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hallbag: Itchiness on Sertraline - Side effect?


hallbag

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Hey everybody, I’m a new member, so please let me know if this is not okay or goes against anything. 
 

I will keep it as short and sweet as I can. 
 

Many years ago, I was put on Sertraline. I was quite young and I can’t remember anything negative about it. 
 

In December last year, I was put on 50mg of Sertraline (28th), and I tapered off 25mg of Notripyline and stopped completely the day prior (27th). I was on the Sertraline for 2 weeks, and 4 days when the itchiness started. It feels like a light tickle, or as if something has brushed against my skin, like a hair. It can be anywhere on my body. Once I scratch it, it stops, and then will move elsewhere. I’m not frantically scratching, it’s not keeping me awake and I’m not damaging skin, but it makes me anxious, agitated and restless. I will often bounce my leg or do something. The itching stopped for a few days (27th Jan until 31st) and then returned. I did develop a rash on my stomach on the 27th, which was itchy and red. I’m unsure what caused this, but it was near my injection site where I inject Ajovy (a headache/migraine medication). I injected that on the 21st of Jan, rash appeared 27th. I don’t think it’s related to my itchiness, it happened to settle when I first had the rash. The rash is no longer itchy and is fading with hydrocortisone cream. 
 

I am also on 25mg of Quetiapine, which was increased to 50mg on the 27th of December last year to assist with any insomnia that weaning of the Notripyline may cause. 


I guess what I want to know, is this a side effect of Sertraline/SSRIs? I’m very worried I’m developed some sort of compulsion or health condition. I’ve read in a lot of places that itchiness can be a side effect due to the serotonin increase. 
 

I also smoke marijuana. I’ve never had any other drug reactions. 
 

Thank you in advance 

Edited by Emonda
Name to title

- Notriptyline (increase) 25mg to 50mg 28-11-23

- Started Ajovy 21-12-23

- Stopped Nortriptyline 27-12-23

Increased Quetiapine from 25mg to 50mg 27-12-23

- Started 50mg of Zoloft 28-12-23

- Itching started 15-01-24 (2 weeks, 4 days from starting Zoloft)

- Increased Zoloft to 100mg 19-01-24

- Injected Ajovy 21-01-24

- Rash on stomach 27-01-24, itchiness less noticeable until 31-01-24

- Itching sensation still 06-02-24

- Decreased Zoloft from 100mg to 75mg 07-02-24

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  • Emonda changed the title to hallbag: Itchiness on Sertraline - Side effect?
  • Moderator

Hi hallbag,

 

Welcome to SA. Please summarize your drug history in your signature by following the instructions at How to Summarize Your Drug History in Your Signature. You may need to be on a computer to complete this.

Once your signature is in place, we can assist further.

 

Thanks,

 

Firefly

 

Pre- October 2022: Wellbutrin, Escitalopram, CitalopramSertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda

Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg -> Jan 22, 2024 = 0.97mg -> Feb 4, 2024 = 0.92mg -> Feb 19, 2024 = 0.87mg -> Mar 3, 2024 = 0.83mg -> Mar 17, 2024 = 0.78mg -> Mar 31, 2024 = 0.74mg -> Apr 14, 2023 = 0.7mg

Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022.

Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg -> Dec 9, 2023 = 436mg -> Dec 24, 2023 = 414mg -> Jan 7, 2024 = 400mg

 

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  • 4 weeks later...

Just wanted to mention I have a rash on this drug too, started about 3-4 weeks after I began sertraline.

2013/14(?) - March 2022 paroxetine 20 mg
3rd March 2022 - escitalopram 10 mg

9th June 2022 - escitalopram 20mg
15th December 2022 - venlafaxine xr 37.5

Mid November - advised switch to SSRI

23rd December 2023 - sertraline 50mg 

25th January 2024 - 75mg EOD

26th Feb 2024 to 3rd March 2024 drug holiday due to allergic reaction

3rd March 2024 - Resume sertraline 50mg

5th March started 10% sertraline taper 45mg

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