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Manny78: multiple psychotropic drugs - which one first?

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Manny78

My original dose was 20mg and now I am on 18mg.I have been holding at 18mg since march,7th,but dry cutting. My body shakes all the time. I am tempted to take two 10 mg tablets. 

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AliG

Manny. As Gridley already, said Jumping around in doses--you mentioned earlier updosing the Abilify-- in an attempt to get relief is not a good idea . It is much better to keep stability with your dosing. Would you feel comfortable making your own liquid solution?

Edited by AliG

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RubyJ
On ‎3‎/‎27‎/‎2018 at 7:07 AM, Gridley said:

You may be able to make a solution with the Abilify DISCMELT® Orally Disintegrating Tablets (available in 10mg and 15mg dosages); I don't know what the stability would be -- how long the liquid would be good.
 

For general instructions about making your own liquid http://survivingantidepressants.org/index.php?/topic/2693-how-to-make-a-liquid-from-tablets-or-capsules/   

 

 

If you read the topic on making a liquid that Gridley linked earlier, it's okay if the medicine isn't soluble in water, you should still be able to make a liquid. 

 

However, if you prefer cutting tablets, and you're worried about cutting the Discmelt tablets, is there any way you can get a prescription for the regular tablets?  You should be able to cut those, according to the drug information that comes with them.  I don't know if you'd experience symptoms switching from the Discmelt to regular tablets, but I think the way WD works it's probably possible, although you would be getting a stable dose from those and I would think it would even out.  (Mod please correct if wrong.)  There's also a pre-made liquid available, and you could try finding a compounding pharmacy to make you a liquid, too.

 

Since the most immediate thing to try is making your own solution, do you have anyone in your life who could help you make a liquid solution, if it seems like too much to handle right now?  I'm sure you are capable of doing it, but sometimes having someone to help when you're feeling unsure of yourself is a big relief.  It seems like your family isn't supportive of you tapering from reading through your thread, so maybe this isn't a possibility.

 

I'm praying for you and hoping you can find relief.  I'm also trying to taper Abilify and it's not easy, but I have faith we can make it through!

 

Here's the quote about solubility from the above thread:

On ‎7‎/‎26‎/‎2012 at 7:44 PM, Altostrata said:

What if my medication is "insoluble" in water?
About solubility or insolubility, our esteemed member Rhi, who has lab experience, has made many, many homemade liquids:

 

On ‎2‎/‎27‎/‎2013 at 10:30 AM, Rhiannon said:

.... I just wanted to toss in my usual bit on the subject of making preparations for liquid tapering, which is: I personally don't worry about solubility.
 
None of the meds I'm tapering are actually soluble in water. But the pills dissolve into small enough particles that I can stir them up and keep them suspended in water while I measure them out, and that seems to work for me. I stir well before I measure, I stir a little while pipetting them up; I dissolve the pills in glass and pipette out of glass so that I can see visually how evenly everything is suspended, and that's good enough for me.

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RealMe

How are you doing, Manny?  Thinking of you and hoping you are getting some relief.

xo RM

 

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Manny78

Anyone doing water tritation with abilify? I am starting to get more tremors.

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Manny78
On 30/3/2018 at 2:22 AM, RealMe said:

How are you doing, Manny?  Thinking of you and hoping you are getting some relief.

xo RM

 

Hello Real Me. I am so so. I keep having tremors.I just decided to give it a try to water tritation. How are you?

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Manny78
On 28/3/2018 at 4:52 PM, AliG said:

Manny. As Gridley already, said Jumping around in doses--you mentioned earlier updosing the Abilify-- in an attempt to get relief is not a good idea . It is much better to keep stability with your dosing. Would you feel comfortable making your own liquid solution?

AliG, I am doing water tritation now. I started April,1st,2018.

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Manny78
On 28/3/2018 at 5:40 PM, RubyJ said:

 

If you read the topic on making a liquid that Gridley linked earlier, it's okay if the medicine isn't soluble in water, you should still be able to make a liquid. 

 

However, if you prefer cutting tablets, and you're worried about cutting the Discmelt tablets, is there any way you can get a prescription for the regular tablets?  You should be able to cut those, according to the drug information that comes with them.  I don't know if you'd experience symptoms switching from the Discmelt to regular tablets, but I think the way WD works it's probably possible, although you would be getting a stable dose from those and I would think it would even out.  (Mod please correct if wrong.)  There's also a pre-made liquid available, and you could try finding a compounding pharmacy to make you a liquid, too.

 

Since the most immediate thing to try is making your own solution, do you have anyone in your life who could help you make a liquid solution, if it seems like too much to handle right now?  I'm sure you are capable of doing it, but sometimes having someone to help when you're feeling unsure of yourself is a big relief.  It seems like your family isn't supportive of you tapering from reading through your thread, so maybe this isn't a possibility.

 

I'm praying for you and hoping you can find relief.  I'm also trying to taper Abilify and it's not easy, but I have faith we can make it through!

 

Here's the quote about solubility from the above thread:

Thank you, RubyJ. I am not feeling well right now. I will reply when  I feel better.I have pain in my legs and tremors. I started water tritation yesterday.

 

Hugs,

 

Manny

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RealMe
On 4/2/2018 at 2:44 PM, Manny78 said:

Hello Real Me. I am so so. I keep having tremors.I just decided to give it a try to water tritation. How are you?

Good luck with your new protocol.  Hope you get some relief from those awful tremors.  I have tremors also, but they are so much better that I am grateful.  They were pretty awful in the beginning, so I am pulling for you to feel some improvement soon.  I think they were caused by the Abilify although the psychiatrist said they weren't.  I never had them before; and since I stopped the Abilify, they have certainly lessened.  Keep listening to the moderators' suggestions.  I can only imagine where I would be without the guidance here.

xo RM

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RubyJ

Hi Manny.  I'm responding to your comment over here so others reading your thread can see it :)

 

 

On ‎4‎/‎4‎/‎2018 at 9:50 AM, Manny78 said:

Hello rubyj. How are you? It is me,Manny. I think I read that you are liquid tritation abilify. I have anxiety,tremors and body pain. I cant read too much because I don't retain much information. I can't get liquid compound to tritate or regular tablets. As far as I know the ability discmelt disintegrating tablets can be broken. I am tritating using a syringe that measures 10 ml. I toss away 2 ml and drink 8 ml. I don't know how to quote a paragraph.Thank you for your time to help me out.

 

Thank you,

 

Manny

 

 

 

I'm actually tapering from a prescription liquid, not my own liquid, but I'll try to answer your question.  I looked at the 'make your own liquid' thread.  So it sounds like you're making a 1:2 solution (so 10mL water with 20mg Abilify).  What you're doing sounds almost correct then . . . although I think you only toss 1mL to get 18mg total.  Let me do that math . . . 18mg divided by 20mg is 0.9, so that's the percentage of dose you want to take (90%).  90% or 0.9 multiplied by 10mL (your current amount of liquid solution) is 9mL.  So I think you need to be drinking 9mL and tossing 1mL.  Do you follow?  Easier way to math that is to simply divide 18 by 2 (0.5 or your solution ratio -- you have half the amount of liquid to the amount of mg of medicine), and you get 9.

 

I'd say the only other thing to be careful with is making sure the particles are evenly distributed throughout.  A mod might know more.  I hope this method provides some relief for you, although it might take a little time since Abilify has a long half-life.  Keep hanging in there!

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Manny78
26 minutes ago, RubyJ said:

Hi Manny.  I'm responding to your comment over here so others reading your thread can see it :)

 

 

 

I'm actually tapering from a prescription liquid, not my own liquid, but I'll try to answer your question.  I looked at the 'make your own liquid' thread.  So it sounds like you're making a 1:2 solution (so 10mL water with 20mg Abilify).  What you're doing sounds almost correct then . . . although I think you only toss 1mL to get 18mg total.  Let me do that math . . . 18mg divided by 20mg is 0.9, so that's the percentage of dose you want to take (90%).  90% or 0.9 multiplied by 10mL (your current amount of liquid solution) is 9mL.  So I think you need to be drinking 9mL and tossing 1mL.  Do you follow?  Easier way to math that is to simply divide 18 by 2 (0.5 or your solution ratio -- you have half the amount of liquid to the amount of mg of medicine), and you get 9.

 

I'd say the only other thing to be careful with is making sure the particles are evenly distributed throughout.  A mod might know more.  I hope this method provides some relief for you, although it might take a little time since Abilify has a long half-life.  Keep hanging in there!

RubyJ, i am using only 10mg of abilify pill for tritation, but in reality they are two pills,one that disintegrates in my mouth(taking orally) and another 10mg to do water tritation. 10mg orally +8 mg water tritation = 18 mg of abilify. Thank you,

 

Manny

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RubyJ

Oh, I get you.  You're taking one 10mg Discmelt tablet and then dissolving the other one in water.  Then yes, looks like you are on the right track!

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Manny78
On 6/4/2018 at 6:09 PM, RubyJ said:

Oh, I get you.  You're taking one 10mg Discmelt tablet and then dissolving the other one in water.  Then yes, looks like you are on the right track!

Hello,RubyJ. Thank you for time to explain to me the doses. Unfortunately, I can't get liquid abilify, but I think it is the same,liquid abilify suspension or water tritation. I am not very good on math. I am not doing very well with water tritation. I don't know why. I can't go for a walk. I have lower back and hips pain plus some body vibration that doesn t let me do my chores. I don't want to keep  further tapering the abilify. I want to reduce the klonopin but I am scared as hell to switch to a different drug (klonopin).

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brassmonkey

I double checked your math RubyJ and it is correct.  I would like to point out though that the active ingredient in Abilify does not dissolve in water even though the tables or discmelt does.  This makes it very important that things be very well mixed i.e. all the little particles evenly distributed in the water, when the excess is removed.  For future reference with this drug there s a big difference between using a commercially produced oral solution and a homemade water titration.  If you want to switch from one to the other there will need to be some adjustments made to the amount of the dose.

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Manny78
15 hours ago, brassmonkey said:

I double checked your math RubyJ and it is correct.  I would like to point out though that the active ingredient in Abilify does not dissolve in water even though the tables or discmelt does.  This makes it very important that things be very well mixed i.e. all the little particles evenly distributed in the water, when the excess is removed.  For future reference with this drug there s a big difference between using a commercially produced oral solution and a homemade water titration.  If you want to switch from one to the other there will need to be some adjustments made to the amount of the dose.

Brassmonkey, I don't know if you are mentioning me(manny78) or rubyj, can you explain what to do again? English is not my first language.I am doing water tritation not liquid solution. I shake very well my 10ml of water with my abilify 10mg discmelt disintegrating tablets and I toss away 2ml. Right now, I don't know what to do. I know that abilify is not soluble in water,but can I do water tritation?

 

Thank you,

 

Manny

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Manny78
On 5/4/2018 at 2:24 AM, RealMe said:

Good luck with your new protocol.  Hope you get some relief from those awful tremors.  I have tremors also, but they are so much better that I am grateful.  They were pretty awful in the beginning, so I am pulling for you to feel some improvement soon.  I think they were caused by the Abilify although the psychiatrist said they weren't.  I never had them before; and since I stopped the Abilify, they have certainly lessened.  Keep listening to the moderators' suggestions.  I can only imagine where I would be without the guidance here.

xo RM

Thank you,Real Me. I wish healing for you. I hope I get some relief soon. I can't keep following like that.  Are you housebound? I imaging you are. I need to stay at home,but I can't. Hugs. Manny.

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RubyJ

I think the key is trying to wait to stabilize -- if the cause is an uneven dose from cutting the Discmelt tablets -- but I'm not a doctor and I'm unqualified, so I hope someone else has some more suggestions.  If you could talk to a different doctor that might be good?  About the klonopin -- I would read this thread http://survivingantidepressants.org/topic/2207-taking-multiple-psych-drugs-which-drug-to-taper-first/ if you haven't already.

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brassmonkey

" I shake very well my 10ml of water with my abilify 10mg discmelt disintegrating tablets and I toss away 2ml. "

 

That is exactly what you need to do, so keep it up.  If you are going to make any changes, please tell us the details first, so we can double check them.  Don't worry about the other things I wrote. They are general information that I wanted to make note of for others helping you in the future.  I'm sorry to have caused any confusion.

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Manny78
12 hours ago, brassmonkey said:

" I shake very well my 10ml of water with my abilify 10mg discmelt disintegrating tablets and I toss away 2ml. "

 

That is exactly what you need to do, so keep it up.  If you are going to make any changes, please tell us the details first, so we can double check them.  Don't worry about the other things I wrote. They are general information that I wanted to make note of for others helping you in the future.  I'm sorry to have caused any confusion.

Thank you,brassmonkey. No problem. The only thing, I can t get to feel well again since I started tapering abilify. Lots of back back, leg pain that prevent me from doing a normal life. I don t know what to do. I never thought i would be in so much pain from this drug. I have been tritating since april 1st,2018. I can t  even walk for the pain i have in my legs and back.

Thank you to all who read my post.

Manny

 

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Kostas
2 hours ago, Manny78 said:

Thank you,brassmonkey. No problem. The only thing, I can t get to feel well again since I started tapering abilify. Lots of back back, leg pain that prevent me from doing a normal life. I don t know what to do. I never thought i would be in so much pain from this drug. I have been tritating since april 1st,2018. I can t  even walk for the pain i have in my legs and back.

Thank you to all who read my post.

Manny

 

Hi, Manny

I had these leg and back pains from time to time, started during on the ssri and intensified during withdrawal, for no other apparent reason! 

I think that are due to the normalization /upregulation of the serotonin system existing in the peripheral nervous and muscular systems during the drug effects. 

For me is much more bearable now, and I have a lot of periods without any pains compared to the recent past 

Take care. 

 

 

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Manny78

Hello everyone. Do you guys know how to do "water tritation"? I need help developing a taper schedule.

 

Thank you,

 

Manny

 

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ChessieCat

What specifically are you wanting help with?

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Manny78

Hello,cheesiecat. I have been tapering on my own abilify,before dry cut,and now water tritation. I take 8 ml out of 10 ml(toss away 2ml). I want an schedule with my next cut.I want to decrease 5%. I wonder if I have to do it with a cylinder (250ml)or if can be done with a 10ml syringe like I am doing now.I would show you the 10ml syringe,but  I cannot upload a photo because I have used my total mbs of total uploading space.

The syringe mls go like this:

1;1,2;1,4;1,6;1,8;2;2,2 ml and so on. It makes increments of 0,2ml.

 

Thank you,

 

Manny

 

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Manny78

Guys I made a cut from 18ml to 17,75ml. Am I tapering over 10%? Thanks.

Manny

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Gridley

To get 10%, multiply your current dose by .9.  

 

18 X .9 = 16.2.  So you are tapering under 10%.

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DMV64

Hi Manny!

I see you have multiples just like I do. Glad to meet you. How are you today?

-D

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Manny78
2 hours ago, Gridley said:

To get 10%, multiply your current dose by .9.  

 

18 X .9 = 16.2.  So you are tapering under 10%.

Gridley, is the same 10mg of abilify than 10ml of abilify? This is what I did, I tapered abilify dry cut method  to 18mg out of 20mg.now, i take one 10mg abilify pill orally and the other I mix it with water, 10ml. I toss away 2,2ml and drink 7,8 ml of water out of 10ml.

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Manny78
2 hours ago, DMV64 said:

Hi Manny!

I see you have multiples just like I do. Glad to meet you. How are you today?

-D

Hello DMV64. I hate math. I was never good at it.I am not doing very good. I have tremors and inner vibrations. I see that you are tapering and antipsychotic too.

 

Manny

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Gridley

Manny, I have never used liquid so I'm not the best person to answer your question.

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Manny78
6 hours ago, Gridley said:

Manny, I have never used liquid so I'm not the best person to answer your question.

I want to attach a  photo of the water tritation method, but the system doesn t let me upload it. It can be found at this website

 

http://www.benzosupport.org/the_spreadsheet.htm

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Manny78

Hi,guys. I think I got it right,now.I had a friend that explained  to me. If I put a 10mg pill in 10mls of water,and sitirred up,then,

 

1ml of water will contain 1mg of a pill,and

0,25ml of water will contain 0,25mg of pill.

 

What do you guys think? If I toss away 2,2ml of water, and I drink 7,8ml; I am taking 7,8mg of a pill of 10mg?

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brassmonkey

Yes, that's the way it works.

 

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DMV64
On 4/13/2018 at 5:15 PM, Manny78 said:

antipsychotic

Yes, I am. And it is really really hard. Seems this class of meds for me is the BIG BEAR as JanCarol says. It is hard to make it through the day sometimes with the fears and panic, but I do have some good days. I hold onto that.

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RealMe
On 4/15/2018 at 8:48 AM, Manny78 said:

Hi,guys. I think I got it right,now.I had a friend that explained  to me.

Hi Manny78,

Thinking of you and hoping you are doing well.

xo RM

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Manny78

Hello Real Me. How are you? I am doing much better.at least I am not having the inner vibrations like i had two weeks ago. My legs hurt a lot  and i have pain in my belly. Yesterday, i went walking with my friends to the beach. I hope i keep feeling like this. I am doing abilify water tritation. I reduce 0,2ml weekly. Hugs,

Manny.

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RealMe
On 4/23/2018 at 10:04 AM, Manny78 said:

Hello Real Me. How are you? I am doing much better.at least I am not having the inner vibrations like i had two weeks ago. My legs hurt a lot  and i have pain in my belly. Yesterday, i went walking with my friends to the beach. I hope i keep feeling like this. I am doing abilify water tritation. I reduce 0,2ml weekly. Hugs,

Manny.

Hi Manny, I'm so glad to hear you went walking with friends to the beach.  Socializing and walking in nature are excellent activities for healing!  I'm so glad you figured out how to taper.  You're doing so well.  You can be proud of your progress.

xo RM

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