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BfromNJ: mirtazapine taper


BfromNJ

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I didn't post my log yesterday, but previously have been daily.  Yesterday was mild as far as my one troublesome symptom, the genital/urinary issues.   And looking back on my logs, they seem to settle some later in the day/evening hours.    the internal tremors and pulsing was still there yesterday and is persistant throughout the day.     I was looking at my logs to see if I can find a connection to the symptoms and the timing of my meds.  I know that ADs are known to cause pgad (not sure if this is my problem yet), so I am wondering if when I lowered the gabapentin, it increased the side effects of the luvox?  Or is it possible I am having interdose withdraw with the luvox?  Is this possible?   This is why I entertained moving the luvox up to taking it in the morning, instead of at 12:30 pm.  Originally I was taking it at 12:30 to keep it away timing wise from my Seroquel.  I just thought if I took it first thing in the am, it would maybe help for now through out the day. Or, if it is the luvox causing this since I lowered the gabapentin, do I maybe focus my taper on the luvox again instead of the gabapentin? 

 

 

my other thought was that maybe the symptoms are from the gabapentin and as it wears off they abate some during the day and this taper should continue.  This could very well be?

 

 

I know no one on here can make my decision what to taper or do, and only offer advice.  But I was just wondering if this makes any sense? I really hate this polydrugging.  I know should not switch back and forth to what I am reducing, but I want to at least make sure I am heading in the right direction.   and at least I am reducing my drug load in general.   To date, I have done a 25% drop in my luvox on 4/6 and an 8% drop in my gabapentin.  Orginally the luvox was started because it was supposed to be the activating one.  But luvox from what I understand isn't an activating one, since its for OCD.  I think I am more so on three brakes between the luvox, Seroquel and gabapentin.  

 

I know I am stretching here as to what my symptoms are caused by, with being on three meds.  I just want to make sure my next reduction is the right one.  Which I guess is just a crap shoot anyway? 

 

 

Can someone point me maybe in the right direction to find out more information on how reducing one med may impact the metabolism of another? 

 

 I know the general rule of thumb here is to focus on one mediation at a time, but is it sometimes okay to reduce one a bit, hold and then reduce another some?

 

 

 

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

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forgot to also add - could the 25% drop I did with the luvox now be causing this genital (pgad?) type of issue almost 4 months out? i know it can also happen in withdraw. 

 

It seems like this came on coincidentally after my gabapentin reduction.   So i was wondering if this reduction has somehow affected the luvox.  

 

Edited by ChessieCat
removed quote

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

Link to comment

another thought regarding the above,  do i tend to feel better later in the day/evening because the seroquel has left me system some?   i know im searching for an answer that may not be there, but i'd appreciate any input anyone has .   So my  thoughts/ponderings are three fold i guess:

 

Is the luvox having a beneficial effect after taking it as far as my physcial symptoms or maybe i am having withdrawal inbetween my dose?  

 

did the gabapentin reduction increase side effects of the other?  

 

is there seroquel leaving my system at the time of reduced symptoms?

 

 I was just wondering if any of this should impact my next reduction.  

 

I value everyones experience and knowledge.  

 

 

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

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  • Moderator Emeritus

Interaction check for gabapentin, luvox and seroquel on https://reference.medscape.com/drug-interactionchecker

 

Monitor Closely

  • fluvoxamine + quetiapine

    fluvoxamine will increase the level or effect of quetiapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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  • Moderator Emeritus

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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1 hour ago, ChessieCat said:

Interaction check for gabapentin, luvox and seroquel on https://reference.medscape.com/drug-interactionchecker

 

Monitor Closely

  • fluvoxamine + quetiapine

    fluvoxamine will increase the level or effect of quetiapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

Yes I've seen this.    All of my drugs interact, with luvox and seroquel being the worst.  That being said,  do I continue to reduce the luvox?  Or will that cause a paradoxil effect with the seroquel. The seroquel is for sleep, I'd be a bit nervous to lower that right now.    Alto had said to consider it, but I held at that point bc I was settling still from gabapentin reduction. 

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

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  • Moderator Emeritus

I did the interaction because you were questioning:

 

3 hours ago, BfromNJ said:

 

did the gabapentin reduction increase side effects of the other?  

 

 

Because of the situational stressors as well as being on an antibiotic for a possible infection, it is making it difficult to know what is causing what.  When that happens the usual suggestion is to keep all things the same so that you can establish a baseline.  It is going to take some time to try and work out what is going on and what is the next step.

 

And that is why the daily symptom notes are so important.

 

11 hours ago, BfromNJ said:

didn't post my log yesterday

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

Link to comment
  • Moderator Emeritus

Hi BfromNJ,

Yes, go to the interaction checker again, and if you'd like you could opt for the professional information.

And then more on the CYP metabolism here: 

So yes, shifts in drugs that utilize the same enzyme for metabolism do cause some drug interactions.  Your Luvox and Seroquel. 

Let's try and keep discussion around your meds., right here, in your introduction, for now too.  Rather than take them to Journals and Scientific Sources section.  And,  as you look through that thread you'll find more and more, to help your understanding.  There are links and further explanations there.  I mean it does help to gain an understanding, I think. 

Yikes though, it took me awhile.  It's complicated.  So.....don't get too frustrated or jump to panic either.

 

Simply put though, yes, when you make a switch with your Luvox or Seroquel, or dose change, it may effect the other medication metabolism, as well.

The gabapentin, not so much. 

And you've got your Luvox and Seroquel spaced from each other too.  That's good.

 

I'm still leaning toward that you keep going with the gabapentin taper, singularly, just that.  And as you continue to do and post your notes, you/we can get a better feel for, if that is the medication, that now is causing you the most difficulty, in the way of adverse effects. 

 

So, yes.......keep going now with the daily notes.  Get the time to the left.  And then all your drugs and doses to the right.  Along with brief symptom descriptions on the right, you can rate with a scale of 1-10.  Note your sleep.  Depression.  Anxiety.

Situational stuff and adjusting to feelings and changes can go in a separate narrative post.

That might make it most clear for moderators and administration.

 

Taking multiple psych drugs? Which drug to taper first?

Your Luvox is an SSRI.  Therefore, more of an accelerator.  And yes, usually would be the first to go. 

If most of your adverse effects ARE gabapentin related, it does make sense to just stick with the gabapentin taper when your tapering resumes. 

 

You get into multiple medication tapers and it can just get too complicated, to know what is what. 

So, I really think it would be best to continue to go with gabapentin.  Pending, of course, if anything, stands out in your notes, otherwise.

 

 

7 hours ago, BfromNJ said:

another thought regarding the above,  do i tend to feel better later in the day/evening because the seroquel has left me system some?   i know im searching for an answer that may not be there, but i'd appreciate any input anyone has .   So my  thoughts/ponderings are three fold i guess:

 

Is the luvox having a beneficial effect after taking it as far as my physcial symptoms or maybe i am having withdrawal inbetween my dose?  

 

did the gabapentin reduction increase side effects of the other?  

 

is there seroquel leaving my system at the time of reduced symptoms?

 

 I was just wondering if any of this should impact my next reduction.  

 

Tough questions to answer definitively BfromNJ.

Maybe........just a little.   I know Seroquel sure gave me the blahs, even at 25 mg.  And I was on much larger doses too.  Man, sometimes I'd feel better in the evening just because I'd made it through another day.

I mean you've still got a lot of other WD going on, from previous drugs too.  And then these new drugs.  BfromNJ,  I had to go through the same.  Just take it slow and steady.  You'll get there.  You've had a heck of a year. 

When we take medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made.  The CNS likes stability.

Maybe you are getting a beneficial effect from the Luvox.  It's got a shorter half life, than most of the SSRI's, but I don't think you need worry about interdose WD now.

No, on the gabapentin reduction increasing s.e.'s of the others.  At least I don't think so.  As I said above, with the CYP stuff. 

 

It's tough, it is, to sort out, and I'm not sure what symptoms you are referring to.

 

So.....maybe that helps. 

Notes.  HOLD.  And just keep on doing your best to keep your spirits up.  Hone up on some non-drug coping skills too.  You'll  thank yourself later.  I know it feels like forever and a day, for a change.  The alternative though, of too many changes, too fast, is just not good though.  Been there, done that myself.  And I don't want you to go through that again.

 

Okay, and best,

L, P, H, and G,

mmt

 

Edited by manymoretodays

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

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10 hours ago, ChessieCat said:

I did the interaction because you were questioning:

 

 

Because of the situational stressors as well as being on an antibiotic for a possible infection, it is making it difficult to know what is causing what.  When that happens the usual suggestion is to keep all things the same so that you can establish a baseline.  It is going to take some time to try and work out what is going on and what is the next step.

 

And that is why the daily symptom notes are so important.

 

Thanks Chessie.  I understand.  its just frustrating because these physical symptoms are really debilitating and have such an impact on my mental well being.   thank you. yes, im holding right now.

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

Link to comment

Thank you so much for your response.   I see now about it not being the gabapentin causing additional side effects, as its not involved in the CYP .   that would be the luvox affecting the Seroquel.  When I look at the interaction checker between the two, the luvox increases the side effects of the Seroquel the most.    I am an ultrarapid metabolizer on the cyp (had my genentic testing).  Not sure if that's a good thing or a bad thing as far as the luvox and Seroquel go.  maybe the 25% drop in April in the luvox is catching up with me.   Would an updose help or should I just hold it? 

 

The symptoms I was referring to are the internal tremors/pulsing/vibrating feeling I get every day in my left food, leg, groin, abdomen, chest and torso.  And the frequent/urgent urination (severe) and genital sensitivity and arousal type feeling there.   these are all a daily thing . 

 

and I see what you mean about previous withdraw.  

 

And im a holdin.  lol.   on.  by a thread.  :) 

 

Edited by ChessieCat
removed quote

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

Link to comment
7/29 daily symptom/drug log:
 
5:45- up.  bad night sleep.  
- 183 mg gabapentin.
- genital symptoms start up
10:20- decrease in genital/urinary symptoms
12:00- genital symptoms increase again
12:30- 183 mg gabapentin and 18.75 mg luvox 
2:00- feeling severely depressed and hopeless over physical symptoms.  very down.
- fatigue 
3:00- genital symptoms settle some. 
4:30- gym
5:30- slight increase in genital symptoms. 
8:30- 183 mg gabapentin
6:30-9:00- lessened genital symptoms 
9:30- genital symptoms bad again. 
9:45 - 25 mg seroquel
10:00- bed
 
main daily symptoms
-internal tremor/pulsing persistant in left foot, leg. groin , abdomen,  torso.this symptom is pretty much all day, after about an hour awake
-severe frequent urination through out whole day
-genital sensitivity/arousal feelings and discomfort

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

Link to comment
2 hours ago, BfromNJ said:

Maybe you are getting a beneficial effect from the Luvox.

I was initially thinking it may be helping with the symptoms, but I noticed in my logs that a few hours after I take it, I get very down and hopeless. not sure if this is just a coincidence, or hormone timing or my gabapentin drug load, since I take it at the same time, but something to watch out for .  

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

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  • Moderator Emeritus
2 hours ago, BfromNJ said:

Not sure if that's a good thing or a bad thing as far as the luvox and Seroquel go.  maybe the 25% drop in April in the luvox is catching up with me.   Would an updose help or should I just hold it? 

 

Just HOLD the Luvox.  Your Luvox and gabapentin actually do have some interactions, just not the CYP metabolism conflicts.  Some increase in side effects:

 

Interactions between your drugs

Moderate

gabapentin fluvoxaMINE

Applies to: gabapentin, Luvox (fluvoxamine)

Using gabapentin together with fluvoxaMINE may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

 

I sure can't see any benefit to you doing frequent changes of different medications.  If I were you, I think I'd stick with tapering the gabapentin further.  I'm not a huge fan of gabapentin.  And then........address the Luvox.  Leaving the Seroquel for last.

 

Non-drug coping.  See previous suggests for calming some of the internal tremor.

 

And I saw that you have been dealing with a lot of ruminating, obsessive type thinking.  Those looping around, over and over type thoughts.

 

Here is something that might help:

Dealing With Emotional Spirals

Techniques, to modify the experience of the ruminating thoughts.

And a bit more in this topic on Obsessive compulsive disorder: Repetitive intrusive thoughts......

 

And you've got to work this stuff B.  Daily.  While you begin to Live your life a bit again.  I mean if you are invested in tapering and then eventually getting drug free.

Are you working now, or thinking of getting back to something.  Getting out with one person or others?  Getting into nature and sunshine?  Distraction can do wonders too.  Getting around the site and finding some positives to adopt?  Or offering support sometimes does wonders too.  Here or on the ground(in your area).

 

Yah, Luvox is not the greatest drug.  None of them are.  Good to get to know your patterns, each day though.  How can you best deal with the down periods now?

 

Beautiful day, here in Paradise, 

What are your plans today? 

Best,

L, P, H, and growth,

mmt

 

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

Link to comment

The internal tremor seems to be a physical thing, not anxiety related.  i think its side effect.  

 

This is all good information, thank you.  im gonna read through it.   I am working.  Although soon to be unemployed as i am making my move south .  yikes.  hope to find employment quickly down there.   maybe change is good though this time.  although scary.  I will be near my parents and my brother.  all very supportive.   Just gonna be hard leaving my daughter, who is 21.  but she is super busy, college, work, boyfriend so i dont see her much anyway.  lol.  

 

Edited by ChessieCat
removed quote

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

Link to comment
  • Mentor

BfromNJ,

 

Gabapentin is one *obnoxious* drug to taper. [I'd like to follow this by a few of my favorite swear words, but out of respect for the rules, I will refrain.] Sorry you are going through it. It can cause some really weird symptoms. I've had the burning, genital sensations (thankfully not quite as bad as you), difficulty seeing, muscle twitches, myoclonus, rib muscle twitch, severe hotflashes, cold sweats, involuntary facial movements, chorea movements of trunk and arms (that was a very scary and very public symptom), tics, tremors, severe mood swings, dr/dp, suicidal thoughts, I suspect some delirium in there, and on and on and on. A lot of that has calmed way down now that I'm taking it slowly. I have my psychiatrist to thank for that fun ride. In my opinion, gabapentin is like one of the best drugs out there to get oneself the heck off of!!! As in, it is not a good drug to be on.

 

In terms of your fear of tremors being permanent I suppose anything is possible, but think logically about it: if the tremors started during withdrawal, they're a withdrawal, not drug itself, symptom. I really suffered with that fear, but I've found that when I stabilized, these symptoms improved greatly and some of the worse ones have gone away (like the chorea). I think going too fast has a bigger potential to cause long term problems than staying on. I have some permanent wrist cogwheeling that came up after tapering an ssri too fast years ago.

 

After a certain point, wondering what's causing what stops being productive and can drive you crazy. That kind of perseveration itself may be a sign of withdrawal. I know I go through that. It's very disturbing when we realize what these drugs have been doing and can do to us, and it's it's own kind of mental torture to have to remain on the drugs tapering for our own safety, while being aware of all of this.

 

I think once you've been at the gabapentin taper for awhile, you'll get familiar with the symptoms and you'll feel more confident. That is what has been happening for me. Right now you don't have enough familiarity with the symptom pattern. But after you stabilize and drop again, you'll get more info about whether or not your current symptoms are caused by the gabapentin taper.

 

Hang in there. Once you've completed the gabapentin taper, everything else may feel like a walk in the park in comparison. Pat yourself on the back--it takes some serious persistence and resilience to taper gabapentin.

Now: 100 mg Zoloft am, 50 mg Trazodone.  Daily drug burden decreased from 2050 in 2018 mg to 150 mg 🐢🐢

Zoloft: 1/24/23 increased to 100 mg after suicide attempt 9/17/22 cut 6 mg, 8/14/22 cut 6.5 mg, 5/7/22 cut 12.5 mg 3/20/22 cut 12.5 mg 10/26/21 cut 6 mg 10/17/21 cut 5 mg, 9/17/21 Cut 3 mg,  9/13/21 cut 4 mg, 8/29/21 Cut 2 mg 8/8/21 Cut 3 mg  7/30/21 Zoloft: Converted 25 mg to liquid. Also take 100 mg pill & 25 mg pill=150 mg total
🌞 Feb 28, 2021 0 mg Gapapentin 2021 Gaba each dose 4x/day: Feb 27 7 mg (one dose only), Feb 10, 7 mg, Jan 14 10 mg 2020 Current taper schedule from Aug 30-present: drop 8 mg every 2-3 weeks. Aug 20 31 mg, Aug 18, 33 mg, July 29, 35 mg, July 23 38 mg, July 22 40 mg Jun 24 42 mg, Jun 15 44 mg, Jun 9 48 mg, May 22 50 mg, May 14 54 mg, May 7 56 mg, Apr 16 58 mg, Mar 28 60 mg, Mar 18 62 mg. Feb 26 64 mg. Feb 19, 66 mg. Jan 23, 70 mg. 2019 Dec 19, 72 mg. Nov 14 ,76 mg. Aug 8, 80 mg. Aug 6, 85 mg. Jul 26, 90 mg. Jul 11, 95 mg.

Jul 16 trazodone from 100 to 50 mg.

Jun 17-July 10 Slowly changed gab fr pill to liquid at same dose 100 mg 4x/d.

Apr 24 Stopped klon!!! 🌞 Apr 4  Decreased gaba to 400 mg (100 mg 4x/day)-Apr 4, 2019   0.25 klon March 11  Klonopin .5 mg twice daily, varied dose til Apr 15. Started Klon fast taper 25%, short use

Mar 16, 450 mg gaba 3x/day cut 600 mg--not exact!--updose after learning w/d

Feb 20, 2019 1800 mg gabapentin; MD taper; off 3 days=mvt disorder & autonomic instability. July 2018 temazepam 15 mg 1-2; prn several x/wk til Jan/Feb 2019 when cold turkey, flu illness for months

July 2018 started gabapentin 100 3x/day; titrated up to 1800 mg (600 3x/day)

Buspar, I forget how much, 2 pills a day Jan 2017-July 2018 cold turkey. On Zoloft since maybe 2004? After trying many.

*I speak from my experience. Nothing I say is medical advice. I'm not a doctor.

Link to comment
7/30 daily log
 
4:00- up.  unable to fall back asleep.  
-urinary urgency/frequency-persisted through morning (10/10- constant)
5:45- 183 mg gabapentin
6:45- breakfast
-genital symptoms -persisted thru morning but much lower 
- internal tremor/pulsing/vibration in left foot leg, genitals, torso, abdomen and chest (lower today)
10:00- genital symptoms die down and tremor 
12:00- fatigue and low mood 
12:30-183 mg gabapentin and 18.75 mg luvox
1:45- genital symptoms increase again and tremor/pulsing in foot, leg and groin - very uncomfortable. 
3:30- genital symptoms lesson - almost gone 
6:00- dinner 
8:30- 183 mg gabapentin
9:45- 25 mg seroquel
 
symptoms lessened alot during evening.   still terrible frequent urination.   
 
- symptoms not bothersome for the evening
- did have internal tremors/pulsing  when going to sleep.
-still frequent urination 
 
 

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

Link to comment

Hi ShiningLight.  thank you for your post.  It just helps me to reinforce that i need to continue onward with this taper of this particular drug.  My first drop was 10% on 6/5 and i've had to hold there. which i hate because its such a lengthy process.  but with the symptoms i have had, i ididnt want to rock the boat.   I may even do a brass monkey slide the next drop.  I want to drop again, but right now i have some life changes, so i best wait a bit more.  But these last few days i have been feeling better.  Knock on wood! lol.  because it seems like when i say that, something else crops up!  

 

I have been following you and i see you seem to be doing better, which is great!   Especially after that big trazadone drop.   

 

Thanks again for reaching out and i hope  you have a great day. 


 

Edited by ChessieCat
removed quote

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

Link to comment
  • Mentor

Good for you for holding! You're not alone--I found that 10% in one drop was too much for me with gabapentin. When I held for as long as you've been holding, I was in a confident place for my next drop. So you really will reap the rewards! Glad you're starting to feel better. That is also the nature of the gabapentin taper...you start feeling better, then wham! 🙄

 

I got lucky with the trazodone. I don't recommend trying that. It did end up helping my muscle tension a lot though. I still have it, but it's tolerable now.

Now: 100 mg Zoloft am, 50 mg Trazodone.  Daily drug burden decreased from 2050 in 2018 mg to 150 mg 🐢🐢

Zoloft: 1/24/23 increased to 100 mg after suicide attempt 9/17/22 cut 6 mg, 8/14/22 cut 6.5 mg, 5/7/22 cut 12.5 mg 3/20/22 cut 12.5 mg 10/26/21 cut 6 mg 10/17/21 cut 5 mg, 9/17/21 Cut 3 mg,  9/13/21 cut 4 mg, 8/29/21 Cut 2 mg 8/8/21 Cut 3 mg  7/30/21 Zoloft: Converted 25 mg to liquid. Also take 100 mg pill & 25 mg pill=150 mg total
🌞 Feb 28, 2021 0 mg Gapapentin 2021 Gaba each dose 4x/day: Feb 27 7 mg (one dose only), Feb 10, 7 mg, Jan 14 10 mg 2020 Current taper schedule from Aug 30-present: drop 8 mg every 2-3 weeks. Aug 20 31 mg, Aug 18, 33 mg, July 29, 35 mg, July 23 38 mg, July 22 40 mg Jun 24 42 mg, Jun 15 44 mg, Jun 9 48 mg, May 22 50 mg, May 14 54 mg, May 7 56 mg, Apr 16 58 mg, Mar 28 60 mg, Mar 18 62 mg. Feb 26 64 mg. Feb 19, 66 mg. Jan 23, 70 mg. 2019 Dec 19, 72 mg. Nov 14 ,76 mg. Aug 8, 80 mg. Aug 6, 85 mg. Jul 26, 90 mg. Jul 11, 95 mg.

Jul 16 trazodone from 100 to 50 mg.

Jun 17-July 10 Slowly changed gab fr pill to liquid at same dose 100 mg 4x/d.

Apr 24 Stopped klon!!! 🌞 Apr 4  Decreased gaba to 400 mg (100 mg 4x/day)-Apr 4, 2019   0.25 klon March 11  Klonopin .5 mg twice daily, varied dose til Apr 15. Started Klon fast taper 25%, short use

Mar 16, 450 mg gaba 3x/day cut 600 mg--not exact!--updose after learning w/d

Feb 20, 2019 1800 mg gabapentin; MD taper; off 3 days=mvt disorder & autonomic instability. July 2018 temazepam 15 mg 1-2; prn several x/wk til Jan/Feb 2019 when cold turkey, flu illness for months

July 2018 started gabapentin 100 3x/day; titrated up to 1800 mg (600 3x/day)

Buspar, I forget how much, 2 pills a day Jan 2017-July 2018 cold turkey. On Zoloft since maybe 2004? After trying many.

*I speak from my experience. Nothing I say is medical advice. I'm not a doctor.

Link to comment
9 hours ago, ShiningLight said:

Good for you for holding! You're not alone--I found that 10% in one drop was too much for me with gabapentin. When I held for as long as you've been holding, I was in a confident place for my next drop. So you really will reap the rewards! Glad you're starting to feel better. That is also the nature of the gabapentin taper...you start feeling better, then wham! 🙄

 

I got lucky with the trazodone. I don't recommend trying that. It did end up helping my muscle tension a lot though. I still have it, but it's tolerable now.

So are you tapering less than 10%?  I was thinking of doing 5 next.  

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

Link to comment
  • Mentor

Yes I am. It feels good when you see that you can decrease your reaction by slowing down!

Now: 100 mg Zoloft am, 50 mg Trazodone.  Daily drug burden decreased from 2050 in 2018 mg to 150 mg 🐢🐢

Zoloft: 1/24/23 increased to 100 mg after suicide attempt 9/17/22 cut 6 mg, 8/14/22 cut 6.5 mg, 5/7/22 cut 12.5 mg 3/20/22 cut 12.5 mg 10/26/21 cut 6 mg 10/17/21 cut 5 mg, 9/17/21 Cut 3 mg,  9/13/21 cut 4 mg, 8/29/21 Cut 2 mg 8/8/21 Cut 3 mg  7/30/21 Zoloft: Converted 25 mg to liquid. Also take 100 mg pill & 25 mg pill=150 mg total
🌞 Feb 28, 2021 0 mg Gapapentin 2021 Gaba each dose 4x/day: Feb 27 7 mg (one dose only), Feb 10, 7 mg, Jan 14 10 mg 2020 Current taper schedule from Aug 30-present: drop 8 mg every 2-3 weeks. Aug 20 31 mg, Aug 18, 33 mg, July 29, 35 mg, July 23 38 mg, July 22 40 mg Jun 24 42 mg, Jun 15 44 mg, Jun 9 48 mg, May 22 50 mg, May 14 54 mg, May 7 56 mg, Apr 16 58 mg, Mar 28 60 mg, Mar 18 62 mg. Feb 26 64 mg. Feb 19, 66 mg. Jan 23, 70 mg. 2019 Dec 19, 72 mg. Nov 14 ,76 mg. Aug 8, 80 mg. Aug 6, 85 mg. Jul 26, 90 mg. Jul 11, 95 mg.

Jul 16 trazodone from 100 to 50 mg.

Jun 17-July 10 Slowly changed gab fr pill to liquid at same dose 100 mg 4x/d.

Apr 24 Stopped klon!!! 🌞 Apr 4  Decreased gaba to 400 mg (100 mg 4x/day)-Apr 4, 2019   0.25 klon March 11  Klonopin .5 mg twice daily, varied dose til Apr 15. Started Klon fast taper 25%, short use

Mar 16, 450 mg gaba 3x/day cut 600 mg--not exact!--updose after learning w/d

Feb 20, 2019 1800 mg gabapentin; MD taper; off 3 days=mvt disorder & autonomic instability. July 2018 temazepam 15 mg 1-2; prn several x/wk til Jan/Feb 2019 when cold turkey, flu illness for months

July 2018 started gabapentin 100 3x/day; titrated up to 1800 mg (600 3x/day)

Buspar, I forget how much, 2 pills a day Jan 2017-July 2018 cold turkey. On Zoloft since maybe 2004? After trying many.

*I speak from my experience. Nothing I say is medical advice. I'm not a doctor.

Link to comment
8/1 daily log
 
5:15- up
5:30- 183 mg gabapentin and probiotic
-feeling overall pretty good. 
7:30- slight genital symptoms - sensitivity. arousal
-internal tremor/pulsing/vibrating in feet, legs, groin
11:30- internal tremor/pulsing/vibrating in chest, left foot, groin
-genital symptoms
12:30-183 gabapentin and 18.75 mg luvox
-fatigue
-slight genital symptoms but very mild, almost not noticable 
6:00-dinner
8:30- 183 mg gabapentin
9:30- 25 mg seroquel
 
-genital symptoms greatly improved today .  almost none.
- still frequent urination but not as bad.  
 
I have been feeling alot better the last couple of days.  much more stable. I think i have gotten back to withdrawal normal.  Maybe even better.  That or i am in a window.  Either way, i will take it!

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

Link to comment
8/2 daily log
 
5:30-183 mg gabapentin
probiotic
12:30- 183 mg gabapentin and 18.75 mg luvox
8:30- 183 mg gabapen5:45tin 
9:30- 25 mg seroquel
 
 -frequent urination, but not as bothersome
 
- tinnitus amped up, shortly after awakening .  persistant thru day. very bad in the evening.
 
-5:00 pm -  no genital symptoms until after using elliptical at gym.   along with internal tremor/pulsing in foot leg, groin .  seemed to aggravate it.
 
- second day of feeling good, beside above set back.  
 
- no anxiety.  calm mood.

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

Link to comment
  • Mentor

So glad you're feeling better!!!

Now: 100 mg Zoloft am, 50 mg Trazodone.  Daily drug burden decreased from 2050 in 2018 mg to 150 mg 🐢🐢

Zoloft: 1/24/23 increased to 100 mg after suicide attempt 9/17/22 cut 6 mg, 8/14/22 cut 6.5 mg, 5/7/22 cut 12.5 mg 3/20/22 cut 12.5 mg 10/26/21 cut 6 mg 10/17/21 cut 5 mg, 9/17/21 Cut 3 mg,  9/13/21 cut 4 mg, 8/29/21 Cut 2 mg 8/8/21 Cut 3 mg  7/30/21 Zoloft: Converted 25 mg to liquid. Also take 100 mg pill & 25 mg pill=150 mg total
🌞 Feb 28, 2021 0 mg Gapapentin 2021 Gaba each dose 4x/day: Feb 27 7 mg (one dose only), Feb 10, 7 mg, Jan 14 10 mg 2020 Current taper schedule from Aug 30-present: drop 8 mg every 2-3 weeks. Aug 20 31 mg, Aug 18, 33 mg, July 29, 35 mg, July 23 38 mg, July 22 40 mg Jun 24 42 mg, Jun 15 44 mg, Jun 9 48 mg, May 22 50 mg, May 14 54 mg, May 7 56 mg, Apr 16 58 mg, Mar 28 60 mg, Mar 18 62 mg. Feb 26 64 mg. Feb 19, 66 mg. Jan 23, 70 mg. 2019 Dec 19, 72 mg. Nov 14 ,76 mg. Aug 8, 80 mg. Aug 6, 85 mg. Jul 26, 90 mg. Jul 11, 95 mg.

Jul 16 trazodone from 100 to 50 mg.

Jun 17-July 10 Slowly changed gab fr pill to liquid at same dose 100 mg 4x/d.

Apr 24 Stopped klon!!! 🌞 Apr 4  Decreased gaba to 400 mg (100 mg 4x/day)-Apr 4, 2019   0.25 klon March 11  Klonopin .5 mg twice daily, varied dose til Apr 15. Started Klon fast taper 25%, short use

Mar 16, 450 mg gaba 3x/day cut 600 mg--not exact!--updose after learning w/d

Feb 20, 2019 1800 mg gabapentin; MD taper; off 3 days=mvt disorder & autonomic instability. July 2018 temazepam 15 mg 1-2; prn several x/wk til Jan/Feb 2019 when cold turkey, flu illness for months

July 2018 started gabapentin 100 3x/day; titrated up to 1800 mg (600 3x/day)

Buspar, I forget how much, 2 pills a day Jan 2017-July 2018 cold turkey. On Zoloft since maybe 2004? After trying many.

*I speak from my experience. Nothing I say is medical advice. I'm not a doctor.

Link to comment

So i was feeling better as far as physical symptoms, with the exception of the genital issues.  Well, the weird arousal, funny type feeling is better,.  But i still am having very frequent urination and irritation there.  although not everyday.  yesterday i was okay, today its terrible.  Tests came back from gyno and i have ureaplasma bacteria in the genital region.  this is a bacteria that people can carry and never have an issue with, so i am questioning if maybe i am a carrier of it and the urinary troubles is really not from the bacteria?    sigh...   I really dont want to take another antibiotic.  I came out okay on the amoxicillan but it did nothing, since it wasnt the right med.    and my tinnitus has been soooo good, my mood is good.  i know antibiotics can be damaging on the ears.    I dont want to upset my applecart, but what choice do i have ?   i really wish there was a more natural way to treat these things.  

 

I feel like everytime I take a step forward, its two back.  

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

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  • Moderator Emeritus

BfromNJ,

 

I understand your feeling of things being one step forward and two steps backwards, but in the end it is all a step forward in terms of moving towards better times. 

 

I’ve done some digging online, and indeed Ureaplasma bacteria are common and don’t cause issues for most people, but if there is too much or in the wrong balance with other bacteria, they can cause symptoms like the ones you’re having. It seems there are several antibiotics that treat these infections, but not amoxicillin from what I’m seeing online.

 

I think that if the genital issues continue to be severe, you may need to consider using a non-flox antibiotic to treat the possible infection, even if it’s just to rule out what’s causing the genital issues. There is no way to know what’s causing it for sure, without either waiting it out, or trying an antibiotic suited to treating Ureaplasma infections. 

 

In terms of treating UTI’s naturally, they generally recommend drinking lots of water and ensuring you urinate as soon you feel the urge. There has always been the long-standing recommendation for cranberry juice or supplements.

 

Just some food for thought, but I think ultimately you will need to make a decision with the help of your doctors and see it out. 

Edited by eymen23

PLEASE NOTE:  I am not a medical professional.  I can only provide information and make suggestions.

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Yes I know.  Just always a concern taking yet another med.  I'm thinking my bacteria got out of whack when I stopped my probiotic.  I have since started another one.  There was an ingredient in other one that didnt agree with me.  

 

My biggest concern with antibiotics is the risk of tinnitus increasing.  

 

And of course starting another antibiotic will mean holding yet still on my taper.  

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

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  • Moderator Emeritus
8 minutes ago, BfromNJ said:

And of course starting another antibiotic will mean holding yet still on my taper.  

 

True, but equally, if you have an infection that needs drug treatment, we wouldn’t advise you to taper either. 

 

It would be sensible to be mindful of potential adverse reactions to the new probiotic. As you know, we advocate one change at a time here.

PLEASE NOTE:  I am not a medical professional.  I can only provide information and make suggestions.

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22 minutes ago, eymen23 said:

 

True, but equally, if you have an infection that needs drug treatment, we wouldn’t advise you to taper either. 

 

It would be sensible to be mindful of potential adverse reactions to the new probiotic. As you know, we advocate one change at a time here.

Yes I know.   The last one was because it contained soy.  This time no soy. What other adverse reactions might I expect from a probiotic,  aside from gastrointestinal?  

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

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  • Moderator Emeritus

There are many existing topics on this site.  I like to use google and add survivingantidepressants.org to my search term.

 

Search for probiotics and see what experiences other members have had.

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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  • Moderator Emeritus
1 minute ago, BfromNJ said:

Yes I know.   The last one was because it contained soy.  This time no soy. What other adverse reactions might I expect from a probiotic,  aside from gastrointestinal? 

 

Some probiotic strains have given me increased anxiety or depressive type symptoms. I stopped taking them, so never found out if the effect was temporary.

 

Depending on strain, they can also cause  histamine issues, I have also heard of people having brain fog in response to taking probiotics.

 

Really, there are so many probiotic strains and so many variations in our own gut microbiome, that the best feedback is to keep an eye out for any new or intensifying symptoms and try removing and re-adding the supplement if it seems to trigger issues but you are uncertain.

PLEASE NOTE:  I am not a medical professional.  I can only provide information and make suggestions.

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  • Moderator Emeritus
3 hours ago, BfromNJ said:

Well, the weird arousal, funny type feeling is better,.  But i still am having very frequent urination and irritation there.  although not everyday.  yesterday i was okay, today its terrible

BJ, I am doubtful these are symptoms of a UTI. This is, however, a known withdrawal symptom. I get it sometimes during waves. It waxes and wanes for a few days before going away. It was a symptom that, for me, came on after reinstatement, and it's more of a sensation of a "tingly" and constantly full bladder. As it starts to go away for me, I find I have to urinate constantly for several days.

 

So it could very well be just WD in your case. The fact that it varies in severity from day to day argues for it being WD rather than some type of infection. 

 

You might try drinking a glass or two of unsweetened cranberry juice per day, just to make sure your urinary tract stays healthy. In the alternative, Azo makes cranberry gummies, but they do contain a small amount of sugar (which I personally avoid).  And monitor your situation for a bit with the new probiotic on board, before you decide to add a possibly unnecessary antibiotic to the mix.

 

And as Eymen as suggested, you may want to hold off making any changes to your AD dosage at this time. I know we are all ready to "get on with it," but a couple of weeks here or there will make little difference in the overall scheme of things. 

 

Don't forget to keep notes on paper. It's especially important at this time. 

 

Sending you healing energy tonight!

2016 - Zoloft 50 mg for klonopin w/d

Approx. Nov 2017 - successful taper of klonopin; Approx. Jan. 2018 - rapid taper Zoloft over 2 wks - no w/d symptoms; May 2018 - Reinstate 50 mg Zoloft per doctor; Aug 2018 - Rapid taper Zoloft over 3-4 weeks - no w/d symptoms for 1 mo.; Late Oct 2018 - pdoc rx'd 5mg lexapro -took for 1 wk; Early Nov 2018 - Reinstate 25 mg Zoloft; updose to 37.5 on Nov 28, 2018; Nov 30 2018 - returned to 25mg Zoloft upon mod. advice; Dec 9 - Dec10 2018 - 12.5mg zoloft liquid+12.5mg zoloft pill; Dec 11 2018 - 25mg zoloft all liquid; Feb 14 2019 - updosed to 26.25 mg liquid; Mar 6 2019 - updosed to 26.88 mg liquid - new symptoms; Mar 13 2019 - back down to 26.25 mg per mod suggestion

Dose Changes: Dec 2 2019 - 5% to 25mg; Jan 14 2020 - 10% to 22.5 (increase in sxs all month); Mar 10-15? 2020,  accidental updose to 25mg; Mar 22 2020 - back down to 22.5mg; Apr 12 2020 - 2.5% to 21.94mg; Apr 19 2020 - 2.5% to 21.375mg (symptom increase); May 17 2020 - 2.5% to 20.625mg; May 24 2020 - 2.5% to 20.1mg - Jun 14 2020 - noticed uptick in symptoms settled 2 days later - July 10 2020 - onset of wave

Link to comment
11 hours ago, Dejavu said:

BJ, I am doubtful these are symptoms of a UTI. This is, however, a known withdrawal symptom. I get it sometimes during waves. It waxes and wanes for a few days before going away. It was a symptom that, for me, came on after reinstatement, and it's more of a sensation of a "tingly" and constantly full bladder. As it starts to go away for me, I find I have to urinate constantly for several days.

 

So it could very well be just WD in your case. The fact that it varies in severity from day to day argues for it being WD rather than some type of infection. 

 

You might try drinking a glass or two of unsweetened cranberry juice per day, just to make sure your urinary tract stays healthy. In the alternative, Azo makes cranberry gummies, but they do contain a small amount of sugar (which I personally avoid).  And monitor your situation for a bit with the new probiotic on board, before you decide to add a possibly unnecessary antibiotic to the mix.

 

And as Eymen as suggested, you may want to hold off making any changes to your AD dosage at this time. I know we are all ready to "get on with it," but a couple of weeks here or there will make little difference in the overall scheme of things. 

 

Don't forget to keep notes on paper. It's especially important at this time. 

 

Sending you healing energy tonight!

Yes I am holding right.  My cultures from doctor did show ureaplasma bacteria, although it could be something I normally carry, many people do.  But being i have symptoms, she wants me to take an antibiotic.  This can also be transmitted from partner sexually so that concerns me, you can see where my mind is going with that.  But that's a whole other topic.   Lol.  So yes if I must take another antibiotic, I will hold.  

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

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  • Moderator Emeritus
11 hours ago, BfromNJ said:

My cultures from doctor did show ureaplasma bacteria, although it could be something I normally carry, many people do.  But being i have symptoms, she wants me to take an antibiotic.  This can also be transmitted from partner sexually so that concerns me, you can see where my mind is going with that.  But that's a whole other topic. 

 

It might be a good idea if your partner gets tested as well, and of course treated if necessary.  No good you getting it cleared up and then getting it again from your partner.

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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8 hours ago, ChessieCat said:

 

It might be a good idea if your partner gets tested as well, and of course treated if necessary.  No good you getting it cleared up and then getting it again from your partner.

Yes Chessie, doctor even recommended that.  

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

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8/6 daily log
 
6:00- 183 mg gabapentin
-7:30- genital symptoms - arousal sensitivity- passes 
-frequent urination from awakening- persistent thru day
-tinnitus more bothersome- persists thru morning. 
10:30- tinnitus more bothersome and sensitivity to noise, dizzyness and feeling off
12:00- lots more anxiety, sense of hopelessness and depression
12:30- 183 mg gabapentin and 18.75 mg luvox
1:30- anxiety settled.  depression and hopeless feelings still continue
- tinnitus still very bad - persisted
4:00- depressive feelings lifted some 
6:00- dinner
- mood is better
8:30- 183 mg gabapentin
9:45- 25 mg seroquel
 
frequent urination and discomfort persisted all day.   very bad.  

 9/2018- lexapro low dose few days.11/3/2018- zoloft 2 days

11/7/18  - 11/15/18 - Prozac 9 days, from 10 mg for week, to 20

11/16  inpatient put on Lexapro for a few days, Cymbalta, 2 days

11/24-12/8 - gabapentin 100 mg 3xs per day - a very fast taper

1/7 - tbuspar for  three days- blurry vision, jerky eye

1/17/19 - 2/15/19- mirtazapine 15 mg - started taper on 1/30 

2/20/19 gabapentin 600 mg. .  12/20-  taper finished

2/20/19 - seroquel 25 mg current - taken  10 pm

2/20/19- luvox (generic) 25 mg.  4/6/19  to 18.75 mg .held  . Started taper again  1/7/21- 15 mg, 2/7/21- 12.5 mg, 3/7/21 -10 mg, 4/1/21- 9 mg, 5/1/21- 8.1 mg, 5/27/21- updose to 10 mg,  6/21-  in patient updose to 50 mg,  6/25/21- reduce to 10 mg (current) .  9/5- split dose 5mg am/5 mg pm.  9/20- 4 mg am/5 mg pm . 

9/1/21-  took one dose of vistril 50 mg.   

9/1/21-accidental double dose of seroquel- 50 mg 

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  • Mentor

Hang in there. Not sure re urinary symptoms--I've certainly had some on gaba. In my opinion the rest of your log is classic gabapentin withdrawal. It's evil. There are many of us out there suffering similarly, if that helps at all. A whole battalion of us invisible and silent warriors. 

Now: 100 mg Zoloft am, 50 mg Trazodone.  Daily drug burden decreased from 2050 in 2018 mg to 150 mg 🐢🐢

Zoloft: 1/24/23 increased to 100 mg after suicide attempt 9/17/22 cut 6 mg, 8/14/22 cut 6.5 mg, 5/7/22 cut 12.5 mg 3/20/22 cut 12.5 mg 10/26/21 cut 6 mg 10/17/21 cut 5 mg, 9/17/21 Cut 3 mg,  9/13/21 cut 4 mg, 8/29/21 Cut 2 mg 8/8/21 Cut 3 mg  7/30/21 Zoloft: Converted 25 mg to liquid. Also take 100 mg pill & 25 mg pill=150 mg total
🌞 Feb 28, 2021 0 mg Gapapentin 2021 Gaba each dose 4x/day: Feb 27 7 mg (one dose only), Feb 10, 7 mg, Jan 14 10 mg 2020 Current taper schedule from Aug 30-present: drop 8 mg every 2-3 weeks. Aug 20 31 mg, Aug 18, 33 mg, July 29, 35 mg, July 23 38 mg, July 22 40 mg Jun 24 42 mg, Jun 15 44 mg, Jun 9 48 mg, May 22 50 mg, May 14 54 mg, May 7 56 mg, Apr 16 58 mg, Mar 28 60 mg, Mar 18 62 mg. Feb 26 64 mg. Feb 19, 66 mg. Jan 23, 70 mg. 2019 Dec 19, 72 mg. Nov 14 ,76 mg. Aug 8, 80 mg. Aug 6, 85 mg. Jul 26, 90 mg. Jul 11, 95 mg.

Jul 16 trazodone from 100 to 50 mg.

Jun 17-July 10 Slowly changed gab fr pill to liquid at same dose 100 mg 4x/d.

Apr 24 Stopped klon!!! 🌞 Apr 4  Decreased gaba to 400 mg (100 mg 4x/day)-Apr 4, 2019   0.25 klon March 11  Klonopin .5 mg twice daily, varied dose til Apr 15. Started Klon fast taper 25%, short use

Mar 16, 450 mg gaba 3x/day cut 600 mg--not exact!--updose after learning w/d

Feb 20, 2019 1800 mg gabapentin; MD taper; off 3 days=mvt disorder & autonomic instability. July 2018 temazepam 15 mg 1-2; prn several x/wk til Jan/Feb 2019 when cold turkey, flu illness for months

July 2018 started gabapentin 100 3x/day; titrated up to 1800 mg (600 3x/day)

Buspar, I forget how much, 2 pills a day Jan 2017-July 2018 cold turkey. On Zoloft since maybe 2004? After trying many.

*I speak from my experience. Nothing I say is medical advice. I'm not a doctor.

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