age, this may make more sense than trying to get all the way to zero on one drug before bringing down the dosage on any other drugs. I think at our age, getting to lower and less dangerous dosages is probably a higher priority than getting all the way to zero on any one thing. Just be sure to keep your goals modest and take it slow, and take a long hold after your last cut of the first drug before you make a cut of the next drug, so that any WD symptoms will have time to catch up and resolve before you start something else. Again, mods, if you think this is dangerous, please contradict me. I feel pretty much the same way. Get off some drugs if I can and get all the other doses as low as possible. I was alternating tapering the lyrics and the venlafaxine - with both of those drugs my original dose was 300mg/day. Lyrics is now at 25mg and the ven was 75mg until a nurse practitioner upped it to 150mg back in June. My body couldn't handle that dose increase so I tried to taper back down to 75mg but I was tapering too fast. That's when I came out here on this forum. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 14, 2019 Author Share Posted September 14, 2019 September 13, 2019 4:30am get up 100 mg tramadol 75mg venlafaxine 20mg omeprazole thyroid meds Symptoms upon wakening: pain - neck, upper back, shoulders, arms, fatigued, brain fog, inability to concentrate, apathy 6:00am pain has lessened, other symptoms remain 2:00pm ate 15mg buspirone 25mg lyrica 90 beads venlafaxine Tired, brain fog, unable to concentrate or focus 7:00pm 100mg tramadol Neck and upper back pain has been increasing throughout the afternoon Feeling stressed by neighborhood noise. 8:00pm 10mg diazepam 50mg trazodone 5mg zolpidem 12:30am woke up but eventually went back to sleep 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 14, 2019 Author Share Posted September 14, 2019 Current life stresses: Medicare Advantage plan isn't going to cover any therapy sessions so I won't have that backstop this year. Other issues with our current plan mean we'll be looking at switching plans during open enrollment this fall. Current house is in an extremely noisy location. Also there's no privacy at all. Constant traffic noise and college student rentals next door. I have always had an extreme sensitivity to noise and this is really making things much more difficult for me. Lack of privacy seems to worsen my agoraphobia. We might consider moving yet again (3rd time in 12 months) if we find a more peaceful location. 20 miles from my nearest neighbor would be my personal choice but that isn't going to fly with my spouse. Closing the sale of the last house we lived in on Oct. 1st. Seriously homesick for Arizona. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Mentor ShiningLight Posted September 14, 2019 Mentor Share Posted September 14, 2019 2 hours ago, drugged said: Current house is in an extremely noisy location. Also there's no privacy at all. Constant traffic noise and college student rentals next door. I have always had an extreme sensitivity to noise and this is really making things much more difficult for me. I relate to this horrible stressor, but with immature adults next door. It's awful. I imagine you already have ear plugs and noise cancelling headphones? Now: 100 mg Zoloft am, 50 mg Trazodone. Daily drug burden decreased from 2050 in 2018 mg to 150 mg 🐢🐢 Zoloft: 1/24/23 increased to 100 mg after suicide attempt 9/17/22 cut 6 mg, 8/14/22 cut 6.5 mg, 5/7/22 cut 12.5 mg 3/20/22 cut 12.5 mg 10/26/21 cut 6 mg 10/17/21 cut 5 mg, 9/17/21 Cut 3 mg, 9/13/21 cut 4 mg, 8/29/21 Cut 2 mg 8/8/21 Cut 3 mg 7/30/21 Zoloft: Converted 25 mg to liquid. Also take 100 mg pill & 25 mg pill=150 mg total🌞 Feb 28, 2021 0 mg Gapapentin 2021 Gaba each dose 4x/day: Feb 27 7 mg (one dose only), Feb 10, 7 mg, Jan 14 10 mg 2020 Current taper schedule from Aug 30-present: drop 8 mg every 2-3 weeks. Aug 20 31 mg, Aug 18, 33 mg, July 29, 35 mg, July 23 38 mg, July 22 40 mg Jun 24 42 mg, Jun 15 44 mg, Jun 9 48 mg, May 22 50 mg, May 14 54 mg, May 7 56 mg, Apr 16 58 mg, Mar 28 60 mg, Mar 18 62 mg. Feb 26 64 mg. Feb 19, 66 mg. Jan 23, 70 mg. 2019 Dec 19, 72 mg. Nov 14 ,76 mg. Aug 8, 80 mg. Aug 6, 85 mg. Jul 26, 90 mg. Jul 11, 95 mg. Jul 16 trazodone from 100 to 50 mg. Jun 17-July 10 Slowly changed gab fr pill to liquid at same dose 100 mg 4x/d. Apr 24 Stopped klon!!! 🌞 Apr 4 Decreased gaba to 400 mg (100 mg 4x/day)-Apr 4, 2019 0.25 klon March 11 Klonopin .5 mg twice daily, varied dose til Apr 15. Started Klon fast taper 25%, short use Mar 16, 450 mg gaba 3x/day cut 600 mg--not exact!--updose after learning w/d Feb 20, 2019 1800 mg gabapentin; MD taper; off 3 days=mvt disorder & autonomic instability. July 2018 temazepam 15 mg 1-2; prn several x/wk til Jan/Feb 2019 when cold turkey, flu illness for months July 2018 started gabapentin 100 3x/day; titrated up to 1800 mg (600 3x/day) Buspar, I forget how much, 2 pills a day Jan 2017-July 2018 cold turkey. On Zoloft since maybe 2004? After trying many. *I speak from my experience. Nothing I say is medical advice. I'm not a doctor. Link to comment
drugged Posted September 14, 2019 Author Share Posted September 14, 2019 17 hours ago, Altostrata said: drugged, which drugs are you taking PRN, how often do you take each one, at what kinds of dosages? Do you often make ad hoc cocktails when you have symptom flare-ups? You're taking such a stunningly terrible combination of drugs, I'm not surprised at the symptoms you report. With your pharmacy background, why have you never called your doctors' attention to your polypharmacy and drug adverse effects? You seem to be fixed on reducing the venlafaxine first, although you are taking what I'd consider a dangerous combination of tramadol, Lyrica, diazepam, trazodone, and zolpidem. If reducing the venlafaxine is what you want to do, what kind of advice are you looking for here? We don't know of any shortcuts out of polypharmacy. See Tips for tapering off Effexor (venlafaxine) This tells you all you need to know. We recommend a taper of 10% per month, but I have a feeling you're going to want to do it your way. I often called my psychiatrist's attention to the many adverse side effects I was experiencing. His response was to add another drug or change the dose, usually increasing, of one I was already on. Every time I mentioned the cocktail to him he wasn't interested. Mind, he only allowed 10 minutes per session and always did a depression screening within that amount of time. Also, my own mind had turned to mush within the first couple years of AD use. I've found it increasingly difficult to communicate verbally. I developed anomic dysphasia and apraxia. Eventually I asked my PCP to take over prescribing all of my drugs because of my concerns about polypharmacy. He was totally supportive of my tapering off as many of the drugs as I could, at my own speed. He's the kind of doctor that will read literature you bring to him particularly if it touches on an issue he doesn't feel he has enough knowledge of. Unfortunately we moved from Arizona back to Iowa (a horrible decision that's resulted in an ongoing nightmare) and I don't have that doctor available to me any longer. You say I seem fixated on reducing the AD first. I've been alternately tapering the Lyrica and the AD over several years now. I'm working on the AD now because of the adverse reaction I had to the dose increase prescribed for me this last June. I want to get my AD dose back to where I had it for a couple of years (75mg) while I worked on the Lyrica. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 14, 2019 Author Share Posted September 14, 2019 37 minutes ago, ShiningLight said: I relate to this horrible stressor, but with immature adults next door. It's awful. I imagine you already have ear plugs and noise cancelling headphones? I have earplugs in 24/7 but haven't been able to afford noise cancelling headphones as I had to spring for a new laptop after the old one died. I'm not overly comfortable with not being able to hear natural sounds like my cat purring and talking to me or my spouse's voice. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Administrator Altostrata Posted September 14, 2019 Administrator Share Posted September 14, 2019 As you know, you have been experiencing adverse effects for years from your incompetently prescribed horrible drug cocktail. I have a feeling that no matter what you reduce, it's going to be quite a while before you feel anywhere near "normal." It may be difficult to distinguish between withdrawal symptoms from the drug you're tapering from the adverse effects of the other 9 drugs or whatever you throw in on occasion. Just the interactions and side effects of diazepam, Lyrica, zolpidem, and Tramadol are extraordinarily complex. How do you feel after a venlafaxine reduction? Why do you take it twice a day? Since you seem to have very definite ideas about how you want to proceed, not sure how much I or the staff can offer. I don't believe anything we can suggest will give you immediate relief. Please explain what you want from us. FY, ChessieCat went to the trouble of running a drug interactions report for you: On 8/17/2019 at 3:29 AM, ChessieCat said: From http://www.drugs.com/drug_interactions.html Drug Interaction Report This report displays the potential drug interactions for the following 10 drugs: Lyrica (pregabalin) buspirone venlafaxine diazepam tramadol trazodone zolpidem omeprazole levothyroxine liothyronine Major (8) Moderate (13) Minor (3) Food (8) Therapeutic Duplication (5) Interactions between your drugs Major busPIRone traMADol Applies to: buspirone, tramadol Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Do not drink alcohol or self-medicate with these medications without your doctor's approval, and do not exceed the doses or frequency and duration of use prescribed by your doctor. Also, you should avoid driving or operating hazardous machinery until you know how these medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Major busPIRone venlafaxine Applies to: buspirone, venlafaxine Using busPIRone together with venlafaxine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should seek immediate medical attention if you experience these symptoms while taking the medications. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Major busPIRone traZODone Applies to: buspirone, trazodone Using busPIRone together with traZODone can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should seek immediate medical attention if you experience these symptoms while taking the medications. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Major zolpidem traMADol Applies to: zolpidem, tramadol Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Do not drink alcohol or self-medicate with these medications without your doctor's approval, and do not exceed the doses or frequency and duration of use prescribed by your doctor. Also, you should avoid driving or operating hazardous machinery until you know how these medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Major diazePAM traMADol Applies to: diazepam, tramadol Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Do not drink alcohol or self-medicate with these medications without your doctor's approval, and do not exceed the doses or frequency and duration of use prescribed by your doctor. Also, you should avoid driving or operating hazardous machinery until you know how these medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Major traZODone traMADol Applies to: trazodone, tramadol Talk to your doctor before using traMADol together with traZODone. Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm or stiffness, tremor, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should contact your doctor immediately if you experience these symptoms while taking the medications. Using traMADol with traZODone may also increase the risk of seizures not related to the serotonin syndrome. The interaction may be more likely if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumor or head trauma. You should avoid or limit the use of alcohol while being treated with these medications. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Major venlafaxine traMADol Applies to: venlafaxine, tramadol Talk to your doctor before using traMADol together with venlafaxine. Combining these medications can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm or stiffness, tremor, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should contact your doctor immediately if you experience these symptoms while taking the medications. Using traMADol with venlafaxine may also increase the risk of seizures not related to the serotonin syndrome. The interaction may be more likely if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumor or head trauma. You should avoid or limit the use of alcohol while being treated with these medications. Avoid driving or operating hazardous machinery until you know how the medications affect you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Major traZODone venlafaxine Applies to: trazodone, venlafaxine Using traZODone together with venlafaxine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should seek immediate medical attention if you experience these symptoms while taking the medications. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate traZODone pregabalin Applies to: trazodone, Lyrica (pregabalin) Using traZODone together with pregabalin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate diazePAM omeprazole Applies to: diazepam, omeprazole Omeprazole may increase the blood levels and effects of diazePAM. This can increase the risk of side effects including excessive drowsiness and breathing difficulties. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate zolpidem venlafaxine Applies to: zolpidem, venlafaxine Using zolpidem together with venlafaxine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate zolpidem pregabalin Applies to: zolpidem, Lyrica (pregabalin) Using zolpidem together with pregabalin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate venlafaxine pregabalin Applies to: venlafaxine, Lyrica (pregabalin) Using venlafaxine together with pregabalin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate traZODone zolpidem Applies to: trazodone, zolpidem Using traZODone together with zolpidem may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate diazePAM pregabalin Applies to: diazepam, Lyrica (pregabalin) Using diazePAM together with pregabalin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate traMADol pregabalin Applies to: tramadol, Lyrica (pregabalin) Using traMADol together with pregabalin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate diazePAM traZODone Applies to: diazepam, trazodone Using diazePAM together with traZODone may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate busPIRone pregabalin Applies to: buspirone, Lyrica (pregabalin) Using busPIRone together with pregabalin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate busPIRone zolpidem Applies to: buspirone, zolpidem Using busPIRone together with zolpidem may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate diazePAM zolpidem Applies to: diazepam, zolpidem Using diazePAM together with zolpidem may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate diazePAM venlafaxine Applies to: diazepam, venlafaxine Using diazePAM together with venlafaxine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Minor traZODone liothyronine Applies to: trazodone, liothyronine Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed. Minor levothyroxine traZODone Applies to: levothyroxine, trazodone Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed. Minor omeprazole traZODone Applies to: omeprazole, trazodone Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed. Drug and food interactions Moderate diazePAM food Applies to: diazepam Grapefruit and grapefruit juice may interact with diazePAM and lead to potentially dangerous side effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Do not drink alcohol while taking diazePAM. This medication can increase the effects of alcohol. You may feel more drowsy, dizzy, or tired if you take diazePAM with alcohol. Talk to your doctor or pharmacist if you have any questions or concerns. Moderate busPIRone food Applies to: buspirone You should avoid the use of alcohol while being treated with busPIRone. Alcohol can increase the nervous system side effects of busPIRone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Patients receiving busPIRone should preferably avoid the consumption of large amounts of grapefruits and grapefruit juice. If this is not possible, the busPIRone dose should be taken at least 2 hours before or 8 hours after grapefruit or grapefruit juice. Large amounts of grapefruit and grapefruit juice may cause increased levels of busPIRone in your body. This can lead to increased adverse effects such as drowsiness. Talk to your doctor or pharmacist if you have any questions or concerns. Moderate levothyroxine food Applies to: levothyroxine The timing of meals relative to your levothyroxine dose can affect absorption of the medication. Therefore, levothyroxine should be taken on a consistent schedule with regard to time of day and relation to meals to avoid large fluctuations in blood levels, which may alter its effects. In addition, absorption of levothyroxine may be decreased by foods such as soybean flour, cotton seed meal, walnuts, dietary fiber, calcium, and calcium fortified juices. These foods should be avoided within several hours of dosing if possible. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Moderate traZODone food Applies to: trazodone Alcohol can increase the nervous system side effects of traZODone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with traZODone. Do not use more than the recommended dose of traZODone, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns. Moderate zolpidem food Applies to: zolpidem You should avoid the use of alcohol while being treated with zolpidem. Alcohol can increase the nervous system side effects of zolpidem such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. Taking zolpidem with food may delay the onset of sleep. For faster sleep onset, zolpidem should not be taken with or immediately after a meal. This will make it easier for your body to absorb the medication. Talk to your doctor or pharmacist if you have any questions or concerns. Moderate venlafaxine food Applies to: venlafaxine Alcohol can increase the nervous system side effects of venlafaxine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with venlafaxine. Do not use more than the recommended dose of venlafaxine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns. Moderate traMADol food Applies to: tramadol Alcohol can increase the nervous system side effects of traMADol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with traMADol. Do not use more than the recommended dose of traMADol, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns. Moderate pregabalin food Applies to: Lyrica (pregabalin) Alcohol can increase the nervous system side effects of pregabalin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with pregabalin. Do not use more than the recommended dose of pregabalin, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns. Switch to professional interaction data Therapeutic duplication warnings Central Nervous System (CNS) Drugs Therapeutic duplication The recommended maximum number of medicines in the 'Central Nervous System (CNS) Drugs' category to be taken concurrently is usually three. Your list includes six medicines belonging to the 'Central Nervous System (CNS) Drugs' category: Lyrica (pregabalin) buspirone venlafaxine diazepam trazodone zolpidem Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed. Duplication Psychotropic agents Therapeutic duplication The recommended maximum number of medicines in the 'psychotropic agents' category to be taken concurrently is usually three. Your list includes five medicines belonging to the 'psychotropic agents' category: buspirone venlafaxine diazepam trazodone zolpidem Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed. Duplication Antidepressants Therapeutic duplication The recommended maximum number of medicines in the 'antidepressants' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'antidepressants' category: venlafaxine trazodone Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed. Tranquilizers Therapeutic duplication The recommended maximum number of medicines in the 'tranquilizers' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'tranquilizers' category: buspirone diazepam Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed. Duplication Thyroid hormones Therapeutic duplication The recommended maximum number of medicines in the 'thyroid hormones' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'thyroid hormones' category: levothyroxine liothyronine Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed. PS My guess is you could quickly go off buspirone over 2-3 weeks and hardly notice. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
drugged Posted September 15, 2019 Author Share Posted September 15, 2019 I have a feeling that no matter what you reduce, it's going to be quite a while before you feel anywhere near "normal." It may be difficult to distinguish between withdrawal symptoms from the drug you're tapering from the adverse effects of the other 9 drugs or whatever you throw in on occasion. Just the interactions and side effects of diazepam, Lyrica, zolpidem, and Tramadol are extraordinarily complex. How do you feel after a venlafaxine reduction? Why do you take it twice a day? Since you seem to have very definite ideas about how you want to proceed, not sure how much I or the staff can offer. I don't believe anything we can suggest will give you immediate relief. Please explain what you want from us. I have been concentrating on getting the venlafaxine dose back to 75mg because the dose increase the nurse practitioner prescribed really destabilized me. I became quite ill with constant nausea, headaches, anxiety, insomnia, anhedonia, etc. At 75mg of ven along with the rest of the cocktail my body felt more stable and I had some good days. I've been hoping, probably foolishly, that I could at least get back to that relative stability. That plus getting back to where I was in May seems like a manageable goal at a time when my life doesn't seem very manageable. I don't remember how the venlafaxine dose came to be divided. I have noticed that taking the second dose earlier in the day reduces my early morning anxiety. Since I've been reducing the venlafaxine by bead counting I have only once noticed any of the symptoms I relate to ven withdrawal which is primarily increased anxiety. When that happened I held the dose steady for a few days until the anxiety diminished. Apparently, so far, my cuts have been small enough that I haven't noticed any major changes. I haven't any set ideas how to proceed once I reach my minor goal of getting to 75mg of venlafaxine. I've considered cutting the zolpidem or I could do as you suggested and cut the buspirone. I could finish tapering the Lyrica. I'm not expecting immediate relief but I admit it would be nice to feel any tiny improvement in my motivation or my ability to concentrate. What do I want from the forum? Emotional support number one. I don't have anyone in my life who I feel has my back so to speak. No one I can turn to and say, "I did X and now I'm feeling Y and Z. Anybody have an idea what's going on here?" If I go to my doctor with any symptoms he'll want me to up my AD dose or change to another AD or add a completely new drug. I want to be part of a community of people who can relate to what I'm going through. A community of people who will maybe give me encouragement and an occasional pat on the back. I have already accomplished a fair amount of tapering of the Lyrica going from 300mg/day down to 25mg/day. I've also managed to taper the venlafaxine from 300mg/day down to 75mg/day until this recent updose. I didn't have any source of advice at all when I was doing that. I just made small cuts and paid close attention to what my body was telling me. I don't want to continue to be alone with my tapering. I want someplace to go for information that I feel I can trust and that sure as h*ll isn't the medical community. If you think I'd be better off reducing/coming off one of the other drugs before continuing to taper the venlafaxine then that's what I'd probably do. I've just been trying to start with the more 'activating' drugs, leaving the 'inactivating' drugs for last. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Moderator Emeritus ChessieCat Posted September 15, 2019 Moderator Emeritus Share Posted September 15, 2019 14 hours ago, Altostrata said: PS My guess is you could quickly go off buspirone over 2-3 weeks and hardly notice. You might have missed this. It below the drug interaction quote. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
drugged Posted September 15, 2019 Author Share Posted September 15, 2019 2 hours ago, ChessieCat said: You might have missed this. It below the drug interaction quote. No, I saw it. I think I said I could certainly try the buspirone. I said that, if the moderators thought I'd be better off by concentrating on one of the other drugs I'd do it. If I do taper the buspirone do I continue the taper of the AD at the same time? 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 15, 2019 Author Share Posted September 15, 2019 August 14, 2019 2:00am wake up pain - neck, upper back, shoulders, arms, wrists, hands headache, fatigue, apathy 100mg tramadol 75mg velafaxine 20mg omeprazole 4:00am note that muscle pain has lessened but still have headache 2:00pm ate 90 beads venlafaxine 25mg lyrica 15mg buspirone headache, fatigue, apathy, irritability 6:00pm sleepy tired, upper body muscles ache 7:30pm 100mg tramadol 10mg diazepam 50mg trazodone 5mg zolpidem 11:30 woke up but went back to sleep 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Mentor Happy2Heal Posted September 15, 2019 Mentor Share Posted September 15, 2019 hi drugged, I am so sorry you are going thru this. you've come to the right place, you'll get the best advice available for tapering off these drugs. I'm about your age too and have a long drug history as well, over 40yrs but thankfully was never on as many drugs at once as you are. It's a long slow process but from where I am now, off all drugs, and 60+lbs lighter and having reversed multiple health issues (including IBS, NAFLD, allergies of all kinds, severe joint pain, GERD, high blood pressure, and more that I can't recall now) anyway, the process was well worth it! I had no idea how much the psych drugs were affecting my physical health, I also didn't realize how much my poor diet was affecting both my emotional and physical health. I don't take any drugs now for ANY thing (except the rare occasional aspirin for a headache) I bet you'll be surprised at how much better you feel as you reduce your drug load. You will probably also find that you are much stronger than you ever imagined and that you can take control of your health and therefore your life, in ways you never thought possible. I no longer let ANYONE tell me what to put into my body- that is totally and 100% up to me. It was scary at first but it's liberating to know that all of this is within my control. and when it's left up to me, guess what? I tend to make the right decisions. I no longer look to pills for quick fixes, I've learned that there are so many other ways to deal with things that have zero side effects and work better, too. anyway just wanted to drop by and offer you some support on your journey. PLEASE DO NOT SEND ME PRIVATE MESSAGES, thank you. pysch med history: 1974 @ age 18 to Oct 2017 (approx 43 yrs total) Drug list: stelazine, haldol, elavil, lithium, zoloft, celexa, lexapro(doses as high as 40mgs), klonopin, ambien, seroquel(high doses), depakote, zyprexa, lamictal- plus brief trials of dozens of other psych meds over the years started lexapro 2002, dose varied from 20mgs to 40mgs. First attempt to get off it was 2007- WD symptoms were mistaken for "relapse". 2013 too fast taper down to 5mg but WD forced me back to 20mgs June of 2105, tapered again too rapidly to 2.5mgs by Dec 2015. Found SA, held at 2.5 mgs til May 2016 when I foolishly "jumped off". felt ok until Sept, then acute WD hit!! reinstated at 0.3mgs in Oct. 2106 Tapered off to zero by Oct. 2017 Doing very well. Nov. 2018 feel 95% healed, age 63 Jan. 2020 feel 100% healed, peaceful and content PRESENT DAYS: Loving life! ❤️ with all it's ups and downs Link to comment
drugged Posted September 15, 2019 Author Share Posted September 15, 2019 (edited) I recognize some of those drugs from when I was hospitalized as a teenager. Stelazine, haldol, elavil, lithium ... I was put on a bunch of different TCAs, too. Every single one of them made me sick. Thanks for the support. Edited September 15, 2019 by ChessieCat removed quote 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Administrator Altostrata Posted September 15, 2019 Administrator Share Posted September 15, 2019 Good to hear the venlafaxine tapering is going well. How often are you reducing it, by how many beads? You are taking about 165mg right now, correct? 9 hours ago, drugged said: If you think I'd be better off reducing/coming off one of the other drugs before continuing to taper the venlafaxine then that's what I'd probably do. I've just been trying to start with the more 'activating' drugs, leaving the 'inactivating' drugs for last. Your drug burden is so excessive, my guess is that any way you can simplify it as soon as possible will help. Every single drug you take, including an occasional aspirin, contributes. Your combination of "brakes" is highly risky, but you may be a fast metabolizer and be able to handle ridiculous polypharmacy until your liver or kidneys give out. I don't know if expedited removal of the buspirone over 2-3 weeks from your collection of "brakes" will cause destabilization or not -- but look at the drug interactions report. This is like pick-up sticks or Jenga, you don't know what you can remove without a problem. You've got such high duplication of "brakes," my guess is you can do without this particular dumb drug. Honestly, you've gotten yourself in such a pickle, I don't think there's any easy way out. I don't understand how, knowing you're at risk for drug-drug interactions, you continued to augment your drug cocktail to this extent. But I seem to be a lot more worried than you about it. It's up to you to decide how long you want carry an excessive drug burden. Your guess is as good as mine. You'd change only one drug at a time, and keep notes while doing so. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
drugged Posted September 16, 2019 Author Share Posted September 16, 2019 17 hours ago, Altostrata said: Good to hear the venlafaxine tapering is going well. How often are you reducing it, by how many beads? You are taking about 165mg right now, correct? Your drug burden is so excessive, my guess is that any way you can simplify it as soon as possible will help. Every single drug you take, including an occasional aspirin, contributes. Your combination of "brakes" is highly risky, but you may be a fast metabolizer and be able to handle ridiculous polypharmacy until your liver or kidneys give out. I don't know if expedited removal of the buspirone over 2-3 weeks from your collection of "brakes" will cause destabilization or not -- but look at the drug interactions report. This is like pick-up sticks or Jenga, you don't know what you can remove without a problem. You've got such high duplication of "brakes," my guess is you can do without this particular dumb drug. Honestly, you've gotten yourself in such a pickle, I don't think there's any easy way out. I don't understand how, knowing you're at risk for drug-drug interactions, you continued to augment your drug cocktail to this extent. But I seem to be a lot more worried than you about it. It's up to you to decide how long you want carry an excessive drug burden. Your guess is as good as mine. You'd change only one drug at a time, and keep notes while doing so. I am in the fifth generation of a family of alcoholics and heavy smokers. No one on that side of my family ever died of either liver or kidney failure so maybe I have genetically superior liver and kidney function. I've never smoked, I've never used any illicit drug, and I don't drink. I'm not looking for an easy way out and I AM obviously concerned or I wouldn't be here trying to explain myself again. How did "I" do this to myself? The very first thing that happened to me when I started the venlafaxine was cognitive impairment. I became hypomanic, I was suffering from delusional thinking. Then my mother died suddenly and unexpectedly. She died on 9/11/2001. In AZ, not in New York but I was in Iowa and her closest kin and the funeral home wouldn't do anything with her body until I showed up, in person, to sign the paperwork. There were no flights for what, two weeks after 9/11? I wasn't fit to drive by myself so my husband took time off work and we drove straight through. A couple of months later my husband was retired and we were living in Arizona by Thanksgiving of 2001. In going through my mother's papers I discovered that I had a half-sister. That was just part of the situation I found myself in when I was referred to this great psychiatrist and he started adding drugs. I had stopped sleeping, stopped eating, I was exercising a lot. My doctor told me that if I didn't start being able to sleep he'd have to hospitalize me. My husband wanted a divorce. I just simply gave up. So, yeah, it's all my fault that I'm in this pickle. I shouldn't have succumbed to the effects of the initial antidepressant, shouldn't have become delusional, shouldn't have cared what happened to my mother's remains (she was dead, what did she care), I shouldn't have let myself ... fill in the blank. But you know what? I did. I did all those things. I accepted all those prescriptions with only minimum protest and so here I am, a day late and many thousands of dollars short. This is where I am RIGHT NOW - fighting to get off these drugs and hoping there's something left of the intelligent, active woman I used to be underneath it all. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 16, 2019 Author Share Posted September 16, 2019 September 15, 2019 1:30am woke up 1:45am got up Pain - neck, upper back, shoulders, arms, hands Blepharitis flaring up - eyelids stuck together, pain, blurry vision 2:30am 100mg tramadol 75mg venlafaxine 20mg omeprazole 6:00am ate Pain not as bad, vision still blurred, eyes painful and itchy 2:00pm ate 90beads venlafaxine (~30mg?) 10mg buspirone (down from 15mg) 25mg lyrica 3:30pm pain in mid to lower back 6:00pm Pain returning in upper back, neck, and arms 8:00pm 100mg tramadol 10mg diazepam 50mg trazodone 5mg zolpidem Woke up several times during the night. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Mentor ShiningLight Posted September 16, 2019 Mentor Share Posted September 16, 2019 Hey drugged. It's not your fault. Hang in there. ❤ Now: 100 mg Zoloft am, 50 mg Trazodone. Daily drug burden decreased from 2050 in 2018 mg to 150 mg 🐢🐢 Zoloft: 1/24/23 increased to 100 mg after suicide attempt 9/17/22 cut 6 mg, 8/14/22 cut 6.5 mg, 5/7/22 cut 12.5 mg 3/20/22 cut 12.5 mg 10/26/21 cut 6 mg 10/17/21 cut 5 mg, 9/17/21 Cut 3 mg, 9/13/21 cut 4 mg, 8/29/21 Cut 2 mg 8/8/21 Cut 3 mg 7/30/21 Zoloft: Converted 25 mg to liquid. Also take 100 mg pill & 25 mg pill=150 mg total🌞 Feb 28, 2021 0 mg Gapapentin 2021 Gaba each dose 4x/day: Feb 27 7 mg (one dose only), Feb 10, 7 mg, Jan 14 10 mg 2020 Current taper schedule from Aug 30-present: drop 8 mg every 2-3 weeks. Aug 20 31 mg, Aug 18, 33 mg, July 29, 35 mg, July 23 38 mg, July 22 40 mg Jun 24 42 mg, Jun 15 44 mg, Jun 9 48 mg, May 22 50 mg, May 14 54 mg, May 7 56 mg, Apr 16 58 mg, Mar 28 60 mg, Mar 18 62 mg. Feb 26 64 mg. Feb 19, 66 mg. Jan 23, 70 mg. 2019 Dec 19, 72 mg. Nov 14 ,76 mg. Aug 8, 80 mg. Aug 6, 85 mg. Jul 26, 90 mg. Jul 11, 95 mg. Jul 16 trazodone from 100 to 50 mg. Jun 17-July 10 Slowly changed gab fr pill to liquid at same dose 100 mg 4x/d. Apr 24 Stopped klon!!! 🌞 Apr 4 Decreased gaba to 400 mg (100 mg 4x/day)-Apr 4, 2019 0.25 klon March 11 Klonopin .5 mg twice daily, varied dose til Apr 15. Started Klon fast taper 25%, short use Mar 16, 450 mg gaba 3x/day cut 600 mg--not exact!--updose after learning w/d Feb 20, 2019 1800 mg gabapentin; MD taper; off 3 days=mvt disorder & autonomic instability. July 2018 temazepam 15 mg 1-2; prn several x/wk til Jan/Feb 2019 when cold turkey, flu illness for months July 2018 started gabapentin 100 3x/day; titrated up to 1800 mg (600 3x/day) Buspar, I forget how much, 2 pills a day Jan 2017-July 2018 cold turkey. On Zoloft since maybe 2004? After trying many. *I speak from my experience. Nothing I say is medical advice. I'm not a doctor. Link to comment
drugged Posted September 17, 2019 Author Share Posted September 17, 2019 13 hours ago, ShiningLight said: Hey drugged. It's not your fault. Hang in there. ❤ I know I got myself into this mess. I ask myself everyday why did I trust the doctors. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Moderator Emeritus Shep Posted September 17, 2019 Moderator Emeritus Share Posted September 17, 2019 50 minutes ago, drugged said: I know I got myself into this mess. I ask myself everyday why did I trust the doctors. We're conditioned to trust doctors from cradle to grave. Plus, the mental health system has virtually no other options for most people. But once you realize the mental health system is geared toward social control and not healing, it's much easier to understand the need to taper off the drugs in order to avoid it. There are over 100 million people globally on these drugs and only a very small subset ever make the connection, as Dr. Breggin puts it, that "your drug may be your problem." You've made the connection now. You're in that small subset of those in the know. Best to not dwell on the past but simply channel your thoughts to a life free without drugs. Link to comment
drugged Posted September 17, 2019 Author Share Posted September 17, 2019 September 16, 2019 3:00am woke up Pain: neck, upper back, shoulders, arms, wrists, hands Malaise, brain fog, apathy 100mg tramadol 75mg venlafaxine 20mg omeprazole 6:00am ate Pain slightly less, malaise and apathy the same 2:00pm ate 90 beads venlafaxine 25mg lyrica 10mg buspirone 3:30pm GI cramping, stomach pain, eyes hurt and burn, tired 8:00pm 100mg tramadol 50mg trazodone 10mg diazepam 5mg zolpidem 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Mentor Happy2Heal Posted September 17, 2019 Mentor Share Posted September 17, 2019 it will get better I know first hand that beating yourself up is totally counter productive. we all do the best we can with the information we have *at the time*. you've overcome great adversity in your life, draw on your obvious strengths, they'll help you get thru this and so will the members here sending you a virtual hug💕 PLEASE DO NOT SEND ME PRIVATE MESSAGES, thank you. pysch med history: 1974 @ age 18 to Oct 2017 (approx 43 yrs total) Drug list: stelazine, haldol, elavil, lithium, zoloft, celexa, lexapro(doses as high as 40mgs), klonopin, ambien, seroquel(high doses), depakote, zyprexa, lamictal- plus brief trials of dozens of other psych meds over the years started lexapro 2002, dose varied from 20mgs to 40mgs. First attempt to get off it was 2007- WD symptoms were mistaken for "relapse". 2013 too fast taper down to 5mg but WD forced me back to 20mgs June of 2105, tapered again too rapidly to 2.5mgs by Dec 2015. Found SA, held at 2.5 mgs til May 2016 when I foolishly "jumped off". felt ok until Sept, then acute WD hit!! reinstated at 0.3mgs in Oct. 2106 Tapered off to zero by Oct. 2017 Doing very well. Nov. 2018 feel 95% healed, age 63 Jan. 2020 feel 100% healed, peaceful and content PRESENT DAYS: Loving life! ❤️ with all it's ups and downs Link to comment
Moderator Emeritus Rhiannon Posted September 17, 2019 Moderator Emeritus Share Posted September 17, 2019 Just stopped by to say hi and give you a virtual hug, if you're a hugger, or a handshake if that's more your style. (I'm a hugger. Bet that's a surprise LOL.) DO NOT BEAT YOURSELF UP. We were all told that these drugs were good. There's a whole system set up to teach us, starting in childhood, that anything a doctor gives us (including psychiatrists) is good for us and that they know everything and are smarter than we are. Then once you start taking the meds your judgment is affected and in my case (and lots of other people I have known and strangers I see on the Internet) I believed that the drugs were the only thing keeping me alive and that I needed them. I was actually quite defensive about it. It took me a long time to figure out that the drugs really were causing the problems I thought they were curing. Have you seen the book Medication Madness by Peter Breggin? It's been a great help to me, because I did a lot of crazy, self-destructive things during my years on the drugs. I am still learning to trust myself and my own judgment. I doubt I will ever be able to trust myself fully, but I'm starting to more. When we're polydrugged, it's a very long and winding path to reduce that drug burden and get off some of the meds. Not everyone can stick with it. But I get the impression that you have the intelligence and determination to do it. You're already doing it with the venlafaxine, and getting down to 25 on the Lyrica is also great. As far as Alto's suggestion about the Buspar-- her bedside manner may not always be the most delicate, but she's very knowledgeable about these drugs and she cares deeply about the suffering they cause. My impression is that she believes buspirone isn't really doing you any good, that whatever effect it's having is covered or masked by multiple other drugs you're on, so it might be a good place to get a chunk of the drugs out. My own thoughts? I don't know. I took Buspar for a while and discontinued it abruptly but that was back when I was taking so many drugs and switching them around so much, and completely unaware of the dangers of what I was doing, and pretty much cognitively dysfunctional, that I have absolutely no idea what kind of WD effect I got from that. I can't offer a ton of knowledge about different drugs and WD. There is probably a thread or section somewhere on this forum dedicated to buspirone. Maybe check it out...? What I can offer, and do want to offer, is this: I have spent a lot of time on this forum in the past, and seen and heard a lot of stories. The polypharmacy ones are always the hardest. I've seen a lot of them come and go. From following your thread so far, I think, like I said, that you have what it takes to make this work. I wish I could say "it's going to be a magical journey and it will be so wonderful and you'll get your old self back." Maybe that's true. I don't know. It's not exactly how I'd describe it for myself. It's been vastly worthwhile, but life is still life with all its ups and downs, and I'm still dealing with aging regardless. What I do know is that if I had it to do over again (that is, starting with when I realized that the drugs were causing my problems)-- the only thing I would do differently is take the first part slower and respect the drugs more and keep things very consistent and stable. I suffered a lot more in the first couple of years of tapering than I probably really needed to. But I would definitely still go down this path. And there is nowhere to start but right where you're standing. Hang in there. Keep going. Started on Prozac and Xanax in 1992 for PTSD after an assault. One drug led to more, the usual story. Got sicker and sicker, but believed I needed the drugs for my "underlying disease". Long story...lost everything. Life savings, home, physical and mental health, relationships, friendships, ability to work, everything. Amitryptiline, Prozac, bupropion, buspirone, flurazepam, diazepam, alprazolam, Paxil, citalopram, lamotrigine, gabapentin...probably more I've forgotten. Started multidrug taper in Feb 2010. Doing a very slow microtaper, down to low doses now and feeling SO much better, getting my old personality and my brain back! Able to work full time, have a full social life, and cope with stress better than ever. Not perfect, but much better. After 23 lost years. Big Pharma has a lot to answer for. And "medicine for profit" is just not a great idea. Feb 15 2010: 300 mg Neurontin 200 Lamictal 10 Celexa 0.65 Xanax and 5 mg Ambien Feb 10 2014: 62 Lamictal 1.1 Celexa 0.135 Xanax 1.8 Valium Feb 10 2015: 50 Lamictal 0.875 Celexa 0.11 Xanax 1.5 Valium Feb 15 2016: 47.5 Lamictal 0.75 Celexa 0.0875 Xanax 1.42 Valium 2/12/20 12 0.045 0.007 1 May 2021 7 0.01 0.0037 1 Feb 2022 6 0!!! 0.00167 0.98 2.5 mg Ambien Oct 2022 4.5 mg Lamictal (off Celexa, off Xanax) 0.95 Valium Ambien, 1/4 to 1/2 of a 5 mg tablet I'm not a doctor. Any advice I give is just my civilian opinion. Link to comment
Moderator Emeritus Rhiannon Posted September 17, 2019 Moderator Emeritus Share Posted September 17, 2019 Reading your daily diary thingy I see you did cut the buspirone from 15 down to 10. Keep us posted on how that goes. I'd be inclined not to make any more cuts in the venlafaxine for a while. Keep everything steady. Started on Prozac and Xanax in 1992 for PTSD after an assault. One drug led to more, the usual story. Got sicker and sicker, but believed I needed the drugs for my "underlying disease". Long story...lost everything. Life savings, home, physical and mental health, relationships, friendships, ability to work, everything. Amitryptiline, Prozac, bupropion, buspirone, flurazepam, diazepam, alprazolam, Paxil, citalopram, lamotrigine, gabapentin...probably more I've forgotten. Started multidrug taper in Feb 2010. Doing a very slow microtaper, down to low doses now and feeling SO much better, getting my old personality and my brain back! Able to work full time, have a full social life, and cope with stress better than ever. Not perfect, but much better. After 23 lost years. Big Pharma has a lot to answer for. And "medicine for profit" is just not a great idea. Feb 15 2010: 300 mg Neurontin 200 Lamictal 10 Celexa 0.65 Xanax and 5 mg Ambien Feb 10 2014: 62 Lamictal 1.1 Celexa 0.135 Xanax 1.8 Valium Feb 10 2015: 50 Lamictal 0.875 Celexa 0.11 Xanax 1.5 Valium Feb 15 2016: 47.5 Lamictal 0.75 Celexa 0.0875 Xanax 1.42 Valium 2/12/20 12 0.045 0.007 1 May 2021 7 0.01 0.0037 1 Feb 2022 6 0!!! 0.00167 0.98 2.5 mg Ambien Oct 2022 4.5 mg Lamictal (off Celexa, off Xanax) 0.95 Valium Ambien, 1/4 to 1/2 of a 5 mg tablet I'm not a doctor. Any advice I give is just my civilian opinion. Link to comment
Mentor ShiningLight Posted September 18, 2019 Mentor Share Posted September 18, 2019 14 hours ago, drugged said: I know I got myself into this mess. I ask myself everyday why did I trust the doctors. How 'bout keepin' it factual and value-neutral--at least towards yourself ? In that sense, we can say that we took medication and had adverse experiences. That's it. Now: 100 mg Zoloft am, 50 mg Trazodone. Daily drug burden decreased from 2050 in 2018 mg to 150 mg 🐢🐢 Zoloft: 1/24/23 increased to 100 mg after suicide attempt 9/17/22 cut 6 mg, 8/14/22 cut 6.5 mg, 5/7/22 cut 12.5 mg 3/20/22 cut 12.5 mg 10/26/21 cut 6 mg 10/17/21 cut 5 mg, 9/17/21 Cut 3 mg, 9/13/21 cut 4 mg, 8/29/21 Cut 2 mg 8/8/21 Cut 3 mg 7/30/21 Zoloft: Converted 25 mg to liquid. Also take 100 mg pill & 25 mg pill=150 mg total🌞 Feb 28, 2021 0 mg Gapapentin 2021 Gaba each dose 4x/day: Feb 27 7 mg (one dose only), Feb 10, 7 mg, Jan 14 10 mg 2020 Current taper schedule from Aug 30-present: drop 8 mg every 2-3 weeks. Aug 20 31 mg, Aug 18, 33 mg, July 29, 35 mg, July 23 38 mg, July 22 40 mg Jun 24 42 mg, Jun 15 44 mg, Jun 9 48 mg, May 22 50 mg, May 14 54 mg, May 7 56 mg, Apr 16 58 mg, Mar 28 60 mg, Mar 18 62 mg. Feb 26 64 mg. Feb 19, 66 mg. Jan 23, 70 mg. 2019 Dec 19, 72 mg. Nov 14 ,76 mg. Aug 8, 80 mg. Aug 6, 85 mg. Jul 26, 90 mg. Jul 11, 95 mg. Jul 16 trazodone from 100 to 50 mg. Jun 17-July 10 Slowly changed gab fr pill to liquid at same dose 100 mg 4x/d. Apr 24 Stopped klon!!! 🌞 Apr 4 Decreased gaba to 400 mg (100 mg 4x/day)-Apr 4, 2019 0.25 klon March 11 Klonopin .5 mg twice daily, varied dose til Apr 15. Started Klon fast taper 25%, short use Mar 16, 450 mg gaba 3x/day cut 600 mg--not exact!--updose after learning w/d Feb 20, 2019 1800 mg gabapentin; MD taper; off 3 days=mvt disorder & autonomic instability. July 2018 temazepam 15 mg 1-2; prn several x/wk til Jan/Feb 2019 when cold turkey, flu illness for months July 2018 started gabapentin 100 3x/day; titrated up to 1800 mg (600 3x/day) Buspar, I forget how much, 2 pills a day Jan 2017-July 2018 cold turkey. On Zoloft since maybe 2004? After trying many. *I speak from my experience. Nothing I say is medical advice. I'm not a doctor. Link to comment
drugged Posted September 18, 2019 Author Share Posted September 18, 2019 Thanks Rhi, I am a hugger so I'll take all I can get. When I started the buspar I couldn't tell that it was doing anything but I tried a rapid taper years ago and had some withdrawal. The dose I'm taking now (10mg) is down from 60mg/day I was taking several years ago. I'm leaving the venlafaxine at 75mg/morning and 90 beads/early afternoon. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 18, 2019 Author Share Posted September 18, 2019 September 17, 2019 3:30am got up Pain: headache, neck, upper back, shoulders, arms, hands Feelings of malaise, fatigue, apathy, Eyes hurt and burn 100mg tramadol 75mg venlafaxine 20mg omeprazole thyroid meds 8:00am Headache about the same, slight lessening of muscle pain, eyes and mood the same. 2:00pm ate 90 beads venlafaxine 25mg lyrica 10mg buspirone 5:00pm had popcorn and watched some TV Muscle pain (same areas) worsening, very tired 7:00pm 100mg tramadol 8:00pm 50mg trazodone 10mg diazepam 5mg zolpidem 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Nelly Posted September 18, 2019 Share Posted September 18, 2019 (edited) I hope you are doing ok, thinking of you, and this horrible mess that we are in. X Edited September 19, 2019 by ChessieCat removed quote Prescribed Venlafaxine 150mg .......... 19 Feb 2019 stopped Venlafaxine 150mg cold turkey. 06 March 2019 restarted Ven 125mg. 04 April 2019 9 mini pills. 02 May 2019 8 mini pills. 01July 2019 7 mini pills. 18 Aug 2019 6 mini pills. 24 Sept 2019 5.50 mini pills. 11 October 2019 5 mini pills. 5th May 2020 Reinstated Ven 125 mg XR 9 pills. 9th Nov 2020 Update Started splitting dose to twice per day 02/02/2021 can’t stabilise without symptoms. 03/02/21 9 mini pills @ 10am Updated.... July 2021 108mg, Sept 2021 107mg, tapering steps to be updated current dose 14 July 2023 80mg 23.07.23 75mg half way ! Link to comment
drugged Posted September 18, 2019 Author Share Posted September 18, 2019 On 9/17/2019 at 6:15 AM, Happy2Heal said: it will get better I know first hand that beating yourself up is totally counter productive. we all do the best we can with the information we have *at the time*. you've overcome great adversity in your life, draw on your obvious strengths, they'll help you get thru this and so will the members here sending you a virtual hug💕 Thanks for the hug Happy, My first encounter with psychiatric care was around 1974 also. I was 16 and spent a year-and-a-half in and out of psych wards. A result of living in an abusive family. My psychiatrist had me on the heavy-hitter anti-psychotics and antidepressants of the day. Stuff like haldol, mellaril, stelazine, and most of the TCAs. The doctor was abusing me while I was in this doped up state. Lovely man. Anyhow I got out of the whole mess by leaving home when I was 17 and a half, without a high school degree. Got my GED, took the ACTs and started at the state university. Of course I quit all the drugs CT when I left. Absolutely refused to consider any psychotropic med until I was in my mid-30's when a doctor I really liked and trusted told me about the "new" and "safe" SSRIs. It's not often a person can look back over 40 years and say, "Boy, I sure wish I had had the good sense I had when I was 17." 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 18, 2019 Author Share Posted September 18, 2019 45 minutes ago, Nelly said: I hope you are doing ok, thinking of you, and this horrible mess that we are in. X Thank you Nelly. I'm glad you all are here. My situation would be infinitely worse without you folks on this forum. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 19, 2019 Author Share Posted September 19, 2019 September 18, 2019 3:00am got up Pain: upper back, neck, shoulders, arms, upper abdomen Eyes feel irritated and painful 100mg tramadol 75mg venlafaxine 20mg omeprazole thyroid meds 6:00am ate Muscular pain is less, abdominal and eye pain the same Very dysphoric, irritable, frustrated 10:00am meditated for 30 minutes 2:00pm ate 90 beads venlafaxine 10mg buspirone 25mg lyrica 7:00pm Pain in upper body, very tired Eye hurt - painful to keep them open Unable to maintain interest in reading a novel 100mg tramadol 8:00pm 50mg trazodone 10mg diazepam 5mg zolpidem 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 19, 2019 Author Share Posted September 19, 2019 (edited) Antibiotics, tendon damage, and pain. I've been immersing myself in reading articles and research papers about prescription drugs and their side effects. I stumbled across some articles about the fluoroquinolone family of antibiotics and their association with tendon damage. It seems the damage to tendons can come long after the use of the antibiotic. Anyway, for a number of years cipro was my go-to antibiotic. I've always suffered from recurrent UTIs and I always took a packet with me on my trips to visit friends in Mexico. Several years ago I began having a lot of pain in my elbows. I followed my doctor's recommendations but the pain never went away. I never could figure out what I'd done to trigger the original problem but I also noticed that I would get minor overuse injuries from running or swimming and the damage would heal but the pain never really went away. At this point I'm wondering about how, the mechanism by which these antibiotics cause tendon weakness and the mechanisms by which ADs can cause fibromyalgia type chronic pain, could overlap. For awhile those antibiotics were prescribed for everything. Kind of like ADs. Edited September 19, 2019 by ChessieCat removed response from quote 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Moderator Emeritus ChessieCat Posted September 19, 2019 Moderator Emeritus Share Posted September 19, 2019 cipro-levaquin-azithromycin-z-pack-and-other-antibiotics There are several FDA warnings about fluoroquinolone drugs. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
drugged Posted September 20, 2019 Author Share Posted September 20, 2019 September 19, 2019 2:00am Pain woke me; elbows, arms, hands, neck, and stomach 100mg tramadol - drifted into semi-sleep 3:15am got up 75mg venlafaxine 20mg omeprazole thyroid meds 6:30am ate Still sore and achy, tired, 9:30am spouse and I moved furniture and unrolled new area rug, moved furniture back Exhausted 2:00pm ate 90 beads venlafaxine 25mg lyrica 10mg buspirone 3:00pm Back pain - lower and upper, fatigue 8:00pm 100mg tramadol 50mg trazodone 10mg diazepam 5mg zolpidem 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 20, 2019 Author Share Posted September 20, 2019 On 9/15/2019 at 5:25 AM, ChessieCat said: You might have missed this. It below the drug interaction quote. Just thinking here. What do you all think if, after I finish tapering the buspirone, I taper off the zolpidem? The zolpidem definitely knocks me out at night but it leaves me with a noticeable hangover the next morning. I've gone completely off it various times since it was first prescribed without any problems (probably because I take enough other drugs to sedate a horse). Anyway I was thinking about tapering it and leaving the venlafaxine on hold for a bit longer. I have extra zolpidem that I could put away just in case insomnia became a major problem when I start tapering the venlafaxine again, especially when I get down under the 37.5mg dose. From a previous, stone age, attempt to taper the AD, my experience was that I didn't have major problems until I got to a very low dose (I can't remember what that dose was). Then my worst withdrawal effects were akathisia/anxiety and insomnia. I know I can't count on it being the same but I've noticed my body has tendencies to react to some of these drugs in characteristic ways. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
drugged Posted September 20, 2019 Author Share Posted September 20, 2019 September 20, 2019 Lots of pain today. Whole body pain. Also, something that's almost allodynia but it's not painful, just that I can feel everything that touches my skin and it's all irritating. Skin is itchy, too It's been this way since I woke up. This drives me crazy. 1994 Venlafaxine XR 300mg, 2003 tapered, 2004 off briefly back to 37.5 then 75mg, held, June 2019 up to 150mg, Aug.12 tapered down to 112.5mgs, Oct. 21, 2019 96mg; Dec. 8, 2019 90mg, Jan. 8 2020 81mg, Feb. 4, 75mg; April 17, 2023 37.5mg 2003/2004? Diazepam 10mg/bedtime 2013 Lyrica 300mg to 25mg; April 6, 2020 17mg; April 28, <5mg; May 7, 2020 Lyrica 0 mg! 2013 Tramadol 50mg tablets, 200mg/day divided 2005? Trazodone 50mg bedtime, Feb. 12, 2020 40mg, March 7, 25mg; Oct 1 20mg; 0mg! 2009? Zolpidem 5mg at bedtime. Nov. 9, 2019 Zolpidem 0 mg! 1990? Omeprazole 20mg in morning. 2010? Levothyroxine 75mcg morning 2011? Liothyronine 5mcg morning 1999? Buspirone 30mg twice a day August 2019 15mg once a day, Oct.21, 2019 2.5mg evening Oct. 25, 2019 Buspirone 0 mg! Link to comment
Moderator Emeritus ChessieCat Posted September 20, 2019 Moderator Emeritus Share Posted September 20, 2019 (edited) From your drug signature: 1996? Venlafaxine XR to 300mg, to 150mg this June, now tapered down to 112.5mgs, 75 morning, 37.5 evening Does "this June" mean 2019? Please add the year. Thank you. Edited September 20, 2019 by ChessieCat * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
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