RobertZ Posted March 30, 2023 Author Share Posted March 30, 2023 14 hours ago, Altostrata said: I suspect the taper umasked a quetiapine withdrawal symptom, which also can be a movement disorder. Could be. I'll wait and see how it develops from here and go back to an earlier dose if need be, then retry a slower taper. 14 hours ago, Altostrata said: You're welcome to devise your own taper schedule and method. I am aware this might cause problems. Since I'm at an early stage of my taper, I thought I might get away with a more substantial reduction initially, slowing down further down the line. Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg; Later augmented with quetiapine 75 mg for insomnia; Cold turkeyed all antidepressants in November 2022; Currently on: Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024) Diazepam once every week/two weeks, or less frequently Supplements: magnesium, vit. D3 Link to comment
Administrator Altostrata Posted March 31, 2023 Administrator Share Posted March 31, 2023 14 hours ago, RobertZ said: I am aware this might cause problems. Since I'm at an early stage of my taper, I thought I might get away with a more substantial reduction initially, slowing down further down the line. Obviously, this is not going smoothly. Do it your way if you wish. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
RobertZ Posted May 6, 2023 Author Share Posted May 6, 2023 I'm about to run into a technical problem soon moving to sub-25 mg cuts. Liquid formulations are not available in my country and the smallest 25 mg pills of any IR quetiapine brand that are available all have an enteric coating, so cutting them will not get me the right dose, because the active ingredient will be destroyed by gastric acid before it can be absorbed. I was wondering if taking the cuts with milk would at least partly prevent that from happening by neutralising gastric acid, allowing some time for the quetiapine cut to be absorbed. I would appreciate any suggestion. Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg; Later augmented with quetiapine 75 mg for insomnia; Cold turkeyed all antidepressants in November 2022; Currently on: Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024) Diazepam once every week/two weeks, or less frequently Supplements: magnesium, vit. D3 Link to comment
Administrator Altostrata Posted May 8, 2023 Administrator Share Posted May 8, 2023 Read this This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
RobertZ Posted May 19, 2023 Author Share Posted May 19, 2023 I've woken up gasping for air a few times and had higher-than-usual levels of daytime fatigue as of late. Went through the information leaflet for quetiapine and, sure enough, sleep apnea, muscle weakness and heart problems are listed side effects. I'm so angry at this **** drug. Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg; Later augmented with quetiapine 75 mg for insomnia; Cold turkeyed all antidepressants in November 2022; Currently on: Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024) Diazepam once every week/two weeks, or less frequently Supplements: magnesium, vit. D3 Link to comment
RobertZ Posted June 10, 2023 Author Share Posted June 10, 2023 Good news! I slept an uninterrupted 6 hrs last week, which is a huuge improvement for me. Some days the muscle jerks go completely away and I feel I can fall asleep even without the benzo. I'm having more good days overall and the really bad ones symptom-wise are more spaced out. Things are improving, albeit very slowly. 1 Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg; Later augmented with quetiapine 75 mg for insomnia; Cold turkeyed all antidepressants in November 2022; Currently on: Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024) Diazepam once every week/two weeks, or less frequently Supplements: magnesium, vit. D3 Link to comment
Administrator Altostrata Posted June 11, 2023 Administrator Share Posted June 11, 2023 Have you been taking diazepam every day? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
RobertZ Posted June 11, 2023 Author Share Posted June 11, 2023 I might have forgotten a dose or two (still slept well), but usually I don't skip the diazepam and try to keep things as consistent as possible. Diazepam will go after I'm done with quetiapine. 1 Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg; Later augmented with quetiapine 75 mg for insomnia; Cold turkeyed all antidepressants in November 2022; Currently on: Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024) Diazepam once every week/two weeks, or less frequently Supplements: magnesium, vit. D3 Link to comment
RobertZ Posted September 1, 2023 Author Share Posted September 1, 2023 I haven't posted here in a while as I'm still recovering from an ulnar nerve surgery. Now I can type with both hands and I'm finally able to return to work. As for my taper, I tried doing 10% cuts every 2 weeks, which worked well, until I went from 137,5 mg to 125 mg -- this is where my sleep took a hit. So, I went back up to 137,5 mg and will be staying there for a bit longer to preserve sleep, which I now need for recovery from the surgery. With each reduction. I've been regaining my mental acuity, but I'm still nowhere near as sharp as I had been prior to my "career" as a psychiatric patient. Now I'm only on two low-dose psychotropics but still surprised how stupefying these drugs are. 1 Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg; Later augmented with quetiapine 75 mg for insomnia; Cold turkeyed all antidepressants in November 2022; Currently on: Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024) Diazepam once every week/two weeks, or less frequently Supplements: magnesium, vit. D3 Link to comment
Administrator Altostrata Posted September 2, 2023 Administrator Share Posted September 2, 2023 Please do stabilize before you taper again -- next time, recommend only 5% every 2 weeks or 10% every month. Please let us know how you're doing. 1 This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
RobertZ Posted September 11, 2023 Author Share Posted September 11, 2023 I've noticed some involuntary movements of my arms, face, eyelid and jaw in the morning and I suspect it could be due to taper-induced 'dopamine supersensitivity'. These movements wax and wane, there are weeks when they are almost completely gone, only to come back some time later. Day-time and pre-sleep muscle twitching has become less, but is still present. My neurologist thinks the twichting is drug-induced and has urged me to taper faster. I know that tapering too fast can result in TD, but so can staying on the drug for too long , so I could be screwed either way. Going at 10% per month, it would take ~11 months to complete the taper. This is awfully long and I'm not quite comfortable with that. Every other night, I find it hard to fall asleep and I'm waiting it out before the next cut. The 10% per month rule seems to produce fewer withdrawals than the biweekly cuts I tried earlier, so I'm sticking with the monthly cuts for lack of a better method. My psychiatrist is now on board with my tapering the quetiapine and has prescribed me 25 mg pills to facilitate the process (I was cutting the 100 mg pill into quarters before). This eliminates some of the pill cutting. So, now I take one whole 100 mg, one whole 25 mg and a half of the 25 mg pill. After switching to one whole 25 mg I noticed a worsening of my muscle twitching. This makes me wonder whether the active ingredient is distributed evenly in the pill (I know it's supposed to be, at least in theory) and whether I was getting a different effective dosage when quartering the 100 mg vs now taking one whole 25 mg. Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg; Later augmented with quetiapine 75 mg for insomnia; Cold turkeyed all antidepressants in November 2022; Currently on: Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024) Diazepam once every week/two weeks, or less frequently Supplements: magnesium, vit. D3 Link to comment
Administrator Altostrata Posted September 11, 2023 Administrator Share Posted September 11, 2023 10 hours ago, RobertZ said: My psychiatrist is now on board with my tapering the quetiapine and has prescribed me 25 mg pills to facilitate the process (I was cutting the 100 mg pill into quarters before). Since your psychiatrist is directing your taper, please take any questions or problems to your psychiatrist. Thank you. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
joy2730 Posted September 12, 2023 Share Posted September 12, 2023 21 hours ago, RobertZ said: I've noticed some involuntary movements of my arms, face, eyelid and jaw in the morning and I suspect it could be due to taper-induced 'dopamine supersensitivity'. These movements wax and wane, there are weeks when they are almost completely gone, only to come back some time later. Day-time and pre-sleep muscle twitching has become less, but is still present. My neurologist thinks the twichting is drug-induced and has urged me to taper faster. I know that tapering too fast can result in TD, but so can staying on the drug for too long , so I could be screwed either way. Going at 10% per month, it would take ~11 months to complete the taper. This is awfully long and I'm not quite comfortable with that. Every other night, I find it hard to fall asleep and I'm waiting it out before the next cut. The 10% per month rule seems to produce fewer withdrawals than the biweekly cuts I tried earlier, so I'm sticking with the monthly cuts for lack of a better method. My psychiatrist is now on board with my tapering the quetiapine and has prescribed me 25 mg pills to facilitate the process (I was cutting the 100 mg pill into quarters before). This eliminates some of the pill cutting. So, now I take one whole 100 mg, one whole 25 mg and a half of the 25 mg pill. After switching to one whole 25 mg I noticed a worsening of my muscle twitching. This makes me wonder whether the active ingredient is distributed evenly in the pill (I know it's supposed to be, at least in theory) and whether I was getting a different effective dosage when quartering the 100 mg vs now taking one whole 25 mg. I had completed a quetiapine taper successfully and I noticed the drug is not evenly distributed throughout the pill. I had to do it with only the 100 pills so it is good you have hit the 25 ones. Jan 2023 to July 2023 250mg quetiapine Tapered off quetiapine again over 2 months - now weight problem Link to comment
Jools2816 Posted September 12, 2023 Share Posted September 12, 2023 @RobertZ I am not a doctor, but from what I have learned, it is always about reaching a balance and trade-off is always implicated. I think the risks of tapering too fast are too high to compromise the process. Whilst I understand that is so hard to bear with the symptoms you describe, it might be helpful to wait and stabilise whilst you are monitoring your symptoms. I paid a high price in the past for trying to speed up the process, but we are all different. The distribution of the substance in the drugs varies a lot from one drug to another to my understanding. 1 2002 started Fluoxetine 20 ; increased gradually to 40mg 2004 diagnosed with ADD; prescribed methylphenidate 2004 later in the year methylphenidate aggravated depression so discontinued 2006 tried to taper too quick from AD ( over 3 weeks!) and terrible WD; 2006 later in the year doc changed to Citalopram (dont remember doze) 2009 (circa) as Citalopram did nothing good so back to 40 mg Fluoxetine 2017 due to situational anxiety Pregablin prescribed terrible side effects 201 8 tried again to taper fluoxetine 40 mg with tough WD so back on it 2020 changed to Escitalopram 20mg as no + effect of fluoxetine May 2023 prescribed Modafinil as fatigue intolerable mid July 2023 started tapering - down to 18 mg daily so far so good Link to comment
Administrator Altostrata Posted September 12, 2023 Administrator Share Posted September 12, 2023 7 hours ago, Jools2816 said: The distribution of the substance in the drugs varies a lot from one drug to another to my understanding. The distribution of the active drug in a tablet or capsule is fairly consistent from tablet to tablet or capsule to capsule. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Jools2816 Posted September 12, 2023 Share Posted September 12, 2023 @Altostrata thank you! is this between different types of drugs or it refers to the same type? 2002 started Fluoxetine 20 ; increased gradually to 40mg 2004 diagnosed with ADD; prescribed methylphenidate 2004 later in the year methylphenidate aggravated depression so discontinued 2006 tried to taper too quick from AD ( over 3 weeks!) and terrible WD; 2006 later in the year doc changed to Citalopram (dont remember doze) 2009 (circa) as Citalopram did nothing good so back to 40 mg Fluoxetine 2017 due to situational anxiety Pregablin prescribed terrible side effects 201 8 tried again to taper fluoxetine 40 mg with tough WD so back on it 2020 changed to Escitalopram 20mg as no + effect of fluoxetine May 2023 prescribed Modafinil as fatigue intolerable mid July 2023 started tapering - down to 18 mg daily so far so good Link to comment
Administrator Altostrata Posted September 12, 2023 Administrator Share Posted September 12, 2023 All the tablets and capsules are consistent within brands. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
RobertZ Posted October 3, 2023 Author Share Posted October 3, 2023 An observation: it takes ~5 half-lives (60 hrs or 2-3 days) before my body "notices" a cut and gives me a bout of random muscle jerking and tremors, especially in the morning. Norquetiapine's HL is 12 hrs, so this seems to make sense. I've also noticed the jerks are much less severe and frequent than they used to be. It seems to me this is because the dopamine blockade is trivial at the dosage I'm at right now. Definitely making some progress. Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg; Later augmented with quetiapine 75 mg for insomnia; Cold turkeyed all antidepressants in November 2022; Currently on: Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024) Diazepam once every week/two weeks, or less frequently Supplements: magnesium, vit. D3 Link to comment
Administrator Altostrata Posted October 4, 2023 Administrator Share Posted October 4, 2023 18 hours ago, RobertZ said: It seems to me this is because the dopamine blockade is trivial It may not be trivial, but your nervous system may be somewhat better accommodated to the lower dosage. Good to hear your taper is going fairly well. 1 This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
RobertZ Posted October 24, 2023 Author Share Posted October 24, 2023 I've had some occasional heart palpitations in the midle of the night recently. I don't have them during the day. It's probably related to my recent cut and taking the quetiapine before bed. 10 mg propranolol taken as needed helps. I think I'll stay at 100 mg quet. for a while and see if they stop. 1 Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg; Later augmented with quetiapine 75 mg for insomnia; Cold turkeyed all antidepressants in November 2022; Currently on: Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024) Diazepam once every week/two weeks, or less frequently Supplements: magnesium, vit. D3 Link to comment
Chaos9211 Posted February 27 Share Posted February 27 Hi Robert Just followed your journey so far, since I myself suffer from hypnic jerks albeit I have different medicines, I was wondering how you are going along with your taper and symptoms specially hypnic jerks. 2001 - GAD - Lexapro 10 mg 2010-2016 - Lexapro Dosage increased 40 mg in steps 2019-2020 - Lexapro poop out, rapid tapers and switching to Fluexotine, Effexor, Remeron etc caused severe depression 2021 - ECT sessions to treat Major depressive episodes, discharged from hospital with Effexor 225mg 2021- Pdoc identified OCD as a contributory cause, put me on clomipramine 75 mg and Lithium 1500 mg, stabilized at Clomipramine 75mg and Lithium 800 mg overall high energy state July 2022: Disturbed sleep due to nocturnal panic attacks / hypnic jerks Feb-2023: Valium 5mg added to help with nocturnal panic attacks and insomnia. Taper Timeline Clomipramine: 10/11/23: Taper started 62.5mg 22/1/24: 56.25mg 15/2/24: 50mg 17/3/24: 45 mg Taper Timeline Lithium: 21/2/24: 700mg 29/2/24: 600mg 10/3/24: 800mg(Hold) Taper Timeline Valium: 10/3/24: 3.75mg 25/3/24: 2.5mg Current Meds: Clomipramine 45mg morning, Lithium Carbonate(Neurolith SR) 800 mg ( 400mg Morning 400mg Night), Diazepam (Valium) 2.5mg at Night, Lamotrigine 25mg -> 50mg -> 75mg (8/02-> 21/02 -> 12/03) Pregabalin 125mg at night (25/3/24) Supplements: - Link to comment
RobertZ Posted February 27 Author Share Posted February 27 Hi @Chaos9211, I'm doing much better now, thanks for asking. The jerking has lessened in strength and now it happens less frequently to the point I can sleep well again. It kept getting better the lower I went with the dose, but to see a meaningful improvement, it took longer than I would have liked liked. Regardless, time is a great healer and the only advice I can give you is to trust you will get better eventually, but maybe not as fast as you'd like. 1 Since early March 2022: escitalopram 10 mg + trazodone 75 mg, after a month or so switched to sertraline 50 mg + mianserin 10 mg; Later augmented with quetiapine 75 mg for insomnia; Cold turkeyed all antidepressants in November 2022; Currently on: Quetiapine: 275 mg (21/02/2023; down from 300 mg) -> 250 mg (18/03/2023) -> 225 mg (26/04/2023) -> 200 mg (19/05/2023) -> 187.5 mg (12/06/2023) -> 175 mg (27/06/2023) -> 162.5 mg (16/07/2023) -> 150 mg (31/07/2023) -> 137.5 mg (15/08/2023) -> 125 mg (17/09/2023) -> 112.5 mg (02/10/2023) -> 100 mg (17/10/2023) -> 87.5 mg (05/11/2023) -> 81.25 mg (01/12/2023) -> 75 mg (14/12/2023) -> 68.75 mg (22/12/2023) -> 62.5 mg (28/12/2023) -> 50 mg (11/01/2024) -> 43,75 mg (06/02/2024) -> 37,5 mg (20/02/2024) Diazepam once every week/two weeks, or less frequently Supplements: magnesium, vit. D3 Link to comment
Chaos9211 Posted February 27 Share Posted February 27 Thanks @RobertZ for getting back, its good to hear that you are feeling better and there is light at the end of tunnel for me as well hopefully. 1 2001 - GAD - Lexapro 10 mg 2010-2016 - Lexapro Dosage increased 40 mg in steps 2019-2020 - Lexapro poop out, rapid tapers and switching to Fluexotine, Effexor, Remeron etc caused severe depression 2021 - ECT sessions to treat Major depressive episodes, discharged from hospital with Effexor 225mg 2021- Pdoc identified OCD as a contributory cause, put me on clomipramine 75 mg and Lithium 1500 mg, stabilized at Clomipramine 75mg and Lithium 800 mg overall high energy state July 2022: Disturbed sleep due to nocturnal panic attacks / hypnic jerks Feb-2023: Valium 5mg added to help with nocturnal panic attacks and insomnia. Taper Timeline Clomipramine: 10/11/23: Taper started 62.5mg 22/1/24: 56.25mg 15/2/24: 50mg 17/3/24: 45 mg Taper Timeline Lithium: 21/2/24: 700mg 29/2/24: 600mg 10/3/24: 800mg(Hold) Taper Timeline Valium: 10/3/24: 3.75mg 25/3/24: 2.5mg Current Meds: Clomipramine 45mg morning, Lithium Carbonate(Neurolith SR) 800 mg ( 400mg Morning 400mg Night), Diazepam (Valium) 2.5mg at Night, Lamotrigine 25mg -> 50mg -> 75mg (8/02-> 21/02 -> 12/03) Pregabalin 125mg at night (25/3/24) Supplements: - Link to comment
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