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onetime: tapering mirtazipine


onetime

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Hello,

 

I have been on medication for most of my adult life. Over the last 2 years I have been tapering the following:

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

 

So many withdrawal symptoms with windows and waves but the one that is bothering most is hand and finger stiffness, pain and weakness. This seems to be persistent ( no windows) and got worse since starting the mirtazipine taper. 

My question: Is this withdrawal? 

 

I would be grateful to get advice.

 

Thanks in advance.

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator

Hi @onetime,

 

Yes, this symptom is likely withdrawal related. If you search the site you will almost surely find other people with this symptom. I would guess it is from the Quetiapine, which can affect motor control and may result in symptoms like tardive dyskinesia, dystonia, twitches, jerks etc. If you remain abstinent from these drugs this symptom should go away after some indeterminate length of time. Difficult to say when it will improve for any one person.

 

If you are still experiencing symptoms that cause excessive dysfunction or distress, we recommend holding until the symptoms improve, and then beginning to slowly taper again. If you would like some more guidance we would be happy to answer your questions. Some may need to hold for months to see any improvement. Unfortunately withdrawal symptoms can last quite some time once they take hold. This topic on tapering helps explain why. 

 

Is Mirtazapine the only drug you are taking? Are you taking any supplements? Some other drugs can interfere with metabolism and can also have psychotropic effects (antibiotics, steroids, some supplements, coffee, nicotine etc.). It would be very helpful if you could create a drug history in your signature like this one. This link will take you directly to the signature. Signatures generally look like this: 

 

Example:

2001–2002 paroxetine 
2003  citalopram 
2004  paroxetine
2008  paroxetine slow taper down to 2016 Aug off paroxetine
2016  citalopram May 20mg  Oct slow taper down
2018  citalopram 13 Feb 4.6mg 15 Mar 4.4mg 29 Apr 4.2mg

 

This will allow any moderator or member to quickly see your history and where you are in your taper, and thus be able to help more easily without too much reading (most people here are volunteers and have other jobs).

 

Thanks and hope you are feeling better soon. 

Remeron - 2004-2005 (bad withdrawal)

Clonazepam - 2005-2018 (jumped around March)

Olanzapine - 2014- late 2017

Domperidone - 2008-2018

Many drugs in between including Lexapro, other benzos and z-drugs.

Still suffering post-withdrawal from Clonazepam (Klonopin), Olanzapine and Domperidone. 

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Thank you DataGuy,

 

I think I have created my signature:

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

 

Mirtazipine is the only drug I am taking now. To be honest, I am worried that I may have rheumatoid arthritis. However, I do remember having a stiff painfull hand ( just the right hand)on and off when I was tapering quetipine. So I was wondering, do you think the continuous stiff painful hands are from quetipine or mirt withdrawal or both?

 

Thanks again for your help and advice

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator

Thanks @onetime, your signature looks good 👍

 

Yes, I would bet it is from the Quetiapine. Can I ask you what your last dose of that drug was before jumping off? Sometimes symptoms can worsen a bit for a few months after cessation and then flatline for awhile before slowly improving. Some other types of drugs may cause muscle problems in withdrawal as well, though. In the case of Quetiapine, it is likely due to the supersensitization of dopamine receptors as a result of the prolonged blockade of these receptors by the drug. At least that is what psychopharmacologists strongly suspect. See an article like this one, for example.

 

The reason I ask about your last dose is because if someone is tapering 10% per month, they would typically take quite a long time to get off the drug (multiple years). I'm not really sure how long you took to get off, but if you started these drugs only in 2018 and then decided to taper shortly thereafter, you may have gone a bit more quickly in some places. Usually we try to taper hyperbolically, reducing 10% from the previous dose. Sometimes people will read this as reducing from 100mg, to 90mg, to 80mg, to 70mg etc., but it is supposed to be 100mg, 90mg, 81mg, 72mg, 63mg and so on, to avoid greater and greater reductions as a proportion of the last dose. As you get to lower and lower doses, the drug typically dose more work per mg, and dose reductions result in steeper declines in receptor occupancy, which can result in more severe withdrawal symptoms. But you may already be aware of this, I was just making sure. 

 



 

Remeron - 2004-2005 (bad withdrawal)

Clonazepam - 2005-2018 (jumped around March)

Olanzapine - 2014- late 2017

Domperidone - 2008-2018

Many drugs in between including Lexapro, other benzos and z-drugs.

Still suffering post-withdrawal from Clonazepam (Klonopin), Olanzapine and Domperidone. 

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If memory serves my last dose of quetipine would have been:

1/4 of a 25mg tablet mid March 2021

Started Mirt taper on the 13th April 2021 .

 

I started Quetipine taper 100mg Oct.2020. So from 100mg to 0 with duration of:

Oct 2020 to April 2021 i.e. 6 months!!

 

If I could get my head right and believe it is withdrawal and not rheumatoid arthritis, I think that would really help!

 

Thanks again for the advice

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator

Oh yes, I think it must be withdrawal. You did taper fairly quickly. I'm not sure I understand how you got from 100mg to 0mg if you were tapering 10% per month? That seems more like a 20% per month taper. Do you have other symptoms other than just stiff fingers that are clearly withdrawal symptoms? These would be symptoms that you didn't really have before the meds or symptoms that are much more intense than any you had prior to the drug. That would strengthen the case that it is a withdrawal symptom. 

 

As I mentioned before, I think the best thing you can do is hold the dose and wait for your system to catch up with the quick withdrawal (this involves downregulation of dopamine receptors etc.). Continuing to taper can result in worsening withdrawal symptoms like the hand stiffness and muscle weakness. 

Remeron - 2004-2005 (bad withdrawal)

Clonazepam - 2005-2018 (jumped around March)

Olanzapine - 2014- late 2017

Domperidone - 2008-2018

Many drugs in between including Lexapro, other benzos and z-drugs.

Still suffering post-withdrawal from Clonazepam (Klonopin), Olanzapine and Domperidone. 

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20 hours ago, DataGuy said:

Thanks @onetime, your signature looks good 👍

 

Yes, I would bet it is from the Quetiapine. Can I ask you what your last dose of that drug was before jumping off? Sometimes symptoms can worsen a bit for a few months after cessation and then flatline for awhile before slowly improving. Some other types of drugs may cause muscle problems in withdrawal as well, though. In the case of Quetiapine, it is likely due to the supersensitization of dopamine receptors as a result of the prolonged blockade of these receptors by the drug. At least that is what psychopharmacologists strongly suspect. See an article like this one, for example.

 

The reason I ask about your last dose is because if someone is tapering 10% per month, they would typically take quite a long time to get off the drug (multiple years). I'm not really sure how long you took to get off, but if you started these drugs only in 2018 and then decided to taper shortly thereafter, you may have gone a bit more quickly in some places. Usually we try to taper hyperbolically, reducing 10% from the previous dose. Sometimes people will read this as reducing from 100mg, to 90mg, to 80mg, to 70mg etc., but it is supposed to be 100mg, 90mg, 81mg, 72mg, 63mg and so on, to avoid greater and greater reductions as a proportion of the last dose. As you get to lower and lower doses, the drug typically dose more work per mg, and dose reductions result in steeper declines in receptor occupancy, which can result in more severe withdrawal symptoms. But you may already be aware of this, I was just making sure. 

 



 

 

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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Thanks so much for your advice.

 

Yes my maths is off regarding the taper!

 

I have had loads of withdrawal symptoms during my taper from Xanax and Quetipine:

During Waves:

Anxiety

Compulsive googling for answers

Depression

Suicidal Ideation

Hopelessness

Benzo Belly

Muscular Pain

Anger

Short fuse with family

Sleepless nights

and much more

 

Above symptoms not all together and lasting a few days. Windows lasting 1 - 5 weeks on occasions.

 

It is the stiff fingers and painful hands that is lasting for some time i.e. no break, no window. This symptom leading to anxiety, depression and catastrophic thinking.

 

Thanks again DataGuy, I just might need to hold for a time.

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator
On 5/30/2021 at 7:48 AM, onetime said:

Thanks again DataGuy, I just might need to hold for a time.

 

I think that is a good idea, @onetime. It can take quite awhile for protracted withdrawal symptoms to improve, sometimes months or years. You don't need to hold for that long, but you may wish to hold for at least a few weeks, until you are satisfied the symptoms you are experiencing are tolerable. I know it's tough to live with symptoms like that. 

Remeron - 2004-2005 (bad withdrawal)

Clonazepam - 2005-2018 (jumped around March)

Olanzapine - 2014- late 2017

Domperidone - 2008-2018

Many drugs in between including Lexapro, other benzos and z-drugs.

Still suffering post-withdrawal from Clonazepam (Klonopin), Olanzapine and Domperidone. 

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In a strange way DataGuy its comforting that it can take some time for protracted withdrawal symptoms to improve. In other words, it can mean that I am not suffering from an incurable illness like RA! 

I just have another question:

Do you think my taper from Mirtazipine componded withdrawal from Xanax and Quetipine?

 

Thanks for all your help

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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Hello onetime. I just wanted to let you know that I have been getting achy painful hands and fingers while tapering Mirtazapine. These drugs cause inflammation in the body as side effects and withdrawal effects. I am pretty sure this will get better or at least improve a lot once we are off. Marie.

10/13--10/14 Ambien. Started tapering 1/14  Jumped 10/14.  Done.                                                                              

3/14        7.5 Remeron  still taking this.                              

2/14         75 Trazodone   -    Tapered by dry cutting all the way down.

1/16        4 mg Trazodone  -  Jumped. Bad mistake. Got hit with late withdrawal 6 weeks later. Reinstated.

4/16        Reinstated 1 mg, updose to 2 mg Trazodone

2/19        .04 Trazodone. Walked off.  Done.

10/3/19  Started 7.5 Mirtazapine taper cut to .073 gram weight, pill weighs .076

4/5/20    New Mirtazapine Taper - Compound Liquid 7.35 mg April '20, 7.25 mg May, 7.05 mg June, 6.99 mg June, 6.78 mg July, 6.57 mg Aug, Sept 6.35 mg, Sept 6.24 mg, Sept 6.21 mg, Oct 5.99 mg, Oct 5.90 mg, Oct 5.70 mg.

1/11/21 6.05 mg Messed up taper due to syringe change. Must remember the 1 ml syringe contains 1.5mg! 1/16/21 5.99 mg

2/21 5.75 mg, 3/21 5.6 mg, 4/7 5.45, 4/14 5.30, 5/12 5.15, 5/25/21 4.99 mg, 6/29 4.87 mg, 7/14/21 4.74 mg, 8/5 4.62 mg 8/17 4.5 mg, 8/30 4.38 mg,9/16 4.26 mg,10/9 4.14 mg, 10/23 4.05 mg, 11/6 3.96 mg,11/17 3.87mg.***Jan 22 Liquid was changed/couldn't tolerate***Changed back to pills. Feb 22/3.9 mg, 2/17/22 3.8 mg, 3/23 3.7 mg, 4/7 3.6 mg, 5/10 3.5mg,6/10/22 3.4 mg, 7/4 3.3 mg, 7/25 3.2 mg, 8/20/22 3.1 mg, 9/15 3 mg, 10/8/22 2.9 mg., 12/15 2.8 mg, 1/6/23 2.7 mg, 2/16/23 2.6 mg, 3/9 2.5 mg, 4/4 2.4 mg, 4/29/23 2.3 mg, 5/26 2.2 mg, 6/22/23 2.1 mg, 10/14 2 mg, 11/12 1.9 mg, 11/28 1.8 mg ,12/14/23 1.7, 12/31/23 1.6 mg, 1/20 1.5 mg, 2/6/24 1.4 mg, 2/12 updose 1.5 mg, 3/27/24 1.4 mg,5/31/24 l.2 mg. Taking multi-vitamin, vit. D, cholestoff, psyllium husk, and fish oil.

 

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Hi Marie,

 

Thanks for letting me know. I had the itchiness and insomnia the last time I tried to get off Mirtazipine. I have a long way to go. I am cutting the tablets but you seem to be right on the money with your taper procedure. 

 

Thanks for posting. 

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator

@onetime, I'm not sure. It's very possible, but you are probably in a better position to answer that than I am. Did your symptoms worsen after you started the mirtazapine taper? If yes, the mirt taper was probably responsible. There are plenty of factors involved, but generally tapering when your system is already in a state of distress will worsen symptoms. This is why we recommend holding if symptoms are not stable. It can be tough to reverse withdrawal symptoms when they get out of control. 

Remeron - 2004-2005 (bad withdrawal)

Clonazepam - 2005-2018 (jumped around March)

Olanzapine - 2014- late 2017

Domperidone - 2008-2018

Many drugs in between including Lexapro, other benzos and z-drugs.

Still suffering post-withdrawal from Clonazepam (Klonopin), Olanzapine and Domperidone. 

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Thanks DataGuy, Yes the symptoms of painfull stiff fingers occured  after I started the Mirtazipine Taper. I think that it is possible that tapering Xanax, then Quetipine followed by the Mirt taper are all factors. 

I have no problem with withdrawal, once I know it is withdrawal and not something else. 

 

 

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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I've got exactly the same symptoms with my both hand fingers! They are painful and stiff when clenching fists. Now I understand it began when I started taking psychotic drugs, including Quetiapine. I am not tapering yet though.

October 2019 - March 2020 - Trazadone 150 mg

October 2019 - March 2020 - Halcion (triazolamum) 0.25 mg - for sleep

October 2019 - March 2020 - Neurontin (gabapentinum) 300  mg

October 2019 - March 2020 - Lamictal ??

October 2019 - March 2021 - Fluanxol 1 mg

June 2020 - April 2021 - escitalopram 10 mg

March 2020 - April 2021 - Lorafen (lorazepam) 2.5 mg

29.11.2021 - quit coffee CT.

March 2020 - 100 mg Quetiapine, 16.06.2021 90 mg, 16.07.2021 85.5 mg, 13.08.2021 77.5 mg, 10.09.2021 69.3 mg, 08.10.2021 65.8 mg, 29.10.2021 62.5 mg, 13.11.2021 59.4 mg, 06.12.2021

57.9 mg, 13.12.2021 56.5 mg, 20.12.2021 55.0 mg, 27.12.2021 53.5 mg, 03.01.2022 52.1 mg, 10.01.2022 50.8 mg, 17.01.2022 49.5 mg, 24.01.2022 48.3 mg, 31.01.2022 47.1 mg, 07.02.2022 45.5 mg, 14.02.2022 44.0 mg, 21.02.2022 42.9 mg, 28.02.2022 41.5 mg, 07.03.2022 40.0 mg, 14.03.2022 39.0 mg, 21.03.2022 37.0 mg, 04.04.2022 33.3 mg, 25.04.2022 30.0 mg, 15.05.2022 27.0 mg, 03.06.2022 24.3 mg, 24.06.2022 22.0 mg, 13.07.2022 19.8 mg, 01.08.2022 17.0 mg, 15.08.2022 15.3 mg, 01.09.2022 13.8 mg, 15.09.2022 11.5 mg, 01.10.2022 10.0 mg, 15.10.2022 8.0 mg, 01.11.2022 7.0 mg, 22.11.2022 5.5 mg, 11.12.2022 4.0 mg, 16.12.2022 0 mg !

 

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  • 7 months later...

Oral Degenerative Mirtazipine

 

Hello,

 

I was wondering if anyone could help me with the following:

 

I am tapering 15mg of Oral Degenerative Mirtazipine by cutting. Is this okay? I am not accurate with the cuts but it has taking me 6 months to get to 3.5mg with the usual window/ wave pattern.

Is it okay to continue cutting or should I make a water solution and measure with syringe?

 

Please advice when you have a moment.

 

Thanks in advance

 

Edited by ChessieCat
added topic title before merging with intro topic

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • ChessieCat changed the title to onetime: Tapering Mirtazipine
  • Moderator Emeritus

Please read Post #1 of this topic which explains how to get non standard doses.  Please make sure that you read ALL the information in the post.

 

Tips for tapering off mirtazapine (Remeron)

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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Thank you CheesieCat. So it looks like I was doing it right and it's okay to cut the solutab mirt. Just to be double sure: Putting smaller cuts i.e. 1/4 of  15mg into water an using a syringe is okay? Thanks again- like others this has been a long long journey!

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator Emeritus

It would depend on how accurately you can cut up the soltab.

 

I suggest that you post that question in the mirt tips topic and you might get a response from another member tapering that drug.

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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  • Moderator Emeritus

I did a search for the word "soltab" in the Introductions forum and this is the link to the results.  You could visit those members' Introduction topics and see how they tapered.

 

https://www.survivingantidepressants.org/search/?&q=soltab&type=forums_topic&page=1&quick=1&nodes=3&search_and_or=and&sortby=relevancy

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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Thanks so much Chessie,

 

I will check that link.

 

Thanks again

 

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator

@onetime

 

All the reference information I read, you can crush it and weigh it. Then dissolve it in your mouth or water and you can also dissolve it in water and use a syringe to dispense the correct dosage. You just don't want to use any other liquid other than water.

 

Hope that helps.

PREVIOUS medications and discontinuations: Have been on medications since 1996. 

 Valium, Gabapentin, Lamictal, Prilosec and Zantac from 2000 to 2015 with a fast taper by a psychiatrist.

 Liquid Lexapro Nov, 2016 to 31-March, 2019 Lexapro free!!! (total Lexapro taper was 4 years-started with pill form)

---CURRENT MEDICATIONS:Supplements:Milk Thistle, Metamucil, Magnesium Citrate, Vitamin D3, Levothyroxine 25mcg, Vitamin C, Krill oil.

Xanax 1mg 3x day June, 2000 to 19-September, 2020 Went from .150 grams (average weight of 1 Xanax) 3x day to .003 grams 3x day. April 1, 2021 went back on 1mg a day. Started tapering May 19, 2023. July 28, 2023-approximately .87mg. Dr. fast tapered me at the end and realized he messed up. Prescribe it again and I am doing "slower than a turtle" taper.

19-September, 2020 Xanax free!!! (total Xanax taper was 15-1/2 months-1-June, 2019-19-September, 2020)

I am not a medical professional.

The suggestions I make are based on personal experience.

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Thanks Frogie. Like myself, looks like you were on meds for a long time!

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator

@onetime

 

I was on way too long,  longer than you even. But it can be done. 

PREVIOUS medications and discontinuations: Have been on medications since 1996. 

 Valium, Gabapentin, Lamictal, Prilosec and Zantac from 2000 to 2015 with a fast taper by a psychiatrist.

 Liquid Lexapro Nov, 2016 to 31-March, 2019 Lexapro free!!! (total Lexapro taper was 4 years-started with pill form)

---CURRENT MEDICATIONS:Supplements:Milk Thistle, Metamucil, Magnesium Citrate, Vitamin D3, Levothyroxine 25mcg, Vitamin C, Krill oil.

Xanax 1mg 3x day June, 2000 to 19-September, 2020 Went from .150 grams (average weight of 1 Xanax) 3x day to .003 grams 3x day. April 1, 2021 went back on 1mg a day. Started tapering May 19, 2023. July 28, 2023-approximately .87mg. Dr. fast tapered me at the end and realized he messed up. Prescribe it again and I am doing "slower than a turtle" taper.

19-September, 2020 Xanax free!!! (total Xanax taper was 15-1/2 months-1-June, 2019-19-September, 2020)

I am not a medical professional.

The suggestions I make are based on personal experience.

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  • Moderator Emeritus

  

On 4/11/2012 at 10:07 AM, Altostrata said:

 

After making the liquid, I would take the dose immediately and discard the rest -- do not count on it keeping for any length of time.

 

 

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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  • 3 months later...
  • Moderator Emeritus

@onetimeI received your PM but am responding here on your intro thread. That way all of your information is in one place.

 

You mentioned being off all your drugs now for 3 weeks and suffering from itchy skin. This is common, especially after being on drugs such as quetiapine and mirtazapine which both affect histamine.

 

Please let us know more about your taper for all of the drugs and bring us up to speed. It's possible you might benefit from a slight reinstatement, but we need to know more about your taper - the speed of your taper and the dose you stopped at.

 

Also, please update your signature:

 

Account Settings – Create or Edit a signature

 

 

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Thanks Shep. I tapered roughly 10% per month starting with the Xanax then the quetipine and finally the mirt. Took 3 years. I hear you about the reinstatement but would I be okay if I didn't? Just had enough of it all after 3 years. Do I stay away from the antihistamines? I take cetrine antihistamine 10mg just twice so far in the last 2 weeks i.e 1 tablet a week. Thanks again.

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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10 minutes ago, onetime said:

I hear you about the reinstatement but would I be okay if I didn't? Just had enough of it all after 3 years. Do I stay away from the antihistamines? I take cetrine antihistamine 10mg just twice so far in the last 2 weeks i.e 1 tablet a week.

 

I would try a tiny reinstatement of the mirtazapine, perhaps 1 mg since you stopped last month at 1.5 mg. If that helps, it will keep you from continuing to search for other drugs to take in its place.

 

Just a thought. Don't look at reinstating as any type of failure. The goal is to give your body what it needs to feel better.

 

 

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Thanks Shep. I will give it some thought. What is the longest one can go before reinstatement? 

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator Emeritus
35 minutes ago, onetime said:

What is the longest one can go before reinstatement? 

 

Unfortunately we cannot give you the answer to this question because we have seen different results for different people.  However it is generally better to start with a small dose and increase if needed than to risk taking too much.  Please carefully read Post #1 of this topic:

 

About reinstating and stabilizing to reduce withdrawal symptoms

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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Thanks Shep

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator Emeritus

@onetime You have replied as I was posting.

 

Please be sure to read the link that I provided.

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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Thank you Cheesiecat

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • ChessieCat changed the title to onetime: tapering mirtazipine

Hello, I am 5 months off all meds and I am in a real crisis. I reinstated 3.75mg of Mirtazipine 5 days ago because of severe unrelenting anxiety, depression, insomnia, burning all over body pain and off the charts leg pain( can't sit for more then a minute) because pain in the back of both legs gets so bad. I went up to 7.5mg 2 days ago because I got no relief. ( I thought that reinstatement at 3.5 would give me some relief). For the last 5 months insomnia which doesn't really bother me. It's the anxiety lose of appetite and the above symtoms that has me in turmoil. Now I don't know what to do. I am also afraid of kindling ( 25 years of drugs). Do I stay at 7.5mg? Any advice please

 Thank you.

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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  • Moderator Emeritus

I've asked the other staff for their assistance.

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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Thanks CheesieCat

 

Prozac 2000 - 2018

Xanax Quetipine Mirtazipne 2018

Xanax 2mg per day - 10% per month  - finished taper June 2020

Quetipine 100mg per day 10% per month  - finished taper March 2021

Started to taper Mirtazipine 15mg per day 10% per month -started April 2021

Finished taper of 1.5mg approx( cutting with blade) on April 27th 2022. That is I jumped off at 1.5mg.

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