Peter23 Posted June 8, 2023 Author Share Posted June 8, 2023 Is 5 years a long time for protracted antidepressant withdrawal to last? 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted June 9, 2023 Author Share Posted June 9, 2023 Had a better day today. Still had the intense anxiety in the morning. Took me several hours to get motivated. Did some work in the garden in the afternoon which made me feel a bit better. Did some relaxation in the evening. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted June 9, 2023 Author Share Posted June 9, 2023 Has anyone on this site experienced protracted antidepressant withdrawal for 5 years or longer? I know from reading the information on here that recovery can be a long process. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Healingcontinues Posted June 10, 2023 Share Posted June 10, 2023 14 hours ago, Peter23 said: Has anyone on this site experienced protracted antidepressant withdrawal for 5 years or longer? I know from reading the information on here that recovery can be a long process. Hi Peter, How are you doing today? 😊 I just had a quick look on the success stories section for you. On the first page there were a few people who seemed to have a longer recovery time around the 5/6 year mark. I will link a few of those below 😊 I can’t seem to find the success story I saw a while back of someone who took longer than that, but I know it’s here somewhere! Its great that you were able to do some gardening yesterday. Even if it didn’t make you feel that much better at the time, doing those things will only help you in the long run! Take care and sending you warm wishes. https://www.survivingantidepressants.org/topic/22069-judith-healing-will-happen/ https://www.survivingantidepressants.org/topic/10596-nadia-5-years-off-i-survived-antidepressants/ https://www.survivingantidepressants.org/topic/22055-coldturkmama-recovered-after-paxil-cold-turkey/ Drug history: zoloft 2015-May 2021 max dose 200mg (3 month fast taper) lexapro 5mg August 2021-September 2021 (adverse reaction, CT) amitriptyline and tempazepam- September 2021 (1 week because of severe insomnia. Did not help. CT) 2018-September 2021 Intermittent use of benzodiazepines (mainly oxazepam, do not know exact dates approx 1-2 per week, although many months without any in between) Link to comment
Moderator Onmyway Posted June 10, 2023 Moderator Share Posted June 10, 2023 @Peter23 You would be counting your withdrawal from the last med change/interventional psych change you made. You started new drugs just last year. Your withdrawal time is the amount of time your brain needs to adjust to yet a new change. Your nervous system needs stability. You are on new drugs and you haven't been cooperating on posting daily symptom diaries for us, as requested, to understand if the agomelatine is hurting you. No one can tell you how long your unique case' is going to last because it is unique in timing/interventions/genetics etc. You need to focus on things you can do to heal - look up non drug emotional management techniques in the symptoms forum. Other ways to help improve your situationmay be helpful as well - engage with other people by offering them support, get out of your head, distract yourself. Omw On 6/8/2023 at 11:50 AM, Peter23 said: Is 5 years a long time for protracted antidepressant withdrawal to last? "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Peter23 Posted June 10, 2023 Author Share Posted June 10, 2023 Thanks Healingcontinues for your kind post and for the links to success stories. I'm feeling better today thanks. Much less anxious and have more energy. Hope you're having a good day and that you continue to recover. Thank again. Best wishes 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted June 10, 2023 Author Share Posted June 10, 2023 Sorry OnMyWay for not posting daily diaries. I have been busy taking care of my partner who has a disability over the past week or so. He has had a flare up of his fibromyalgia. I am feeling better today. Much less anxious maybe due to the magnesium you kindly recommended. As I posted recently I am going to take a CBT course to help me manage my emotions better. I have completed several CBT courses in the past but feel I need to revisit it to remind me of the techniques to use for anxiety management. The main way that the Agomelatine has been adversely affecting me is by increasing my anxiety. I agree with you absolutely that my nervous system needs stability at the moment. It is not my deliberate intention not to cooperate with you. I will endeavour to send daily updates from now on. Thank you for your continued support. It is much appreciated. Best wishes. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted June 10, 2023 Author Share Posted June 10, 2023 Daily Diary: As previously stated my anxiety has not been so overwhelming today. Still have problems with fatigue and lack of motivation. However I have been really pushing myself to become more active today. Did an hours walking today. Also trying to use distraction as much as possible. Keeping in touch with family and friends. Wondering if the daily magnesium is helping with the anxiety along with Vitamins C and B? Trying to use CBT methods to challenge my thinking. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator Onmyway Posted June 10, 2023 Moderator Share Posted June 10, 2023 Hi @Peter23, it may be too late now to do the daily diaries - we wanted them at the time since you were new on the drug and there was an opportunity to discontinue quicker than the 10% IF it was causing you side effects which we would have been able to determine if you had posted a symptom diary with the times of drugs and symptoms as requested and shown in the link. You don't need to apologize to me - these are things that are hurting you, not me. But you need to take responsibility for your recovery. A CBT course would likely help but you need to actually do it. It doesn't help by just thinking about it. Taking care of someone must be difficult and you have my heartfelt compassion but you also need to take care of yourself. You are important too. Take care. https://www.getselfhelp.co.uk/cbt-self-help-course-step-1/ OMW "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Peter23 Posted June 11, 2023 Author Share Posted June 11, 2023 I've only been taking the Agomelatine for 3 months and the symptoms have always been of severe anxiety in the morning. I have sweats rapid heart rate and sweats. I take it at night just before going to bed. If you think it's too late to help me just let me know. I will just have to work with my CPN. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator Onmyway Posted June 12, 2023 Moderator Share Posted June 12, 2023 Hi @Peter23, you are welcome to work with your CPN or whoever you want. Our help is in the information we provide, we can't actually do more than that, you need to implement our advice. So the help is what you take from us. So far you haven't really followed much of the advice we provided and I am not sure that you have read the links I have posted either. Within 1 month of introduction you can stop a drug more quickly if it is giving you adverse reactions (which we didn't manage to establish in your case) - morning anxiety is common with withdrawal as well and I don't know when you take agomelatine. After 1 month being on the drug we suggest that you taper at 10% per month and no faster if you want to taper. Let us know if you do want to taper. I suggest you stabilize on agomelatine first though. OMW "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Peter23 Posted June 15, 2023 Author Share Posted June 15, 2023 Thank you for your reply. I will stabilise on the Agomelatine at the moment. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted June 18, 2023 Author Share Posted June 18, 2023 Just quick question about when I'm ready to taper the Agomelatine. The drug only comes in 25mg and 50 mg tablets and unfortunately is not available in liquid form. What is the best method to use to reduce my dose of 25mg by 10% per month? 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator Onmyway Posted June 18, 2023 Moderator Share Posted June 18, 2023 There is no one best method. Instructions are in the tapering forum on how to measure doses. Links in earlier posts I've made in your thread "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Peter23 Posted June 18, 2023 Author Share Posted June 18, 2023 Thank you. I will look at your earlier thread. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Mezzer Posted July 10, 2023 Share Posted July 10, 2023 @Peter23 hi Peter I’m very interested in l theanine. I’ve noticed you’ve been using it. I also use it and like it but was concerned about affecting my healing coming off psych meds so I’ve been only using it to help when I’m in a severe wave. I would like to start using it regularly to help consistently. I have similar symptoms as you. I’m hoping you’ve had some positive results with it. How much are you taking if you don’t mind me asking. Thank you 1993 started 20mg Prozac. 2008 switched to 10mg of lexapro. 2015 added 50mg of Wellbutrin. Between 2015 and 2020 raised and lowered dosage of both. 2021 moved to Zoloft for one month then back to lexapro for one month. Then switched to 60mg cymbalta for four months. Then Basically cold turkeyed off cymbalta in two weeks using Prozac as a crossover med to reduce withdrawals. Not good. Then had Nortriptylene added to Prozac. Was on 20mg Prozac and 50mg of Nortriptylene for four months. Then did a four month ween off Nortriptylene. To date have been off cymbalta for approximately 11 months and Nortriptylene 7 weeks. Presently taking 12.5 mg Prozac. Also taking 10 mg of bystolic for BLood Pressure. I’m not sure how the Prozac makes me feel. It does nothing to make me feel not sad and anxious at times. I finally figured out the meds are not what I need. What I need is to get off the 12.5mg of Prozac and continue to work on my stuff. Any help is deeply appreciated thank you. Reduced from 12.5 to 10 then from 10 to 7.5. Too much of a drop. Bought a scale and went to 9. Stabilized and went to 8.2 oct 1, 2022. Just got hit with wicked low mood, high anxiety, fatigue, chills. The anxiety is high in the AM and lessons throughout the day. Hoping to stabilize soon Link to comment
Peter23 Posted July 21, 2023 Author Share Posted July 21, 2023 Hi Mezzer I'm taking 1000mg of L Theanine daily. Haven't noticed any improvements in my symptoms so far. Been taking it for about 6 weeks. Best wishes Peter 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Mezzer Posted July 22, 2023 Share Posted July 22, 2023 2 hours ago, Peter23 said: Hi Mezzer I'm taking 1000mg of L Theanine daily. Haven't noticed any improvements in my symptoms so far. Been taking it for about 6 weeks. Best wishes Peter @Peter23 thank you Peter, when I do take it I notice very mild symptom reduction but my symptoms need to be severe to notice. We’re all looking for that magic potion and from what I keep learning time is it. 1993 started 20mg Prozac. 2008 switched to 10mg of lexapro. 2015 added 50mg of Wellbutrin. Between 2015 and 2020 raised and lowered dosage of both. 2021 moved to Zoloft for one month then back to lexapro for one month. Then switched to 60mg cymbalta for four months. Then Basically cold turkeyed off cymbalta in two weeks using Prozac as a crossover med to reduce withdrawals. Not good. Then had Nortriptylene added to Prozac. Was on 20mg Prozac and 50mg of Nortriptylene for four months. Then did a four month ween off Nortriptylene. To date have been off cymbalta for approximately 11 months and Nortriptylene 7 weeks. Presently taking 12.5 mg Prozac. Also taking 10 mg of bystolic for BLood Pressure. I’m not sure how the Prozac makes me feel. It does nothing to make me feel not sad and anxious at times. I finally figured out the meds are not what I need. What I need is to get off the 12.5mg of Prozac and continue to work on my stuff. Any help is deeply appreciated thank you. Reduced from 12.5 to 10 then from 10 to 7.5. Too much of a drop. Bought a scale and went to 9. Stabilized and went to 8.2 oct 1, 2022. Just got hit with wicked low mood, high anxiety, fatigue, chills. The anxiety is high in the AM and lessons throughout the day. Hoping to stabilize soon Link to comment
Peter23 Posted July 24, 2023 Author Share Posted July 24, 2023 Do you think I should start reducing my Agomelatine? I have now stabilised on it for a month. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted July 27, 2023 Author Share Posted July 27, 2023 Have started reducing my Agomelatine gradually today. Using an electronic scale to weigh the tablet and reducing the weight by 5%. Would rather start at a lower dose reduction as I understand from what I have read on this site that it is a very difficult drug to come off. Will fill in a diary tomorrow to document any withdrawal symptoms. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted July 28, 2023 Author Share Posted July 28, 2023 11:55pm: Took Agomelatine 12:30am : ~Asleep 07:30am Woke up with usual morning anxiety: Anxiety score 9(0-10) where 0 is no anxiety and 10 is anxiety could not be worse. 08:00 : Did a 15 minute progressive muscle relaxation. Anxiety score 7 08:00: Had Breakfast 09:00 Washed and dressed. 09:30 Doing housework 12:00 Had lunch. 13:00 Struggling with lack of motivation and fatigue. 14:00 Resting. 15:00 Doing shopping Main symptoms are usual anxiety and lack of motivation. No noticable withdrawal symptoms from small reduction in Agomelatine. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted August 2, 2023 Author Share Posted August 2, 2023 Now tapering agomelatine by 10% of 25mgs. No withdrawal symptoms. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted August 2, 2023 Author Share Posted August 2, 2023 I'm on so many psychotropic drugs, especially since by two extended hospitalizations, that I wonder if I will ever fully recover. I know that the first drug I need to get off is the agomelatine which as I said in my last post I am now tapering by 10% every 4 weeks. However I am very anxious about getting off the zopiclone, diazepam, olanzapine and pregabalin. I know I have to reduce only one drug at a time, but feel a bit discouraged when I think of all the years of drug withdrawals that lie ahead. I am 68 at the moment and dread to think what age I will be when I am finally drug free. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator FireflyFyte Posted August 2, 2023 Moderator Share Posted August 2, 2023 Just now, Peter23 said: I'm on so many psychotropic drugs, especially since by two extended hospitalizations, that I wonder if I will ever fully recover. I know that the first drug I need to get off is the agomelatine which as I said in my last post I am now tapering by 10% every 4 weeks. However I am very anxious about getting off the zopiclone, diazepam, olanzapine and pregabalin. I know I have to reduce only one drug at a time, but feel a bit discouraged when I think of all the years of drug withdrawals that lie ahead. I am 68 at the moment and dread to think what age I will be when I am finally drug free. I have similar concerns as I ended up on three medications (Prozac, Olanzapine, and Gabapentin) after two hospitalizations but I try to remind myself that while it will take years to get off of my current cocktail, I would rather feel decent during those years while I slowly taper versus dealing with horrific withdrawals. Pre- October 2022: Wellbutrin, Escitalopram, Citalopram, Sertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022. Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg Link to comment
Mezzer Posted August 2, 2023 Share Posted August 2, 2023 59 minutes ago, Peter23 said: I'm on so many psychotropic drugs, especially since by two extended hospitalizations, that I wonder if I will ever fully recover. I know that the first drug I need to get off is the agomelatine which as I said in my last post I am now tapering by 10% every 4 weeks. However I am very anxious about getting off the zopiclone, diazepam, olanzapine and pregabalin. I know I have to reduce only one drug at a time, but feel a bit discouraged when I think of all the years of drug withdrawals that lie ahead. I am 68 at the moment and dread to think what age I will be when I am finally drug free. Hang in there my friend. I’m 65 and tapering. Are you stable at the moment. I was CTed off cymbalta two years ago and am tapering one med while still dealing with the crap from the CT. If you are stable go slow and try and enjoy the ride if it’s possible 1993 started 20mg Prozac. 2008 switched to 10mg of lexapro. 2015 added 50mg of Wellbutrin. Between 2015 and 2020 raised and lowered dosage of both. 2021 moved to Zoloft for one month then back to lexapro for one month. Then switched to 60mg cymbalta for four months. Then Basically cold turkeyed off cymbalta in two weeks using Prozac as a crossover med to reduce withdrawals. Not good. Then had Nortriptylene added to Prozac. Was on 20mg Prozac and 50mg of Nortriptylene for four months. Then did a four month ween off Nortriptylene. To date have been off cymbalta for approximately 11 months and Nortriptylene 7 weeks. Presently taking 12.5 mg Prozac. Also taking 10 mg of bystolic for BLood Pressure. I’m not sure how the Prozac makes me feel. It does nothing to make me feel not sad and anxious at times. I finally figured out the meds are not what I need. What I need is to get off the 12.5mg of Prozac and continue to work on my stuff. Any help is deeply appreciated thank you. Reduced from 12.5 to 10 then from 10 to 7.5. Too much of a drop. Bought a scale and went to 9. Stabilized and went to 8.2 oct 1, 2022. Just got hit with wicked low mood, high anxiety, fatigue, chills. The anxiety is high in the AM and lessons throughout the day. Hoping to stabilize soon Link to comment
Peter23 Posted August 3, 2023 Author Share Posted August 3, 2023 Thank you Mezzer for your message of support. I'm experiencing severe depression and anxiety after tapering off Mirtazapine and then Sertraline in 2021. Finding every day a struggle. The agomelatine has made my anxiety worse and done nothing to help with the depression. Hoping that I will feel better once I am off the agomelatine. It helps to know that I am not alone in my struggle. Best wishes Peter 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
prozac2023 Posted August 6, 2023 Share Posted August 6, 2023 Hello Peter, for answer at the question " if is possible to have withdrawall and in the same time have a ssri". Yes its possible. I have that : after 10 years on effexor, i have develloped withdrawall . And tardiv dysphoria. Cannabis 1998, 3 gr par jour 2005_2008 effexor 75mg pour " impulsivité " Mai 2008 arrêt à la dinde froide. Tout va bien, 2 semaines de sevrage. Je vais bien. 09/2009 effexor 75 mg 04/2020 changement de prozac. 25mg 11/2021 30 mg prozac 06/2022 arrêter le cannabis prendre theralène 5 mg deux mois pour dormir 09/2022 arrêter prozac 30 mg , escitalopram 15 mg stop théralène rien pour dormir 11/2022 arrêter l'escitalopram (désir de suicide) et prendre du prozac 30mg prendre un soir du théralène 5mg ou de la mélatonine 2mg ou du xanax 0,5 mg. 11/2022 - 20/01/2023 prozac 30mg 03/03/2023 ct prozac => 150 mg effexor arrêter les médicaments pour dormir. Prenez du cannabis 1 gr pour dormir. 17/09/2023 beginning the réduction in hospital for intolerable side effect. 23/10 /2023 : 0 effexor, 0 cannabis. Link to comment
Peter23 Posted August 7, 2023 Author Share Posted August 7, 2023 Thank you prozac2023 thank you for your message about SSRI withdrawal. Sorry to hear that you're having protracted antidepressant withdrawal that is sometimes referred to as tardive dysphoria. I understand that the term tardive dysphoria has been proposed by a few research papers, but that it is actually persistent antidepressant withdrawal. As I have stated previously my withdrawal symptoms started while I was taking two antidepressants, Mirtazapine and Sertraline in 2018. I stopped both of these in February 2021 and continue to experience withdrawal symptoms just as is the case with you. I hope you feel better soon. Best wishes Peter. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
prozac2023 Posted August 8, 2023 Share Posted August 8, 2023 Hello peter do you have tested sleep apnea ? Because its possible that your depression come from sleep apnea Cannabis 1998, 3 gr par jour 2005_2008 effexor 75mg pour " impulsivité " Mai 2008 arrêt à la dinde froide. Tout va bien, 2 semaines de sevrage. Je vais bien. 09/2009 effexor 75 mg 04/2020 changement de prozac. 25mg 11/2021 30 mg prozac 06/2022 arrêter le cannabis prendre theralène 5 mg deux mois pour dormir 09/2022 arrêter prozac 30 mg , escitalopram 15 mg stop théralène rien pour dormir 11/2022 arrêter l'escitalopram (désir de suicide) et prendre du prozac 30mg prendre un soir du théralène 5mg ou de la mélatonine 2mg ou du xanax 0,5 mg. 11/2022 - 20/01/2023 prozac 30mg 03/03/2023 ct prozac => 150 mg effexor arrêter les médicaments pour dormir. Prenez du cannabis 1 gr pour dormir. 17/09/2023 beginning the réduction in hospital for intolerable side effect. 23/10 /2023 : 0 effexor, 0 cannabis. Link to comment
Moderator Onmyway Posted August 8, 2023 Moderator Share Posted August 8, 2023 8 hours ago, Peter23 said: Thank you prozac2023 thank you for your message about SSRI withdrawal. Sorry to hear that you're having protracted antidepressant withdrawal that is sometimes referred to as tardive dysphoria. I understand that the term tardive dysphoria has been proposed by a few research papers, but that it is actually persistent antidepressant withdrawal. As I have stated previously my withdrawal symptoms started while I was taking two antidepressants, Mirtazapine and Sertraline in 2018. I stopped both of these in February 2021 and continue to experience withdrawal symptoms just as is the case with you. I hope you feel better soon. Best wishes Peter. @Peter23 Tardive dysphoria and withdrawal are not the same thing. Tardive dysphoria means basically 'delayed feeling bad' it can be delayed from anything including a traumatic event. It is doctors' way of avoiding the term withdrawal. Withdrawal is much more complex, it is much more than bad mood. It impacts people's sleep, immune system, GI system, nervous system. For many it is physically debilitating. It goes for years and has periods of respite called windows and then symptoms come back and improves slowly over time. Delayed bad mood can happen to people and is often part of the equation but is a very small part of it. Calling withdrawal 'tardive dysphiria' is like calling brain cancer a headache. "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Peter23 Posted August 8, 2023 Author Share Posted August 8, 2023 Hi prozac 2023 I don't suffer from sleep apnea. My symptoms are caused by protracted antidepressant withdrawal. Best wishes Peter 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted August 27, 2023 Author Share Posted August 27, 2023 I'm terrified by the prospect of coming off all the medications I have been on long term namely: Olanzapine 7.5mg: Pregabalin 600mg: Diazepam 10mg and Zopiclone 7.5mg. I am due to see a new psychiatrist and am really concerned that she might want me to come off one or more of these drugs while I'm in the process of tapering Agomelatine. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted August 27, 2023 Author Share Posted August 27, 2023 Apologies for my last post. I have now written a summary of my misdiagnosis and how I ended up on so many drugs as a consequence, for my psychiatrist. I have also included that I have come to the conclusion that I am suffering from protracted antidepressant withdrawal through my contact with this website. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator FireflyFyte Posted August 29, 2023 Moderator Share Posted August 29, 2023 On 8/27/2023 at 7:35 PM, Peter23 said: Apologies for my last post. I have now written a summary of my misdiagnosis and how I ended up on so many drugs as a consequence, for my psychiatrist. I have also included that I have come to the conclusion that I am suffering from protracted antidepressant withdrawal through my contact with this website. Hi Peter, No need to apologize. It can be nerve wracking trying to talk with doctors who don't understand safe tapering and withdrawals. Have you read How to talk to a doctor about tapering and withdrawal? What to expect.? Thanks, Firefly Pre- October 2022: Wellbutrin, Escitalopram, Citalopram, Sertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2024 = 0.7mg -> Apr 28, 2024 = 0.66mg Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022. Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg Link to comment
Peter23 Posted September 1, 2023 Author Share Posted September 1, 2023 Thanks Firefly I have read How to talk to a doctor about tapering and withdrawal. I know it will be difficult to convince my psychiatrist that I am suffering from protracted depression withdrawal. Best wishes Peter 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted September 4, 2023 Author Share Posted September 4, 2023 My mental state is getting much worse. Currently reducing Agomelatine by 10% every 4 weeks. Having increased anxiety and panic and my depression is much worse. Struggling with the activities of daily living. Deeply regret starting the Agomelatine when I was hospitalized. Was'nt thinking straight when I agreed to start it. Been using the Dr Claire Weekes method to try to control my anxiety with limited effect. Think the Agomelatine is going to be harder than I thought to taper off. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
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