lxjuice Posted April 3, 2020 Share Posted April 3, 2020 On 3/31/2020 at 3:59 PM, Pokeshaw said: Hi all - on my long slow micro taper I have been having brand Lexapro compounded. The compounding pharmacy uses a slow release filler - Methocel E4M. I am down to 0.1 mg and they cannot make capsules at lower doses. They offered an aliquot (10 caps of 0.01 mg ea) which I tried and my brain went sideways for months. I switched back to the individual capsules of 0.1 mg. I have gained some stability but seem to be experiencing both w/drawal and side effect symptoms. Over the yrs of my taper the side effect symptoms were always what prompted me to make a reduction. And i feel i need to do that soon. Unfortunately the filler Methocel E4M is not water soluble. it clumps up and really sticks to the side of the glass. Very hard to make a suspension. it only dissolves in very hot water but I dont want to do that. So I had the pharmacy make me 0.1mg caps in Methocrystalline cellulose which dissolves nicely in water but is fast release. I am trying to transition over by taking it (capsules for now with the idea of dissolving in water later) every 3 days but already feeling w/drawal aggravation. Not sure how to do this? Is there a way to make a suspension with the slow release Methocel E4M filler? Or should I go more slowly with the transition from the slow release to fast release capsules? Any ideas would be very helpful! Thank you! Poke Escitalopram has a half life of somewhat over 24 hours, you could switch to twice a day liquid dosing to stabilize the blood concentrations more. You wouldn't have been able to make a liquid from the methocel E4M solution even if it hadn't clumped up because you would have lost the slow release. The only way I can think you can transition from slow release to fast release is if you take the 0.01mg aliquots every 2.4 hours and then reduce the time between them until you are taking 10 aliquots at once, then you can direct swap to 0.1mg IR/liquid. You would have to set an alarm at night though. You could try taking them every 1.6 hours for the 16 hours you're awake but there will be a bigger immediate adjustment before you can shrink the schedule. Dx: complex PTSD Discontinuation/taper history: sertraline, trazodone, prazosin, mirtazapine, diazepam Took 200mg quetiapine for 0.5 years and 150mg for 1.5 years until 01/2020. Now microtapering daily at an overall rate of 12.5mg/month. Link to comment Share on other sites More sharing options...
Pokeshaw Posted April 6, 2020 Share Posted April 6, 2020 Hi LX - Thanks for getting back to me. I can't use the liquid since it only comes in generic and I had a bad reaction to it back a few yrs ago. I have been using brand Lexapro for the compounding. Also, I had tried the aliquot the pharmacy made for me over a year ago and was not able to stabilize on it so I went back to individual caps of 0.1 mg Here's what I've been doing - and so far so good. for a couple weeks I took the 0.1 mg fast release every 3 days and the other days I stayed with the 0.1 mg slow release. It was a bit bumpy as I mentioned in my post but then that passed. So I waited a few days and then I moved to every other day and that is where i am now. Doing OK Will stay here another week or so and then when I feel OK go to daily on the fast release. Will stay there until I feel pretty stable before starting to dissolve in water and do reductions. One of the big 'side effect' issues for me that always indicated it was time to make a reduction is the 'lexapro clench'. Neck arms jaw and all the issues that ensue such as carpal tunnel, nerve pain and TMJ. all stuff i suffered with along with constipation when I was on full dose of Lexapro and all went away when i stopped. unfortunately i stopped too fast and then went into a horror show of w/d. Then reinstated months later and have been on this seesaw of tapering and dealing with w/d and side effect symptoms for yrs. This final stretch is very hard! But good to have someplace to check in where people have a clue about this! I have ordered a graduated cylinder and some oral syringes and have been reading about how to do it. But I'm sure I will post again once i get to the dilution phase. Take good care and thank you again for responding! Poke 7 yrs Lexapro 10 mg. Mar/2011 - 1 month taper. Severe W/D. Multiple symptoms.Gallbladder and parathyroid surgery in Aug and Oct. Disability 3 months. Dec/2011 reinstated 5mg Lex and went back to work. very bad shape. By Aug/2012 - self tapered to 1.25 mg cutting pills. -very bad shape. Nov/2012 Dr. Hinz neuro-replete. up and down. Aug/2013 at aprox 1.0 mg Lex stopped neuro-replete ~Oct 2013 Found this site ~ began using compounded Lexapro and have been micro tapering since then and holding as needed. 11/6/2013 - 0.6 mg 2/1/2018 - .135 mg Now reducing 5-10% per month 4/1/18 - .1 mg 4/17/18 - changed delivery from compounded individual caps to aliquot. went from .1 mg to .09 aliquot 7/4/2018 - .09 mg Holding due to wave of W/D symptoms 7/22/18 updosed to .1 mg aliquot 9/30/18 - reduced to .0975 aliquot 2/1/19 - updosed to .1 mg aliquot due to instability bad wave W/D 9/12/19 - back to .1 mg individual caps since could not get stable using aliquot Link to comment Share on other sites More sharing options...
Johni Posted May 6, 2020 Share Posted May 6, 2020 (edited) Don't you know that cipralex is soluble in water? MOD NOTE: This is incorrect. Please see this post: Edited July 10, 2020 by ChessieCat added mod note 2023.01.27 1,6 mg 2023.01.29 1,5 mg 2023.02.27 1,35 mg 2023.03.30 1,2 mg 2023.04.18 1,1 mg 04,26 1,05 mg 2023.01.26 1,05 mg 2023.02.27 .27 .20. .21 0,8 mg 2023.07.14 0,65 mg 2023.08.20 0,45 mg 2023.09.20 0,25 mg 2023.11.14 000000000!!!!! Link to comment Share on other sites More sharing options...
Moderator brassmonkey Posted May 6, 2020 Moderator Share Posted May 6, 2020 Sorry Johni, but that isn't true. According to rxlist.com Escitalopram oxalate occurs as a fine, white to slightly-yellow powder and is freely soluble in methanol and dimethyl sulfoxide (DMSO), soluble in isotonic saline solution, sparingly soluble in water and ethanol, slightly soluble in ethyl acetate, and insoluble in heptane. (RED highlight added) Your best bet would be to use a homemade isotonic saline solution (9% salt in water) as methanol is poisonous and DMSO is hard to get and hard to work with. 20 years on Paxil starting at 20mg and working up to 40mg. Sept 2011 started 10% every 6 weeks taper (2.5% every week for 4 weeks then hold for 2 additional weeks), currently at 7.9mg. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013. Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). I added in an extra 6 week hold when I hit 10mg to let things settle out even more. When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks. The 3 + 3 schedule turned out to be too harsh so I cut back to dropping 1mgpw every 4 weeks which is working better. Final Dose 0.016mg. Current dose 0.000mg 04-15-2017 "It's also important not to become angry, no matter how difficult life is, because you can loose all hope if you can't laugh at yourself and at life in general." Stephen Hawking Link to comment Share on other sites More sharing options...
Bruci Posted September 22, 2020 Share Posted September 22, 2020 I’m having a bit of trouble finding information on the forum so excuse me if someone has already answered this. I would like to make a suspension of Celexa for tapering. A compounding pharmacist told me that a suspension will not last longer than two weeks. Has anyone else been told this? I am at the beginning of my taper from 30 mg down to zero. Is there a guide somewhere here on how to make appropriate suspensions without waste? Bruci 1980s: First diagnosed with depression. Treated with a tricyclic. 1988: Switched to Prozac 20 mg. 1990s to 2010: On and off Prozac. Increased dose led to side effects. 2011: Put on Zyprexa. 2011: Work burnout and breakdown. Hospitalized for suicidal depression. Switched to Seroquel. Switched to Celexa 40 mg and lithium 300 mg. 2019: Stopped Seroquel. 2020 July: Decreased Celexa to 30 mg in attempt to alleviate sexual dysfunction. Worked somewhat. 2020 August: Decreased Celexa to 20 mg. Sexual function improved but w/d effects started. 2020 September: Maintaining Celexa at 20 mg. Experiencing w/d effects - fatigue, dysphoria, mood instability 2020 September 13: Increased Celexa to 30 mg due to w/d effects. Still on lithium 300 mg/day. 2020 October 3: Reduced Celexa to 27 mg. Started taper. 10% per month as recommended. 2020 October 18: Reduced to 24 mg. 2020 December 4: Reduced to 21 mg. 2020 December 23: Reduced to 20 mg (spacing out taper intervals due to persistent w/d effects) 2021 September 23: Several reductions over the past 9 months to 7.0 mg. Stressful life circumstances led me to feeling very depressed with suicidal feelings, so upped to the dose to 10 mg until I feel better. Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted September 22, 2020 Moderator Emeritus Share Posted September 22, 2020 30 minutes ago, Bruci said: I would like to make a suspension of Celexa for tapering. Check out Post #1 of this topic. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
DavidH888 Posted October 24, 2020 Share Posted October 24, 2020 Hello, Can anyone tell me how much water I should use to make a solution from 150mg Effexor HCL? Can I use distilled water? October 2020 - Present - 150mg HCL Effexor Most of 2019 - 60mg of Cymbalta 2011-2019 - 200mg of Zoloft 2011-2019 - 2mg Risperdone 2020-present - 5mg Abilify 2011-presnent - 2-3mg of clonazepam Prior to 2011: Can't remember exact dates, but I was on Prozac and Wellbutrin Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted October 25, 2020 Moderator Emeritus Share Posted October 25, 2020 If you haven't already done so, please check out this topic from the beginning because there is a lot of information already provided. You can use any amount of water that you want, but it needs to be enough to dissolve the dose. The more water you use the more accurate the dose you can get. You can use distilled or bottled if you prefer, I'm using tap water here in Australia and it seems to be fine, kept covered in refrigerator. As a guideline: 150mL of water with 150mg of drug will give you a 1:1 ratio. This means that each 1mL of liquid will give you 1mg dose. If you double the water: 300mL of water with 150mg of drug will give you a 2:1 ratio. This means that each 1mL of liquid will give you 0.5mg dose. Or the other way around, 2mL liquid will give you 1mg dose. If you halve the water: 75mL of water with 150mg of drug will give you a 1:2 ratio. This means that each 1mL of liquid will give you 2mg dose. Or the other way around, 0.5mL of liquid will give you a 1mg dose. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
DavidH888 Posted October 26, 2020 Share Posted October 26, 2020 Thanks for your help! Just one last question, since I have HCL capsules, should I empty the capsules into the water? Or leave it in? October 2020 - Present - 150mg HCL Effexor Most of 2019 - 60mg of Cymbalta 2011-2019 - 200mg of Zoloft 2011-2019 - 2mg Risperdone 2020-present - 5mg Abilify 2011-presnent - 2-3mg of clonazepam Prior to 2011: Can't remember exact dates, but I was on Prozac and Wellbutrin Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted October 26, 2020 Moderator Emeritus Share Posted October 26, 2020 (edited) Generally you empty the contents but sometimes they are hard to open and sometimes some of the contents gets stuck inside. The gelatin capsule may not "dissolve" because you will be using cold water. Gelatin dissolves/melts better with heat. If you can't get the contents out you could try putting in the whole capsule but it would be better without. Edited October 26, 2020 by ChessieCat * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted October 27, 2020 Moderator Emeritus Share Posted October 27, 2020 (edited) Well I received my two graduated cylinders today, both 100mL volume, plastic. One of them has a wobbly base. I've even placed in hot water then put it into a flat based container, pressed down on it and poured refrigerated water over it and it still won't sit flat. I'm going to request a refund for one of them because it's not accurate, which is exactly why I was buying them. 😏 Edited to add: I was able to take a fairly good photo showing that the bottom wasn't sitting properly and the seller has refunded me half of the money so I've only had to pay for the okay one. I've put it aside as a spare in case I ever need it (might come in handy for something else - if I throw it away I'll end up needing it or finding a use for it 🤣). I did think of trying to file off some of the bottom but didn't think it was worth the effort. However, I did find that if I press the base to the table it will sit flat long enough for me to pour in the water and measure it. Edited October 27, 2020 by ChessieCat * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted October 28, 2020 Moderator Emeritus Share Posted October 28, 2020 Well I used my graduated cylinder for the first time this morning and found it difficult to get the exact amount of liquid measured. I tried using the second (faulty) cylinder to top it up to the 100mL mark but it was difficult to control the amount of liquid I tipped in. So I had a bright idea 💡: HELPFUL TIP: When using a graduated cylinder it can be difficult to fill it to the exact measurement you need. To make this easier to do, use a medicine eye dropper so you can gradually add more water a drop at a time. TA DAH!!! * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted October 28, 2020 Moderator Emeritus Share Posted October 28, 2020 On 10/26/2020 at 11:00 AM, DavidH888 said: Thanks for your help! Just one last question, since I have HCL capsules, should I empty the capsules into the water? Or leave it in? @DavidH888 I did a test this morning and put my empty gelatin capsule into water (straight from the tap) to see what happened. It softened but did not dissolve. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
DavidH888 Posted November 10, 2020 Share Posted November 10, 2020 Is it possible to make a solution from Effexor XR? I read that it won't work with extended release capsules. How can I tape then? October 2020 - Present - 150mg HCL Effexor Most of 2019 - 60mg of Cymbalta 2011-2019 - 200mg of Zoloft 2011-2019 - 2mg Risperdone 2020-present - 5mg Abilify 2011-presnent - 2-3mg of clonazepam Prior to 2011: Can't remember exact dates, but I was on Prozac and Wellbutrin Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted November 10, 2020 Moderator Emeritus Share Posted November 10, 2020 (edited) Please read Post #1 of tips-for-tapering-off-effexor-and-effexor-xr-venlafaxine ehich contains a lot of information about how to get the dose you need. Edited November 10, 2020 by ChessieCat * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
bubbles Posted November 11, 2020 Share Posted November 11, 2020 Just a note that my ground up sertraline tablets took about 3 days to thoroughly dissolve/disperse in the suspension I used. Will have to be organised in future! Looks thoroughly distributed now. I ground it first with mortar and pestle. In future will grind more to see if I can avoid those bits that took longer as I imagine they should have been visible and perhaps the dissolve time could be shortened. 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted November 12, 2020 Moderator Emeritus Share Posted November 12, 2020 (edited) Are you could buy a grinder. That might be better. But then again if you are only doing one tablet it probably wouldn't be as good at the mortar and pestle. Just found this. They suggest wetting the tablet to make it softer. Obviously you'd have to use a measured amount. How to Crush a Pill: 14 Steps (with Pictures) - wikiHow https://www.wikihow.com/Crush-a-Pill Use a small bowl-spoon or mortar-pestle method. Place your pill in a clean, dry cup or mortar. Soak the pill in a small amount of water for five minutes. This is optional but may help soften the pill. Less pounding/grinding may be required too. Edited November 12, 2020 by ChessieCat * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
Moderator Emeritus hayduke Posted December 21, 2020 Moderator Emeritus Share Posted December 21, 2020 (edited) Titled: Adjustable volume pipette How'd it take me so long to find these! Can be found relatively inexpensive for our purposes. Now it's as simple as measuring out 25ml for the base volume in my old glass pipette and putting into my fridge storage bottle, cracking open and suspending the 2.5mg tablet in there, mixing thoroughly then dialling in 0440 on the device, drawing it out, ingesting my 0.44mg and I'm done for the night. https://en.wikipedia.org/wiki/Pipette#Air_displacement_micropipettes While it's fundamental to understand the manual process this is super simple at bed time and easy to travel with. Cheers Edited December 21, 2020 by manymoretodays added title, merged with topic I am not a health professional - your actions are your own. Please do not seek tapering support via private message - "Any reason to hold is a good one" My taper visualised as a graph | My intro thread Backdrop: 2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole 2015: olanzapine 10 -> 7½ -> 6⅔ -> 5mg by crude pill cutter 2018: Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold Jan 2019 2.50mg water titration -> Jan 2020 1.214 -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂 Jun 2023 💉150mg paliperidone "loading" depot shot, 100mg 1wk after Jul 100mg Aug-Dec 75mg/4wks Jul 2023 2.50mg aripiprazole/day attempt to lower prolactin^ Jan-Feb 2024 cross taper off shots to 1mg risperidone Ask not what you can do for your country, but what your country did to you" -- KMFDM Link to comment Share on other sites More sharing options...
Moderator Emeritus manymoretodays Posted December 21, 2020 Moderator Emeritus Share Posted December 21, 2020 Thanks @hayduke Where did you find them? Do tell. And then, I"ll go ahead and add this information, to post one of this topic too. Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks. Started with psycho meds/psychiatric care circa 1988. In retrospect, and on contemplation, situational overwhelm. Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time). 5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014) 12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs. My last psycho med ever! Tapered @ 10% every 4 weeks, sometimes 2 weeks to 2016 Dec 16, medication free!! Longer signature post here, with current supplements. Herb and alcohol free since 5/15/2016. And.....I quit smoking 11/2021. Lapsed. Redo of quit smoking 9/28/2022, and again finally 5/25/24. Can you say Hallelujah?(took me long enough)💜 None of my posts are intended as medical advice. Please discuss any decisions about your medical care with a knowledgeable medical provider. My success story: Blue skies ahead, clear sailing Link to comment Share on other sites More sharing options...
Moderator Emeritus hayduke Posted December 21, 2020 Moderator Emeritus Share Posted December 21, 2020 Hi @manymoretodays Plenty here I spent around 40AUD and can't complain for what I got. If it doesn't hold up to this light household use I'll report back. So far, so good. Cheers I am not a health professional - your actions are your own. Please do not seek tapering support via private message - "Any reason to hold is a good one" My taper visualised as a graph | My intro thread Backdrop: 2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole 2015: olanzapine 10 -> 7½ -> 6⅔ -> 5mg by crude pill cutter 2018: Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold Jan 2019 2.50mg water titration -> Jan 2020 1.214 -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂 Jun 2023 💉150mg paliperidone "loading" depot shot, 100mg 1wk after Jul 100mg Aug-Dec 75mg/4wks Jul 2023 2.50mg aripiprazole/day attempt to lower prolactin^ Jan-Feb 2024 cross taper off shots to 1mg risperidone Ask not what you can do for your country, but what your country did to you" -- KMFDM Link to comment Share on other sites More sharing options...
HardTimes Posted January 10, 2021 Share Posted January 10, 2021 Question: How long does the suspension/solution last? Apologies if this has been answered - I searched but found nothing so far. I've been successfully making suspensions of Citalopram, where a 20mg tablet is put into 80ml of water (so: 10mg = 40ml, 1mg = 4ml, 0.5mg = 2ml, etc.). A couple of days ago I tried to go UP from 0.75mg to 1mg (as I'm trying to reinstate and stabilize). I was doing comparatively well at 0.75 for over two weeks, and thought a bump up would further resolve my symptoms. However, I quickly had a reaction to the increased dose (heart palps, jittery, nervous, felt like some sort of bad "high"). But that was also a fresh batch of solution. So I'm wondering if the efficacy of the solution goes down over time or not? Meaning a fresh batch might pack a larger punch? Theoretically, taking 1mg per day would mean the solution could last for 20 days (though I've generally made a new batch after 10-12 days). I'm too new at this to notice whether a fresh batch had a larger impact previously. I keep the solution in the fridge, as suggested. SO: Does the efficacy of the solution diminish over several days? Meaning a fresher batch is more powerful? Or perhaps my reactions are just fairly coincidental, part of the waves and windows randomness of this whole thing? (And FYI: I dropped right back to 0.75 the next day, but am still feeling super depressed, with weird bouts of nervousness, boiling blood, hot flashes, self-loathing thoughts, etc etc... THIS STINKS!) 15+ years Citalopram 10mg (sometimes 20?) 2019 Citalopram 5mg. No problem reduction. 2020 Citalopram 5mg to zero. (Feb) 2020 (Feb - mid Oct): Very rare use of 0.125 or .25mg Xanax for really bad symptoms 2020 (Feb - Nov): Occasional use of "Nytol" sleep aid (an antihistamine). 2020 Failed reinstatement: Escitalopram by accident (not Citalopram). -- using a scale, started July 27 0.5mg, doubled every week or so to reach 5mg by Aug 30. Too fast - terrible depression, quit. 2020 (Oct-current): Supplements: -- Morning: Magnesium 300mg, Omega 3(483 EPA, 360 DHA +Vit E) Night: Liquid Valerian/Passiflore/Escholtzia - French organic herbal sleep aid, 1.9mg LD Melatonin 2020 Current - new Citalopram reinstatement. (Accidentally started with Escitalopram before realizing and switching to Citalopram Oct. 30) -- using pipette method: Oct 30, 0.25mg; Nov. 4th, 0.375; Dec. 1st 0.5mg, Dec. 21st 0.75mg Jan 19: Decide reinstatement fail: Jan 21 0.625mg, Jan 28: 0.5mg Feb 8 0mg Link to comment Share on other sites More sharing options...
Moderator Emeritus manymoretodays Posted January 10, 2021 Moderator Emeritus Share Posted January 10, 2021 Hi HardTimes, I went ahead and quoted you over to your Introduction topic and answered there. Best, mmt Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks. Started with psycho meds/psychiatric care circa 1988. In retrospect, and on contemplation, situational overwhelm. Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time). 5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014) 12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs. My last psycho med ever! Tapered @ 10% every 4 weeks, sometimes 2 weeks to 2016 Dec 16, medication free!! Longer signature post here, with current supplements. Herb and alcohol free since 5/15/2016. And.....I quit smoking 11/2021. Lapsed. Redo of quit smoking 9/28/2022, and again finally 5/25/24. Can you say Hallelujah?(took me long enough)💜 None of my posts are intended as medical advice. Please discuss any decisions about your medical care with a knowledgeable medical provider. My success story: Blue skies ahead, clear sailing Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted January 23, 2021 Moderator Emeritus Share Posted January 23, 2021 I have discovered that there are a couple of things that you need to be careful of when taking liquid. No 1 make sure that the syringe is not pointed to the back of your throat so that you end up coughing. For me it was an issue for at least 1/2 hour which made it difficult to relax and settle down to sleep. No 2 make sure that the syringe is pointed into the mouth so that the liquid does not hit the side of you mouth or teeth and some of it splashes out of your mouth. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
bubbles Posted January 28, 2021 Share Posted January 28, 2021 On 1/24/2021 at 7:50 AM, ChessieCat said: I have discovered that there are a couple of things that you need to be careful of when taking liquid. No 1 make sure that the syringe is not pointed to the back of your throat so that you end up coughing. For me it was an issue for at least 1/2 hour which made it difficult to relax and settle down to sleep. No 2 make sure that the syringe is pointed into the mouth so that the liquid does not hit the side of you mouth or teeth and some of it splashes out of your mouth. Oh no! I've been doing two things - sometimes squirting the liquid from the syringe straight into my mouth. More often I squirt it into a little medicine measure cup, and then I add water, drink whole thing, add more water, repeat another time or two - to make sure I'm getting all of the drug. 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid Link to comment Share on other sites More sharing options...
bubbles Posted January 28, 2021 Share Posted January 28, 2021 On a different topic, I have a bit of a conundrum. The issue is because I'm feeling a bit uncertain if I'm getting the volumes correct - with all my adding a bit here and there I'm wondering if I'm ending up with less than I think. Am I starting each subsequent "bit" with a little left on the sides of the measuring cup? I think if I can work out how much volume the ground up tablet takes, I can simplify my process. To work that out, I think if I start with, say, 2ml of water in a medicine measuring cup, add a ground up tablet, and then draw it up into 1ml syringes, I should be able to work out how much extra I have as compared to the original 2ml. I don't think it would matter if it wasn't even fully ground up as long as all the bits go into the syringe. Does that seem reasonable? If I can determine that, say, the tablet volume is 0.3ml, then I can simplify my process in making up the suspension. I could first grind up the tablet and put it in to the bottle, then add 49.7ml or whatever amount of liquid I've determined I need using (larger) syringes and that will eliminate the "some left on the sides of the medicine measure" issue. The 1ml syringes have graduations down to 1% of 1ml, so it should be fairly accurate. I'm also not sure if I should do this now, with water, and sacrifice a tablet, or just do this next time when I make up my next bottle and just be very careful. Hmmm. I am using up to 50% water when making up the suspension (so as to make the Ora Plus last as long as I reasonably can). 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid Link to comment Share on other sites More sharing options...
Moderator Emeritus hayduke Posted January 28, 2021 Moderator Emeritus Share Posted January 28, 2021 @bubbles interesting question. I was thinking your hypothesis might account for noticing a difference in taking the same tablet in different volumes of water (say when going from 50 ml to 25 ml base volume), but given how some people struggle with the full amount of the tablet once they make the switch to suspension and drink it all, there might be more in play than that. I've always treated the tablet's volume as negligible. It's probably more important to be consistent through the taper rather than have absolute accuracy at any point - our bodies probably care more about keeping the relative dosages accurate as we taper. I am not a health professional - your actions are your own. Please do not seek tapering support via private message - "Any reason to hold is a good one" My taper visualised as a graph | My intro thread Backdrop: 2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole 2015: olanzapine 10 -> 7½ -> 6⅔ -> 5mg by crude pill cutter 2018: Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold Jan 2019 2.50mg water titration -> Jan 2020 1.214 -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂 Jun 2023 💉150mg paliperidone "loading" depot shot, 100mg 1wk after Jul 100mg Aug-Dec 75mg/4wks Jul 2023 2.50mg aripiprazole/day attempt to lower prolactin^ Jan-Feb 2024 cross taper off shots to 1mg risperidone Ask not what you can do for your country, but what your country did to you" -- KMFDM Link to comment Share on other sites More sharing options...
bubbles Posted January 29, 2021 Share Posted January 29, 2021 @hayduke Ultimately I'm trying to make a 1ml=1mg suspension, so I'm taking a 50mg tablet and using Ora Plus to make up the 50ml (or rather Ora Plus diluted with the up to 50% as per manufacturer instructions). I've been trying to achieve the kind of accuracy that a compounding pharmacy might achieve, which is not very realistic. I agree that consistency is likely (by far) the most important thing so treating the tablet as "nil" is probably smarter. Whatever is the "baseline", I'll adapt to it as long as it's consistent. Actually, since treating the tablet as negligible volume will make a fractionally less potent suspension, it will make my jump off dose slightly lower, which can only be a good thing at that end of the process. I'm also going to buy larger syringes and use them to measure out the suspension instead of using the medicine measuring cup since I think that will be more accurate. 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid Link to comment Share on other sites More sharing options...
Moderator Emeritus hayduke Posted January 29, 2021 Moderator Emeritus Share Posted January 29, 2021 @bubbles you might want to look at the adjustable volume pipettes I linked above. Way less of a production titrating around bed time. Cheers I am not a health professional - your actions are your own. Please do not seek tapering support via private message - "Any reason to hold is a good one" My taper visualised as a graph | My intro thread Backdrop: 2003 10mg olanzapine | 2004 2-3mg risperidone | end 2014 3wks aripiprazole 2015: olanzapine 10 -> 7½ -> 6⅔ -> 5mg by crude pill cutter 2018: Mar 5.00mg -> water titrated taper -> Aug2.5mg tablet and hold Jan 2019 2.50mg water titration -> Jan 2020 1.214 -> Jan 2021 0.44 -> 2 Oct 0.205 ->3 Oct ZERO🥂 Jun 2023 💉150mg paliperidone "loading" depot shot, 100mg 1wk after Jul 100mg Aug-Dec 75mg/4wks Jul 2023 2.50mg aripiprazole/day attempt to lower prolactin^ Jan-Feb 2024 cross taper off shots to 1mg risperidone Ask not what you can do for your country, but what your country did to you" -- KMFDM Link to comment Share on other sites More sharing options...
bubbles Posted January 30, 2021 Share Posted January 30, 2021 23 hours ago, hayduke said: @bubbles you might want to look at the adjustable volume pipettes I linked above. Way less of a production titrating around bed time. Cheers I bought a 25ml syringe and a 5ml syringe, so making up my 50ml suspension (which lasts about a month, or at least it should, lol) is going to be a whole lot easier. I have a packet of expired tablets that I've been hanging on to (lots of meds last just fine after their purported expiry date, though I have no idea if sertraline is one of them) - they are approximately the same size/shape as the batch I'm currently using. I started with 2ml of water and one of the crushed (expired) sertraline tablets. 2ml of water wasn't enough as I had some tablet powder left in the medicine measuring cup after drawing up the contents so it was imperfect, but looks like the tablet takes up a bit under 0.1ml. That means that, yes, considering it as nil makes an imperfect 50:50 suspension. It will make 50.1ml = 50mg, which means each 1ml actually equals 0.998004mg, but since I'm not a compounding pharmacy that's a degree of accuracy I can't hope to achieve anyway so I will ignore that and consider it 1:1. From the next batch I will do this: Disinfect bottles etc with baby bottle disinfection tablets, leave (covered with a clean tea towel or a paper towel) to air dry until completely dry (about 24 hours) Crush up a tablet using a mortar and pestle (with the mortar lined with baking paper to aid in pouring into the bottle) Try to get the powder directly into the bottle I'm using Add 50ml of Ora Plus, or Ora Plus and water (cooled, previously-boiled water is probably best?) to the recommended ratio of up to 50% water Shake before use to distribute the powder as thoroughly through the suspension I try to do it a day or two earlier than needed to give any bigger tablet fragments. I like to dilute the Ora Plus as recommended to make the expensive Ora Plus last longer. 2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012 January 2013 started Sertraline, over time worked up to 100mg July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg 2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg, July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg) 2021 Some time in about Jan/Feb realised probably on more like 1.8mg and poss mixing error in making suspension; doses after 10 Feb accurate; 10 Feb 1.6mg; 7 Mar 1.4, continued monthly 10% drops until 1mg, then dropped 0.1mg monthly. May 2022,0.1mg, now dropping 0.01mg per week 29 August 2022 - first day of zero! My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/21/ Current: Armour Thyroid Link to comment Share on other sites More sharing options...
Sacam7 Posted February 2, 2021 Share Posted February 2, 2021 I’m trying to wrap my fried brain around all of this. I have read everything at least a few times. Some things I hope can be clarified. I am taking 20 mg of paxil (paroxetine) a day. If I want to make a liquid, can I just do it with my one 20mg pill every day, ingest what I need, and throw out the rest? I see people asking about storing the liquid, but I’m wondering if I can just make it every day from my one pill, and take my reduction. I’m terrible at math and conversion s and all that so I will be asking for a lot of help here (sorry) I’m not sure if it would be easier for me to just crush and weigh. But if someone can help me figure out the making the liquid, that would be so appreciated. Another question, does the brass monkey slide method work well with making your own liquid? How do you do the calculations for a 2.5% drop on a liquid? What is the best ratio for this? Thank you for any answers. I am completely lost and I’m so embarrassed. Paxil 20mg since 2000 (20 years) September 2001 - February 2003 - Klonopin - half of a .5 mg tablet three times a day March 2012 - Klonopin - .5mg tablet once or twice a day for two weeksoct. 2014- cold turkey off of 20mg paxil November 2014-reinstated paxil 5,10,20mg June 2020- went down to 22.5mg paxil august 2020-went down to 20 mg paxil. Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted February 2, 2021 Moderator Emeritus Share Posted February 2, 2021 @Sacam7 I'll respond in your Intro topic * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
Janece Posted February 9, 2021 Share Posted February 9, 2021 Ok so to make my own liquid suspension with water to taper slowly .. I should do a 1:1 ration right ? Which mean if I want to taper off 150mg then I would need to add the 150 mg tablet to 150mg of water right? March 2017- Aug 2017 benztropine 1mg, clonazepam 1mg, divalproex 500mg, haloperidol 5mg Aug 2017-Dec 2018 benztropine .5mg, clonazepam .5mg, divalproex 500mg, haloperidol .5mg May 2019 - Dec 2020 haloperidol .5mg , Oxcarbazapine 150mg Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted February 10, 2021 Moderator Emeritus Share Posted February 10, 2021 You can make any ratio that you want or is best for the dose you need. Sometimes it is easier to measure the dose you need if you use more water. I've been making a 1:100 ratio using the contents of 2mg compounded Pristiq capsules with 200mL water for the last few reductions but this time I've used 400mL, a 1:200 so that instead of measuring 11.5mL of liquid I can measure 23mL. It's not just easier but more accurate. Making a 10% reduction will be 135mg, so making a 1:1 ratio for that reduction should work okay. However the next one will be 121.5mg. You could make a 1:2 ratio. 150mg tablet in 300mL water so each 1mL contains 0.5mg = 2mL contains 1mg ) so to get 121.5mg you would take 243mL liquid. However if you decide to round the amount always round up so that you reduce less than 10% not more. And remember to calculate the next reduction on the rounded up amount. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
Janece Posted February 10, 2021 Share Posted February 10, 2021 33 minutes ago, ChessieCat said: You can make any ratio that you want or is best for the dose you need. Sometimes it is easier to measure the dose you need if you use more water. I've been making a 1:100 ratio using the contents of 2mg compounded Pristiq capsules with 200mL water for the last few reductions but this time I've used 400mL, a 1:200 so that instead of measuring 11.5mL of liquid I can measure 23mL. It's not just easier but more accurate. Making a 10% reduction will be 135mg, so making a 1:1 ratio for that reduction should work okay. However the next one will be 121.5mg. You could make a 1:2 ratio. 150mg tablet in 300mL water so each 1mL contains 0.5mg = 2mL contains 1mg ) so to get 121.5mg you would take 243mL liquid. However if you decide to round the amount always round up so that you reduce less than 10% not more. And remember to calculate the next reduction on the rounded up amount. Ok I see, but what I dont understand is how do you calculate the percentage ? March 2017- Aug 2017 benztropine 1mg, clonazepam 1mg, divalproex 500mg, haloperidol 5mg Aug 2017-Dec 2018 benztropine .5mg, clonazepam .5mg, divalproex 500mg, haloperidol .5mg May 2019 - Dec 2020 haloperidol .5mg , Oxcarbazapine 150mg Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted February 10, 2021 Moderator Emeritus Share Posted February 10, 2021 10% reduction: 150mg x 0.9 = 135mg 5% reduction: 150mg x 0.95 = 142.5mg * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
Janece Posted February 10, 2021 Share Posted February 10, 2021 5 minutes ago, ChessieCat said: 10% reduction: 150mg x 0.9 = 135mg 5% reduction: 150mg x 0.95 = 142.5mg So when I try to multiply 150 by 0.10 it gives me 15 , you would think that if you want to reduce by 10% you would multiply by 10 but its 9 I dont understand that and when it comes to reducing my 5% you multiplied by 0.95 which is a bigger number and a different equation . So to get 5% multiply by 0.95 how come to get 10% multiply by 0.100 doesn't work... I'm gonna use you're equations and tha k you but I really want to understand. March 2017- Aug 2017 benztropine 1mg, clonazepam 1mg, divalproex 500mg, haloperidol 5mg Aug 2017-Dec 2018 benztropine .5mg, clonazepam .5mg, divalproex 500mg, haloperidol .5mg May 2019 - Dec 2020 haloperidol .5mg , Oxcarbazapine 150mg Link to comment Share on other sites More sharing options...
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