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dudeguyson: Persistent anger after discontinuing Abilify


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I recently did a trial off abilify to to treat depression and suspected bipolar (which has since been ruled out). My dose peeked at (i believe) 20mg and i was on it for approximately two months. While using it I experienced heavy brain fog, a shortened temper, explosive anger and homicidal thoughts, all of which are extremely out of the norm for me as I don't usually get angry. I was also using a fair amount of cannabis at the time as well.

Now 6+ months after tapering my does down under doctor supervision,the side effects have mostly subsided however I am still more prone to anger then before starting abilify and when I get angry its like being on abilify again and the homicidal thoughts come back and i just want to break things and yell at people none of which were really present prior to starting it. 

Does anyone know what could be causing this anger to persist even after going off it?

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  • ChessieCat changed the title to dudeguyson: Persistent anger after discontinuing Abilify
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Welcome to SA. We are a volunteer ran site helping members taper off pschycotic medications, or have tapered off and are healing.


This is your introduction page where you will receive information, ask questions and meet other members. We ask that each member only have one introduction page so we can keep all your information in one place.


First can you please create a signature.


Instructions:  Withdrawal History Signature


It sounds like you had an unpleasant reaction to Abilify. It usually has side effects such as nausea, vomiting, constipation, headache, blurred vision and  dizziness. You also tapered off very quickly. We don't suggest more than 10% a month when doing a taper.


Why taper by 10% of my dosage?


Tips for tapering off aripiprazole (Abilify)


Brain Remodelling


Irritability, Anger, Rage


Brain Remodelling


You could try a small amount of magnesium and omega. They are soothing to the nervous system to some members. If you do, try a small amount of one hold a few days before introducing the other.



Omega-3 Fish Oil


I wish we could tell you how long these side effects will last, but unfortunately we can't as everyone is different. You could try therapy, CBT and lots of self care.


Cognitive Behavior Therapy (CBT) for anxiety, depression


Guided Meditations, Calming Videos, Sleep Hypnosis


If you have any questions after reading these links, please do not hesitate to reach out to us.



PREVIOUS medications and discontinuations: Have been on medications since 1996. 

 Valium, Gabapentin, Lamictal, Prilosec and Zantac from 2000 to 2015 with a fast taper by a psychiatrist.

 Liquid Lexapro Nov, 2016 to 31-March, 2019 Lexapro free!!! (total Lexapro taper was 4 years-started with pill form)

---CURRENT MEDICATIONS:Supplements:Milk Thistle, Metamucil, Magnesium Citrate, Vitamin D3, Levothyroxine 25mcg, Vitamin C, Krill oil.

Xanax 1mg 3x day June, 2000 to 19-September, 2020 Went from .150 grams (average weight of 1 Xanax) 3x day to .003 grams 3x day. April 1, 2021 went back on 1mg a day. Started tapering May 19, 2023. July 28, 2023-approximately .87mg. Dr. fast tapered me at the end and realized he messed up. Prescribe it again and I am doing "slower than a turtle" taper.

19-September, 2020 Xanax free!!! (total Xanax taper was 15-1/2 months-1-June, 2019-19-September, 2020)

I am not a medical professional.

The suggestions I make are based on personal experience.

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