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Venkat: tapering olanzapine / Zyprexa


Venkat

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Hi @hayduke ,hope you are holding well.

 

Some of our fellow travelers here are asking  for the work sheet and video for olanzapine taper.

 

If permissible, and if you feel it could help some, kindly move the below 3 posts on my thread to ' Tips for tapering Zyprexa '

 

Thank you hayduke.

 

 

On 15th June 2020 ,Started to taper 6.25mg olanzapine at the rate of 2.5% of the previous dose every 2 weeks.

13th Nov 2020 - 5mg of olanzapine, 900mg of sodium valproate, 0.25 mg of clonazepam

2020 Dec - 5mg olanzapine, 900mg sodium valproate, 5 mg valium. 

Dec 15th - 5mg olanzapine, 800mg sodium valproate, 4mg valium. 

Jan 11th 2021- 5mg olanzapine, 800mg sodium valproate, 1 mg valium. 

Feb 2nd - 4.88mg olanzapine, 800mg sodium valproate, 0mg valium. 

March 1st- 4.75mg olanzapine, 800mg 

sodium valproate( currently holding SV )

March 9th - 4.63mg olanzapine.April 1st 4.5 April 15th 4.39,1st may 4.27,10thmay 4.16, 20th may 4.05,30th may3.95,15th june3.85, 25th June 3.75, 5th July 3.65, 17th July 3.55, 1st Aug 3.45, 23rd Aug 3.37

6th Sept 3.28, 17th Sept 3.20, 10th Oct 3.12, 21 Oct 3.03 , 1 Nov 2.95 , 11 Nov 2.88,

21 Nov 2.8 , 4 Dec 2.73 , 18 Dec 2.66 , 10 Jan 2022 2.59 , 31 Jan 2.52 , 14 Feb 2.5,1st Apr 2.44,17Apr2.37, 3may2.31, 17may2.25, 30may2.19, 20Jun2.13, 5jul2.07, 1Sept 2.01, 30sept 1.81, 29oct 1.81, 29Nov 1.71. (9dec 0mg of sodium valproate)24Dec1.62, 14Jan23 1.58, 4Feb 1.54, 4Mar 1.46, 4Apr 1.34, 5May 1.26, 2Jun 1.20, 5July1.14, 4Aug 1.08, 19Sept 1.05, 30Sept 1.02, 27Oct 1.0, Dec7 0.97, Jan-4-2024 0.95, Jan20 0.93, Feb16 0.9, Mar1 0.87, Mar16 0.84, 

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36 minutes ago, Venkat said:

Hi @hayduke ,hope you are holding well.

 

Some of our fellow travelers here are asking  for the work sheet and video for olanzapine taper.

 

If permissible, and if you feel it could help some, kindly move the below 3 posts on my thread to ' Tips for tapering Zyprexa '

 

Thank you hayduke.

 

 


Done.  You could've just posted these there directly 🙂

I am not a health professional - your actions are your own.  

Please do not seek tapering support via private message - "Any reason to hold is a good one"

My taper visualised as a graph   |   My intro thread

Backdrop:  2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole

2015: olanzapine  10 -> 7½ -> 6⅔ -> 5mg  by crude pill cutter

2018:  Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold

Jan 2019 2.50mg water titration -> Jan 2020 1.214  -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂

Jun 2023 💉150mg paliperidone "loading" depot shot, 100mg 1wk after Jul 100mg Aug-Dec 75mg/4wks

Jul 2023 2.50mg aripiprazole/day attempt to lower prolactin^

Jan-Feb 2024 cross taper off shots to 1mg risperidone

 

Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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Thanks @hayduke, next time I will try😊

 

On 15th June 2020 ,Started to taper 6.25mg olanzapine at the rate of 2.5% of the previous dose every 2 weeks.

13th Nov 2020 - 5mg of olanzapine, 900mg of sodium valproate, 0.25 mg of clonazepam

2020 Dec - 5mg olanzapine, 900mg sodium valproate, 5 mg valium. 

Dec 15th - 5mg olanzapine, 800mg sodium valproate, 4mg valium. 

Jan 11th 2021- 5mg olanzapine, 800mg sodium valproate, 1 mg valium. 

Feb 2nd - 4.88mg olanzapine, 800mg sodium valproate, 0mg valium. 

March 1st- 4.75mg olanzapine, 800mg 

sodium valproate( currently holding SV )

March 9th - 4.63mg olanzapine.April 1st 4.5 April 15th 4.39,1st may 4.27,10thmay 4.16, 20th may 4.05,30th may3.95,15th june3.85, 25th June 3.75, 5th July 3.65, 17th July 3.55, 1st Aug 3.45, 23rd Aug 3.37

6th Sept 3.28, 17th Sept 3.20, 10th Oct 3.12, 21 Oct 3.03 , 1 Nov 2.95 , 11 Nov 2.88,

21 Nov 2.8 , 4 Dec 2.73 , 18 Dec 2.66 , 10 Jan 2022 2.59 , 31 Jan 2.52 , 14 Feb 2.5,1st Apr 2.44,17Apr2.37, 3may2.31, 17may2.25, 30may2.19, 20Jun2.13, 5jul2.07, 1Sept 2.01, 30sept 1.81, 29oct 1.81, 29Nov 1.71. (9dec 0mg of sodium valproate)24Dec1.62, 14Jan23 1.58, 4Feb 1.54, 4Mar 1.46, 4Apr 1.34, 5May 1.26, 2Jun 1.20, 5July1.14, 4Aug 1.08, 19Sept 1.05, 30Sept 1.02, 27Oct 1.0, Dec7 0.97, Jan-4-2024 0.95, Jan20 0.93, Feb16 0.9, Mar1 0.87, Mar16 0.84, 

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20221229_174713.jpg.4581be5dd7c88c1c6bac

On 15th June 2020 ,Started to taper 6.25mg olanzapine at the rate of 2.5% of the previous dose every 2 weeks.

13th Nov 2020 - 5mg of olanzapine, 900mg of sodium valproate, 0.25 mg of clonazepam

2020 Dec - 5mg olanzapine, 900mg sodium valproate, 5 mg valium. 

Dec 15th - 5mg olanzapine, 800mg sodium valproate, 4mg valium. 

Jan 11th 2021- 5mg olanzapine, 800mg sodium valproate, 1 mg valium. 

Feb 2nd - 4.88mg olanzapine, 800mg sodium valproate, 0mg valium. 

March 1st- 4.75mg olanzapine, 800mg 

sodium valproate( currently holding SV )

March 9th - 4.63mg olanzapine.April 1st 4.5 April 15th 4.39,1st may 4.27,10thmay 4.16, 20th may 4.05,30th may3.95,15th june3.85, 25th June 3.75, 5th July 3.65, 17th July 3.55, 1st Aug 3.45, 23rd Aug 3.37

6th Sept 3.28, 17th Sept 3.20, 10th Oct 3.12, 21 Oct 3.03 , 1 Nov 2.95 , 11 Nov 2.88,

21 Nov 2.8 , 4 Dec 2.73 , 18 Dec 2.66 , 10 Jan 2022 2.59 , 31 Jan 2.52 , 14 Feb 2.5,1st Apr 2.44,17Apr2.37, 3may2.31, 17may2.25, 30may2.19, 20Jun2.13, 5jul2.07, 1Sept 2.01, 30sept 1.81, 29oct 1.81, 29Nov 1.71. (9dec 0mg of sodium valproate)24Dec1.62, 14Jan23 1.58, 4Feb 1.54, 4Mar 1.46, 4Apr 1.34, 5May 1.26, 2Jun 1.20, 5July1.14, 4Aug 1.08, 19Sept 1.05, 30Sept 1.02, 27Oct 1.0, Dec7 0.97, Jan-4-2024 0.95, Jan20 0.93, Feb16 0.9, Mar1 0.87, Mar16 0.84, 

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20221228_221607.thumb.jpg.267dc4c04fb93144b3f7129bd6031efd.jpg

Also

To taper at 5% of the previous dose once a month, follow every 2nd row once a month.

 

To taper at 7.5% of the previous dose once a month, follow every 3rd row once a month.

 

To taper at 10% of the previous dose once a month, follow every 4th row once a month.

 

It can also help in gradual updosing starting from 2.5% of the dose being taken by moving upwards in the table. 

 

On 15th June 2020 ,Started to taper 6.25mg olanzapine at the rate of 2.5% of the previous dose every 2 weeks.

13th Nov 2020 - 5mg of olanzapine, 900mg of sodium valproate, 0.25 mg of clonazepam

2020 Dec - 5mg olanzapine, 900mg sodium valproate, 5 mg valium. 

Dec 15th - 5mg olanzapine, 800mg sodium valproate, 4mg valium. 

Jan 11th 2021- 5mg olanzapine, 800mg sodium valproate, 1 mg valium. 

Feb 2nd - 4.88mg olanzapine, 800mg sodium valproate, 0mg valium. 

March 1st- 4.75mg olanzapine, 800mg 

sodium valproate( currently holding SV )

March 9th - 4.63mg olanzapine.April 1st 4.5 April 15th 4.39,1st may 4.27,10thmay 4.16, 20th may 4.05,30th may3.95,15th june3.85, 25th June 3.75, 5th July 3.65, 17th July 3.55, 1st Aug 3.45, 23rd Aug 3.37

6th Sept 3.28, 17th Sept 3.20, 10th Oct 3.12, 21 Oct 3.03 , 1 Nov 2.95 , 11 Nov 2.88,

21 Nov 2.8 , 4 Dec 2.73 , 18 Dec 2.66 , 10 Jan 2022 2.59 , 31 Jan 2.52 , 14 Feb 2.5,1st Apr 2.44,17Apr2.37, 3may2.31, 17may2.25, 30may2.19, 20Jun2.13, 5jul2.07, 1Sept 2.01, 30sept 1.81, 29oct 1.81, 29Nov 1.71. (9dec 0mg of sodium valproate)24Dec1.62, 14Jan23 1.58, 4Feb 1.54, 4Mar 1.46, 4Apr 1.34, 5May 1.26, 2Jun 1.20, 5July1.14, 4Aug 1.08, 19Sept 1.05, 30Sept 1.02, 27Oct 1.0, Dec7 0.97, Jan-4-2024 0.95, Jan20 0.93, Feb16 0.9, Mar1 0.87, Mar16 0.84, 

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Video of Olanzapine suspension preparation for liquid taper. 

 

https://drive.google.com/file/d/15oSVGHgLUy5xB1TfvdXio9d4C8kU5q4X/view?usp=drivesdk

 

When you are discarding either 1ml ,or 2ml , or 3ml of Olanzapine suspension using a 5ml syringe, instead of 20ml syringe, will be more convenient. 

 

On 15th June 2020 ,Started to taper 6.25mg olanzapine at the rate of 2.5% of the previous dose every 2 weeks.

13th Nov 2020 - 5mg of olanzapine, 900mg of sodium valproate, 0.25 mg of clonazepam

2020 Dec - 5mg olanzapine, 900mg sodium valproate, 5 mg valium. 

Dec 15th - 5mg olanzapine, 800mg sodium valproate, 4mg valium. 

Jan 11th 2021- 5mg olanzapine, 800mg sodium valproate, 1 mg valium. 

Feb 2nd - 4.88mg olanzapine, 800mg sodium valproate, 0mg valium. 

March 1st- 4.75mg olanzapine, 800mg 

sodium valproate( currently holding SV )

March 9th - 4.63mg olanzapine.April 1st 4.5 April 15th 4.39,1st may 4.27,10thmay 4.16, 20th may 4.05,30th may3.95,15th june3.85, 25th June 3.75, 5th July 3.65, 17th July 3.55, 1st Aug 3.45, 23rd Aug 3.37

6th Sept 3.28, 17th Sept 3.20, 10th Oct 3.12, 21 Oct 3.03 , 1 Nov 2.95 , 11 Nov 2.88,

21 Nov 2.8 , 4 Dec 2.73 , 18 Dec 2.66 , 10 Jan 2022 2.59 , 31 Jan 2.52 , 14 Feb 2.5,1st Apr 2.44,17Apr2.37, 3may2.31, 17may2.25, 30may2.19, 20Jun2.13, 5jul2.07, 1Sept 2.01, 30sept 1.81, 29oct 1.81, 29Nov 1.71. (9dec 0mg of sodium valproate)24Dec1.62, 14Jan23 1.58, 4Feb 1.54, 4Mar 1.46, 4Apr 1.34, 5May 1.26, 2Jun 1.20, 5July1.14, 4Aug 1.08, 19Sept 1.05, 30Sept 1.02, 27Oct 1.0, Dec7 0.97, Jan-4-2024 0.95, Jan20 0.93, Feb16 0.9, Mar1 0.87, Mar16 0.84, 

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Tapering Olanzapine from 1 mg to 0.1 mg at the rate of 2.5 % of the previous dose once every two weeks, work sheet table could not be uploaded as it is. Posting the pdf format instead.Olanzepine taper from 1mg downwards_240331_141215.pdf

 

This is in continuation of the previous table where  Olanzapine tapering started from 2.5 mg and stopped at 1.0 mg.

 

Dates to be entered as per ones needs.

 

For withdrawing of additional 0.1ml upto 0.9ml, a 2ml syringe along with the 20ml syringe will be helpful and easy.

On 15th June 2020 ,Started to taper 6.25mg olanzapine at the rate of 2.5% of the previous dose every 2 weeks.

13th Nov 2020 - 5mg of olanzapine, 900mg of sodium valproate, 0.25 mg of clonazepam

2020 Dec - 5mg olanzapine, 900mg sodium valproate, 5 mg valium. 

Dec 15th - 5mg olanzapine, 800mg sodium valproate, 4mg valium. 

Jan 11th 2021- 5mg olanzapine, 800mg sodium valproate, 1 mg valium. 

Feb 2nd - 4.88mg olanzapine, 800mg sodium valproate, 0mg valium. 

March 1st- 4.75mg olanzapine, 800mg 

sodium valproate( currently holding SV )

March 9th - 4.63mg olanzapine.April 1st 4.5 April 15th 4.39,1st may 4.27,10thmay 4.16, 20th may 4.05,30th may3.95,15th june3.85, 25th June 3.75, 5th July 3.65, 17th July 3.55, 1st Aug 3.45, 23rd Aug 3.37

6th Sept 3.28, 17th Sept 3.20, 10th Oct 3.12, 21 Oct 3.03 , 1 Nov 2.95 , 11 Nov 2.88,

21 Nov 2.8 , 4 Dec 2.73 , 18 Dec 2.66 , 10 Jan 2022 2.59 , 31 Jan 2.52 , 14 Feb 2.5,1st Apr 2.44,17Apr2.37, 3may2.31, 17may2.25, 30may2.19, 20Jun2.13, 5jul2.07, 1Sept 2.01, 30sept 1.81, 29oct 1.81, 29Nov 1.71. (9dec 0mg of sodium valproate)24Dec1.62, 14Jan23 1.58, 4Feb 1.54, 4Mar 1.46, 4Apr 1.34, 5May 1.26, 2Jun 1.20, 5July1.14, 4Aug 1.08, 19Sept 1.05, 30Sept 1.02, 27Oct 1.0, Dec7 0.97, Jan-4-2024 0.95, Jan20 0.93, Feb16 0.9, Mar1 0.87, Mar16 0.84, 

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On 3/23/2024 at 9:04 PM, Venkat said:
 

20221228_221607.thumb.jpg.267dc4c04fb93144b3f7129bd6031efd.jpg

 

Tapering Olanzapine from 1 mg to 0.1 mg, work sheet table could not be uploaded as it is. Posting the pdf format instead.Olanzepine taper from 1mg downwards_240331_141215.pdf

 

This is in continuation of the previous table where  Olanzapine tapering started from 2.5 mg and stopped at 1.0 mg.

 

For withdrawing of additional 0.1ml upto 0.9ml, a 2ml syringe along with the 20ml syringe will be helpful and easy.

 

Also

To taper at 5% of the previous dose once a month, follow every 2nd row once a month.

 

To taper at 7.5% of the previous dose once a month, follow every 3rd row once a month.

 

To taper at 10% of the previous dose once a month, follow every 4th row once a month.

 

It can also help in gradual updosing starting from 2.5% of the dose being taken by moving upwards in the table. 

 

 

On 15th June 2020 ,Started to taper 6.25mg olanzapine at the rate of 2.5% of the previous dose every 2 weeks.

13th Nov 2020 - 5mg of olanzapine, 900mg of sodium valproate, 0.25 mg of clonazepam

2020 Dec - 5mg olanzapine, 900mg sodium valproate, 5 mg valium. 

Dec 15th - 5mg olanzapine, 800mg sodium valproate, 4mg valium. 

Jan 11th 2021- 5mg olanzapine, 800mg sodium valproate, 1 mg valium. 

Feb 2nd - 4.88mg olanzapine, 800mg sodium valproate, 0mg valium. 

March 1st- 4.75mg olanzapine, 800mg 

sodium valproate( currently holding SV )

March 9th - 4.63mg olanzapine.April 1st 4.5 April 15th 4.39,1st may 4.27,10thmay 4.16, 20th may 4.05,30th may3.95,15th june3.85, 25th June 3.75, 5th July 3.65, 17th July 3.55, 1st Aug 3.45, 23rd Aug 3.37

6th Sept 3.28, 17th Sept 3.20, 10th Oct 3.12, 21 Oct 3.03 , 1 Nov 2.95 , 11 Nov 2.88,

21 Nov 2.8 , 4 Dec 2.73 , 18 Dec 2.66 , 10 Jan 2022 2.59 , 31 Jan 2.52 , 14 Feb 2.5,1st Apr 2.44,17Apr2.37, 3may2.31, 17may2.25, 30may2.19, 20Jun2.13, 5jul2.07, 1Sept 2.01, 30sept 1.81, 29oct 1.81, 29Nov 1.71. (9dec 0mg of sodium valproate)24Dec1.62, 14Jan23 1.58, 4Feb 1.54, 4Mar 1.46, 4Apr 1.34, 5May 1.26, 2Jun 1.20, 5July1.14, 4Aug 1.08, 19Sept 1.05, 30Sept 1.02, 27Oct 1.0, Dec7 0.97, Jan-4-2024 0.95, Jan20 0.93, Feb16 0.9, Mar1 0.87, Mar16 0.84, 

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