Xcaretuk Posted March 5 Author Share Posted March 5 On 3/3/2024 at 2:32 AM, LostInCanada said: I definitely have to stick to the same brand. If you can get the original one and are confident it will be readily available, that is the way I would go. 1 minute ago, LostInCanada said: @Xcaretuk so this generic brand was new to you from the 20 mg reinstatement? What brand was the 10 mg you were taking? That is the brand I would go back to if possible. I think I did take 10mg of the new brand for awhile, unfortunately I can’t remember exactly how long. When they changed it box looked the same but the name was different. My husband recently looked it up and two companies merged so I don’t know if the product is still the same anyway. Thank you 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Xcaretuk Posted March 5 Author Share Posted March 5 3 hours ago, Xcaretuk said: I think I did take 10mg of the new brand for awhile, unfortunately I can’t remember exactly how long. When they changed it box looked the same but the name was different. My husband recently looked it up and two companies merged so I don’t know if the product is still the same anyway. Thank you Hi Guys, We managed to find out some more info today from the chemist. I was given the new generic Extine by the ‘same’ supplier’ of APX (the prior generic) )at the end of February last year both in a similar box. I wouldn’t have taken this until March at least as I usually get my medication a little in advance. I then started tapering Extine at the end of June as per my signature. So there wasn’t much time in between me starting a new generic before tapering. I also telephoned the Supplier Arrow Pharma here in Australia who said that APX is made in India and Extine in Canada. They said the active ingredient is the same but there maybe different ratios of the inactive ingredients. Do you think I should still cross taper back to APX? Thank you again and sorry for the confusion… 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Administrator Emonda Posted March 6 Administrator Share Posted March 6 Hi @Xcaretuk I've just been chatting offline with another member, and we both thought the same thing. Some of your troubles could be a reaction to jumping back to 20mg from 10mg. You could try a small reduction in the dose and see how you respond. If you notice anything adverse, then you'd need to reconsider. Perhaps 5% may be a reduction you could try...but it's just a best guess. No one knows how you will respond. Let us know what you decide. 1 Please don't send me PMs. I am not a doctor. My comments are based on my personal experience with ADs and tapering. Consult your doctor about your own medical decisions. 2017 – 2022: Vortioxetine 15mg, Jan ’22, 15mg->5mg over 4 weeks, Feb ‘22 5mg -> 7.5mg due to WD, July ’22 6.75mg (found SA website), Aug 6.07mg, Sep 5.46mg, 11 Oct 5.00mg, 18 Oct 4.88mg, 25 Oct 4.75mg, 1 Nov 4.63mg, 8 Nov 4.5mg, 3 Jan ’23 4.39mg, 10 Jan 4.28mg, 17 Jan 4.06mg, 13 Feb 3.95mg, 20 Mar 3.85mg, 3 Apr 3.75mg, 10 April 3.65mg, 31 May 3.58mg, 8 June 3.50mg, 15 June 3.43mg, 22 June 3.35mg, 12 Jul 3.29mg, 19 Jul 3.22mg, 26 Jul 3.15mg, 3 Aug 3.09mg, 30 Aug 3.02mg, 7 Sep 2.96mg, 14 Sep 2.89mg, 21 Sep 2.82mg, Oct 11 2.75mg, Oct 19 2.70mg, Oct 26 2.64mg, Nov 2 2.59mg, Nov 23 2.53mg, Nov 30 2.48mg, 7 Dec 2.43mg, 17 Dec 2.38mg, 19 Jan 2.33mg, 26 Jan 2.28mg, 2 Feb 2.24mg, 8 Feb 2.19mg, 29 Feb 2.15mg, 7 Mar 2.10mg, 14 Mar 2.06mg, 21 Mar 1.99mg, 10 Apr 1.95mg, 17 Apr 1.91mg, 24 Apr 1.87mg, Link to comment
LostInCanada Posted March 6 Share Posted March 6 6 minutes ago, Emonda said: Some of your troubles could be a reaction to jumping back to 20mg This is a good point. I know after my cold turkey I went from 5mg to 10 mg and was a mess. Do you have a scale or access to liquid Paxil? 20 yr+ Paroxetine/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ August 24-29 2022 10mg Prozac/2022.11.28-2022.12.04- 5mg Paroxetine/Dec 5&6/22 10mg Paroxetine/ Dec 8&9/22 10mg Prozac/ 2022.12.07 to 2023.07.01 5mg Paroxetine TAPER 23.07.02-58mgpw/4.9mgai/ 23.07.21-4.8 mg/23.07.28-4.73 mg/23.08.04-4.65 mg/21.09.23-4.58 mg/27.10.23-4.56 mg/5.12.23-4.54 mg/2.1.24-4.52 mg/9.1.24-4.51 mg/17.1.24-4.49 mg/26.1.24-4.47 mg/6.2.24-4.46 mg/19.2.24-4.44mg /4.4.24-4.43mg/28.4.24-4.4mg/ 8am-probiotics/9am-paroxetine, 200mg mag bisglycinate/ 1000mg Vitamin D/noon-1000 mg algae oil (500mg DHA/10mg EPA/620mg Omega 3)/5pm-75 mg DGL/200mg calcium citrate/8pm-.25 mg melatonin "... your strength will be in keeping calm..."-Isaiah 30:15 I am not a medical professional just your peer. The suggestions I give are based on personal experience and/or the well documented experience of others. Link to comment
Xcaretuk Posted March 6 Author Share Posted March 6 4 hours ago, Emonda said: Hi @Xcaretuk I've just been chatting offline with another member, and we both thought the same thing. Some of your troubles could be a reaction to jumping back to 20mg from 10mg. You could try a small reduction in the dose and see how you respond. If you notice anything adverse, then you'd need to reconsider. Perhaps 5% may be a reduction you could try...but it's just a best guess. No one knows how you will respond. Let us know what you decide. Hi @Emonda Thanks for this input. I and my husband think you maybe right after rereading our messy notes. When I was in hospital with my first dangerous hypertensive crisis, bad back and sweating we didn’t connect it to the beginning of withdrawal (we didn’t even mention my tapering to the hospital staff ) but we are now more than certain it was the beginning of WD. I do not have any history of high blood pressure. When the anxiety kicked in I panicked and updosed. That’s when everything became hellish. To think I got away with this in the past… I think I will def give your suggestion some thought and will let you know if I go ahead. I had a slightly better day today, I had more head pressure rather than severe head pain which muddies the waters and made me think perhaps I should wait a bit longer🤷♀️ Thanks again for your advice and time I and my family truly appreciate it. 🌸 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Xcaretuk Posted March 6 Author Share Posted March 6 3 hours ago, LostInCanada said: This is a good point. I know after my cold turkey I went from 5mg to 10 mg and was a mess. Do you have a scale or access to liquid Paxil? Hi @LostInCanada,, Unfortunately we do not have access to liquid here in Australia. However I do have two scales ready to go when required. I am very lucky my husband will be able help me with reductions. The pain is everyday and all day to some degree or other but I had a better day today which tends to muddy the waters a bit so I will see how it goes over the next couple of weeks. I will definitely consider a very small reduction if things do not improve. Every time I have a day where I am bedridden in pain I panic and forget about the other symptoms that have improved somewhat and think it will all never go away. Thank you again for your help and time it really is appreciated 🌸 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
LostInCanada Posted March 6 Share Posted March 6 8 hours ago, Xcaretuk said: I will definitely consider a very small reduction if things do not improve Just do what you feel comfortable with. I am so glad you have a supportive hubby. I was thinking there should be a website just for them. I know some days the worry and stress of it all is alot for my hubby to carry. Give hubby a big hug but a bigger one to yourself. ♥️ 1 20 yr+ Paroxetine/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ August 24-29 2022 10mg Prozac/2022.11.28-2022.12.04- 5mg Paroxetine/Dec 5&6/22 10mg Paroxetine/ Dec 8&9/22 10mg Prozac/ 2022.12.07 to 2023.07.01 5mg Paroxetine TAPER 23.07.02-58mgpw/4.9mgai/ 23.07.21-4.8 mg/23.07.28-4.73 mg/23.08.04-4.65 mg/21.09.23-4.58 mg/27.10.23-4.56 mg/5.12.23-4.54 mg/2.1.24-4.52 mg/9.1.24-4.51 mg/17.1.24-4.49 mg/26.1.24-4.47 mg/6.2.24-4.46 mg/19.2.24-4.44mg /4.4.24-4.43mg/28.4.24-4.4mg/ 8am-probiotics/9am-paroxetine, 200mg mag bisglycinate/ 1000mg Vitamin D/noon-1000 mg algae oil (500mg DHA/10mg EPA/620mg Omega 3)/5pm-75 mg DGL/200mg calcium citrate/8pm-.25 mg melatonin "... your strength will be in keeping calm..."-Isaiah 30:15 I am not a medical professional just your peer. The suggestions I give are based on personal experience and/or the well documented experience of others. Link to comment
Xcaretuk Posted March 7 Author Share Posted March 7 On 3/5/2024 at 10:39 AM, Xcaretuk said: I think I did take 10mg of the new brand for awhile, unfortunately I can’t remember exactly how long. When they changed it box looked the same but the name was different. My husband recently looked it up and two companies merged so I don’t know if the product is still the same anyway. Thank you 9 hours ago, LostInCanada said: Just do what you feel comfortable with. I am so glad you have a supportive hubby. I was thinking there should be a website just for them. I know some days the worry and stress of it all is alot for my hubby to carry. Give hubby a big hug but a bigger one to yourself. ♥️ Yes I feel so bad for my husband, he is my rock. 🙏 2 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Xcaretuk Posted March 10 Author Share Posted March 10 @Emonda@LostInCanada@LotusRising Hi Guys, I thought you maybe interested in this info. Just on the ABC news in Australia 🙏https://www.abc.net.au/news/2024-03-10/challenge-of-tapering-from-antidepressants-australia/103565548?utm_campaign=abc_news_web&utm_content=link&utm_medium=content_shared&utm_source=abc_news_web 2 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Xcaretuk Posted March 13 Author Share Posted March 13 @LotusRising@LostInCanada@Emonda Hi, I have to have a fine needle aspiration on Monday for thyroid nodules. Do I need to be worried about the local anaesthetic? Thank you so much. 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
LostInCanada Posted March 14 Share Posted March 14 @Xcaretuk they should just be using lidocaine which many have had without issue. That is the standard local anesthetic. It's good to ask to make sure especially if there is a choice. 👍 20 yr+ Paroxetine/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ August 24-29 2022 10mg Prozac/2022.11.28-2022.12.04- 5mg Paroxetine/Dec 5&6/22 10mg Paroxetine/ Dec 8&9/22 10mg Prozac/ 2022.12.07 to 2023.07.01 5mg Paroxetine TAPER 23.07.02-58mgpw/4.9mgai/ 23.07.21-4.8 mg/23.07.28-4.73 mg/23.08.04-4.65 mg/21.09.23-4.58 mg/27.10.23-4.56 mg/5.12.23-4.54 mg/2.1.24-4.52 mg/9.1.24-4.51 mg/17.1.24-4.49 mg/26.1.24-4.47 mg/6.2.24-4.46 mg/19.2.24-4.44mg /4.4.24-4.43mg/28.4.24-4.4mg/ 8am-probiotics/9am-paroxetine, 200mg mag bisglycinate/ 1000mg Vitamin D/noon-1000 mg algae oil (500mg DHA/10mg EPA/620mg Omega 3)/5pm-75 mg DGL/200mg calcium citrate/8pm-.25 mg melatonin "... your strength will be in keeping calm..."-Isaiah 30:15 I am not a medical professional just your peer. The suggestions I give are based on personal experience and/or the well documented experience of others. Link to comment
koala Posted March 17 Share Posted March 17 On 3/10/2024 at 11:24 AM, Xcaretuk said: @Emonda@LostInCanada@LotusRising Hi Guys, I thought you maybe interested in this info. Just on the ABC news in Australia 🙏https://www.abc.net.au/news/2024-03-10/challenge-of-tapering-from-antidepressants-australia/103565548?utm_campaign=abc_news_web&utm_content=link&utm_medium=content_shared&utm_source=abc_news_web I found it to be unfortunately a pretty badly written piece that lost some of the issues. But it is great that the hell of AD PWS is getting some airplay. 1 None of my posts are medical advice, just my own experience. Please see your doctor for any medical advice. Overview of drug history: 1991: Prothiaden short stint; 2000 - 2003(?): Nefazodone then paroxetine 2005(?) to 2023: Escitalopram 10mg (with breaks and attempted breaks - see further below) October 2023: Escitalopram 5mg More recent experience quitting escitalopram: Late 2019 - tapered over about 6 weeks - 6 weeks later reinstatement (full dose) taking about 3 weeks to stabilise Late 2021 - tapered over several months to 2mg - held there and then fairly quickly off - 3 months later reinstatement (full dose) taking about 6-8 weeks to stabilise. 2023 - tapered over several months to 1mg then jumped to 0mg on 12 August 2023.September 2023: saw "The Antidepressant Story" and found SA website. 29/9 - reinstatement at 2mg; 10/10 - 5mg; 5/12- 6mg; 11 January 2024 - 10mg; 16 January - 8mg Link to comment
Xcaretuk Posted March 17 Author Share Posted March 17 5 minutes ago, koala said: I found it to be unfortunately a pretty badly written piece that lost some of the issues. But it is great that the hell of AD PWS is getting some airplay. Agree. Thought you might be interested in this piece. https://www1.racgp.org.au/newsgp/clinical/antidepressant-withdrawal-the-hidden-danger 1 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
koala Posted March 17 Share Posted March 17 That’s a much better piece. I will make sure my GPs get it. I will also circulate to friends and family. 1 None of my posts are medical advice, just my own experience. Please see your doctor for any medical advice. Overview of drug history: 1991: Prothiaden short stint; 2000 - 2003(?): Nefazodone then paroxetine 2005(?) to 2023: Escitalopram 10mg (with breaks and attempted breaks - see further below) October 2023: Escitalopram 5mg More recent experience quitting escitalopram: Late 2019 - tapered over about 6 weeks - 6 weeks later reinstatement (full dose) taking about 3 weeks to stabilise Late 2021 - tapered over several months to 2mg - held there and then fairly quickly off - 3 months later reinstatement (full dose) taking about 6-8 weeks to stabilise. 2023 - tapered over several months to 1mg then jumped to 0mg on 12 August 2023.September 2023: saw "The Antidepressant Story" and found SA website. 29/9 - reinstatement at 2mg; 10/10 - 5mg; 5/12- 6mg; 11 January 2024 - 10mg; 16 January - 8mg Link to comment
Xcaretuk Posted March 18 Author Share Posted March 18 This maybe of interest as well. Not sure if you have seen it The Project this week I think. I missed the actual showing it came up on my FB feed this morning. https://fb.watch/qTpm-a4bpd/? 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Administrator Emonda Posted March 18 Administrator Share Posted March 18 Thanks for sharing, Xcaretuk. 1 Please don't send me PMs. I am not a doctor. My comments are based on my personal experience with ADs and tapering. Consult your doctor about your own medical decisions. 2017 – 2022: Vortioxetine 15mg, Jan ’22, 15mg->5mg over 4 weeks, Feb ‘22 5mg -> 7.5mg due to WD, July ’22 6.75mg (found SA website), Aug 6.07mg, Sep 5.46mg, 11 Oct 5.00mg, 18 Oct 4.88mg, 25 Oct 4.75mg, 1 Nov 4.63mg, 8 Nov 4.5mg, 3 Jan ’23 4.39mg, 10 Jan 4.28mg, 17 Jan 4.06mg, 13 Feb 3.95mg, 20 Mar 3.85mg, 3 Apr 3.75mg, 10 April 3.65mg, 31 May 3.58mg, 8 June 3.50mg, 15 June 3.43mg, 22 June 3.35mg, 12 Jul 3.29mg, 19 Jul 3.22mg, 26 Jul 3.15mg, 3 Aug 3.09mg, 30 Aug 3.02mg, 7 Sep 2.96mg, 14 Sep 2.89mg, 21 Sep 2.82mg, Oct 11 2.75mg, Oct 19 2.70mg, Oct 26 2.64mg, Nov 2 2.59mg, Nov 23 2.53mg, Nov 30 2.48mg, 7 Dec 2.43mg, 17 Dec 2.38mg, 19 Jan 2.33mg, 26 Jan 2.28mg, 2 Feb 2.24mg, 8 Feb 2.19mg, 29 Feb 2.15mg, 7 Mar 2.10mg, 14 Mar 2.06mg, 21 Mar 1.99mg, 10 Apr 1.95mg, 17 Apr 1.91mg, 24 Apr 1.87mg, Link to comment
Bailey Posted March 18 Share Posted March 18 On 3/13/2024 at 7:09 PM, Xcaretuk said: I have to have a fine needle aspiration on Monday for thyroid nodules. Do I need to be worried about the local anaesthetic? Thank you so much. How did it go @Xcaretuk? Hugs. 1996 Effexor XR 1996-2012 Prozac and Klonipin 2012: physician took me off Prozac rapidly. Severe (unrecognized) withdrawal. Went inpatient and was poly-drugged -- rapid changes of SSRIs, antipsychotics and benzodiazepines. 2012 Paxil 40mg 2012 Xanax XR 6mg 2019 Xanax XR .5mg (tapered down to this level since being prescribed in 2012) 2014-2022 Gabapentin (tapered down to zero from 1800mg) May 2023 HRT - estriol, estradiol, testosterone, progesterone. Dec. 8, 2023 - stopped progesterone pill (started having awful reactions); inconsistent with estrogen and testosterone combined cream in confusion of severe withdrawal symptoms. Dec. 14, 2023: Estrogen/testosterone cream: Back on about 1/4 amount I was taking previously of estrogen and testosterone cream (1.5 pumps out of 4 -- full amount seemed to ignite some kind of fire in my hyper sensitive state); did not resume progesterone (b/c of bad reactions after taking in WD) December 2022: Paxil 40 to 30mg (went OK); May 2023: Paxil 30 to 20 mg (went OK); Oct. 14, 2023: Paxil 15mg; Oct. 21, 2023: Paxil 10mg Nov. 9, 2023: tried reinstating to 20mg but reacted very badly (kindling?) November 18, 2023: 7.5ml (15mg equivalent) *switch to manufacturer's liquid, Novatium* Conventional psych doc switched me to 7.5ml liquid b/c tiny pills were splitting unevenly - further destabilization by both switching to liquid and changing dose at same time. November 2023 - present: *severe* withdrawal symptoms, akathisia Dec. 6 - manufacturer change on alprazolam er (further destabilization?). Normal mfr very difficult to find now. Jan 6 2024 - stopped coffee and all forms of caffeine. Eliminated dairy, processed foods, sugar. Gluten intolerant so no gluten. Low fodmap diet for gut issues, daily leafy greens, a lot of protein to avoid blood sugar spikes after meals and also for akathisia. Feb 27 2024 - doc had me stop hormone cream. FDA-required formulation had changed and she was worried about my transition to something new. She also said that the estrogen/testosterone hormones are activating. I had already dropped a good bit in dose early in withdrawal (Dec 14 2023 above) b/c it got lost in the chaos of early withdrawal. March 2024 - doctor having me try propranolol for akathisia. First as needed starting around Mar 7 and then daily starting around Mar 23. (aka very bad in morning especially) Apr 2 2024 - stopped propranolol. Think it was interefering with sleep and causing other side effects. May keep on as prn. Link to comment
Xcaretuk Posted March 18 Author Share Posted March 18 11 hours ago, Bailey said: How did it go @Xcaretuk? Hugs. Hi Bailey, I just answered this but now cannot find my comment 😊 They used Lidocaine to wipe across my skin so no injection of a local anaesthetic. They tested two nodules but I had to have 5 needles because they couldn’t get enough of a sample on those attempts. Funny thing was when they put the needle in it made my head pain worse, very strange. I did have some more anxiety first thing this morning with a very mild increase in Akathisia but that probably was just the stress of it. No major increase of withdrawal symptoms so far. How are you coping ? We certainly didn’t expect such a long journey but I try to take each day as it comes and there have been some improvements. Sending hugs right back at you and thank you for asking… 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Bailey Posted March 19 Share Posted March 19 23 hours ago, Xcaretuk said: Hi Bailey, No major increase of withdrawal symptoms so far. I don't like that you had increased pain but it sounds like things went relatively well. I imagine you were relieved not to have the anesthetic as an injection. As for me, I've had some rough days. Hoping tomorrow will be lighter. Big hug to you. 1996 Effexor XR 1996-2012 Prozac and Klonipin 2012: physician took me off Prozac rapidly. Severe (unrecognized) withdrawal. Went inpatient and was poly-drugged -- rapid changes of SSRIs, antipsychotics and benzodiazepines. 2012 Paxil 40mg 2012 Xanax XR 6mg 2019 Xanax XR .5mg (tapered down to this level since being prescribed in 2012) 2014-2022 Gabapentin (tapered down to zero from 1800mg) May 2023 HRT - estriol, estradiol, testosterone, progesterone. Dec. 8, 2023 - stopped progesterone pill (started having awful reactions); inconsistent with estrogen and testosterone combined cream in confusion of severe withdrawal symptoms. Dec. 14, 2023: Estrogen/testosterone cream: Back on about 1/4 amount I was taking previously of estrogen and testosterone cream (1.5 pumps out of 4 -- full amount seemed to ignite some kind of fire in my hyper sensitive state); did not resume progesterone (b/c of bad reactions after taking in WD) December 2022: Paxil 40 to 30mg (went OK); May 2023: Paxil 30 to 20 mg (went OK); Oct. 14, 2023: Paxil 15mg; Oct. 21, 2023: Paxil 10mg Nov. 9, 2023: tried reinstating to 20mg but reacted very badly (kindling?) November 18, 2023: 7.5ml (15mg equivalent) *switch to manufacturer's liquid, Novatium* Conventional psych doc switched me to 7.5ml liquid b/c tiny pills were splitting unevenly - further destabilization by both switching to liquid and changing dose at same time. November 2023 - present: *severe* withdrawal symptoms, akathisia Dec. 6 - manufacturer change on alprazolam er (further destabilization?). Normal mfr very difficult to find now. Jan 6 2024 - stopped coffee and all forms of caffeine. Eliminated dairy, processed foods, sugar. Gluten intolerant so no gluten. Low fodmap diet for gut issues, daily leafy greens, a lot of protein to avoid blood sugar spikes after meals and also for akathisia. Feb 27 2024 - doc had me stop hormone cream. FDA-required formulation had changed and she was worried about my transition to something new. She also said that the estrogen/testosterone hormones are activating. I had already dropped a good bit in dose early in withdrawal (Dec 14 2023 above) b/c it got lost in the chaos of early withdrawal. March 2024 - doctor having me try propranolol for akathisia. First as needed starting around Mar 7 and then daily starting around Mar 23. (aka very bad in morning especially) Apr 2 2024 - stopped propranolol. Think it was interefering with sleep and causing other side effects. May keep on as prn. Link to comment
koala Posted March 19 Share Posted March 19 On 3/18/2024 at 1:57 PM, Xcaretuk said: This maybe of interest as well. Not sure if you have seen it The Project this week I think. I missed the actual showing it came up on my FB feed this morning. https://fb.watch/qTpm-a4bpd/? One of the things troubling me about all these pieces, is that great as it is to have attention on the issue, they all seem to conclude that the most important thing is to keep in touch with your GP - ignoring the fact that lack of knowledge and/or care by GPs is so often what has caused the harm! I noticed one GP proudly recommending in a comment to the piece in the professional journal: “I suggest dose percentage drops to a clinically pragmatic dose for each patient as follows (daily) ---100%, 50% for a week (or over 2 - 3weeks) every 2 days, then 100%, 50%, 50% for a week every 3 days (over 2-3 weeks), i.e. until there is any definite reversal to depression, or not.” None of my posts are medical advice, just my own experience. Please see your doctor for any medical advice. Overview of drug history: 1991: Prothiaden short stint; 2000 - 2003(?): Nefazodone then paroxetine 2005(?) to 2023: Escitalopram 10mg (with breaks and attempted breaks - see further below) October 2023: Escitalopram 5mg More recent experience quitting escitalopram: Late 2019 - tapered over about 6 weeks - 6 weeks later reinstatement (full dose) taking about 3 weeks to stabilise Late 2021 - tapered over several months to 2mg - held there and then fairly quickly off - 3 months later reinstatement (full dose) taking about 6-8 weeks to stabilise. 2023 - tapered over several months to 1mg then jumped to 0mg on 12 August 2023.September 2023: saw "The Antidepressant Story" and found SA website. 29/9 - reinstatement at 2mg; 10/10 - 5mg; 5/12- 6mg; 11 January 2024 - 10mg; 16 January - 8mg Link to comment
Xcaretuk Posted March 19 Author Share Posted March 19 1 minute ago, koala said: One of the things troubling me about all these pieces, is that great as it is to have attention on the issue, they all seem to conclude that the most important thing is to keep in touch with your GP - ignoring the fact that lack of knowledge and/or care by GPs is so often what has caused the harm! I noticed one GP proudly recommending in a comment to the piece in the professional journal: “I suggest dose percentage drops to a clinically pragmatic dose for each patient as follows (daily) ---100%, 50% for a week (or over 2 - 3weeks) every 2 days, then 100%, 50%, 50% for a week every 3 days (over 2-3 weeks), i.e. until there is any definite reversal to depression, or not.” I agree with all that you have said and that comment from the GP is no surprise. Unfortunately we are only at the beginning of a campaign that will be a fight to win. But we have to keep at it. I am hoping when I feel better I can do more to raise awareness… 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Xcaretuk Posted March 25 Author Share Posted March 25 @LotusRising@LostInCanada@Emonda Hi, I am sorry to be a nuisance I just needed to let off some emotion today. I feel exhausted with this head pain it doesn’t seem to be improving. 4 months since it started and it comes with sore eyes and upper back pain. I had a reasonable (more pressure and no pain until the evening) day the other day and it gets me hopeful then it comes back again with a vengeance the next day. It’s all around my temples, eyes and forehead. I know I am fortunate to have some things improve such as the Akathisia which is now milder first thing in the morning. I still wake up at the same time 12.30am but without the electrical tingling and going through my body. I still have hot sweats and upper back pain. But it’s the head pain everyday that is wearing me down. I have had an MRI that showed some small vessel ischaemic changes apparently consistent with age related changes so pretty much normal. This particular pain def started with the up dose. I haven’t made any changes to the dose as I am too scared and I am hoping it gets better in a few months as I know @LostInCanada yours took 7 months. This is the only symptom that doesn’t appear to have improved and I am scared it will stay because of this. It’s been such a traumatic ride what with the hypertensive crisis during the beginning of withdrawal ( I had 6 people working on me with the first one) and then the terrifying terror, Akathisia, head pain etc that started after the up dose. I am so sorry I know you can’t help me anymore than you have done and I am lucky that some of my symptoms have improved but this pain relentness. Thank you for listening. 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
LostInCanada Posted March 25 Share Posted March 25 @Xcaretuk I know it really wears a person down. It will get better. Does aromatherapy help-mint or lavender? Do cold compresses or steam/hot bath? I totally relate to the back pain and head pressure. Mine comes and goes though. It too will improve but for you it sounds like a stubborn one. ❤️🙏 1 20 yr+ Paroxetine/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ August 24-29 2022 10mg Prozac/2022.11.28-2022.12.04- 5mg Paroxetine/Dec 5&6/22 10mg Paroxetine/ Dec 8&9/22 10mg Prozac/ 2022.12.07 to 2023.07.01 5mg Paroxetine TAPER 23.07.02-58mgpw/4.9mgai/ 23.07.21-4.8 mg/23.07.28-4.73 mg/23.08.04-4.65 mg/21.09.23-4.58 mg/27.10.23-4.56 mg/5.12.23-4.54 mg/2.1.24-4.52 mg/9.1.24-4.51 mg/17.1.24-4.49 mg/26.1.24-4.47 mg/6.2.24-4.46 mg/19.2.24-4.44mg /4.4.24-4.43mg/28.4.24-4.4mg/ 8am-probiotics/9am-paroxetine, 200mg mag bisglycinate/ 1000mg Vitamin D/noon-1000 mg algae oil (500mg DHA/10mg EPA/620mg Omega 3)/5pm-75 mg DGL/200mg calcium citrate/8pm-.25 mg melatonin "... your strength will be in keeping calm..."-Isaiah 30:15 I am not a medical professional just your peer. The suggestions I give are based on personal experience and/or the well documented experience of others. Link to comment
Xcaretuk Posted March 25 Author Share Posted March 25 1 minute ago, LostInCanada said: @Xcaretuk I know it really wears a person down. It will get better. Does aromatherapy help-mint or lavender? Do cold compresses or steam/hot bath? I totally relate to the back pain and head pressure. Mine comes and goes though. It too will improve but for you it sounds like a stubborn one. ❤️🙏 Thank you. Just needed to vent while having a little cry today. I’ve tried cold compresses but I haven’t tried aromatherapy so I might give that a go. 🙏 1 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Administrator Emonda Posted March 25 Administrator Share Posted March 25 Yeah, the process is not nice at all. I am glad, however, to read that some things have improved...got to celebrate even the smallest improvement. 1 Please don't send me PMs. I am not a doctor. My comments are based on my personal experience with ADs and tapering. Consult your doctor about your own medical decisions. 2017 – 2022: Vortioxetine 15mg, Jan ’22, 15mg->5mg over 4 weeks, Feb ‘22 5mg -> 7.5mg due to WD, July ’22 6.75mg (found SA website), Aug 6.07mg, Sep 5.46mg, 11 Oct 5.00mg, 18 Oct 4.88mg, 25 Oct 4.75mg, 1 Nov 4.63mg, 8 Nov 4.5mg, 3 Jan ’23 4.39mg, 10 Jan 4.28mg, 17 Jan 4.06mg, 13 Feb 3.95mg, 20 Mar 3.85mg, 3 Apr 3.75mg, 10 April 3.65mg, 31 May 3.58mg, 8 June 3.50mg, 15 June 3.43mg, 22 June 3.35mg, 12 Jul 3.29mg, 19 Jul 3.22mg, 26 Jul 3.15mg, 3 Aug 3.09mg, 30 Aug 3.02mg, 7 Sep 2.96mg, 14 Sep 2.89mg, 21 Sep 2.82mg, Oct 11 2.75mg, Oct 19 2.70mg, Oct 26 2.64mg, Nov 2 2.59mg, Nov 23 2.53mg, Nov 30 2.48mg, 7 Dec 2.43mg, 17 Dec 2.38mg, 19 Jan 2.33mg, 26 Jan 2.28mg, 2 Feb 2.24mg, 8 Feb 2.19mg, 29 Feb 2.15mg, 7 Mar 2.10mg, 14 Mar 2.06mg, 21 Mar 1.99mg, 10 Apr 1.95mg, 17 Apr 1.91mg, 24 Apr 1.87mg, Link to comment
Xcaretuk Posted March 25 Author Share Posted March 25 51 minutes ago, Emonda said: Yeah, the process is not nice at all. I am glad, however, to read that some things have improved...got to celebrate even the smallest improvement. Thanks you are right. 🙏 1 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Xcaretuk Posted March 29 Author Share Posted March 29 @LostInCanada@LotusRising@Emonda Hi, I have had a shocking day for nerve pain yet again in my forehead and back of eyes. My husband and I after looking back on your suggestions are thinking of reducing the dose by 1mg over a month ( to be on the safe side) to see if that would help a little. We are thinking of the following steps: 1. Weigh the tablet (20mg) in solid form. 2. Crush the tablet into a powder 3. Remove the required amount of powder for that days dosage for example day 1 of a 30 day month would be 1/30 of 1mg (0.033). 4. Dispense powder into a glass of water stirring waiting for it to dissolve. 5. Once dissolved drink all water with dissolved tablet inside. 6. Then refill the glass with water and drink it to ensure all powder has been taken. 7. The next day remove 2/30 (.066mg) of 1mg and the follow above steps. By the end of the month we would have reduced the dosage by 1 mg. Does this sound correct to you? Thank you so much again for all your help. We are so grateful. 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Administrator Emonda Posted March 29 Administrator Share Posted March 29 Hi Xcaretuk, Sorry to hear you've had a bad day. The logic is reasonable, and it is certainly a very slow start to tapering. It's prudent to carefully test the waters. My only question is will your scale measure accurately to that level? I can't remember if I told you, but this is what I do: Crush a tablet between two spoons. Then, pulverise it into fine powder using the tip of one spoon against the other spoon. Add the contents into a large syringe, Add 10ml of water and shake vigorously, Extract what I don't need with a 0.5ml syringe (buy them online and remove the needle). If you were to test the water with a 2% reduction, you'd remove 0.2ml. I reckon it'd be too hard to reduce by less unless you added more water, say, 20ml. Drink the remaining liquid from the large syringe, then fill it with water again and drink that too, just in case something was left behind. Can your tablets be crushed and converted to liquid? My copy of the Maudsley Deprescribing Guidelines says that Paroxetine immediate release tables can be mixed with water. Are your tablets immediately release? I'm not a doctor nor a compounding chemist...I'm just letting you know what works for me. You need to make your own decisions with this. You could use a compounding chemist, although it would significantly increase the cost of the medication for you. Also, from memory, LostinCanada found her compounding chemist prepared doses varied by +-10%. I'm sure LostinCanada may have some wisdom from personal experience with this drug when it's daytime on her side of the world. I hope this helps. Emonda Please don't send me PMs. I am not a doctor. My comments are based on my personal experience with ADs and tapering. Consult your doctor about your own medical decisions. 2017 – 2022: Vortioxetine 15mg, Jan ’22, 15mg->5mg over 4 weeks, Feb ‘22 5mg -> 7.5mg due to WD, July ’22 6.75mg (found SA website), Aug 6.07mg, Sep 5.46mg, 11 Oct 5.00mg, 18 Oct 4.88mg, 25 Oct 4.75mg, 1 Nov 4.63mg, 8 Nov 4.5mg, 3 Jan ’23 4.39mg, 10 Jan 4.28mg, 17 Jan 4.06mg, 13 Feb 3.95mg, 20 Mar 3.85mg, 3 Apr 3.75mg, 10 April 3.65mg, 31 May 3.58mg, 8 June 3.50mg, 15 June 3.43mg, 22 June 3.35mg, 12 Jul 3.29mg, 19 Jul 3.22mg, 26 Jul 3.15mg, 3 Aug 3.09mg, 30 Aug 3.02mg, 7 Sep 2.96mg, 14 Sep 2.89mg, 21 Sep 2.82mg, Oct 11 2.75mg, Oct 19 2.70mg, Oct 26 2.64mg, Nov 2 2.59mg, Nov 23 2.53mg, Nov 30 2.48mg, 7 Dec 2.43mg, 17 Dec 2.38mg, 19 Jan 2.33mg, 26 Jan 2.28mg, 2 Feb 2.24mg, 8 Feb 2.19mg, 29 Feb 2.15mg, 7 Mar 2.10mg, 14 Mar 2.06mg, 21 Mar 1.99mg, 10 Apr 1.95mg, 17 Apr 1.91mg, 24 Apr 1.87mg, Link to comment
Xcaretuk Posted March 29 Author Share Posted March 29 On 3/18/2024 at 9:49 PM, Bailey said: How did it go @Xcaretuk? Hugs. 20 minutes ago, Emonda said: Hi Xcaretuk, Sorry to hear you've had a bad day. The logic is reasonable, and it is certainly a very slow start to tapering. It's prudent to carefully test the waters. My only question is will your scale measure accurately to that level? I can't remember if I told you, but this is what I do: Crush a tablet between two spoons. Then, pulverise it into fine powder using the tip of one spoon against the other spoon. Add the contents into a large syringe, Add 10ml of water and shake vigorously, Extract what I don't need with a 0.5ml syringe (buy them online and remove the needle). If you were to test the water with a 2% reduction, you'd remove 0.2ml. I reckon it'd be too hard to reduce by less unless you added more water, say, 20ml. Drink the remaining liquid from the large syringe, then fill it with water again and drink that too, just in case something was left behind. Can your tablets be crushed and converted to liquid? My copy of the Maudsley Deprescribing Guidelines says that Paroxetine immediate release tables can be mixed with water. Are your tablets immediately release? I'm not a doctor nor a compounding chemist...I'm just letting you know what works for me. You need to make your own decisions with this. You could use a compounding chemist, although it would significantly increase the cost of the medication for you. Also, from memory, LostinCanada found her compounding chemist prepared doses varied by +-10%. I'm sure LostinCanada may have some wisdom from personal experience with this drug when it's daytime on her side of the world. I hope this helps. Emonda 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Xcaretuk Posted March 29 Author Share Posted March 29 28 minutes ago, Emonda said: Hi Xcaretuk, Sorry to hear you've had a bad day. The logic is reasonable, and it is certainly a very slow start to tapering. It's prudent to carefully test the waters. My only question is will your scale measure accurately to that level? I can't remember if I told you, but this is what I do: Crush a tablet between two spoons. Then, pulverise it into fine powder using the tip of one spoon against the other spoon. Add the contents into a large syringe, Add 10ml of water and shake vigorously, Extract what I don't need with a 0.5ml syringe (buy them online and remove the needle). If you were to test the water with a 2% reduction, you'd remove 0.2ml. I reckon it'd be too hard to reduce by less unless you added more water, say, 20ml. Drink the remaining liquid from the large syringe, then fill it with water again and drink that too, just in case something was left behind. Can your tablets be crushed and converted to liquid? My copy of the Maudsley Deprescribing Guidelines says that Paroxetine immediate release tables can be mixed with water. Are your tablets immediately release? I'm not a doctor nor a compounding chemist...I'm just letting you know what works for me. You need to make your own decisions with this. You could use a compounding chemist, although it would significantly increase the cost of the medication for you. Also, from memory, LostinCanada found her compounding chemist prepared doses varied by +-10%. I'm sure LostinCanada may have some wisdom from personal experience with this drug when it's daytime on her side of the world. I hope this helps. Emonda Thanks Emonda for your quick response. Yes it’s an immediate release tablet. Yes you’re right about the scale I think my husband says it only goes to 0.001g. Thanks for your thoughts. Would we be correct to assume when you add the 10ml of water to the crushed tablet in the syringe does the tablet fully dissolve and the volume of water/solution remains at 10ml ? We just wish to take a tiny bit off to see if it will relieve the pain as it’s been everyday for over 4 months. 🙏 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
LostInCanada Posted March 29 Share Posted March 29 @Xcaretuk it isn't advisable to go directly from using pill form to liquid. It absorbs at a different rate and can throw your system out. My suggestion is to weigh 10 pills together and then divide that weight by 10. That will give you the actual pill weight for 20 mg of drug to use as your standard. (As long as you remain with the same manufacturer and they make no changes and you continue to use the 20 mg pill size) It is easier to shave off a small amount of the pill with a one sided razor(from a hardware store) then trying to weigh powder. Then you will be able to continue taking the pill without adding liquid and more instability. 20 yr+ Paroxetine/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ August 24-29 2022 10mg Prozac/2022.11.28-2022.12.04- 5mg Paroxetine/Dec 5&6/22 10mg Paroxetine/ Dec 8&9/22 10mg Prozac/ 2022.12.07 to 2023.07.01 5mg Paroxetine TAPER 23.07.02-58mgpw/4.9mgai/ 23.07.21-4.8 mg/23.07.28-4.73 mg/23.08.04-4.65 mg/21.09.23-4.58 mg/27.10.23-4.56 mg/5.12.23-4.54 mg/2.1.24-4.52 mg/9.1.24-4.51 mg/17.1.24-4.49 mg/26.1.24-4.47 mg/6.2.24-4.46 mg/19.2.24-4.44mg /4.4.24-4.43mg/28.4.24-4.4mg/ 8am-probiotics/9am-paroxetine, 200mg mag bisglycinate/ 1000mg Vitamin D/noon-1000 mg algae oil (500mg DHA/10mg EPA/620mg Omega 3)/5pm-75 mg DGL/200mg calcium citrate/8pm-.25 mg melatonin "... your strength will be in keeping calm..."-Isaiah 30:15 I am not a medical professional just your peer. The suggestions I give are based on personal experience and/or the well documented experience of others. Link to comment
Xcaretuk Posted March 29 Author Share Posted March 29 6 hours ago, LostInCanada said: @Xcaretuk it isn't advisable to go directly from using pill form to liquid. It absorbs at a different rate and can throw your system out. My suggestion is to weigh 10 pills together and then divide that weight by 10. That will give you the actual pill weight for 20 mg of drug to use as your standard. (As long as you remain with the same manufacturer and they make no changes and you continue to use the 20 mg pill size) It is easier to shave off a small amount of the pill with a one sided razor(from a hardware store) then trying to weigh powder. Then you will be able to continue taking the pill without adding liquid and more instability. Thank you @LostInCanada Out of interest would that be the same for a compounded liquid? I think if we do it we will stick with what you are suggesting as I only want to try a very small drop to see if it relieves the pain. Then cross taper to liquid at a later date when I do a proper taper. It’s such a strange awful pain stinging behind my eyes, forehead and temple. It also wakes me up in the night always at around 12.30am after a dream and 4.30am and sometimes is accompanied by a tingle down my back and arms. It’s everyday and all day some days being slightly better with more pressure than pain it makes my eyes irritated and painful. It hasn’t got any better in regard to having more slightly better days than bad. Which makes you think it’s never going to go away (I think most of us have probably thought that at one time or other with one symptom or another) I am still getting hot sweats on and off in the day and mild Akathisia in morning. I still have sensitivity to noise especially in the morning. Unfortunately I also still can’t socialise (was very social before this) as it’s too overwhelming especially when in pain. I can’t believe how long it takes to stabilise since the withdrawal symptoms last September and the horrific up-dose symptoms that started in November. Thanks again I will update you if and when I start. 🙏 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
LostInCanada Posted March 30 Share Posted March 30 1 hour ago, Xcaretuk said: Out of interest would that be the same for a compounded liquid Yes, this would be the same. Once you stabilize, there is a protocol for slowly transitioning to liquid if you want to. It would be 1/4 of liquid dose with 3/4 pill, then 1/2 and 1/2, then 3/4 and 1/4 and finally all liquid. This would be done over a couple weeks. 1 hour ago, Xcaretuk said: Unfortunately I also still can’t socialise I was the same and can now do about an hour with my mom or daughter. 10 minutes on the street with a friend, otherwise I am so activated- crying and shaking. So it is slowly getting better after 1.5 years. 1 hour ago, Xcaretuk said: pressure than pain it makes my eyes irritated and painful. Paroxetine affects eye sight and can even cause glaucoma. Have you had your eye pressure checked at the optometrist? Be aware to avoid dilation drops as they are anticholinergic. I get similar pressure/pain though not as intense or long lasting. I've been checked at the optometrist and my eye is healthy. He told me my issues(floaters,pain, after images) are definitely neurological. 1 hour ago, Xcaretuk said: only want to try a very small drop to see if it relieves the pain. It is wise to be cautious. I can only drop 0.5% at the moment without negative effects. It amazes me how the symptoms experienced are so common. 1 20 yr+ Paroxetine/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ August 24-29 2022 10mg Prozac/2022.11.28-2022.12.04- 5mg Paroxetine/Dec 5&6/22 10mg Paroxetine/ Dec 8&9/22 10mg Prozac/ 2022.12.07 to 2023.07.01 5mg Paroxetine TAPER 23.07.02-58mgpw/4.9mgai/ 23.07.21-4.8 mg/23.07.28-4.73 mg/23.08.04-4.65 mg/21.09.23-4.58 mg/27.10.23-4.56 mg/5.12.23-4.54 mg/2.1.24-4.52 mg/9.1.24-4.51 mg/17.1.24-4.49 mg/26.1.24-4.47 mg/6.2.24-4.46 mg/19.2.24-4.44mg /4.4.24-4.43mg/28.4.24-4.4mg/ 8am-probiotics/9am-paroxetine, 200mg mag bisglycinate/ 1000mg Vitamin D/noon-1000 mg algae oil (500mg DHA/10mg EPA/620mg Omega 3)/5pm-75 mg DGL/200mg calcium citrate/8pm-.25 mg melatonin "... your strength will be in keeping calm..."-Isaiah 30:15 I am not a medical professional just your peer. The suggestions I give are based on personal experience and/or the well documented experience of others. Link to comment
Xcaretuk Posted March 30 Author Share Posted March 30 51 minutes ago, LostInCanada said: Yes, this would be the same. Once you stabilize, there is a protocol for slowly transitioning to liquid if you want to. It would be 1/4 of liquid dose with 3/4 pill, then 1/2 and 1/2, then 3/4 and 1/4 and finally all liquid. This would be done over a couple weeks. I was the same and can now do about an hour with my mom or daughter. 10 minutes on the street with a friend, otherwise I am so activated- crying and shaking. So it is slowly getting better after 1.5 years. Paroxetine affects eye sight and can even cause glaucoma. Have you had your eye pressure checked at the optometrist? Be aware to avoid dilation drops as they are anticholinergic. I get similar pressure/pain though not as intense or long lasting. I've been checked at the optometrist and my eye is healthy. He told me my issues(floaters,pain, after images) are definitely neurological. It is wise to be cautious. I can only drop 0.5% at the moment without negative effects. It amazes me how the symptoms experienced are so common. Thanks @LostInCanada you always make me feel a bit better. Yes I had my eyes tested recently and what was interesting since my test last year and something suspicious is that he found a ERM a membrane covering my eye which wasn’t there last year. So I am going back in 6 months. He didn’t seem to be bothered too much but said he would keep an eye on it. It makes you wonder doesn’t it? Is anything anticholinergic something to be avoided ? 1 1998(approx.) 20mg Paroxetine, 1998 -2015 various unsuccessful tapers, 2015 app 6 month taper to 0, 2015 approx 6 months later reinstated original brand after debilitating neurological delayed WD symptoms. Made worse after surgery.2023 Famotidine, Cetirizine, New Generic, muscle relaxer. March/April19th June, 2023 - 23rd July, 2023: Paroxetine Dosage reduced from 20mg to 15mg (on 15mg for 35 days), no significant symptoms. 24th July, 2023 - 26th July, 2023: Paroxetine Dosage reduced from 15mg to 12.5mg (on 12.5mg for 3 days), no significant symptoms. 27th July, 2023 - 3rd September, 2023: Paroxetine Dosage reduced from 12.5mg to 10mg (on 10mg for 39 days), no significant symptoms. 4th September, 2023 - 15th September, 2023: Paroxetine Dosage reduced from 10mg to 5mg i.e. 10mg every other day (on 5mg for 12 days), although not noted, must have experienced some symptoms, as I decided to return to previous 10mg dosage on the 16th September. 16th September, 2023 - 25th November, 2023: Dosage increased from 5mg to 10mg i.e. 10mg every day (on 10mg for 71 days), symptoms start dates: Late September sweating, shaking and right side upper back pain., 5th October 23: Upper back pain worsening,21st Oct 23: Night time symptoms: insomnia, nausea, sweats, headaches, some anxiety (predominantly in the mornings)27th Oct 23 admitted to hospital with 1st hypertensive crisis with severe frontal headache (now suspected of withdrawal ) BP 225/115. Admitted twice more with high BP . Doctors at a loss for cause. Given anti nausea, anti anxiety and sleeping tabs in hospital. . 1st Nov 23: , heart palpitations, some anxiety.. 7th Nov 23: Anxiety was now becoming more frequent (not severe). 26th November, 2023 Dosage increased from 10mg to 20mg possibly first time taking 20 mg of Extine, new manufacturer. 3rd Dec 23 - 18th Dec, 23: Started taking 7.5mg - 15mg of Oxazepam when anxiety became unbearable only took 8 in total now stopped. Symptoms now more severe have head pain rather than headache. .Electrical shocks through body overnight accompanied by head pain. Sheer terror,. Sore eyes. 23rd Dec 23: All symptoms remain the same i.e. severe except for the last 2 days where my anxiety levels have not been as severe/ extreme and somewhat manageable (later in the day).22 Jan 24 Have some windows now but still suffering from all day head pain, upper back pain, waking up inner restlessness and terror , nausea, intermittent feelings of fear and wake up 12.30 am every morning and sometimes up to 3 times a night with weird tingling down arms and back, pounding heart head pain and nausea. 2nd March 24, head pain/eye pain everyday and all day and & night wake ups.. Mild Akathisia early morning,, upper back pain, sweats. Anxiety much better. 21st April 24, drop 2.25% drop to 19.5 mg to test help with head /eye nerve pain and new symptom tinnitus. Link to comment
Administrator Emonda Posted March 30 Administrator Share Posted March 30 33 minutes ago, Xcaretuk said: Thanks @LostInCanada you always make me feel a bit better. Much wisdom flows from LostinCanada 🫡 I know I have asked before, but can you please remind us of the type of scale you are using @LostInCanada for these small cuts? 1 Please don't send me PMs. I am not a doctor. My comments are based on my personal experience with ADs and tapering. Consult your doctor about your own medical decisions. 2017 – 2022: Vortioxetine 15mg, Jan ’22, 15mg->5mg over 4 weeks, Feb ‘22 5mg -> 7.5mg due to WD, July ’22 6.75mg (found SA website), Aug 6.07mg, Sep 5.46mg, 11 Oct 5.00mg, 18 Oct 4.88mg, 25 Oct 4.75mg, 1 Nov 4.63mg, 8 Nov 4.5mg, 3 Jan ’23 4.39mg, 10 Jan 4.28mg, 17 Jan 4.06mg, 13 Feb 3.95mg, 20 Mar 3.85mg, 3 Apr 3.75mg, 10 April 3.65mg, 31 May 3.58mg, 8 June 3.50mg, 15 June 3.43mg, 22 June 3.35mg, 12 Jul 3.29mg, 19 Jul 3.22mg, 26 Jul 3.15mg, 3 Aug 3.09mg, 30 Aug 3.02mg, 7 Sep 2.96mg, 14 Sep 2.89mg, 21 Sep 2.82mg, Oct 11 2.75mg, Oct 19 2.70mg, Oct 26 2.64mg, Nov 2 2.59mg, Nov 23 2.53mg, Nov 30 2.48mg, 7 Dec 2.43mg, 17 Dec 2.38mg, 19 Jan 2.33mg, 26 Jan 2.28mg, 2 Feb 2.24mg, 8 Feb 2.19mg, 29 Feb 2.15mg, 7 Mar 2.10mg, 14 Mar 2.06mg, 21 Mar 1.99mg, 10 Apr 1.95mg, 17 Apr 1.91mg, 24 Apr 1.87mg, Link to comment
LostInCanada Posted March 30 Share Posted March 30 1 hour ago, Xcaretuk said: Is anything anticholinergic something to be avoided ? Since paroxetine is highly anticholinergic, I believe avoiding drugs that do the same is good. Just a few quotes: Anticholinergic medications (shorthand: "anticholinergics") are drugs that block and inhibit the activity of the neurotransmitter acetylcholine (ACh) at both central and peripheral nervous system synapses. Anticholinergic drugs inhibit the parasympathetic nervous system by blocking the action of ACh so that it is unable to bind to receptor sites. They interact with muscarinic cholinergic receptors in the brain, secretory glands, heart, smooth muscle, and eyes. Typical symptoms of anticholinergic medications include dry mouth, constipation, urinary retention, bowel obstruction, dilated pupils, blurred vision, increased heart rate, and decreased sweating 20 yr+ Paroxetine/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ August 24-29 2022 10mg Prozac/2022.11.28-2022.12.04- 5mg Paroxetine/Dec 5&6/22 10mg Paroxetine/ Dec 8&9/22 10mg Prozac/ 2022.12.07 to 2023.07.01 5mg Paroxetine TAPER 23.07.02-58mgpw/4.9mgai/ 23.07.21-4.8 mg/23.07.28-4.73 mg/23.08.04-4.65 mg/21.09.23-4.58 mg/27.10.23-4.56 mg/5.12.23-4.54 mg/2.1.24-4.52 mg/9.1.24-4.51 mg/17.1.24-4.49 mg/26.1.24-4.47 mg/6.2.24-4.46 mg/19.2.24-4.44mg /4.4.24-4.43mg/28.4.24-4.4mg/ 8am-probiotics/9am-paroxetine, 200mg mag bisglycinate/ 1000mg Vitamin D/noon-1000 mg algae oil (500mg DHA/10mg EPA/620mg Omega 3)/5pm-75 mg DGL/200mg calcium citrate/8pm-.25 mg melatonin "... your strength will be in keeping calm..."-Isaiah 30:15 I am not a medical professional just your peer. The suggestions I give are based on personal experience and/or the well documented experience of others. Link to comment
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