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Pixelchixel: Inability to feel joy post-Paxil


Pixelchixel

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Hello everyone!

I'm a 20 year old woman and I took Paroxetine (40 MG) for five months. I tapered very quickly due to my lack of knowledge at the time. I stopped completely on January 1st 2020. It's now been four weeks since complete cessation of it. 

 

Three days ago I started experiencing a lack of joy, happiness, love, or feeling of attraction to anyone/sex. This caused me to have a mental breakdown which unfortunately may have made things worse as now I feel nothing at all. I also have not eaten due to feeling nauseated by the idea of food and the lack of pleasure associated with eating it.

 

I'm not looking for negativity here. I am not interested in hearing I will be this way forever. I've already been told this and I will not accept it, so please do not try. 

 

Has anyone else gone through this? Is this common? What's the normal timeline? When can I start to expect seeing improvements? 

 

Is there a secret treatment for Anhedonia that I'm unaware of? Google says that there's no treatment except the exact poison I got off of. 

 

Thank you so much for your time and I hope to hear from you soon! 

 

 

Edited by manymoretodays
moved to introductions from S and S care
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  • manymoretodays changed the title to Pixelchixel: Inability to feel joy post-Paxil
  • Moderator Emeritus

Welcome to SA, Pixelchixel.

 

Whoever told you you will be this way forever was wrong.  You will heal.  

 

Lack of pleasure in anything is known as anhedonia and is a very common symptom of withdrawal from psychiatric medications.  Loss of interest in sex is also a very common withdrawal symptom. 

 

 Unfortunately, there is no way to predict how long these symptoms will last, only that they will in time fade away.

 

The symptoms are due to your very fast taper.  We recommend tapering by no more than 10% of current dose every four months.

 

Why taper by 10% of my dosage?

 

What is withdrawal syndrome.

 

Apathy, anhedonia, emotional numbness, emotional anesthesia

 

When we take medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur.

 

Reinstatement of a very small dose of the original drug is the only known way to help alleviate withdrawal syndrome.  The only other alternative is to try and wait out the symptoms and manage as best you can until your central nervous system returns to homeostasis.  Unfortunately no one can give you an exact timeline as to when you will start feeling better and while some do recover relatively easily, for others it can take many months or longer.  

 

Reinstatement isn't a guarantee of diminished symptoms for everyone but it's the best tactic available.  You're still in the time period where reinstatement predictably works, up to 3 months after last dose.  It is best to reinstate as soon as possible after withdrawal symptoms occur. We usually suggest a much smaller reinstatement dose than your last dose.  These drugs are strong, and when reinstating it is better to start with a small amount. Your system has become sensitized and If you take too much it may be too much for your brain and can cause you become unstable.  Later, once you've stabilized on the reinstated dosage, which can take several months,  you can begin a 10% per month taper down to zero.   Please read:

 

About reinstating and stabilizing to reduce withdrawal symptoms. -- at least the first page of the topic

 

If you decide you want to reinstate, I recommend 1mg Paxil--no more.  It takes about 4 days for a dose change to get to get to full state in the blood and a bit longer for it to register in the brain.

 

Do you still have some Paxil?  This link tell you how to get the 1mg you'll need for your reinstatement.

 

Tips for tapering off Paxil (paroxetine)

 

We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. 

 

Magnesium, nature's calcium channel blocker 

 

Omega-3 fatty acids (fish oil) 

 

Add in one at a time and at a low dose in case you do experience problems.

 

This is your Introduction topic, where you can ask questions and connect with other members.  We're glad you found your way here.

 

 

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg Valium 

End 2021  year 1 of Valium taper at 6mg

End 2022 year 2 of Valium taper at 2.75mg 

End 2023 year 3 of Valium taper at 1mg

Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper.

Taper is 95% complete.

 

Imipramine 75 mg daily since 1986.  Jan.-Sept. 2016 tapered to 14.4mg  

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5mg and shift to Valium taper

Jan. 24, 2024: Resume Imipramine taper.  Current dose as of April 1: 6.8mg

Taper is 91% complete.  

  

Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotics, zinc, melatonin .3mg, iron, serrapeptase, nattokinase


I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs.

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Hi Gridley! Thank you for the warm welcome and such enlightening information.

 

I do have a few questions and concerns regarding reinstating to 1mg of Paxil.

 

First of all, I've read that people with anhedonia & lack of interest in sex can get worse after taking the drugs again. I'm terrified to risk causing even more damage. Is this even enough to do more damage? Is this dose so low that it will simply aid my brain in recovery? 

 

Secondly, I'm incredibly fearful that my recovery will be fast & smooth, and that interfering will only further complicate things. If I do start again after the 3 month mark, is that bad? If so, why is that bad? Is the brain mostly healed by month 3? 

 

I can already see these changes affecting my relationships. I'm terrified beyond belief but I really don't want to make things even worse. 

 

Thank you for your time and I hope to hear from you soon! 

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  • Moderator Emeritus
5 hours ago, Pixelchixel said:

 

First of all, I've read that people with anhedonia & lack of interest in sex can get worse after taking the drugs again. I'm terrified to risk causing even more damage. Is this even enough to do more damage? Is this dose so low that it will simply aid my brain in recovery? 

Unfortunately, there are no guarantees in reinstatement.  It can make things worse.  However, you are well within the time frame when reinstatement predictably works (because your brain hasn't had a lot of time to adapt somewhat  to being totally off the drug and as a result is more likely not to react badly to its reintroduction).  1mg is a very low dosage, which also makes it more likely your brain will have a positive rather than negative reaction to it.  1mg is often enough to reduce withdrawal symptoms to a more tolerable level.  It's a matter of your weighing the potential risk versus the potential benefits.  As I said in my first post:

 

"The only other alternative [to reinstatement] is to try and wait out the symptoms and manage as best you can until your central nervous system returns to homeostasis.  Unfortunately no one can give you an exact timeline as to when you will start feeling better and while some do recover relatively easily, for others it can take many months or longer."  We just don't know how long these symptoms will last, and reinstatement is the only known way to alleviate them.

 

5 hours ago, Pixelchixel said:

If I do start again after the 3 month mark, is that bad? If so, why is that bad? Is the brain mostly healed by month 3? 

 

If you're going to reinstate, it's best to do so as soon after you've stopped the drug as possible.  The reason for this is, as I said above, the brain is more receptive to the reintroduction when not a lot of time has passed and the brain is more-or-less in the same condition as it was when you were on the drug.  The farther out in time from when you stopped the drug, the more the brain changes as it adapts to being without the drug, meaning the more chance the result of reinstatement will be negative.  That's the reason for the 3-month mark.  It's not that the brain is mostly healed by that point. We just don't know how much time  in individual cases it will take to heal.  The purpose of the reinstatement is to make that time more tolerable and to allow you to stabilize then taper off that 1mg very, very slowly. 

 

5 hours ago, Pixelchixel said:

I'm terrified beyond belief but I really don't want to make things even worse. 

 

That's the thing about these drugs and the terrible decisions they force us to make.  You don't want to make things worse, but the reinstatement could make things better.  It has helped many people.   I don't want to try to persuade you either way.  

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg Valium 

End 2021  year 1 of Valium taper at 6mg

End 2022 year 2 of Valium taper at 2.75mg 

End 2023 year 3 of Valium taper at 1mg

Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper.

Taper is 95% complete.

 

Imipramine 75 mg daily since 1986.  Jan.-Sept. 2016 tapered to 14.4mg  

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5mg and shift to Valium taper

Jan. 24, 2024: Resume Imipramine taper.  Current dose as of April 1: 6.8mg

Taper is 91% complete.  

  

Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotics, zinc, melatonin .3mg, iron, serrapeptase, nattokinase


I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs.

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